Amycolatopsis carbonis: QRX50_22305
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Entry
QRX50_22305 CDS
T10496
Name
(GenBank) folylpolyglutamate synthase/dihydrofolate synthase family protein
KO
K11754
dihydrofolate synthase / folylpolyglutamate synthase [EC:
6.3.2.12
6.3.2.17
]
Organism
acab Amycolatopsis carbonis
Pathway
acab00790
Folate biosynthesis
acab01100
Metabolic pathways
acab01240
Biosynthesis of cofactors
Module
acab_M00126
Tetrahydrofolate biosynthesis, GTP => THF
Brite
KEGG Orthology (KO) [BR:
acab00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
QRX50_22305
Enzymes [BR:
acab01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.12 dihydrofolate synthase
QRX50_22305
6.3.2.17 tetrahydrofolate synthase
QRX50_22305
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Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_C
Mur_ligase_M
Motif
Other DBs
NCBI-ProteinID:
WIX83992
UniProt:
A0A9Y2IPQ7
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Position
4505802..4507454
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AA seq
550 aa
AA seq
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MDEAGQRRPDLADPDSFAGVDELGARAHDESDDIDPDLDAPDAAYTVGGGSRGGIGGIGQ
LGDNLATGPVPDLLGAEEAELHELDDQGVEEPAQNPNGPQARRELMAVEAELNQRWPETK
IEPSLARIQALVTLLGEPNRGYPVLHVAGTNGKGSVSRMIDALLTRMGLRVGRYTSPHLQ
LVTERIALDGHPISAARYVDLFRDVAPYVNMVDAASEDGVAMSKFEVLTGMAFAAFSDAP
VEAAVIEAGMGGAWDATNVADADVAVITPIGLDHTEYLGPTAVDAAREKAGIIKPGSVAV
IAEQDPDVLNVLLKRAVDVDAAVARAGSEFGVLEREVAVGGQMLKLQGLGGVYDQIFLPL
HGAHQAANAALALASVEAFFGAGKERQLVLEAVREAFAEVENPGRLERVRAAPTVLLDAA
HNPMGAQALATTVTDEFAFRRLVAVVAVMADKDARGILDALEPVVSDVVVTRNSAPRSME
LEDLNELAISIFGEDRVLAEPDLETAVETAIGLVEQSDDPEEPLAGGGVLVTGSVVTAGE
ARTLFGKEPV
NT seq
1653 nt
NT seq
+upstream
nt +downstream
nt
atcgacgaggccggccagaggcggcccgatctcgcggacccggacagtttcgccggggtc
gacgagctgggggcgcgggcgcacgacgaatcggacgacatcgaccccgacctggacgcg
ccggacgccgcgtacaccgtcggcggtgggtcccgcgggggtatcggcgggatcgggcag
ctgggggacaacctggcgaccggcccggtgccggacctgctcggagccgaagaggcggag
ctgcacgagctcgacgaccagggtgtcgaagagccggcgcagaaccccaacgggccccag
gcgcgccgggagctcatggccgtcgaggcggagctgaaccagcgctggcccgagacgaag
atcgagccgagcctcgcgcggatccaggcgctggtcacgctgctgggcgagccgaaccgc
ggctaccccgtgctgcacgtcgccggaaccaacggcaagggctcggtcagccgcatgatc
gacgcgctgctcacccgcatgggcctgcgcgtcgggcggtacacgagcccgcacctgcag
ctggtcaccgaacgcatcgcgctcgacgggcacccgatctcggccgcgcggtacgtggat
ctgttccgcgacgtcgcgccgtacgtgaacatggtggacgccgcaagcgaggacggcgtg
gcgatgagcaagttcgaggtgctcaccggcatggcgttcgccgcgttctccgacgcgccc
gtggaggccgccgtgatcgaggcgggcatgggcggggcgtgggatgccacgaacgtcgcc
gacgccgacgtcgccgtgatcacccccatcggcctcgaccacaccgagtacctcggcccg
acggccgtcgacgcggcgcgcgagaaggccgggatcatcaagcccggctccgtcgccgtg
atcgccgagcaggaccccgacgtgctcaacgtgctgctcaagcgcgcggtcgacgtcgac
gccgcggtggcgcgcgccggcagcgagttcggcgtgctggagcgcgaggtcgcggtcggc
gggcagatgctgaagctgcagggcctcggcggcgtgtacgaccagatcttcctgcccctg
cacggcgcccaccaggcggccaacgcggcgctcgcgctcgcgtccgtcgaggcgttcttc
ggtgcgggcaaggagcgccagctggtgctcgaagccgtgcgcgaggccttcgccgaggtc
gagaacccgggccggctggagcgcgtgcgcgccgcccccaccgtgctcctcgacgcggcg
cacaaccccatgggcgcgcaggcgctggccaccaccgtcaccgacgagttcgccttccgc
cgactggtcgccgtcgtcgcggtgatggcggacaaggacgcgcgcggcatcctcgacgcg
ctcgagccggtggtgtcggacgtcgtggtcacccgcaactcggccccgcggtcgatggaa
ctcgaggacctcaacgaactggccatctccatcttcggcgaggaccgcgtgctcgccgag
cccgacctggagacagccgtcgagacggccatcggcctcgtcgaacagtccgacgacccg
gaggaacccctcgccggcggcggcgtgctggtcaccggctccgtggtcaccgcgggcgag
gcccgcaccctcttcgggaaggaaccggtatga
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