Amycolatopsis carbonis: QRX50_37425
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Entry
QRX50_37425 CDS
T10496
Name
(GenBank) SDR family NAD(P)-dependent oxidoreductase
KO
K16386
polyene macrolide polyketide synthase
Organism
acab Amycolatopsis carbonis
Pathway
acab01052
Type I polyketide structures
Brite
Polyketide biosynthesis proteins [BR:
acab01008
]
Polyketide synthase (PKS)
Modular type I PKS
cis-AT PKS
Polyene macrolide PKS
QRX50_37425
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Other DBs
NCBI-ProteinID:
WIX84130
UniProt:
A0A9Y2MWP0
LinkDB
All DBs
Position
complement(7559845..7573884)
Genome browser
AA seq
4679 aa
AA seq
DB search
MRHGGLPRSLHADRPTTHVDWDSGAVRVLTEAVPWPETGRPRRAGVSAFGISGTNAHVIL
EQAPAEPDAVVRPDAVGPVPIVVSGQSEPALREQAARLGAFVADAPEMSWADLAWSLATA
RSAFDHRAVFVPADRAELVSSLAALAAGDQSGLVSGSAGRIALVFSGQGAQRVGMGRELS
ARFPVFAAALSDVCALLDPLLAGEHALREVMFAEAELLDRTGYTQPALFAWQTAWFRLLQ
SWGVRPDFLMGHSIGEIGAAHAAGVFSLEDACTLVAARANLMQALPSGGAMLAVSASESD
IVPLLGNYGDTVGIAAVNAGHAVVVSGDQDAIADLGRVLGERGHKTTWLRVSHAFHSALM
DPMLDGFRAAIGGMTFHEPAVPLVSHVTGDVAGAEVATVDYWVRHVREPVRFADGVATAA
SKGAAVFVEAGPASTLSSMIGAELDPEHTTVIPAVRKDQDEVTGAVAAVAQLHAVGADVD
WAAVFAGLNVEGRRVGLPTYAFQRERFWPGVVVSAAGVGAAGLDVVEHPLLGAGTPLPES
DGYVFSGRLSPATQPWLAEHATNGVVILPGTAFVEVVIRAGDAVGCGRIDDLTLHEPLVL
PEQDGVDLQVLVGGPEGDGVRPVTVYSRVASPDQPWTRHAVGTVTPTAGADAGWTDPAWP
PRDAVPVSLAGFYGHAGRSAFDYGPVFRGLQAVWTRGSEVFAEVVVPPTARELVNRFGLH
PALLDAALQANVFAPLAPAEHGRLPFSFSGVALHATGATTLRVRLTATGPDAVRIEAVDP
GGSPVVTVESLVLRPLVPELLTRAAASGAPEALLRLEWTPGPEVSAGTAGAWWVLDGYHG
EIGDLSNELGVASSLDELVGAGARNVVVPVGGSGGEVAEEVQAMTAAVLGLLQAWLARPE
LSEARLVFLTRNAVSTTEAQPVADLAAAAVWGLVRSAQTEHPDRFTLLDHDHQPLTRDQL
VTAEPQAAIRDHRTLVPRLTVPSGDELLAVPSGAEDAWRLEVSEKGTVDNLVLRAAPSLA
EPLGQGQVRVAVRVAGLNFRDVLNALGMYPGDPVPLGLEVAGVVTEVGPDVTDLTPGDRV
MGIAPGGFGPVAVTDRRSLVVIPRPWSFAQAATAPVVFLTACHGLRDLAGLRAGESVLIH
AGAGGVGMAAIQLARHLGAEVFATAAPAKWDVLRSLGLPDDHIASSRTVDFEERFSATTR
GRGVDVVLNSLTGEFVDASLRLLARGGRFVEMGKADLRDAREVAAAHPGVSYQAFDLMEV
DLDRIQRMLVELAALFASDALTTLPVTTWDVRRAPEAFRFVSQAKHVGKVALTIPRPPDP
RGTVVITGGTGGLGAVLARHLVERREARRLVLISRRGESAPGAAELGAELIGLGAEVTVA
ACDVADRDRLAEVLAAAQPVTAVVHTAGVLADATVESLTPEAVGRVFEPKVRGAWNLHEL
TRDTDLSAFVLFSSVGGVTGAAGQANYAAANAFLDALASVRHGQGRPAVSVAWGAWTPEA
GMTGALSEVDLERLTRSGMPPMTVDQGLALFDRAVAADRAMLVATRLDRKAAASQSSRLF
DALTTRPPARIGAASEGSEDSVLRRLSAMTSTDRTRALTDLVRTQVAAVLGHAVPSAIDP
AQAFKELGMDSLTSVELRNRVNKVFGTRLPATEIFNHPTTAQLTDRIAIELGLRQEEAAP
APAVTAADDDPIVIVGMGCRFPGGAGSPEDLWDLVVSGRDAISDFPADRGWDLAALRGGA
SATRQGGFLYEAPEFDADFFGISPREALAMDPQQRLLLEVSWEALERSGITPDSVGGTRT
GVFVGAYHQDYLREKTAARDELGGYLLTGTTSSVMSGRIAYSLGLEGPAVTVDTACSSSL
VALHWATQSLRSGECDLALVGGVTVMSTPDIFEEFSRQDGLSVDGRCKPFAESADGTGWS
EGVGVLVVQRLSSARAAGRRVLAVVRGSAVNQDGASNGLTAPNGPSQQRVIKDALARAGV
SAGEIDAVEAHGTGTRLGDPIEAQALLATLGQGREEDRPVWLGSVKSNIGHTQAAAGVAG
IIKMVQAMRHGILPRTLHVDEPTTHVDWAAGGVRVLTEQIPWPETGRPRRAGVSGFGISG
TNAHVILEQAPGEAERVTTVDTGAPVPVLVSGRSGSAVRDQAARLVSLLDRDRGLAVTDL
AWSLATTRSSFDHRAVVVAADRAELAPKLRALAAGEADPAVVTGVAASSGGVVFVFPGQG
SQWSGMGRELLETSPVFREWILKCQEALAPWVTWSLTEVLTGDHAELAERVDVVQPVLWA
MMVSLAELWRSYGIHPEAVVGHSQGEIAAACVAGALSLEDGARVVALRAQALREIAGQGG
MLSVALSQDEVRHWLARGDGRVSLAAINAAASVVLAGEATVLERLRSEMTEQGIRARRVE
VDYASHSPHVEQVRDRVLAALAPITPRTADVKFLSTVDSVWLDGTELDADYWYRNLRQTV
RFEPAVRTLLADGYQAFVETSAHPVITVPLSETVEDAGAHAVVTGTLRRDQGSLRRMLTS
LATLHTAGVKVDWTRVFGAEGRRVELPTYAFQHQRFWPASAPVEALSGWGYDVVWTPAPQ
PASPRTPGSWWLIAPAGYEESPLITGLRQELAGAGATADLVVVPAERTDRAALAARIGEL
AVPTGVVSFLAWHDIPVAQGSEVSLGLTLTATLLQALGDASIQAPVWSVTRGAVSVADLA
EVSHPAQTAVWGWGRTAAVEYPRRWGGLIDVPAGEPDAILTARLAQVLMSGGSTEDQLAI
RPSGTWARRLARRALTPADVPEWEVPVAGTVLVTGGTGALGGHVARWLATSGVPHLVLLS
RQGLQADGARDLEAELTGLGARVTVVACDAADREAMAEVIAGVPAEYPLAGVVHTAVVVD
DGIIETVTGEQLATVFRPKVDAAVVLHELTRDLDLAMFVMFSSISATLGGVGLSTYAAAN
AYLDGLAQYRRAQGLPATSIAWGTWAGDGLASATAAQQNLRRFGMITMAPAPALEGLRRV
LERGDATAVIADVDWKQYLSVFTAARPSALLGDLPETRQSTTDQDDSGAKLALDPAVRLR
TRLAGLAHADQVRVVLDLVRVQLAAILGYGDSDPIPENRAFRDLGFDSLTAVELRNILSM
ATGLDLPRTLVFDYPTPTDLARHLLDELSGDGADEPAALAPARVPSDDDPIVVVGMGCRF
PGGVSSPEDLWSLVASGGDAISEFPADRGWDLAGLRAGGSTTRLGGFLDEVAEFDAGFFG
ISPREALAMDPQQRLLLETAWEALERAGIKPASLRGTRTGVFVGSSIQDYIHASMQVRED
LEGYLLTGSSSSVLSGRVAYLLGLEGPAITVDTACSSSLVALHWAAQSLLSGECELALAG
GVTVMSTAELFLDFTRQGALSVDGRCKAFAETADGAGFSEGVGVLAVERLSSARAAGRRV
LAVVRGSAVNQDGASNGLTAPNGPSQQRVIKDALARAGVSAGEIDAVEAHGTGTRLGDPI
EAQALLATLGQGREEDRPVWLGSVKSNIGHTQAAAGVAGIIKMVQAMRHGILPRTLHVDE
PTTHVDWAAGGVRVLTEQIPWPETGRPRRAGVSGFGISGTNAHVVLEQAPEQPEVEPAGI
TAPVPLVLSGQSVPAVRGQAARLAELLDGDGDAALADVAWSAALTRSAFDHRAVVVAADR
QEALSSLRALAAGEPGPTAVTGEARVSGGVVFVFPGQGSQWAGMGRELLETSAVFRESIQ
ECQDALAPWISWSLTDVLDRADLLERVDVVQPALWAMNVSLAKLWRSHGVEPAAVIGHSQ
GEIAAACVAGALSLEDGARVVALRAQALRVLAGHGGMLSVALSQDDVREWLVRYDGQLSL
AAVNAPTSVVVAGDTAALAHLQNELTGHDIRARRIEVDYASHSPEVEQVRDQVLEKLAPI
TPRTPGVKFFSTVDEKWLDGTELDAGYWYRNLRRTVGFEPAVRALLADGYRAFIEVSPHP
VTTVPLTETAEAAGTPAVVTGTLRRDQGSRHRALTSLASLYAEGIDLDWAAVFAGIGAGG
RRVDLPTYAFQRRRYWPEITAHPVQGPRVEDLVLNLDWTTEPDPTGAGAAPRTWWLLDDH
HNGVSTLPGELGVSRVVDDLVELGKQLDTGDRAPDALLVPVHGPDGDVTAAVQATTVEVL
GLLQQWLAKTEFSGIRLVFLTRDAVSAESTTDLAAAAIWGLVKSAQAEHPGRFTLVDHDR
HPLSAGLLAEALATGEPQLAIRAHRVAVPRLAPAREQEPAAPVRWDQGTVVITGGTGGLG
AALARHLVAGGRANRLLLLNRRGHDAPGAAELRAELTGLGAEVTITACDIADRARLAEAL
DAVRPVSAVVHTAVVVADGTIESLTPEAVGRVFEPKVRGAWNLHELTQGDELSAFVLFSA
MAGVMGTPGQGNYAAANTFLDALARHRRAGGLPAVSMDWGTWTSDVGLASALSDTDLRRL
ARTGFPAMSIDNGLALFDRAMTVDEPIVAPVRLDRVAAAAQPSRLLEDLVVRRPEPAGTP
TEPETGPRLADRLATLTPTDRIRTMTDLVRGQVAAVLGHTTPDDVRPTQAFKDIGMDSLT
SIELRNRLNEATGLRLPTTIAFDNPNPEVLAGHLVAELIGTTTVAVAVTGSVTTQLDALE
TTFLTVALDATARPMLRKRLRALLGRIDEAPTTSESPQSSVDTASDEDLFAMLDDQLGH
NT seq
14040 nt
NT seq
+upstream
nt +downstream
nt
atgcggcacggtggtcttccgcgcagcctgcacgccgaccggcccaccacccacgtggat
tgggactccggtgcggtgcgggtactgaccgaggcggttccctggccggagaccggtcgg
ccgcgccgggcgggggtgtcggcgttcggcatcagcggcaccaacgctcacgtcatcctc
gaacaggcgcccgccgagcccgacgccgtggtgcggcctgacgcggtcggcccggtgccg
atcgtggtgtccggtcagtccgagccggcgctgcgcgagcaggcggcccggttgggcgcg
ttcgtcgcggacgctccggaaatgtcgtgggcggatctggcctggtccttggccaccgcg
cggtcggctttcgaccatcgggcggttttcgtgcccgccgatcgggccgagctggtgtcg
tcgttggccgctctggctgccggcgaccagtcgggcctcgtcagcggaagcgcgggtcgg
atcgcgctcgtcttttccgggcagggcgctcagcgggtggggatgggtcgtgagctttcg
gcccggttcccggttttcgccgcggcgctgagtgacgtttgtgcgttgctggatccgttg
ttggcgggcgaacacgcgttgcgtgaggtgatgttcgccgaggcggagttgctggatcgg
acgggttacacgcagcctgcgttgtttgcttggcagacggcgtggttccgcctgctgcag
tcgtggggtgttcgtcctgattttttgatggggcattcgatcggtgagatcggtgcggct
catgcggctggtgtgttttcgcttgaggacgcgtgcacgctggtcgcggcgcgggccaat
ctgatgcaggcgttgccgagtggcggagccatgctcgcggtcagcgcatcggagagcgac
atcgtgccgctgctcgggaactacggcgacaccgtgggtatcgcggccgtcaacgccggt
cacgcggtggtggtgtccggggatcaggacgcgatcgcggacctcggccgggtgctgggg
gagcggggacacaagaccacgtggttgcgggtgagtcacgcgttccattcggctctgatg
gatccgatgctggacgggttccgcgcggctatcggcgggatgacgttccacgagccggcc
gtcccgttggtgtcccacgtgaccggcgacgtggccggagccgaagtggccactgtggac
tattgggtccggcacgtccgggaaccggtccgcttcgccgacggagtggccacagcggcc
agtaagggcgccgccgtcttcgtggaggccgggccggcgagcacgctgtcgtcgatgatc
ggcgccgagctggaccccgagcacacgacggtgattcccgcggtccggaaggaccaggac
gaggtcacgggcgccgtcgccgccgtcgcgcagctgcacgcggtgggggccgacgtcgac
tgggccgcggtgttcgcggggctgaatgtcgaggggcgtcgggtcgggttgccgacgtat
gcgttccagcgtgagcggttctggcccggcgtggtggtgtccgcggccggcgtgggcgcg
gcggggctggatgtggtggagcatccgttgctgggtgcggggactccgttgcccgagtcg
gacggctacgtcttcagcggccggctctcgccggccacgcaaccctggctggccgagcac
gcgacgaacggtgtggtgatccttccggggaccgcgttcgtcgaggtggtcatccgggcg
ggggacgcggtcgggtgcggtcggatcgacgacctcaccctgcacgagccgcttgtgctg
cccgagcaggacggcgtcgatctgcaggtgctggtgggcgggcccgagggcgacggcgtc
cggccggtcacggtgtactcccgggtcgcctcgccggaccagccgtggacccggcacgcc
gtcggcacggtcacgcccacggcaggcgctgacgccggctggacggacccggcgtggcca
ccgcgagacgctgttccggtgtcgttggcaggcttctacggccacgccggccggtcggct
ttcgactacgggccggtgttccggggccttcaggcggtgtggacacgcgggagcgaggtg
ttcgccgaggtcgtggtgccgccgacggcgcgcgagttggtgaaccggttcggtctgcac
ccggcgctgctggacgcagcattgcaggccaatgtgttcgcgccgctcgctccggccgaa
cacggtcgcctgccgttctctttcagcggtgtcgctttgcacgccaccggtgcgaccacg
ctccgggtccggctgaccgcgaccggcccggacgccgtccgcatcgaagccgtcgatccc
ggtggctctccggtggtcaccgtcgaatcgctggtgctgcggccgcttgtgccggagctg
ctcacgcgggccgcggcatcgggcgcgccggaggcgttgcttcgtctcgagtggacaccc
gggccggaggtgagcgccggtaccgccggggcctggtgggtgctggacggctaccacggg
gagatcggcgatctctcgaacgagctgggtgtggcgagcagcttggacgagctcgtcggc
gccggtgcgcgaaacgtggtggtaccggtcggcggctcgggcggggaagtcgccgaagaa
gtccaggcgatgaccgccgcggtactcggcttgctgcaggcgtggctcgcccggccggag
ctgagcgaggcgcggctggtgttcctgacccgcaacgcggtgagcacgaccgaggcccag
ccggtcgcggatctcgccgccgccgcggtgtggggcttggtcaggtccgcgcagaccgaa
catcccgaccggttcacgctcctcgaccacgaccaccagcccctgacccgagatcagctc
gttaccgccgagccccaggccgccatccgtgaccaccggaccctggtccccaggctgacc
gtgccgtccggcgacgagctgctggcagtcccctcgggtgccgaggatgcgtggcgactg
gaggtgtccgagaagggcacggtggacaacctcgtcctgcgggcggcgccgtcactggcc
gaaccgctggggcaggggcaggtccgggtcgcggtgcgggtcgccgggctgaacttccgg
gacgtgctcaacgcgctcggcatgtatccgggcgatccggttccgctgggcctcgaggtc
gccggcgtggtcacggaggtgggcccggacgtcaccgacctgacccccggtgaccgggtc
atgggtatcgcgcccggtgggttcggcccggtggcggtgaccgaccggcggtcgctcgtc
gtgatccctcggccgtggtcgttcgcccaggcggcgacggcgccggtggtgttcctgacc
gcctgccacggcctgcgcgacctggccggactgcgggcgggcgaatcggtgctgatccac
gccggtgccggcggcgtcgggatggccgcgatccagctggcccggcacctcggcgccgag
gttttcgccaccgccgctccggccaagtgggacgtgctgcgttccctcggcctgccggac
gatcacatcgcctcgtcgcgcaccgtggacttcgaagagcgtttctcggcgacgacgcga
ggtcgtggtgtggatgtcgtcctgaactcgctgacaggggagttcgtggacgcgtcgctg
cggctgctcgcgcgcggtggccggttcgtggagatgggcaaggccgacctccgtgatgcg
cgagaggtcgccgcggctcatccgggcgtgtcctatcaggcgttcgacctgatggaggtc
gacctggaccggattcagcggatgctggtcgagctggccgcgttgttcgcgtcggatgcc
ttgaccacgttgccggtcacgacctgggacgtccggcgtgcgcccgaggcgttccggttc
gtcagccaggccaagcacgtcgggaaggtcgccctgacgatcccgcggccgccggacccc
cggggcacggtggtgatcacgggtgggaccggcgggttgggggccgtgctggctcggcac
ctcgtcgaacggcgtgaagcgcgcaggctggtgctgatcagcaggcgaggggagtcggcg
ccaggagccgcggagctcggcgccgagctgatcggcctgggcgccgaggtcacggtcgcg
gcgtgcgacgtcgcggaccgcgaccggctggccgaggtgctggccgcggcgcagccggtg
acggccgtggtgcacaccgcgggtgtcctggcggacgcgaccgtcgagtccttgacaccg
gaagcggtcggccgcgtgttcgagcccaaggtgcggggcgcgtggaacctgcacgagctc
acccgcgacaccgatctgtcggcgttcgtcttgttctcctccgtcggcggtgtcacgggc
gccgccggtcaagccaactacgccgcggcgaacgctttcctcgacgccctggcctcggtg
cggcacggacagggcaggccggcggtgtcggtggcgtggggtgcgtggaccccggaagcg
ggcatgaccggcgccctgtccgaagtggacctcgagcggctgacccgttcggggatgccg
ccgatgaccgtcgaccaggggctcgcgctgttcgaccgagccgtcgccgcggaccgggcg
atgctcgtcgcgacacggttggaccgcaaggcggcggcgtcccagtcctcccggttgttc
gacgccctcaccaccaggccaccggcccggatcggcgcggcctcggagggctcggaggac
tcggtgctccggcggctgtcggccatgacgtcgaccgaccggacgcgggccctcacggac
ctggtccgcacccaggtggccgccgtgctgggccacgcggtgccgagcgccatcgacccg
gcccaggcgttcaaggaactggggatggactccctgacttcggtcgagttgcgcaaccgg
gtgaacaaggtcttcgggacccggctgccggcgaccgagatcttcaaccacccgacgacg
gcccagctgaccgaccggatcgcgatcgaactcggtctccggcaggaggaagccgccccc
gccccggctgtcacggccgctgacgacgacccgatcgtcatcgtcgggatgggctgccgg
ttccccggcggggccggctcgccggaagacctgtgggacctggtcgtctccggccgggac
gcgatctccgatttcccggccgaccgtgggtgggatctggccgcgttgcgtggtggggcg
tcggcgacccggcagggcgggttcctctacgaggcacccgagttcgacgcggacttcttc
gggatctcgccccgcgaagcgctggccatggacccgcagcaacggctgctcctggaagtc
tcctgggaagccttggagcggtccgggatcactccggactcggttggtgggacccggacc
ggtgtgttcgtcggcgcctaccaccaggactacctccgcgagaagaccgcggccagggac
gagctcggcggctacctgctgaccggcaccacgtcgagcgtgatgtcgggccgcatcgcc
tactcgctcgggttggaaggcccggcggtgaccgtcgacacggcgtgttcgtcgtcgctg
gtggcgctgcactgggccacgcagtccctgcggtccggggagtgcgatctggcgctcgtc
ggcggtgtcaccgtgatgtccacaccggacatcttcgaggagttttcccgccaggacggg
ctgtcggtggacggccggtgcaaaccgttcgccgagtcggcggacggcaccgggtggagt
gagggcgtcggtgtcctcgtcgtgcaacggttgtcgtcggctcgggcggcgggtcgccgg
gtgctggcggtggtgcggggttcggcggtgaaccaggatggcgcgtcgaatgggttgacg
gcgccgaatggcccgtcgcagcagcgggtgatcaaggacgcgttggctcgggcgggggtg
tccgcgggggagatcgacgctgtggaggcgcacggcacgggtacgcggctgggtgatccc
atcgaagcgcaggcgttgctggccactctcggccagggccgcgaggaggatcggccggtg
tggttggggtcggtgaagtcgaacatcgggcacacgcaggccgcggccggtgtcgccggg
atcatcaagatggtccaggcgatgcggcacgggattctgccgcggactctgcacgtggac
gagcccaccacgcacgtggattgggctgccggtggggtgcgggtgttgaccgagcagatc
ccgtggccggagaccggccgcccgcgtcgggccggggtgtcgggcttcggcatcagtgga
accaacgcccacgtgatcctcgagcaggcacccggtgaagccgagcgggtgaccacagtg
gacaccggagcgccggtgccggtgttggtgagtggccgttccggctcggcggtgcgcgac
caggccgcgcggctggtgagcctgctggaccgtgaccgcggccttgctgtgacggatctc
gcgtggtcgctggcgaccacgcggtccagcttcgaccaccgtgccgtcgtggtggccgcg
gaccgggcggagctggccccgaagctccgggcgctggccgccggcgaggcggatccggcc
gtggtgaccggcgtcgccgcgagctccggcggtgtggtgttcgtgtttcccggtcagggt
tcgcagtggtctggcatgggccgcgagctgctggagacctcacccgtcttccgggaatgg
atcctgaagtgccaggaagcgttggcgccgtgggtgacctggtcactgaccgaagtcctc
accggcgaccacgccgagctggccgagcgggtggacgtggtccagccggtgttgtgggcg
atgatggtttcgctggccgagctgtggcgctcctacggcatccatccggaggcagtggtc
ggccacagccagggggagatcgcggccgcctgcgtcgccggcgcgctctcgctcgaggac
ggtgcccgggtggtggcgctgcgcgcgcaggcactgcgtgagatcgccggacagggtggc
atgctctcggtcgccttgtcgcaggacgaggtacggcactggctcgctcgtggcgatggc
cgcgtgtcgcttgccgcgatcaacgccgccgcgtccgtcgtgctcgccggcgaggcgacg
gtgctggaacggctgcggtccgagatgaccgagcagggaattcgggctcgtcgcgtcgag
gtggactacgcgtcgcactctccccacgtcgagcaggtccgcgatcgggtgctggcggcc
ttggcgccgatcacaccacgcacggctgacgtgaagttcttgtccacagtggactcggtt
tggctcgacggcaccgagctcgacgcggactactggtaccggaacctccggcagacggtc
cggttcgagccggccgtccgcacgctgctggccgacggataccaggccttcgtggaaacg
agcgcgcatccggtgatcacggtcccgctttccgagaccgtggaggacgccggcgcgcac
gcggtggtgacgggaacgctgcgccgcgaccaagggtcgttgcggcgcatgctgacctcg
ctggcgactctgcacacggccggggtgaaggtggactggacccgggtgttcggggccgag
ggccgacgggtcgagctgcccacgtacgcgttccagcatcagcgcttctggccggcgtcg
gcgccggtggaggcgctgagcggctggggttacgacgtcgtctggacgccggccccgcag
ccggcctcgccccggacgcccggttcgtggtggctgatcgcgccggccgggtacgaggaa
tcgccgttgatcaccgggttgcgccaggagctggccggcgccggcgcgacggcggatctg
gtggtggtgccggccgagcggaccgaccgggcggcgctcgccgcgaggatcggcgaactg
gccgtgccgaccggggtggtgtctttcctggcctggcacgacatcccggtcgcccagggc
tccgaggtctcgctggggctgaccctcacggccacgctcctgcaggccctgggtgacgcc
tcgatccaggccccggtgtggtccgtgacccgtggcgcggtcagtgtggccgacctcgcg
gaggtgtcccacccggcccagacggcggtctgggggtggggccggaccgcggcggtggag
tatccccggcgctggggcggcctgatcgacgtgcccgccggcgaacccgacgcgatcctg
accgcacgcttggcgcaggtcctgatgtccggcggcagcacggaagaccagctcgcgatc
cgtccatccgggacctgggcccgacggctcgcccgtcgcgccctcaccccggccgacgtg
ccggagtgggaggttccggtcgcgggcaccgttctcgtcaccggcggtaccggtgcgttg
ggcggtcacgtcgcccggtggctggccaccagcggcgtcccgcacctcgtgctcctcagc
cggcaaggcctccaggccgatggtgcgcgggacctggaagcggagctgacggggctcggg
gccagggtgacggtggtggcttgcgacgcggccgaccgggaagcgatggcggaggtgatc
gccggggttcccgcggagtatccgctggcgggggtcgtgcacaccgccgtggtcgtcgac
gacgggatcatcgaaaccgtgaccggtgagcagctggccacggtgttccggcccaaggtc
gacgccgccgtggtgctgcacgagctcacccgggacctggacctggcgatgttcgtgatg
ttctcctcgatcagcgccaccctcggcggtgtcgggctcagcacgtatgcggccgccaac
gcctacctcgacgggctcgcccagtaccgccgggcccagggacttcccgcgacctcgatc
gcgtgggggacgtgggcgggcgacggtctggcgtccgcgaccgcggcacagcagaacctg
cgccgcttcggcatgatcaccatggcgcccgctccggcgctggaaggcctgcgccgggtg
ctcgagcgcggcgacgccaccgccgtgatcgccgacgtggactggaagcagtacctcagc
gtgttcacggccgcgcggcccagcgccttgctcggcgacctcccggaaacccgtcagtcc
acaacggaccaggacgacagcggggcgaagctggccctcgacccggccgtgcggctgcgg
acccggctcgccgggctggctcacgccgaccaggttcgcgtggtgctcgacctggtgcgg
gtacagctggcggcgattctcgggtacggcgactccgatccgattccggagaatcgggcg
tttcgtgatctgggtttcgactcgctcacggcggtggagttgcgcaacatcctgagcatg
gccacggggctggatctgccccggactctggttttcgactatccgacccccaccgacctc
gcccggcacctgctcgacgagctctcgggcgacggcgcggacgagcccgcggcccttgcc
ccggcgcgggttccgtcggacgacgacccgatcgtcgtggtcggcatgggctgccggttc
cccggcggggtgagctcgccggaagacctgtggagtctggtcgcttccggcggcgacgcc
atctcggagttcccggccgaccggggctgggacctggcgggcctgcgtgccgggggttcg
acgacccggctgggcggtttcctcgacgaggtggccgagttcgacgccgggttcttcggg
atctcaccgcgtgaagcactcgcgatggacccgcagcaacgtctgctgctcgaaaccgcg
tgggaagcgctggagcgggcggggatcaagcccgcctcgctgcgcggcacccggaccggt
gttttcgtcggctcgagcatccaggactacatccacgcgtcgatgcaggtccgcgaagac
ctcgagggctacttgctcaccggcagctcgtccagcgtgctgtcgggccgcgtcgcgtac
ctgctcggcctcgaaggccccgcgatcaccgtcgacacggcgtgttcgtcgtcgctggtg
gcgctgcactgggccgcgcagtcgctgctgtcgggtgagtgcgagctggcgctggccggc
ggtgtcaccgtgatgtccacggcggagttgttcctcgacttcacccggcaaggcgcgctg
tcagtggacggccggtgcaaggcgttcgccgagacggccgacggtgccgggttctccgaa
ggggtcggtgtgctcgcggtcgagcggttgtcgtcggctcgggcggcgggtcgccgggtg
ctggcggtggtgcggggttcggcggtgaaccaggatggcgcgtcgaatgggttgacggcg
ccgaatggcccgtcgcagcagcgggtgatcaaggacgcgttggctcgggcgggggtgtcc
gcgggggagatcgacgctgtggaggcgcacggcacgggtacgcggctgggtgatcccatc
gaagcgcaggcgttgctggccactctcggccagggccgcgaggaggatcggccggtgtgg
ttggggtcggtgaagtcgaacatcgggcacacgcaggccgcggccggtgtcgccgggatc
atcaagatggtccaggcgatgcggcacgggattctgccgcggactctgcacgtggacgag
cccaccacgcacgtggattgggctgccggtggggtgcgggtgttgaccgagcagatcccg
tggccggagaccggacggccgcggcgcgcgggtgtgtccgggttcgggatcagcggcacc
aacgcccacgtcgtgctcgaacaagcacccgagcagccggaagtcgaacccgccggcatc
accgcgcccgtgccgctcgtgctctcggggcagtccgtgcccgcggtgcgggggcaggcc
gcccggctggccgagctcctcgacggcgatggcgatgcggccctggccgatgtggcctgg
tcggcggcgctgacccggtcggccttcgaccaccgtgccgtggtggtggccgccgatcgg
caggaggcgttgtcgagcttgcgggcgcttgccgcaggggagcctggtccgactgccgtg
accggggaggcgcgggtgtccgggggcgtggtgttcgtgttccccggtcagggttcgcag
tgggccgggatgggccgggagctgctggagacgtcggcggttttccgggagtccattcag
gagtgtcaggacgcgttggcgccgtggatttcctggtcgttgaccgacgtcctcgaccgt
gcggacctgctggaacgggtcgacgtggtccagccggcgttgtgggcgatgaacgtttcg
ctggcgaagctgtggcggtcccacggggtcgaaccggccgccgtgatcggacacagccaa
ggcgaaatcgcggccgcctgcgtcgccggagccctctcgctggaagacggcgcccgtgtg
gtcgccctgcgcgcgcaggcactgcgagtgttggccgggcacggcggaatgctctcggtc
gcgctgtcgcaggacgacgttcgggaatggctggtccgctacgacggtcagctctcgctc
gccgcggtcaacgccccgacctccgtggtcgtcgcaggcgacacggcggccttggcgcac
ctgcagaacgaactgactggccacgacatccgggcgcggcggatcgaagtggactacgcc
tcgcattccccggaagtcgagcaggtccgggaccaggtgctcgagaagctggcgccgatc
acgccccgcacgcccggcgtgaagttcttctccacagtggacgagaagtggctggacggc
acggaactcgacgcgggctactggtaccgcaacctccgccggaccgtgggcttcgaaccc
gccgtacgggccttgctggccgacgggtaccgggcgttcatcgaggtgagcccgcacccg
gtgaccacggttccactcaccgaaaccgcggaggcggccgggacaccggccgtcgtgacc
ggcacgttgcgccgtgaccaggggtcgcggcaccgggccctgacctcactcgccagcctc
tacgcggagggaatcgacctcgactgggccgcggtcttcgccggaatcggcgccggcggg
aggcgggtcgatctgcccacctacgcgttccagcgccggcgctactggccggagatcacg
gcacaccccgtccagggaccgcgggtggaagacctggtgctgaacctggactggaccacc
gagcccgacccgacgggtgccggtgcagcaccgcgaacctggtggctgctcgacgaccac
cacaacggggtctcgaccctgcccggcgagctgggcgtgtcacgggtggtggacgacctc
gtcgagctgggcaagcagctcgacaccggtgaccgggccccggacgcgctgctggtgccg
gtccacggtccggacggcgacgtgaccgccgcggtgcaggccaccaccgtcgaggtactg
ggtctgctgcagcagtggctggcgaaaaccgagttttccgggattcgattggtgttcctc
acgcgtgacgcggtgagcgccgagtccacgaccgatctcgctgcggccgcgatctggggc
ctggtgaagtcggcgcaggccgagcacccgggccggttcacgctcgtcgaccacgatcgt
catccgctttccgccggcttgctggccgaagccctggccaccggggaaccgcagctggcg
atccgcgcccaccgggtcgcggtcccgcgactggcacctgcgcgtgagcaggagccggcg
gcgccggtccgctgggaccagggcaccgtggtcatcaccggcgggaccggcgggctgggt
gccgcgctggcgcggcacctggtcgcaggtggccgggcgaaccggttgttgctgctcaac
cggcggggacacgacgccccgggcgcggcggagctgcgggccgaactgaccggtctgggt
gccgaggtcacgatcacggcctgcgacatcgccgaccgcgctcggctggccgaagcgctc
gacgcggtgcgcccggtgtcggcggtcgtccacacggctgtggtggtcgcggacggcacg
atcgagtcgctgacgccggaagcggtcggccgcgtgttcgagcccaaggtgcggggcgcg
tggaacctgcacgagctgacgcagggcgacgaactgtcggcgttcgtactgttctccgcg
atggccggcgtcatgggcacgcccgggcagggcaactacgccgccgccaacacgttcctg
gacgccctggcccggcatcggcgggccggtggcctgccggccgtgtcgatggactggggc
acctggacttccgacgtgggcttggccagcgcactgtccgatacggaccttcggcgcctc
gcccgcacgggattcccggccatgagcatcgacaacggcctggccctgttcgaccgggcc
atgaccgtcgacgagccgatcgtggcacccgtccggctcgaccgcgtcgcggcggccgcc
cagccgtcgcggctgctggaggatctcgtggtgcgccggcccgagccggccggcacgccg
accgagcccgagaccgggccgcgactggccgaccggctcgcgaccctgaccccgaccgac
cggatccggacgatgacggacctggtccgtggtcaggtcgccgccgtgctcggacacacg
acgccggatgacgtccggcccacccaggcgttcaaggacatcggcatggactcgctcacc
tccatcgagctgcgcaaccggctcaacgaagccaccgggctacggttgcccaccaccatc
gcgttcgacaatccgaacccggaggtcctggccggtcacctcgtcgcggagctgatcggg
accaccacggtggccgtcgcggtcacgggatcggtgaccacccagctggacgcgcttgag
accaccttcctgaccgtcgcgctcgacgcgacggcgcggccgatgctgcggaagcggctg
agggcgctcctgggccggatcgacgaggcccccacgacctcggagtcgccgcagtcctca
gtggacacggcatccgacgaagaccttttcgccatgctcgacgaccagctggggcactga
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