Malaciobacter canalis: ACAN_0618
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Entry
ACAN_0618 CDS
T06502
Symbol
leuA
Name
(GenBank) 2-isopropylmalate synthase, bacterial type
KO
K01649
2-isopropylmalate synthase [EC:
2.3.3.13
]
Organism
acaa
Malaciobacter canalis
Pathway
acaa00290
Valine, leucine and isoleucine biosynthesis
acaa00620
Pyruvate metabolism
acaa01100
Metabolic pathways
acaa01110
Biosynthesis of secondary metabolites
acaa01210
2-Oxocarboxylic acid metabolism
acaa01230
Biosynthesis of amino acids
Module
acaa_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
acaa00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
ACAN_0618 (leuA)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
ACAN_0618 (leuA)
Enzymes [BR:
acaa01000
]
2. Transferases
2.3 Acyltransferases
2.3.3 Acyl groups converted into alkyl groups on transfer
2.3.3.13 2-isopropylmalate synthase
ACAN_0618 (leuA)
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GFIT
Motif
Pfam:
HMGL-like
LeuA_dimer
HCS_D2
NADH_4Fe-4S
IPMS_D2
EFhand_Ca_insen
Motif
Other DBs
NCBI-ProteinID:
QEE32122
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All DBs
Position
627808..629361
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AA seq
517 aa
AA seq
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MDNNKIVVFDTTLRDGEQSPGCSMNTEEKIKVAKQLEKLGVDVIEAGFAAASPGDFDAVS
RIAEQIEKSSICSLSRAVENDIKQAALAVQKAKMHRIHTFIATSPIHMKYKLKMSEEEVI
KRAVYAVEYARTFVDDVEFSLEDAGRSEISFMKEVMDAVIAAGATTINLPDTVGYRLPTE
LGAMVKELSDFAANRAIISVHNHNDLGLATANTLAAVTNGARQIEVTMNGLGERAGNSAL
EESVMAIKTRRDAFKDLYTNINTKEIYATSRLVATITGVEPQQNKAIVGKNAFAHESGIH
QDGVLKHQETYEIMRPEDVGVIKDSTLILGKHSGRAAFKDKITNLGFDTVTSEELNSAFE
KFKILADKKKEVTDDDIRMLITDESLNQDKIYELVGLQISDCSNGVPTAAVSIKHNDEIL
TDANIGNGTMDAIFKTIDRLTGYSGELQSYNVTSVTEGKDALAKVTTRVVFDEKSPSFVG
HGLSVDTMLATANAYVSALNSYLSQKERLAKNSEHQV
NT seq
1554 nt
NT seq
+upstream
nt +downstream
nt
atggataataataaaatagttgtatttgatacaacattaagggatggggagcaaagtcct
gggtgttctatgaacacagaagagaagattaaagttgctaagcaattagaaaaattaggt
gttgatgtaattgaagcaggttttgcagctgctagtccaggggactttgatgctgttagt
agaattgctgaacagattgaaaagtcttcaatctgttctttaagtagagctgttgaaaat
gatattaaacaagctgctttagcagtacaaaaagcaaagatgcatagaattcatacattt
attgcaacttctcctattcatatgaaatataaattgaaaatgagtgaagaagaagtaata
aaaagagcagtatatgcagttgaatatgcaagaacttttgttgatgatgttgagttttct
ttagaagatgcaggaagaagtgaaatctcttttatgaaagaggtaatggatgcagttatt
gctgctggagctacaactattaatttacctgatactgttggatatagattaccaacagaa
ttgggagcaatggttaaagagttatctgattttgcagctaatagagcaataatctctgtt
cataatcacaatgatttaggtttagcaacagcaaacactttagcagctgtaacaaatggt
gctagacaaattgaagtaactatgaatggtttaggagaaagagctggtaattctgcttta
gaagaatcagttatggctattaaaacaagacgtgatgcttttaaggatttatatacaaat
ataaatacaaaagagatttatgcaacttcgagattagttgcaactattacaggtgttgag
ccacaacaaaacaaagcaattgttggtaaaaatgcatttgctcatgaaagtggaattcat
caagatggtgtattaaaacatcaagaaacatatgaaattatgagacctgaagatgttggt
gttattaaagattctactttaattttaggaaaacattcaggacgtgctgcatttaaagat
aaaataactaacttaggttttgatacagtaacaagtgaagagttaaattcagcctttgaa
aaatttaaaatcttagcagataagaaaaaagaagtaactgatgatgatattagaatgtta
attactgatgagtcattaaatcaagataaaatctatgagttagttggattacaaatttct
gattgttcaaatggagtaccaacagcagctgtttctattaaacataatgatgaaatttta
acagatgcaaatattggtaatggaacaatggatgcaatattcaaaacaattgatagactt
acaggctatagtggggagttacaaagttataatgtgacttctgttacagaaggaaaagat
gccttagcaaaagttacaacaagagtagtttttgatgaaaaatctccatcatttgtaggt
catggtttaagtgttgatacaatgcttgcaactgcaaatgcatatgttagtgcattaaac
tcatatctttcacaaaaagaaagacttgcaaaaaatagtgaacatcaagtatag
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