Aggregatibacter aphrophilus NJ8700: NT05HA_0176
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Entry
NT05HA_0176 CDS
T00929
Name
(GenBank) glutamate--cysteine ligase/gamma-glutamylcysteine synthetase
KO
K01919
glutamate--cysteine ligase [EC:
6.3.2.2
]
Organism
aap
Aggregatibacter aphrophilus NJ8700
Pathway
aap00270
Cysteine and methionine metabolism
aap00480
Glutathione metabolism
aap01100
Metabolic pathways
aap01240
Biosynthesis of cofactors
Brite
KEGG Orthology (KO) [BR:
aap00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
NT05HA_0176
09106 Metabolism of other amino acids
00480 Glutathione metabolism
NT05HA_0176
Enzymes [BR:
aap01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.2 glutamate---cysteine ligase
NT05HA_0176
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GFIT
Motif
Pfam:
Glu_cys_ligase
ATP-grasp_6
RimK
Dala_Dala_lig_C
ATP-grasp_3
ATPgrasp_ST
GARS_A
ATP-grasp
Motif
Other DBs
NCBI-ProteinID:
ACS96614
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Position
168842..171115
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AA seq
757 aa
AA seq
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MNIQQVIKENRLELLFQQGSFGIEKESQRVHADGSIVVTEHPKCFGSRSYHPYIQTDFAE
SQLELITPPNKKIEDSLRWLSAIHEVVLCSLPEDEFIFPLSMPAGLPPEDQIKVAQLENP
ADVAYREHLVASYGKNKQMVSGIHYNFQLEPTFIQQLFAQQNTYQSAVDFQNDLYLKVAR
NFLRYQWILVYLLAATPTVDANYFRHGTPLKAGQYVRSLRSSQYGYVNDPSVKVSYDSLN
DYVKTLEHAVSSGQLIAEKEFYSNVRLRGAKHARELLQNGIQYLEFRLFDLNPFEAYGIA
LNDAKFVHYFILLMAWLDEESLASAVDLGKEKLAQVAWENPLSATAFQAEGERILQQLLA
MLTEINADVEIEAIVKDKLVQFAEPSQTLGARLVKAIEAHGGYQKLGAELAIRYKQRAFE
RFYALSAFDNMELSTQALMFDAIQKGLKMEILDERDQFLSLQFGDHLEYVKNGNMTSHDS
YISPLIMENKVVTKKVLAKAGFNVPQSVEFTSVEQAVANYALFAGRAVVIKPKSTNYGLG
ISIFQQGVHDREDFAKAIEIAFREDKEVMVEDYLTGTEYRFFVLGDETLAVLLRVPANVI
GDSVHTVAELVAQKNDHPLRGDGSRTPLKKIALGDIEQLQLKEQGLTVDSVPAKDQLVQL
RANSNISTGGDSIDMTDQMHPSYKALAVGITKAMGAAVCGVDLIIPDLTKPAEPSLQSWG
VIEANFNPMMMMHIFPYAGQSRRVTQNVLKMLFPELK
NT seq
2274 nt
NT seq
+upstream
nt +downstream
nt
atgaatattcagcaggttataaaagaaaatcgcttggagcttttgttccaacaaggctca
ttcggtattgaaaaagaaagtcagcgcgtgcacgcagacgggtctattgtggttaccgag
cacccaaagtgttttggcagccgttcttatcatccttacattcaaacagattttgctgaa
agccaacttgagttaatcaccccgccaaataaaaagattgaagatagcctgcgttggtta
tccgctattcatgaagtggtgttatgctccttgccggaagatgagtttattttcccgttg
agtatgccggctggtttgccaccggaagatcaaatcaaagtggcacaactggaaaatccg
gcagatgtggcttatcgcgagcatttagtggcatcttatggcaaaaacaaacaaatggtc
agcggcattcactataatttccaactcgaaccaacctttattcaacagcttttcgcacaa
caaaatacatatcaaagtgcggttgattttcaaaatgatttatatttaaaagttgcccgt
aatttcttgcgttatcaatggattctcgtttatttattagcagcgacgccaaccgttgac
gccaattattttcgtcacggcacaccgttaaaagcggggcaatatgtacgtagtttgcga
tccagtcaatatggttacgtgaatgacccgagtgtcaaagtgtcttatgacagcctgaac
gattatgtgaaaaccttagaacacgcggtcagtagtggacagcttattgccgaaaaagaa
ttttattccaacgtgcgtttacgtggtgcgaaacatgcccgcgaattgctacaaaacggc
attcaatatttggaattccgtctgttcgatctaaacccttttgaggcttatggtatcgca
ttaaatgacgccaaattcgtgcattattttattttattaatggcgtggttggatgaagaa
tctttggcaagtgcggtggatttaggcaaagaaaaattagcccaagtagcgtgggaaaat
ccgctgtcggcaacggctttccaagcggaaggggagcgcattttacagcaattgctggcg
atgttgacggaaattaatgctgacgtggaaattgaagcgatcgtcaaagataaattggtt
cagttcgctgaaccgagccaaaccctcggggcacgcttagtcaaggctattgaagcacat
ggtggctatcaaaaactgggcgcggaactggcgattcgctacaagcaacgggcgtttgaa
cgtttttatgctttgtctgctttcgacaacatggagctttccacccaagccctgatgttt
gatgccattcaaaaaggtctgaaaatggagattttagacgagcgggatcagttcttaagt
ctgcaattcggcgaccacttggaatatgtgaaaaacggcaacatgacctcccacgacagc
tacatttcgccactcatcatggaaaataaagtggtgaccaaaaaagtcttggcgaaagcc
ggctttaacgtgccgcaaagcgtggaatttactagcgttgaacaagccgtggccaattac
gctttatttgcaggacgtgccgtagtgattaaaccgaaatccaccaattacggtttgggc
atcagtattttccaacagggtgtgcatgatcgtgaggattttgccaaagctattgaaatt
gctttccgtgaagataaagaagtgatggtggaagattacctcactggcacggaatatcgt
ttcttcgtgctaggtgatgaaacgcttgctgtgttgttacgcgtgccggcgaatgtgatt
ggcgacagcgtgcatacggtagcagaattggtggcgcagaaaaacgatcatccgttgcgt
ggcgatggaagccgtacgccattgaagaaaattgcgttgggtgatatcgaacagttacag
ttaaaagagcagggcttaaccgttgatagcgtaccggcgaaagatcaattggtgcagctg
cgtgccaattctaacatcagtactggtggcgattccattgacatgaccgaccaaatgcac
ccaagctacaaagctttggcggttggtatcaccaaagccatgggtgctgctgtgtgtggc
gtggatttaatcattcccgatttaaccaagcccgccgagccgagcctgcaatcttggggc
gtgattgaagctaactttaatccaatgatgatgatgcacatcttcccgtacgcaggacaa
tcccgtcgggtgacgcaaaatgtgctgaagatgcttttcccggagctgaaataa
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