Aeromonas bestiarum: IU367_06380
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Entry
IU367_06380 CDS
T08822
Symbol
thrA
Name
(GenBank) bifunctional aspartate kinase/homoserine dehydrogenase I
KO
K12524
bifunctional aspartokinase / homoserine dehydrogenase 1 [EC:
2.7.2.4
1.1.1.3
]
Organism
abes
Aeromonas bestiarum
Pathway
abes00260
Glycine, serine and threonine metabolism
abes00261
Monobactam biosynthesis
abes00270
Cysteine and methionine metabolism
abes00300
Lysine biosynthesis
abes01100
Metabolic pathways
abes01110
Biosynthesis of secondary metabolites
abes01120
Microbial metabolism in diverse environments
abes01230
Biosynthesis of amino acids
Module
abes_M00016
Lysine biosynthesis, succinyl-DAP pathway, aspartate => lysine
abes_M00017
Methionine biosynthesis, aspartate => homoserine => methionine
abes_M00018
Threonine biosynthesis, aspartate => homoserine => threonine
Brite
KEGG Orthology (KO) [BR:
abes00001
]
09100 Metabolism
09105 Amino acid metabolism
00260 Glycine, serine and threonine metabolism
IU367_06380 (thrA)
00270 Cysteine and methionine metabolism
IU367_06380 (thrA)
00300 Lysine biosynthesis
IU367_06380 (thrA)
09110 Biosynthesis of other secondary metabolites
00261 Monobactam biosynthesis
IU367_06380 (thrA)
Enzymes [BR:
abes01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.3 homoserine dehydrogenase
IU367_06380 (thrA)
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.2 Phosphotransferases with a carboxy group as acceptor
2.7.2.4 aspartate kinase
IU367_06380 (thrA)
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Gene cluster
GFIT
Motif
Pfam:
Homoserine_dh
ACT_9
AA_kinase
NAD_binding_3
ACT_7
ACT
Motif
Other DBs
NCBI-ProteinID:
WDL83813
LinkDB
All DBs
Position
1320162..1322621
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AA seq
819 aa
AA seq
DB search
MRVLKFGGSSLADAERFLRVADIAVNTHGQSQVALVLSAPAKVTNHLVALVEQTSRGMDA
SSTLFEINGIFSRLLAGLKAAYPALDDKALQARLTSELDQVERLMQGIRLLGLCPDNVQA
RILSRGENLSIAFMHELLRVRGLELDIIVPEQLLATDGGYLEAHVDIEASRLRFAAKGLR
SDCLYLMPGFTGGSDKGETVLLGRNGSDYSAAVLAACVDAECCEIWTDVEGCYNCDPRLV
PDAYLLKTLSYKEAMELSYFGAKVLHPKTIAPVAQFHIPCLIKNSFNPQGPGTLIGVEQG
DDDLKVKAISDLSGMCMFNVSGPGMKGMVGMAGRIFSAVSRAGVSIVLITQSSSEYSVSF
CIHSYDSDKTRKVLEREFELEFKNQLLDPLEIMSDLAIISLIGDGMRTSKGMAARFFTSL
AQASINIVAIAQGSSERSISAVVRDRKVAEAIKACHQNFFGSQQFIDLFVVGVGGVGAAL
VDQIARQQPVLAEQGTGLRVVGIANSRQMAVNKDGLNLANWREQLVEARDSFSLEAVQKL
VEESHLINPVIVDCTSSEAVAVQYADFLAAGFHVVTPNKKANTGSLDYYKALRRTARQTR
RKFLYETNVGAGLPVIENLQNLIKAGDKLRAFDGVLSGSLSFIFGKLDEGMAFSEATKIA
RGNGFTEPDPRDDLNGMDVARKLLILAREAGMALELSDVEVEQALPPGFDVSDDVEAFMA
RLPEADGWFRDQFAAAQSEGKVLRYVGSIEGGKCKVAIKAVGADEPLFKVKDGENALAFF
STYYQPIPLVLRGYGAGTEVTAAGVFADVLRTQNWKQEL
NT seq
2460 nt
NT seq
+upstream
nt +downstream
nt
atgagagtgttgaagtttggcgggtcgtcactggccgacgcagagcgttttttacgggta
gccgatatcgcggtcaatacccacggccaatcccaggttgccctggtgctgtcagcaccg
gccaaggtgaccaatcacctggtcgccctggtggagcagaccagtcgcggcatggatgcc
agttccaccctgtttgaaatcaacggcatcttctcccgcctgctggccggcttgaaggcg
gcctatccggcgctggatgacaaggcgctgcaggcgcgcctgaccagcgaactggatcag
gtggagcggctgatgcagggcatccgcctgctcgggctctgcccggacaacgtgcaggcc
cgcatcctgagccgcggcgagaacctctccatcgccttcatgcacgagttgctgcgagtg
cgcggcctcgagctggatatcatagtaccggagcaactgttggccaccgacggcggctac
ctggaagcccacgtcgacatcgaggcctcccgcctgcgcttcgccgccaagggcctgcgt
tccgattgcctctacctgatgccgggcttcaccggtggcagcgacaagggcgaaaccgtg
ttgctgggccgcaatgggtcggattactccgccgccgtgctggccgcctgcgtcgatgcc
gagtgctgcgagatctggaccgacgtggaaggttgctacaattgcgacccgcgcctggtg
ccggatgcctacctgctgaaaaccctctcctataaagaggcgatggagctctcgtatttt
ggcgccaaggtgctgcacccgaaaaccatagcccccgtggcccagttccacattccctgc
ctcatcaagaacagcttcaacccgcaggggccgggcaccttgattggcgtcgagcagggg
gatgacgacctgaaggtgaaagccatctcggatctctccggcatgtgcatgttcaacgtc
tccggccccggcatgaagggcatggtcggcatggccggccgcatcttctccgccgtctcc
cgcgccggggtcagtatcgtcctcatcacccagtcatcctccgagtacagcgtcagcttc
tgtatccacagctatgacagcgacaagacccgcaaggtgctggagcgcgagttcgagctg
gagttcaagaaccagctgctggatccgctggagatcatgagcgatctcgccatcatctcc
ctgatcggtgacggcatgcgcaccagcaaggggatggcggcgcgcttcttcacctcgctg
gcgcaggcctccatcaacatcgtcgccatcgcacaagggtcgagcgagcgctccatctcc
gccgtggtgcgggatcgcaaggtggcggaagccatcaaggcctgccaccagaacttcttc
ggcagtcagcagttcatcgacctcttcgtggtcggtgtcggcggcgtcggcgcggccctg
gtggatcagatagcccgccagcaacccgtgctggccgagcagggcactggcctgcgggtg
gtcggcatcgccaacagccgtcagatggcggtcaacaaggatgggctgaacctcgccaac
tggcgtgaacagctggtggaggcccgtgacagcttcagtctggaagcggtgcaaaagctg
gtggaagagagccacctcatcaacccggtgatcgtggattgcacctcctctgaggccgtc
gccgtccagtacgctgacttcctggccgccggtttccacgtggtcaccccgaacaagaag
gccaataccgggtcgctcgattactacaaggcgctacgtcgcaccgctcgccagactcgc
cgcaagttcctgtacgagaccaacgtcggcgccggcctgccggtcatcgagaacctgcaa
aacctcatcaaggccggcgacaagctgcgcgccttcgacggcgtgctgtccggttcgctc
tcctttatcttcggcaagctggacgagggtatggctttctccgaggcgaccaagattgcc
cgcggcaacggcttcaccgagccggatccccgcgacgatctcaacggcatggatgtggcg
cgcaagctgctgatcttggcccgcgaggccggtatggcgctggagctctccgatgtcgag
gtagagcaggcactgccgccgggctttgatgtgagcgacgatgtggaagccttcatggcc
cgcctgccggaagctgacggctggttccgcgaccagttcgcggcagcccagagcgagggc
aaggtgctgcgctacgtgggctccatcgagggtggcaagtgcaaggtcgccatcaaggcg
gtcggcgccgacgagccgctgttcaaggtaaaagacggggagaacgcgctcgccttcttc
tccacctactaccagccgatcccgctggtgctgcgcggctatggcgccggtaccgaagtg
actgccgctggcgtcttcgccgacgtgctgcgcacccagaactggaagcaggagttgtaa
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