Aggregatibacter actinomycetemcomitans D11S-1: D11S_2039
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Entry
D11S_2039 CDS
T00993
Name
(GenBank) bifunctional glutamate--cysteine ligase/glutathione synthetase
KO
K01919
glutamate--cysteine ligase [EC:
6.3.2.2
]
Organism
aat
Aggregatibacter actinomycetemcomitans D11S-1
Pathway
aat00270
Cysteine and methionine metabolism
aat00480
Glutathione metabolism
aat01100
Metabolic pathways
aat01240
Biosynthesis of cofactors
Brite
KEGG Orthology (KO) [BR:
aat00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
D11S_2039
09106 Metabolism of other amino acids
00480 Glutathione metabolism
D11S_2039
Enzymes [BR:
aat01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.2 glutamate---cysteine ligase
D11S_2039
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GFIT
Motif
Pfam:
Glu_cys_ligase
ATP-grasp_6
ATP-grasp_3
RimK
ATPgrasp_ST
Dala_Dala_lig_C
GARS_A
ATP-grasp
Motif
Other DBs
NCBI-ProteinID:
ACX83393
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Position
complement(1959365..1961638)
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AA seq
757 aa
AA seq
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MKIQQVIKENRLELLFQQGSFGIEKESQRVHADGSVVVSAHPKCFGSRSYHPYIQTDFAE
SQLELITPPNKKIEDTLRWLSAIHEVVLRTMLQDEYVFPLSMPAGLPPEDQIKVAQLENP
ADVAYREHLVQSYGKSKQMVSGVHYNFQLDPALIRQLFNGQNEYQSAVDFQNDLYLKVAR
NFLRYQWILVYLLAATPTVDANYFRGGTPLKPGQYVRSLRSSQYGYVNDPRVKISYDSLK
DYVNTLEHAVNSGQLIAEKEFYSNVRLRGAKHARELLQNGIQYLEFRLFDLNPFEPYGIA
LNDAKFVHYFILLMAWLDEESTESAVDLGKEKLAQVAWENPLSPTAFQSEGERVLQQLLA
MLTEIHAGAEIATIVKEKLAQFADPTLTLGARLVNAIEQHGGYQKLGAELAIRYKQQAFE
RFYALSAFDNMELSTQALMFDAIQKGLKIEILDERDQFLSLQFGDHLEYVKNGNMTSHDS
YISPLIMENKVVTKKVLAKAGFNVPQSVEFTSVEQAVANYALFAGRAVVIKPKSTNYGLG
ISIFQQGVHDREDFAKAIEIAFREDKEVMVEDYLTGTEYRFFVLGDETLAVLLRVPANVI
GDGVHTVAELVAQKNDHPLRGGGSRTPLKKIALGDIERLQLKEQGLAVDSVPVKDQLVQL
RANSNISTGGDSIDMTDQMHPSYKELAVGITKAMGAAVCGVDLIIPDLTKPAEPNLQSWG
VIEANFNPMMMMHIFPYAGQSRRVTQNVLKMLFPELK
NT seq
2274 nt
NT seq
+upstream
nt +downstream
nt
atgaaaattcagcaggttataaaagagaatcgcttggaattgttgtttcagcagggttct
ttcggtattgaaaaagaaagccaacgcgtgcatgcggacggttccgttgtggtaagcgca
cacccgaaatgttttggcagccgttcttaccacccttatatccaaacggatttcgccgaa
agccagcttgaattaattaccccgccgaataaaaaaattgaagacactttacgttggtta
tccgccattcatgaagtagtgttgcgcaccatgctgcaagatgaatacgtgtttccgtta
agtatgccggcagggttgccgccggaagatcaaatcaaagtagcgcaattggagaatccg
gcagatgtggcatatcgtgagcatttggtgcaatcctacggcaaaagcaaacaaatggtg
agcggtgttcactataatttccaactggatcccgctctaatccggcagctttttaacggg
caaaatgaataccaaagtgcggtggattttcagaatgatttgtatctgaaagttgcccga
aatttcctgcgttatcaatggattctcgtttatttactggcggcgacgccgaccgttgac
gctaattatttccgcggcggcacgccattaaaaccgggacaatatgtgcgtagtctgcgt
tccagccaatatggctatgtgaatgatccgagagtcaaaatttcttacgacagcttgaag
gattatgtcaatactttggaacacgcagtgaatagcggtcaattaatcgcggaaaaagag
ttttattccaatgtccgtttacgtggcgcgaagcacgcccgcgagctgctgcaaaacggc
attcagtatttggaatttcgcctgttcgatttgaatccgttcgagccttatggtattgcg
ctaaacgatgcgaaattcgttcactattttattttgcttatggcgtggttggacgaagaa
tccaccgaaagtgcggtggatttaggcaaagaaaaattagcgcaggtggcgtgggaaaat
ccgttgtcgccgaccgcctttcaatcggaaggggagcgtgtgttgcagcaattgctagcc
atgttgacggaaattcatgccggcgcggaaatcgcgacgatcgtaaaagagaaattggca
caatttgcggatccgacacttactcttggcgcgcgtttggttaatgctattgagcaacat
ggcggttatcaaaaattgggtgcggaactggcgattcgttacaaacagcaggcatttgag
cgtttttacgctttgtccgcttttgataatatggagctttccactcaagctctgatgttc
gatgcgattcaaaaagggctgaaaattgaaattctggatgagcgggatcaattcctcagc
ctgcaattcggcgatcatttggaatatgtgaaaaacggcaacatgacttcccacgacagc
tacatttcgccactgatcatggaaaataaagtggtgaccaaaaaagtgttggcgaaagcc
gggtttaacgtgccgcaaagtgtagaattcaccagtgtggaacaggcggttgccaattac
gccttatttgccggtcgtgccgtggtgattaaaccgaaatccaccaattacggcttaggt
atcagcattttccaacaaggtgtacatgatcgggaagattttgccaaagccattgaaatc
gcttttcgtgaagataaagaagtgatggtggaagattatttaaccggcaccgaataccgt
ttctttgtgctgggcgatgaaaccctggcggtgttattgcgcgtgccggcgaatgttatc
ggcgacggcgtgcatacggtggcggaattggtggcgcagaaaaacgatcatccgttgcgt
ggcggcggtagccgtacgccgttgaagaaaatcgctttgggcgatattgagcggttacag
ttgaaagaacagggtttggcggtggacagtgtgccggtaaaagatcagctggtgcagtta
cgcgccaattccaatatcagcaccggcggcgattccatcgatatgacagatcaaatgcac
ccaagctataaggaactcgcggtgggcattaccaaagccatgggcgcggcagtgtgcggc
gtggatttaattattcctgatttaaccaaacccgccgaaccgaacttacaatcctggggt
gtgattgaagccaatttcaacccgatgatgatgatgcacattttcccttacgccggacaa
tcccgcagagtgacacaaaacgtgttgaagatgttatttcctgagttgaagtaa
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