Amedibacterium intestinale JCM 30884: Aargi30884_01280
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Entry
Aargi30884_01280 CDS
T06426
Symbol
murF
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
aarg
Amedibacterium intestinale JCM 30884
Pathway
aarg00300
Lysine biosynthesis
aarg00550
Peptidoglycan biosynthesis
aarg01100
Metabolic pathways
aarg01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
aarg00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
Aargi30884_01280 (murF)
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
Aargi30884_01280 (murF)
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
Aargi30884_01280 (murF)
Enzymes [BR:
aarg01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
Aargi30884_01280 (murF)
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
VMAP-C
Motif
Other DBs
NCBI-ProteinID:
BBK21225
UniProt:
A0A6N4TFJ4
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Position
126720..128114
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AA seq
464 aa
AA seq
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MIIRSIDAIIRMLDADYIENGNIEEKIKGVCIDSRKVVEGNLYIPIHGINNNGHLFVQQA
IDNGAKAVLWERKEENPPEDVVVILVDDTTKALQELAKAYRKQLHMKVVGVTGSNGKTST
KDILASVLKEHYITQKTLGNYNNEIGVPLTLLSLNEDVEVAVVEMGMENLGELSFLTHLV
EPDIAIISNVGTAHLENLGTMENIAKAKVEIVEGLNENGSLIYNGDQELLKNAVREKEIP
GSISIRTFGMDKRNDYIVSAVRQKKEGIYFSVTPSEQSSYFLDMIGKHQAMNATAAMIAA
KALHVSDEEIQRGFTNIEKTGLRNELVVCDRCLILNDSYKSNPQSAIAALETMEEFEVPY
KIAVLGDMLELGETSDQIHYDLGKETARFHLQEILTIGDMARYIAQGAFNHNTDDVKVVY
FENKEELSEYLFPYMHKDCMLLVKGSRGMKLDELVNVLIEKNKK
NT seq
1395 nt
NT seq
+upstream
nt +downstream
nt
atgattattcgctcaatagatgctattattcgcatgcttgatgctgattatatagaaaat
ggaaatatcgaagaaaaaattaaaggagtatgtatcgactctcgtaaagttgtagaaggg
aacctatatattcctattcatggtattaacaacaatggacatctgtttgtccaacaggca
atagacaatggggctaaagctgttttatgggaaagaaaagaggaaaatccaccagaagat
gttgtagttattttagtggatgatacaacaaaagctctgcaggagctggcaaaagcttat
cgtaaacaattacatatgaaggttgttggggttacaggaagtaatgggaagacaagtaca
aaagatattcttgcctctgttttgaaagaacattacatcacacagaaaacattaggaaac
tataataatgaaattggtgttcctttaactttgttaagtcttaatgaagatgtagaagtt
gctgttgtagaaatgggaatggaaaatcttggagaattatcttttttgactcacttggta
gaaccagatattgcaatcatatcaaatgtaggaacagcacatttagaaaatctaggcaca
atggaaaatatcgcaaaagcaaaagttgaaattgtggaaggactaaatgagaatggatcg
cttatttataatggtgatcaggagttattaaaaaatgctgtacgagaaaaagaaattcct
ggttctatttccatacgtacatttggaatggacaagcgaaatgattacatcgtatctgca
gtacgtcagaaaaaagagggaatatactttagcgttacaccttctgaacaatcatcttat
tttttagatatgattgggaaacatcaggccatgaatgcgacggcagctatgattgcagcg
aaagcattgcatgtaagtgatgaagaaattcaaagaggttttacaaatattgaaaagaca
ggcttaagaaatgaattggttgtttgtgatcgctgtttgattttaaatgattcttataag
tctaatccacaaagtgcaattgctgcacttgaaactatggaagagtttgaagttccatat
aagattgctgttttaggagatatgctggaacttggagaaacaagtgatcagattcattat
gatttaggaaaagaaacagcaagatttcatttacaggaaattttaacaattggggatatg
gcacgatatattgcccagggagcttttaatcataatacagatgatgtgaaagttgtgtat
tttgaaaataaagaagaactttcagaatatcttttcccatacatgcataaagactgtatg
cttttggtgaagggttcccgtggtatgaagctagatgaattagtaaatgtattaatagaa
aaaaataagaaataa
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