Amycolatopsis bartoniae: AMYBAR_001508
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Entry
AMYBAR_001508 CDS
T10755
Symbol
leuC
Name
(GenBank) 3-isopropylmalate dehydratase large subunit
KO
K01703
3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:
4.2.1.33
4.2.1.35
]
Organism
abar Amycolatopsis bartoniae
Pathway
abar00290
Valine, leucine and isoleucine biosynthesis
abar00660
C5-Branched dibasic acid metabolism
abar01100
Metabolic pathways
abar01110
Biosynthesis of secondary metabolites
abar01210
2-Oxocarboxylic acid metabolism
abar01230
Biosynthesis of amino acids
Module
abar_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
abar00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00660 C5-Branched dibasic acid metabolism
AMYBAR_001508 (leuC)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
AMYBAR_001508 (leuC)
Enzymes [BR:
abar01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.33 3-isopropylmalate dehydratase
AMYBAR_001508 (leuC)
4.2.1.35 (R)-2-methylmalate dehydratase
AMYBAR_001508 (leuC)
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Motif
Pfam:
Aconitase
AcnX
Motif
Other DBs
NCBI-ProteinID:
XMG32648
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Position
1550669..1552081
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AA seq
470 aa
AA seq
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MTDTRPRTLAEKVWDAHVVRKGEGAEPDLLYIDLHLVHEVTSPQAFDGLRLAGRPVRRPD
LTIATEDHNVPTVDIELPIADPVSRTQVDTLRRNCKEFGIRLHPMGDAEQGIVHVIGPQL
GLTQPGMTVVCGDSHTSTHGAFGAMAFGIGTSEVEHVLATQTLPLKPFKTMAINVDGELR
PGVTAKDIILAVIAKIGTGGGQGYVLEYRGSAIRSLSMEARMTICNMSIEAGARAGMIAP
DETTYAYLKDRPHAPKGADWDAAVANWNELRTDEGAEFDAEVHLDADSLTPFVTWGTNPG
QGLPLGESVPDPEAIADENERSAAEKALSYMDLKPGTPLREISVDTVFLGSCTNGRIEDL
RAAAGVLQGRKVAEGVRMLVVPGSMRVRQAAEAEGLDKVFVDAGAEWRQAGCSMCLGMNP
DQLKPGERSASTSNRNFEGRQGKGGRTHLVSPLVAAATAVRGTLSSPEDL
NT seq
1413 nt
NT seq
+upstream
nt +downstream
nt
atgaccgacacacggccccgcacgctggccgagaaggtctgggatgcgcacgtcgtgcgc
aagggcgaaggcgcggagcccgacctgctctacatcgacctgcacctggtgcacgaggtc
accagcccgcaggcgttcgacggcctgcggctggccgggcgcccggtgcgcaggcccgac
ctcaccatcgcgaccgaggaccacaacgtccccacggtcgacatcgagctgccgatcgcc
gacccggtgtcccgcacccaggtcgacacccttcgccgcaactgcaaggagttcggcatc
cggctgcacccgatgggcgacgccgagcagggcatcgtgcacgtcatcggcccgcagctc
ggcctgacgcagcccggcatgaccgtggtgtgcggcgacagccacacctccacgcacggc
gcgttcggcgcgatggcgttcggcatcggcacctccgaggtggagcacgtgctcgccacg
cagaccctgccgctgaagcccttcaagaccatggccatcaacgtggatggggagctgcgg
cccggcgtcacggcgaaggacatcatcctcgccgtcatcgcgaagatcggcaccggcggc
ggacagggctacgtgctggagtaccgcggcagcgcgatccgctcgctgtcgatggaagcc
cgcatgaccatctgcaacatgtccatcgaggcgggcgcccgcgccgggatgatcgcgccc
gacgagaccacctacgcctacctcaaggaccggccgcacgcccccaagggcgcggactgg
gacgccgcggtggcgaactggaacgagctgcgcaccgacgagggcgcggagttcgacgcc
gaggtgcacctcgacgccgacagcctgaccccgttcgtcacgtggggcaccaacccgggc
cagggtcttccgctgggtgaaagcgttcccgacccggaggccatcgcggacgagaacgag
cgctccgcggccgagaaggccctgtcctatatggacctgaagccgggcaccccgctgcgt
gagatcagcgtcgacacggtcttcctcggttcgtgcaccaacggccggatcgaggacctg
cgggccgcggcgggcgtgctgcagggccgcaaggtggccgagggcgtgcggatgctcgtc
gtgccgggctcgatgcgcgtgcggcaggcggccgaggccgaagggctggacaaggtgttc
gtcgacgccggtgccgagtggcgccaggcgggctgctcgatgtgcctgggcatgaacccg
gaccagctgaagccgggtgagcgcagcgcctccacctccaaccgcaacttcgagggcagg
cagggcaaggggggccgcacccacctcgtctcgccgctcgtcgcggccgccacggccgtc
cgcggcaccctgtccagccccgaggacctctga
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