Arsenophonus apicola aApi_AU: QG404_04915
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Entry
QG404_04915 CDS
T09031
Symbol
murF
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
aapc
Arsenophonus apicola aApi_AU
Pathway
aapc00300
Lysine biosynthesis
aapc00550
Peptidoglycan biosynthesis
aapc01100
Metabolic pathways
aapc01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
aapc00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
QG404_04915 (murF)
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
QG404_04915 (murF)
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
QG404_04915 (murF)
Enzymes [BR:
aapc01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
QG404_04915 (murF)
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Paralog
Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
LpxD
Sm_multidrug_ex
Motif
Other DBs
NCBI-ProteinID:
WGO84236
UniProt:
A0ABY8P5J4
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Position
842658..844040
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AA seq
460 aa
AA seq
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MIPISLKHLATVTQGALQQINDRQAASLWLNAVTTNSRQRPIDGLFIALKGEHFDGHHFA
KEATEAGASALLVERPLTLHCPQVVVEDTRLAMGKLAAWVRSQSKAKVIGLTGSSGKTSV
KEMVAAILSQCGETLFTEGNLNNDIGVPLTLFRLTAEHQYAVIEMGANHIGEIAYTTNMI
RPDSVLVNNLFAAHLEGFGSLAGVAKAKGEIFQGLAEQGTAVINLASHDWKNWQLSFKQQ
QTIWRFSLTKQQQADFYAENITTKSTGSEFELHTPTGVISIFLPLPGTHNIANALAASAL
AMSVGATFEQVSLGLAHIQPVTGRLYPIHLAPGKLILDDTYNANTGSMIAAADVLSQMPG
YRILVVGDMGELGDKTEKCHQEVGEAARQMKLDRVLSVGQQSVIISQHSGCGEHFATKKE
LIAKLIPLIKEHETVSVLVKGSRSTAMEEVVHALQECFLC
NT seq
1383 nt
NT seq
+upstream
nt +downstream
nt
atgatccctatttcattgaagcatttggctactgtgacacaaggtgccctgcaacaaata
aatgatcgacaggcagccagtttgtggcttaatgcggtaacaacgaatagtcgccagcga
cccattgatggtctgtttattgctttaaagggtgaacattttgatggtcatcattttgct
aaagaggctactgaagcgggtgctagcgcattattagttgagcgaccattaactctacat
tgtccgcaagttgttgttgaagatacgcgtctagcaatgggaaagttagctgcttgggtt
agatcgcaaagtaaagctaaggttattgggctaacgggttcttctggcaaaacctcggtt
aaagagatggtggccgccattctctctcaatgcggcgagacactttttactgaaggtaat
ttgaataatgatattggtgtgcccttaacgttatttcgtttaacggcagagcaccagtat
gcagtgattgaaatgggagccaatcatattggtgaaattgcatatacaactaatatgatt
agaccggatagcgtattagtcaataatttatttgctgcccatcttgaaggttttggttca
cttgccggtgttgctaaagcaaagggcgagatttttcagggattagcagaacaaggaacg
gcggttattaatttggctagccatgattggaaaaattggcaattgtcttttaagcaacaa
caaaccatttggcgtttttcgctaacaaaacagcaacaggctgatttttatgcggaaaat
attaccactaaatcaacaggtagcgaatttgagctgcatacaccaactggtgtgatctca
atatttttacccttgccaggtacacataatattgccaatgcattagcggcgagtgcatta
gcaatgtccgtgggggcaacgtttgagcaagttagtcttggattggcacatattcagcca
gtaacaggacgtttatatccgattcatctagcgcccggtaaacttatcttagatgacact
tacaatgctaataccggctctatgattgctgccgccgatgttttatcccaaatgcccggc
taccgtattttggtcgttggtgatatgggggaattaggcgataagactgaaaaatgtcat
caggaggtcggtgaggcggctcgccaaatgaagcttgatcgagtgttaagtgtcggtcaa
caaagtgtcattattagccaacacagtggttgtggtgagcattttgctactaaaaaagag
ttaattgcgaaactgatcccattaataaaagaacacgaaaccgtatcagttttagttaaa
ggttcgcgcagtacagcaatggaagaagttgtacacgccttacaggagtgctttttatgt
tag
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