Aggregatibacter aphrophilus W10433: ADJ80_05525
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Entry
ADJ80_05525 CDS
T04521
Symbol
murF
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
aaz
Aggregatibacter aphrophilus W10433
Pathway
aaz00300
Lysine biosynthesis
aaz00550
Peptidoglycan biosynthesis
aaz01100
Metabolic pathways
aaz01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
aaz00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
ADJ80_05525 (murF)
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
ADJ80_05525 (murF)
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
ADJ80_05525 (murF)
Enzymes [BR:
aaz01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
ADJ80_05525 (murF)
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Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
Motif
Other DBs
NCBI-ProteinID:
AKU63253
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Position
1123280..1124659
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AA seq
459 aa
AA seq
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MITLSLSQLASILDAQLLGDGALTVENVSTDSRQSISKGLFFALKGEHFDAHHYLDKAAE
QGCIAAVVERQTNASIAQLVVKDTRLALGQLAKWLREKINPKTVAMTGSSGKTTVKEMTA
AILQQSAVDFDDVLFTHGNFNNDIGVPLTLLRLTQQHKFAVIELGANHIGEIAYTTALAQ
PDVALVNNVAAAHLEGFGSLDGVATAKGEIYRGLTSNGTAIINLAHNYQQKWQAEIGDHS
VQYFAYDNPQADYYAENIVFSEQGASFLLHTPKGSIQIHSSYLGEHNVSNALAATALAMN
VGASLQDVQNGLAMKSQVKGRLFPIEPCENLLLLDDTYNANVGSMKSAISVLQKYPAFRV
FVVGDMAELGDNTQLCHQEVADFAHAAKLDLVLSCGHASEVISAVNSGKHFTDKTELANY
LISVIKQQVTEQKVVVLVKGSRSMKMENVIDLLKDSFLC
NT seq
1380 nt
NT seq
+upstream
nt +downstream
nt
atgattacattatctctttctcaacttgcttctattttagatgctcaattacttggcgac
ggcgcactgacggtagaaaacgtcagcactgacagccgccaatccatctcgaaaggttta
ttctttgccttaaaaggcgaacattttgatgcccatcattatttagataaagctgctgaa
caaggttgtattgccgccgtagtggaacgccaaacaaacgcttcgatcgcgcagttagtg
gtaaaagacacccgcttggcgctcggacaactggctaaatggttacgcgaaaagattaat
ccgaaaactgttgctatgacaggctcttccggcaagaccactgtaaaagaaatgacagcc
gccattttgcagcaaagtgcggtggattttgacgatgttttatttacccacggcaacttc
aacaatgacatcggcgtgccgctcacattattacgcttaacacaacaacataaatttgct
gtcattgaacttggcgcgaatcatatcggtgaaattgcttataccaccgccttggcgcaa
cctgatgtcgcgttggtgaataacgtggcggcggcacatttggaaggatttggttctctt
gatggcgtagcaaccgccaaaggcgaaatttaccgtggactaacctcaaacggcactgca
attattaatctcgcccataattatcaacaaaaatggcaggcggaaatcggtgaccattcg
gtgcaatattttgcttacgataatccgcaagccgattattatgctgaaaacattgtattt
tctgagcagggtgcttcttttcttttacatacgccaaaaggcagtattcaaattcattct
tcttatttgggtgaacataatgtcagcaatgccttggcggcaactgcattggcaatgaat
gtcggtgcgagtttgcaggatgtacaaaacggcttggcgatgaaatcccaagtgaaaggg
cgcttgttcccaattgagccttgtgaaaatctcttactcttggatgatacctacaacgct
aacgtaggttccatgaaatccgctatttccgtgttgcaaaaatatccggcatttcgcgtc
tttgttgttggtgatatggcggaattgggcgataatacacagctttgtcaccaagaggtg
gccgattttgcgcacgccgccaaattagatttggtgctttcttgtggccatgcgtcggaa
gtgataagtgcggtcaattcgggcaaacattttacggataaaactgagttggcaaattat
ttaatctccgtaattaaacaacaagtaacagaacaaaaagtcgttgttttggtgaaagga
tcacgcagtatgaaaatggaaaacgtgatcgatttattgaaggatagtttcctatgttag
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