Acinetobacter baumannii AB5075-UW: ABUW_0285
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Entry
ABUW_0285 CDS
T11277
Symbol
murF
Name
(GenBank) UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate--D-alanyl-D-alanyl ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
aban Acinetobacter baumannii AB5075-UW
Pathway
aban00300
Lysine biosynthesis
aban00550
Peptidoglycan biosynthesis
aban01100
Metabolic pathways
aban01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
aban00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
ABUW_0285 (murF)
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
ABUW_0285 (murF)
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
ABUW_0285 (murF)
Enzymes [BR:
aban01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
ABUW_0285 (murF)
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
Motif
Other DBs
NCBI-ProteinID:
AKA30071
UniProt:
A0A0D5YEC3
Structure
PDB
PDBj
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Position
303349..304749
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AA seq
466 aa
AA seq
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MHTSTTSTVPLEPWTAQQLQQATQGYWHKDQIPQTEIKRILTDSRHAESGDAFLALKGER
FDAHNFVAQVVANGCQVAIVERPIDAEIAQLVVADTRLALGQLGAYRREQNAQLKVIALT
GSSGKTTTKEMLGSILSRLAPTLITRGNLNNDLGVPMMLLELRKEHQYAVMELGANHQGE
IDYTSKIVQPHVAGILNIGTAHLGEFGGRDGICRAKSEIYRHILPQGVAIVPQQDDFTAE
IREAAKSHQIMSFGAGGDVFATEIELLPQSANFQLHTPQGSSFVRLPFAGEHNVQNATAA
VAFALALGVSLEDIVKGLEQAQGAKGRLNFIQKTPHLFIDDTYNANPTSMRAAAQVLLQQ
NGIKVMVMGDIGELGDSSWQEHHDLGRDLAELPLDHIVAVGQFASAALEGAGLHSTKLKA
FQTQAEALPFLINLIQTHQPQSMSFLFKGSRFTHMETLMADLMEKL
NT seq
1401 nt
NT seq
+upstream
nt +downstream
nt
atgcatacttcaaccaccagtaccgtgcctttggaaccgtggacagctcaacaattacaa
caggcaacacagggttactggcataaagaccagatccctcaaactgaaattaaacgtatt
ttgactgactcgcgtcatgcagaaagtggggatgcctttttagcactaaaaggtgaacgt
ttcgacgcgcataattttgtcgcgcaagtggttgcaaatggttgccaagtcgctattgtc
gagcggcctatagatgcagaaattgctcagcttgtagttgccgatacccgtttggctttg
gggcagcttggtgcgtatcgtcgtgaacaaaatgctcaattgaaagtaattgctttaacg
ggcagtagtggtaaaaccaccaccaaagaaatgctaggaagtattttgtctcgtttagca
cctacattgattacccgaggcaatttaaataatgaccttggtgtgccgatgatgttgctt
gagcttcgaaaggagcatcagtatgcggtgatggaacttggtgcaaatcatcaaggtgaa
attgattacacatcaaaaattgttcaaccgcatgttgctggcattttaaatattggaact
gctcatttgggtgagttcggcgggcgtgatggcatttgccgcgctaaatcagaaatctat
cgccatattttacctcagggcgttgctattgttccgcaacaagatgactttaccgctgag
attcgtgaagcagccaaaagccatcaaatcatgagctttggtgctggtggtgatgtcttt
gctacagagattgaattgttgccacaatctgccaatttccagttacatacgcctcaaggt
tcaagttttgtaagactgccgtttgcgggtgagcacaatgtgcaaaacgcaactgcagca
gtagcatttgctttggcgttaggtgttagcttggaagatatcgtaaaaggtctagagcaa
gcacaaggtgcaaaaggtcgtttgaattttattcaaaaaacgcctcatttatttattgat
gatacttataacgccaatccaacatctatgcgtgctgcggcacaagtattacttcagcaa
aatggcattaaagtcatggtgatgggggatattggggagttaggtgatagcagttggcaa
gaacatcacgatttaggtcgcgatcttgctgagcttcctttagaccatattgttgcagtt
gggcagtttgcctcagcagctctcgaaggcgcaggtcttcattctactaaattgaaagca
tttcagactcaagctgaggcgcttccatttttaatcaatctaatccaaacacatcaaccc
cagtccatgagtttcctgtttaaaggttctcgctttactcatatggaaacgttgatggct
gatttgatggagaaactttaa
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