Aristolochia californica: 137941235 Help Entry 137941235         CDS       T10486                                  Name (RefSeq) auxin transport protein BIG   KO K10691   E3 ubiquitin-protein ligase UBR4 [EC:2.3.2.27] Organism acak  Aristolochia californica Brite KEGG Orthology (KO) [BR:acak00001]  09180 Brite Hierarchies   09182 Protein families: genetic information processing    04121 Ubiquitin system [BR:acak04121]     137941235 Enzymes [BR:acak01000]  2. Transferases   2.3  Acyltransferases    2.3.2  Aminoacyltransferases     2.3.2.27  RING-type E3 ubiquitin transferase      137941235 Ubiquitin system [BR:acak04121]  Ubiquitin ligases (E3)   Single Ring-finger type E3    UBR box proteins     137941235 SSDB OrthologParalogGFIT Motif Pfam:  E3_UbLigase_R4 UBR4_TPR UBR4_Ub UBR4 zf-UBR_1 ZZ TFIID_20kDa Motif Other DBs NCBI-GeneID:  137941235 NCBI-ProteinID:  XP_068642658 LinkDB All DBs Position Unknown AA seq 5105 aa AA seqDB search MADQISKILELFLTEKAPKDLAQKLHSDTAKAFLESFYSILEQALEPIGDGKLGFQNWNN SQVQSVASVGRLIVSASRSLSVELVESIFIGLVEKSLEFATCYLEKSLTDGVDMSSQSGI LQLLETALIDELLVEFDVPHLCTLNSLAESLPVLSRKGESVNLDKHIKCNIQGINCSKDT RPVDRVLITLASESLQTDSQDTQFTELAFRQESSSMLSLGRHLAVVHVRCVHRLIIICRD MVQTPEVFEERKEDANFRSRLTFSLKILKLLGNLTKNSPYVAYDAELLNAVSSFADIFPN LFKTRFDFLNHDAASSHETGLDSLLLFLLEEFLQFVHVVFCDGAIFHNIQTCIIASLLDI LDVNVWRYDKSEDVLKAPLVYSPRVVMYLLKLVGNVKNWTSQIHIWEEKLDVDPSGSYSF GDGTSAPSCYVRSVKVSLLKKYTCEEHLKLMLPQSSQWVDSMMHLAHFLHSEGVKSKQKV DRLRSGSVKTGGASDTESAVSHEDEALFGDLFSEAGRSVVPSDGPEQGSVSACSISACCN VLIQAATELLSFLKVYIFSPEWHSTVYEDARSKLKDNHVDFLISILLCQVCYADERVLES YTTLPANRRVAPINEVCFELLHSLIVHRALSDSLEEHFVDEILKVDCAAFAYNDHTLTLL AHILICKVGPAGSQLRARIVDSYVQFILDKAKIVCSKCPNLMREFVPTLPCVLHLEILLM AFHLSSENEKASLAAFVFSSLKAMDVPSDGCSVLQLSCWSLLVSRLVLVLRHMISYSTSY PSWLLLRLRSKLRETPARSSHSHAITESLPSWVSIMVRTIMGEAVKELAGITSLLPQLID VVIVPGSVYRDDQAFLHLGLSWIELCDTFASILGLWKGKKAETVEDLILERYIFSICWGT LGIGSASCEPLPLRLNLQDLDISNVKSLYHFGHAFVNDKHNLSEVVMRVLNQLHSVHIPC KTDEQGWDLVRYGAWLSLVLSLLHAGVWEFAVNNAVPGVEQFWTEQTPKDVEFLTLGSTV VATLFQSNQLGWLLKVLSSLLTKHLKALQVAFAATLDRNRCYVGRFSPLLLLKHTIFQKC TKSELLDKCGSCTSVLESIYGLLPKLDEVINKEDSGSTARVFLSSWLHGFPSHSPTSSVA LISCILSVRGIVCTLDGLLKVKDAGGGNILVDGEVLHELLESVITVKSDMIFQHIHGNCA AIYNNLTSFKKERQDYSYLFVLKHMEDFLTEVSCSEVIDNDTHDTIILSAVDFIEDLRKD PSKSGIFDFYVGAGEVCEEEKELYGGKRGNLLVLFEVLSGCYSEPVNVKVLNFLVDLLTG EVCPGLKDSIQKKFLGMELPCLSDWLERRLLGGVKDASGALTSTKGNSVSLRESTINFIL CLVSIPETQSKAVQSRFIEALLTLLDGAFIIYDIHVAKAYFNFLVQLSNGEPSMKQLLKM IFTLIEKLAGDENKLQGLKFLFGFLGTVLNACGASKNVVDKLSGKYLSSNSFGAESAVSR SVGSRKNSETLIIPSNQEPGSASLDCDATSVDEDEDDGTSDGELASVDRDDEEDSSSEKA LASKVCTFTSSGSNFMEQHWYFCYTCDLTVSKGCCSICAKVCHRGHRVVYSRSSRFFCDC GAGGVRGSSCQCLKPRKFTGSSTNVPSRGPNNFPSLLPLAEDGDQTPDSDSEPEDDAYMD VENPFKLSIPKEVQEALPLLLQEVDVEGRVLELCNKLLPLVISRRDTSLLKDMKVVLGEQ KVLSLNIDLLQLKKSYKSGSLDLKIKADYSNSRELKSHLNSGSLIKSLLSISKRGRLAAG EGDKVTIFDAGQLIGQPTVAPVTADKTNVKPLSKNVVRFEVVHVMFNPIVESYLAVAGFE ECQVLTVNPRGEVTDRLPIELALQGAYIRRVDWVPGSQVQLMVVTNLFVKIYDLSQDNIS PIHYFTVENDFIVDATLVVAPKGRLFLLVLSGLGCLYRLELTMGGEIGARSLREIIQVQG KEKLGKGLSLYFSLAYKALFLSYQDGTTLIGRLNANATCLTEISAVYEDEREGKLRNAGL HHWKELIAGSGVFLCFSSLKSNAAFVVSLGPHELLAYNIRSGGSTLPLVGITSYRPLSKD KTQCLVLHDDGSLQIFSHVPLGADNAANVPSDQSKKLGSGILTNRVYASSIPEFPLEFFE KTVCITADVKFSGDAVRNSDSDGAKQSLASDDGFLESPSPRGFKMTVSNSNPDIVMVGIR VQVGNTSLSHIPSDITIFQRVIKLDEGMRSWYDIPFTVAESLLADEEFIISVGPTFNGSA LPRIDSLEVYGRAKDEFGWKEKMDAVLDMEAHAFGSSSGTAGTGKKGRLLQTAPVQEQVV ADGLKLLSRYYSLCRSQACPDTDKVKAELSTLKCRKLLETIFESDREPLLQSAACHVLLA VFPRREMYDQVKDTMRLLGVVSSSPLLISRLGVGGATAGWVIQEFTAQVRAVSKIAVHRR TNMASFLESHGTRVVDGLMQVLWGILDLEQPDTQTINNIVIPSVELIYSYAECLALHGND GVGRSVKPAVVLLRKLLFAPYEAVQTSSSLAISSRLLQVPFPKQTMLASDDSVETTSSAP VNSGIHGATGGNTQVMIEEDSTTSSVQYCCDGCSTVPILRRRWHCNVCPDFDLCETCYEV MDADRLPPPHSRDHPMSAIPIEVDSIGGDGNEIHFSMDELNEPSILQVASDINIQKSSPP VHLLEHNETSGEFAPVVDQRIVSISAPKRMVNSLILRELVTELRGWMETTSGHRAIPVMQ LFYRLSSAVGGPFMDASKPENLDLEKFIKWFMDEINLSKPSVAKTRSSFGEVVILVFMFF TLMLRNWHQPGSESSLQKLADNPEKGVVQIPSSSSAASPSIGDQEKEEFVSQLLRACSLL RQQVFVNYLMDILQQLVHVFKSPPTNLEATHGLTAGTGCGALLTIRKELPAGNFSPFFSD SYAKSHRSDFFVDYHRLLLENTFRLVYSLVRPEKQDKSAEKDRHDKSVYKSSPGKDLKLD GHQDVLCSYINNPHTTFVRRYARRLFLHLCGSKTHYYNVRDSWQLSNEVKKLYKLIDKTS GLQNPVSYERSVKLVKCLLAISEVAGARPRNWQKYSLRHGDVLSFLMNGLFTFGEESVLQ TLKLLNLAFYTGKEMVQSTQKTEAGDGGSSSNKAGAHFDAKKKKKGDDGNENGSEKAYMD MEPAVYIFSDKDGSTLRRFIDLFLLEWNSAAVRLEAKCVLYGVWHHGKQQFKENMLKVLL EKVKYLPVYGQNIVEYTELLIWLLGKVPEGTLKQQDTELVTRCLTTEVIKSIFDTLHSQN ELLANHPNSRIYNTLNGLVEFDGYYLESEPCVACSCPEVPYTKMKLESLKSETKFTDNRI IVKCTGSYTIQTVTMNVHDARKSKSVKVLNLYYNNRPVSDLSELKNNWSLWKRAKSCHLA FNQTELKVEFPIPITACNFMIELDSFYENLQASSLESLQCPRCSRSVTDKHGICSNCHEN AYQCRQCRNINYENLDSFLCNECGYSKYGRFEFNFMAKPSFIFDNMENDEDMKKGLAAIE SESENAHRRYQQLLGFKKPLLKLVSSIGENDIDSQHKDSVQQMMVSMSGPSCKINRKIAL LGVLYGEKCKAAFDSVSKSVQTLQGLRRVLMSYLHQKHADSRLSTSVFMVPRSPTNCYGC ATTFVTQCLELLQVLSKHSNCKKQLVSAGILSELFENNIHQGPKAARVQARAVLCAFSEG DANAVAELNNLIQKKVMYCLEHHRSIDIAVSTCEELLLLSETCSMADEFWEARLRVAFQL LFSSIKLGAKHPAISEHVILPCLRIVSQACTLPKPEAVDKEQGMGKLPTALQAKDDSSTN ASASPSGLTNGNKSSSELSDKHWDNNRKGQDIQLVSYSEWEKGASYIDFVRRQYKISQGV KTTIQRSRRDPQRLDYLALKYALRWKRRASRGMSNSNFSGLELGSWVSELVLSACSQSIK SETCSLLSLLCGQSSSRRFQLLSLLIGLLPSTLSAGESAAEYFDLLFRMIELEDARLFLT AKGCLTTICKLISKEVSNIASQEKSLHVDISQGFILHKLIELLSKYLDVPRIRFRFMRDE LLSEVLEALLVIRGLIVQKTKLIGDCNRLLKDLLDGLLLESSENKRHFIRACISGLQNHG EERKGRTSLFILEQLCNIICPSKPEPVYLLILNKAHTQEEFIRGSMTKNPYSSAEIGPLM RDVKNKICHQLDLLGLLEDDYGMELLVAGNIISLDLSISQVYEQVWRKSHNQTASNLVGS GGFNSTSTRDTPPMTVTYRLQGLDGEATEPMIKELEEEREESQDPEIEFAIAGAVQECGG LEIILGMIQHLRDDELKSNQEELGSVLNLLMYCCKIRENRRALLRLGALGLLLETARRAF SVDAMEPAEGILLIVESLTMEANESDIGITQSVLVTDDETGAGEQAKKIVLMFLERLCHP FGLKKLNKQQRNNEMVARILPYLTYGQTAAMEALILHFDPYLQDWSEFDRVQKQHLENPK DESLAEQAAKQRFALENFVRVSESLKTSSCGERLKDIILEKGITAVAVRHLSESFACAGQ AGFKTSVEWAFGLKLPSVPLILSMLRGLSMGHSATQRCIDDGGILPLLHTLEGVSVENEI GARAENLLDTLSDKEGKGDGFLGEKVHMLRHATKDEKRRQALRKREELLQGLGMRQEVAS DGGERIVVSRPIIEGLEDVEEEEDGLACMVCREGYSLRPNDMLGVYSYSKRVNLGVGTSG SSRGECVYTTVSHFNIIHFQCHQEAKRADAALKIPKKEWEGATLRNNETLCNCIFPLKGP SVPLAQYVRCVDQYWDNLNALGRADGSRLRLLTYDVVLMLARFATGASFSTDCNGGGRES NSRFLPFMIQMARHLLDQGGSNQRKAMAKSITSYLSSVSPSDPKPSASSGTRGTNGTEET VQYMMVNSLLSESYEEWLQHRRGFLQRGIYHAYMQHSHGRMTPLRLSDPTAVVRSEGSLS DSSDETNLFQIILPMLVYTGLIEQLQKFFKVNKAGNLAQGRTGGTNTESEGDERWEVAMK ERLVNVKEMVGFSKELLSWLEDMASASDLQEAFDVMGALGEVLSGGFTHCEEFVQSAIGM GNANR NT seq 15318 nt NT seq  +upstreamnt  +downstreamnt atggctgaccaaatatccaaaattcttgagcttttcctgacagaaaaggctcctaaggat ctagcgcagaaacttcactctgataccgccaaggcatttctcgaaagcttctattcgatc ctcgaacaagctcttgagccgatcggagatggaaagttaggtttccagaattggaacaac tcgcaggtgcagtctgttgcgtctgttgggagactgattgtctctgcatctcgttcttta tctgttgagctcgtggaatctatatttatcggtctagtggagaaaagtttggaatttgct acttgttatttggagaaatccttgactgatggagttgacatgagttcgcagagtggcatt ttgcaacttctggagactgcactcattgatgaactacttgtggaatttgatgttcctcat ttgtgtactttaaatagccttgcagaatctttaccagttctatcgcgtaaaggagaaagt gtgaatttggataagcacatcaaatgcaatatccaagggatcaattgctcaaaggacaca aggcctgtggatagagttttgatcactttggcatctgaaagtttgcagacagactcccaa gatacgcagttcacagaacttgcatttcgccaggagtcgagtagcatgttatctcttggg cggcatttagcggttgttcatgtgagatgtgtacatcggctcattattatctgtagagat atggttcagacgcctgaggtgtttgaagaacggaaggaggatgcaaactttcgttctaga ttaactttcagtctaaaaattctgaagctactcgggaatctcacgaagaatagtccatat gttgcttatgatgctgaattattaaatgcagtttcttcctttgctgatatatttcctaat ttgttcaaaactaggtttgattttttaaaccacgatgctgcttcatcacatgagactggc ttggacagcctcttgttgtttctgttggaagaatttcttcagtttgttcatgttgttttc tgtgatggtgcaattttccataatattcagacatgcattattgcttctctattagacatt ttggatgtgaatgtgtggaggtatgacaaatctgaagatgtcttgaaggcccctttggtt tactccccccgtgttgttatgtatcttttaaagcttgttgggaatgttaagaattggaca tcacagattcatatttgggaagagaagttggatgtagatccttctggtagttacagtttt ggggatggaactagtgctccctcatgctatgttcgttcagtgaaggtttccttgctaaaa aagtacacctgtgaggagcacctaaaactgatgctgccacaatcaagtcagtgggtggat agtatgatgcatcttgctcatttcctacactcagaaggagtaaaatcaaaacagaaggtt gatcgattacgctcaggctctgtgaagactggtggtgcatctgacacagaaagtgcagtt agccatgaagatgaggcccttttcggagaccttttttctgaagctggtcgctctgtggta ccatctgatgggcctgaacaaggttctgtttcagcgtgtagcatctcggcctgttgtaat gtgcttatccaagcagcgaccgagctattaagttttctgaaggtgtatatcttttctcct gaatggcattctactgtttatgaggatgcccgtagtaaactgaaggataaccatgttgat ttcttaatctcaatactgctctgtcaagtttgttatgctgatgaaagagttctggaaagt tatacaacattgcctgcaaataggagggttgcacccattaacgaggtgtgctttgaattg ctgcacagtcttattgtgcaccgtgctttgtctgattctcttgaggaacattttgttgat gaaatattgaaggtagattgtgcagccttcgcttataatgatcatactctcactctttta gcacacatccttatttgtaaggtgggtccagctggtagccagctaagagccagaattgtt gatagttatgttcaattcatcctagacaaagcaaaaattgtctgttcaaagtgcccaaat ctcatgagggaatttgtacctacacttccttgtgtcctacacttagaaattcttcttatg gcatttcatttatcctctgagaatgaaaaagctagtctggcagctttcgtgttttcatca cttaaagcaatggatgttccaagcgatggatgtagcgtgttgcagctttcatgctggtct cttttggtgtcaaggttggttttggttcttcggcatatgatatcatattcaactagctac ccttcttggctgttgttgcgtttgaggtccaaactaagggaaactccagctaggtcatcc cattcacatgccataacagagtctttgccatcatgggtatctattatggttaggactatt atgggtgaagcagtcaaggaacttgctggtattactagcttgcttcctcagctgatcgat gttgttatagtacctggttcagtctatagggatgaccaagccttcctccacttaggttta agctggattgagttgtgcgacacgtttgcgtcaatcctcgggctctggaagggtaagaaa gctgaaacagttgaagatctcatacttgaaagatacatctttagcatctgttggggtaca cttggaattggctctgcatcttgtgagcctcttcctttgaggctgaacttgcaggacctt gatatctcgaatgtgaaatctttatatcattttggtcatgcttttgtgaatgacaagcat aatctgtcagaagttgttatgagagtacttaatcagttgcattctgtgcacataccatgt aagactgatgaacaaggatgggacctggtaagatacggggcttggctgtcgctggtgctt tctctgcttcatgcaggagtatgggaatttgctgtaaacaatgcagtccctggagtggaa cagttctggactgaacagacacctaaggatgttgaatttcttactcttggcagcactgtg gttgcaaccttgtttcagagcaaccaacttggttggctactgaaggtactgtcatctttg ttgacgaaacacctgaaggctctacaagtagcatttgctgcaactctggatcgaaacaga tgctatgtgggtagattttccccattgctgctacttaaacatacaatttttcaaaagtgc acaaaaagtgagctacttgacaagtgtggatcatgtacttctgtgctggaatctatctat ggtctcctgccaaaattggatgaagttatcaacaaagaagattctggaagcacagctagg gtctttcttagttcatggcttcatggctttccatctcattctccaacctccagtgtagct cttatttcttgtattctcagtgtgagaggcatcgtatgtactctagatggccttctgaaa gtgaaagatgctggaggtgggaatattctggtagacggagaagtattgcatgaacttctt gagtcagtaatcactgttaaatctgatatgatttttcaacatatacacggcaactgtgca gctatttataataatctgacatcattcaagaaggaaaggcaagattacagttatctgttt gtgctgaagcacatggaagatttccttacagaggtcagctgcagcgaagttatagacaat gatacccatgacacgataattttgagtgctgtagatttcatagaggatctgagaaaagat ccttcaaagtctgggattttcgatttttatgtgggtgcaggagaagtttgtgaagaagag aaagaactatatggtgggaagcgtggaaacctgttagtcctatttgaggtactcagtgga tgttactctgaaccagttaatgtgaaagttctgaattttcttgttgatcttttgactgga gaggtttgtcctggacttaaagatagcatacaaaagaaattccttggtatggaattacca tgtctctctgactggctggagaggaggctgctaggaggtgtcaaagatgcttcaggggct cttacatctacaaaaggaaacagtgtttcgcttagagaatcaactataaatttcatcttg tgccttgtgtcgattcctgaaacccaatcaaaggctgtccaaagtcgttttatagaagct ctactcacattgctagatggggcattcattatttatgatattcatgtagctaaagcttat ttcaactttttagtccaactttcaaatggggaaccatcaatgaaacagctattgaaaatg atttttactttgattgaaaagcttgctggtgatgagaataaacttcaagggttgaaattc ctttttggctttcttgggactgttttgaatgcttgcggggccagtaagaatgtcgtagat aagctttcaggtaaatatttgtcaagcaatagctttggggcggagtctgctgtttcacga tcagttggttcaaggaaaaattcagagacactgattattccttcgaatcaagaacctggt tctgcatctcttgattgtgatgcaacttccgtggatgaagatgaagatgatggtacatca gatggggaattggcttctgtagacagggatgatgaagaggatagcagtagtgaaaaggcc cttgcatctaaagtttgtacttttacttccagtgggagcaatttcatggaacagcattgg tatttttgttacacctgtgatctcactgtttcaaaaggctgttgctcaatttgtgccaaa gtctgtcaccgtggtcatcgtgttgtctattctcgttcaagtcgctttttttgtgattgt ggagctggaggtgttagggggagcagttgtcaatgcctgaagccacggaagttcactgga agcagcaccaatgttccttctcgtgggcccaacaattttccttcacttttgcctttagca gaggacggagatcaaactcctgacagcgattctgaaccagaggatgatgcttatatggat gtagagaaccctttcaaattgtctattccgaaagaggtgcaagaggctcttccattatta cttcaagaagttgatgtagagggtcgagtgcttgaactttgtaacaaactattgccctta gttattagcagacgagatacaagtctgttaaaagatatgaaagtggtccttggtgaacag aaagtactttcattgaacattgatctcctgcagctgaagaagtcctacaagagtggctcc ttagacctgaagataaaggcagattactcaaatagcagggagctaaaatcccatctaaac agtggttctcttataaaatccttactgagcatcagtaaacggggtaggcttgctgctgga gagggtgacaaagttacaatatttgatgctggccaattaattgggcagcccactgttgct cctgttacagcagataagaccaatgtgaagcctctttccaagaatgttgttcgttttgag gtagttcatgtcatgttcaacccaattgtagagagttatcttgctgttgctggctttgaa gaatgccaggtccttaccgttaatccacgtggggaggtaactgatcgccttcccattgaa cttgctctgcaaggtgcctatattcgaagggtggattgggtgccaggttctcaggttcaa ttaatggtggtgactaacttgtttgtcaagatctatgatttatctcaggataatattagc cctattcactacttcacagtggagaatgatttcattgtggatgctacacttgtagtagct cccaaaggaaggctgtttctccttgttctgtcagggcttgggtgcttgtacagactagaa ttgactatgggaggtgaaattggggctaggtcattgagagaaatcatccaggtccagggg aaagaaaagcttggaaaaggtctctctttgtacttctcgttggcatataaagcacttttc ttgtcatatcaagatggaactaccttgattggacgcttaaatgcaaatgccacatgtctg acggagatatcagctgtttatgaggatgagcgtgagggtaagttgaggaatgctggattg caccactggaaggaattgattgctggtagtggggtctttctttgcttctcaagtctcaag tcaaatgcagcatttgttgtttcgttaggtccacatgaattattggcatataacattcgc tcaggggggtctacattacctttggttggaatcacttcttacagacctttatctaaagac aaaacacagtgccttgttttgcatgatgatggcagtcttcagatattctcacatgttcct ctgggagctgataatgcagctaatgtaccttcagatcagtcaaagaaactaggatctggt attcttacaaatagagtttatgcttcttcaattcctgagtttcctttggaatttttcgag aaaacagtttgtattacagctgatgtaaagttcagtggtgatgccgtcagaaacagtgat tctgatggagcaaaacaaagcttggcatcggatgatgggttcctagagagtccaagtccc agaggttttaagatgacagtatcaaactctaatcccgatattgtaatggttggtattcgt gtgcaagtgggtaacacttcattgagccatatcccttctgacatcaccatctttcagaga gtaataaaactggatgaaggcatgaggtcatggtatgacattcccttcactgttgctgaa tcacttcttgcagatgaggagttcatcatctctgtgggcccaaccttcaatggatctgct ttgccaagaatagattctttggaagtttatggtcgtgctaaggatgaatttggctggaaa gagaaaatggatgcagtgcttgacatggaagcccatgcttttggttctagttctggaaca gcgggaactggaaagaaagggcgattgctgcaaacagctccggtgcaggagcaagttgtc gccgatggcctcaagcttctatctagatactactctctgtgcagatctcaggcatgtcca gatactgacaaagtcaaggcagagctaagtacattgaaatgcaggaagctactggaaaca atatttgaaagcgacagggaaccattgttacaatctgctgcttgccatgttcttctggct gttttcccgagaagggaaatgtacgatcaggtgaaggacaccatgcgacttcttggggtg gtaagttcttctccattgcttatttcgcggttgggagttggtggtgctacagcaggttgg gttattcaagagtttacagcacaagttcgtgcagtgtcaaaaattgcagtgcaccggcga acaaatatggcttccttcctggaaagtcatggtactcgagtagttgatggtctgatgcaa gtcctgtgggggatcttggacttagaacaacctgacacccaaacaataaacaacattgtg ataccctctgtggagctcatctatagttatgctgaatgtcttgctttgcatggaaatgat ggagttggtcggtccgtcaaacccgcagttgtgttgctcagaaagctactttttgctcca tatgaagctgtgcaaacttctagcagcttggccatatcttcgaggttgctccaggttccg tttccaaaacagacaatgttagcttctgatgattctgtggagaccacatcatcagcacca gtgaattctggtatccatggtgcaacaggtggaaatacccaagtcatgattgaagaagac tctactacgtcttcggttcagtactgttgtgatggctgctctacagttcccattcttaga cgccgatggcattgtaatgtttgtccagattttgatctatgtgagacctgttatgaagta atggatgcagatcgccttcctccacctcattccagagaccacccaatgtctgctatacct atagaagttgattcaataggtggagatggcaatgaaattcacttctccatggatgaattg aatgaaccaagcatactgcaagttgcttcagatatcaatatacagaaatcttctccacca gttcatctcttggagcacaatgaaacttctggggagttcgctcctgtggttgatcagaga attgtgtcaatttctgcacccaagcggatggtgaactctcttatactacgtgagctagtt acagagctgagaggatggatggagacaacttcagggcaccgggctattcctgttatgcag cttttttacagactctcttctgcagtaggaggacctttcatggatgcctctaaacctgaa aatctggatcttgaaaaatttatcaagtggtttatggatgaaatcaacctaagtaaacct tctgtagccaaaacacgctcctcttttggagaagttgttattcttgttttcatgtttttt accttgatgcttcgaaactggcatcaaccgggtagtgaaagttctctacaaaagttggca gataaccctgagaaaggggttgtccaaattccatcctcatcttcagcagcttcaccttca attggtgatcaggagaaagaggaatttgtttctcagttgcttcgagcctgtagtttgttg aggcaacaagtctttgtgaactaccttatggacatcctgcagcagctggtccatgttttc aaatctccaccaacaaatcttgaagcgactcatggtttgaccgctggcactggatgtggt gccctacttaccattcgtaaagaattgccagccggaaacttttcaccattcttttctgat tcttatgccaaaagccatcggtcggatttttttgtggactatcaccgtctgctgcttgag aacactttccgcctggtgtacagcttggtccgaccagaaaagcaagacaagtctgcggaa aaagatagacacgataagtctgtttacaagagttctcctgggaaggatttgaagcttgat gggcatcaagatgttctctgcagctacatcaataatcctcatacaacatttgttcgcaga tatgcaagaaggttatttctacatttgtgtggcagtaaaacacattattacaatgttagg gactcttggcagttatcaaatgaagttaagaaactttataaacttattgataagaccagt ggtttacaaaatcctgtctcttatgagagaagtgttaaactggttaagtgcttgttagca atatctgaagtagctggagccagacctcgaaactggcagaaatatagcttgaggcatggg gatgtgctatcctttttgatgaatggtttattcacttttggagaggagtccgtacttcag actcttaagcttttgaatttggcattttatacgggaaaagagatggttcagtccacacag aaaactgaggctggggatggaggatcaagttctaataaagcaggggcgcactttgatgca aagaagaagaaaaaaggtgatgatggtaatgaaaatggttcagaaaaggcttacatggat atggagccagctgtgtatatcttcagcgacaaagatggatctactttaagacgtttcatc gatttgttcttgttggagtggaactctgcagccgtgagacttgaagcaaaatgtgttctt tacggtgtttggcaccacggaaaacaacaattcaaggagaatatgttgaaggtacttttg gagaaggtgaaatatttaccagtgtatggccagaatattgttgagtatactgaactcctg atctggctactggggaaggtccctgaaggtactttgaagcaacaggatactgaacttgta actcgatgtctaactacagaagtgataaagagtatcttcgacactctccactctcaaaat gagctattagccaatcacccaaattcgcgaatctacaacactctgaatggcctggtagag tttgatggttactaccttgaaagtgagccttgtgtagcttgtagctgtcctgaggtgcct tatacaaagatgaagcttgaaagtttaaaatctgaaacaaaattcactgacaatcggata atagtgaagtgtactgggagttatactattcaaaccgtgaccatgaatgttcatgatgct cgaaagtcgaagtctgtcaaagtactgaacttgtactacaacaataggcctgtctctgac ttgtctgaattgaagaacaattggtcactttggaagcgtgccaaaagttgccaccttgct tttaaccaaacagaacttaaagtggagtttcctataccaatcacagcttgcaatttcatg attgagctggattcattctatgagaatctacaagcttcttcccttgagtcattgcagtgc ccacgttgcagccgatcagttactgataagcatggaatatgtagcaattgccatgagaat gcctatcaatgtaggcaatgccgtaacataaattatgagaatctggattcttttctttgt aatgagtgtgggtatagcaaatatggacggtttgaattcaatttcatggcaaagccaagt ttcatatttgataatatggagaatgatgaagacatgaagaagggattggcagctatagaa tcagaatcagaaaatgctcatcggaggtaccagcaactcctcggattcaagaagcctctg ctaaagttagtttcaagcattggtgagaatgacattgactctcaacataaggattcagtc cagcaaatgatggtctctatgtctggcccttcttgtaaaataaaccgtaaaattgctctg cttggtgttctatatggtgagaagtgcaaggcagcttttgattctgtcagcaaaagtgta caaacactccaagggcttcgccgggttttaatgagttacctgcaccagaaacatgctgat agtagattgtcaacttcagttttcatggtccctaggtcaccgactaactgctatggttgt gctacaacatttgttactcagtgtcttgagctgttacaagttctttcaaaacattcaaac tgtaagaaacagcttgtgagtgctggaattttgtccgaattatttgagaataacatccat cagggccctaaagcagctagagttcaggcaagggctgttctctgtgccttctccgaggga gatgccaatgcagtggctgagttgaacaatctaatacaaaagaaagttatgtattgcctt gaacaccatcgttcaatagacatagcagtgtctacatgtgaggagttgttgttactatca gagacctgctctatggcagatgagttctgggaagcaaggttacgagttgcttttcagtta ttattttcttccattaagttaggtgccaaacatcctgctatttcagagcatgttattcta ccatgtttgagaattgtttcacaggcctgtactcttccaaagcctgaggctgtggacaag gagcaagggatgggaaagttacctacagctctgcaggcaaaagacgatagtagtactaat gcatctgcatctccaagtggcctaactaatgggaacaagtcctcatcagagttgtctgat aagcactgggataacaatcgcaagggccaggatatacaattggtgagctactcggagtgg gagaaaggagcttcatatattgactttgttcggagacagtataaaatctcacagggggtt aaaactactattcagaggtctcggcgagatccccagagattagattatcttgcacttaaa tatgcactgagatggaagcgccgtgcaagcagagggatgagtaatagtaacttctctgga ttagagttgggttcctgggtctcagagctcgttttgagtgcttgttcgcagtccataaag tcggagacttgctcactgcttagcttgctttgtgggcagagttcgtccagaaggttccag ttgctcagtttgcttattgggctccttccgtcaactttatcagcaggtgaaagtgctgca gaatattttgatttgctcttcaggatgatcgagttggaagatgctcggttattcttgaca gcaaagggttgcctaacaacaatatgtaagttgataagcaaagaagtcagtaatatagca tctcaagagaagagccttcatgttgacatatctcagggatttatccttcataagcttatt gagctcctcagcaaatatctggatgtgcccaggatccgattcagattcatgcgagatgag ttgctctctgaagttttggaggctcttcttgtcattcgagggctgatagtgcaaaagaca aaattgattggtgattgcaataggcttctgaaagacctcctagatggtcttctgcttgag agcagtgaaaataaacggcatttcatccgtgcatgtatctctggccttcaaaatcatgga gaagaaaggaaaggaagaacttctctgtttatcttagagcaactctgtaacattatttgc ccttcgaagcctgaacctgtttatttattaattctgaacaaagcacacacccaagaagag ttcattaggggctctatgaccaagaatccttattctagtgctgagattggtcccctgatg cgtgatgttaaaaataagatctgtcatcaactggatctgctaggtcttcttgaagatgac tacggcatggaattactagtagctggtaatataatttctctggatctgagcatttctcaa gtatacgagcaggtttggagaaagtcacataatcagactgcaagcaatctggttggttct ggtggcttcaatagtaccagtacaagagacaccccaccgatgacagtgacataccgactt caggggctggatggtgaagccactgagccaatgattaaggaattggaggaagaaagagag gaatctcaggatcctgaaattgaatttgcaatagctggtgcagttcaggaatgcgggggt cttgaaattattttgggcatgatccagcatctgcgggatgatgagttgaagtctaaccaa gaggaattgggatctgtgctgaatctcctgatgtattgctgcaagatacgggagaataga cgggctttgttgcgtttaggggctcttggacttctgcttgaaacagcaaggcgggccttt tcagtagatgccatggaacctgctgaaggcatcctcctaattgtcgaaagtttgacaatg gaagccaacgaaagtgatattggcattactcagagtgtactagtgacagatgatgaaact ggggctggtgaacaggcgaagaaaattgtcctcatgttcttggaaaggctttgtcaccct tttggtctcaagaagttaaataaacagcagagaaacaacgaaatggtggcaagaatcttg ccatatttgacttatggacaaactgctgccatggaggccctcattctgcactttgaccct tacttgcaggattggagtgaatttgatagggtacagaaacaacacctggaaaatccaaag gatgaaagtttggccgaacaagctgccaagcagaggtttgcactggagaattttgtgagg gtctcagagtcactgaagacaagctcctgtggggagagactgaaagacattatcttagag aagggcataactgcagttgctgtcagacatttgagtgagagctttgcatgtgctgggcaa gctgggtttaagaccagtgtagagtgggcttttggattgaagcttccatcagtaccacta atcttgtcaatgcttagggggctctcaatgggacattcggcaacccagagatgtattgat gatggagggatcttaccattgcttcatacactggaaggggtctcggtagaaaatgagata ggtgccagggctgagaacttgttagacacactgtctgacaaggagggtaaaggggatggg tttcttggagaaaaagtgcatatgttgcggcatgcaactaaggatgagaagcggcggcag gctctgagaaagagggaagaattgcttcaggggctcggaatgagacaagaagtagcttct gatggaggggagagaattgttgtttcacgacctattattgaaggtctggaagatgtggaa gaggaggaggatgggctagcctgcatggtttgccgtgaagggtacagtttacgtccaaac gacatgttaggagtttactcttacagcaagagagtgaatcttggcgtcggtacctcgggc agttctcgaggggagtgtgtttacacaactgtgagccatttcaacatcattcattttcag tgccatcaagaagctaagcgtgctgatgctgctctgaagattccgaagaaagaatgggag ggagctacattaagaaacaatgaaaccctctgcaactgtatatttcccttgaagggtcca tctgttcctttggcgcagtatgttcgttgtgttgatcagtactgggacaatctaaatgcc ctaggacgtgctgatgggagccgtctccggttgctgacatatgatgttgtgctgatgtta gccaggtttgcgaccggtgcttcttttagcacagattgcaatggtggaggaagggaaagc aattcacggtttctgccctttatgattcagatggctcggcacctgctcgaccaaggaggc tcaaaccaacggaaagcaatggcaaaatccataacctcatacttatcctctgtctctcct tctgatcccaagccttctgcatcctctggtactcggggtactaatggaacagaagaaact gttcagtatatgatggttaactctctcctctctgaatcctacgaagaatggctgcagcac cgtcgtggctttttgcagcgggggatttaccatgcttacatgcaacactcccatggtcga atgacccctctacgactctctgatccaactgctgttgtccgatcagaaggttctttgtca gattctagtgatgagactaacctctttcagattattttaccgatgcttgtctacacaggc ttgatcgagcagcttcagaaattcttcaaggtgaacaaagctgggaatttggctcagggt agaactggaggaactaacacagaatctgagggggatgaacggtgggaagttgcaatgaaa gaaagattggtgaatgtgaaggagatggttgggttctcaaaagaacttttatcatggctc gaggatatggcctccgcgtcggacttgcaggaagcatttgatgtgatgggggccttgggt gaggttctctcaggtggttttacacattgcgaagagtttgtgcagtcggctatcggcatg ggtaatgcaaaccgatga

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