Acanthamoeba castellanii: ACA1_065770 Help Entry ACA1_065770       CDS       T02667                                  Name (RefSeq) phosphatidylinositol 3kinase   KO K00922   phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153] Organism acan  Acanthamoeba castellanii Pathway acan00562   Inositol phosphate metabolism acan01100   Metabolic pathways acan04070   Phosphatidylinositol signaling system acan04081   Hormone signaling acan04620   Toll-like receptor signaling pathway acan05100   Bacterial invasion of epithelial cells Brite KEGG Orthology (KO) [BR:acan00001]  09100 Metabolism   09101 Carbohydrate metabolism    00562 Inositol phosphate metabolism     ACA1_065770  09130 Environmental Information Processing   09132 Signal transduction    04070 Phosphatidylinositol signaling system     ACA1_065770   09133 Signaling molecules and interaction    04081 Hormone signaling     ACA1_065770  09150 Organismal Systems   09151 Immune system    04620 Toll-like receptor signaling pathway     ACA1_065770  09160 Human Diseases   09171 Infectious disease: bacterial    05100 Bacterial invasion of epithelial cells     ACA1_065770  09180 Brite Hierarchies   09182 Protein families: genetic information processing    04131 Membrane trafficking [BR:acan04131]     ACA1_065770 Enzymes [BR:acan01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.1  Phosphotransferases with an alcohol group as acceptor     2.7.1.153  phosphatidylinositol-4,5-bisphosphate 3-kinase      ACA1_065770 Membrane trafficking [BR:acan04131]  Endocytosis   Rab GTPases and associated proteins    Rab associated proteins     ACA1_065770 BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  PI3_PI4_kinase PH PI3Ka PI3K_C2 PI3K_rbd PH_11 PH_8 PH_9 DUF4135 Motif Other DBs NCBI-GeneID:  14917986 NCBI-ProteinID:  XP_004339770 UniProt:  L8GXT7 LinkDB All DBs Position Unknown AA seq 1982 aa AA seqDB search MNFLRGNRSDTSQFCKLRVILLLPKSHDEDGESAPHHGGLPAWPPSSSPSPPSSASPSPP SPSSSTGLLQRHDFGAAGLNSKGTYDCEFPPKLSVEQIKANLFSTIPALFPLSRNDFYLA LAKEMVLYEEEKRLVASHEVVAEKFFNKERITVFLLPKDECPPPPQTDNSALPEEKEMER LAKEIERDESVWSTREIIVRAPSNLPCVPTHGISVDVWEQGESGLSPATPSPTTGSRSIF QRKKPLAMSVDEQRSAGTAAAMAASKALRGEIAEKPEKVRRGSVFSRRRRNKELNDQKNS ERLAGEYAGRFMSSSRSYDDLSRPREYSLDSGDTGSREASLDADDLAYGKQGADVFMSGY LVKQGGNRKNWKKRFCVLTADSIRYYGKKKDPTPIAAIPLDEIMAIARAFSLIRLFWTLA RKTHSCLTTQTRRRTYYMCAPNEEDLLAWMHATKLQLIERRKVMQEEEETGAGIEGWLTV WVVVSPGNEANLGRGFSLRGRWKRYWCFISNSDHCLYYVKDPSTKDKREGNFPLQGVTVE FSQQRRFCFSLKSQQKVLLLSADSEREMEEWMNAISQQPVDWEGRKTVQLQVLMPQGIVQ KLDRLTLVQTANVLDVLSRIPPEEPEVLFFRKMMLITQREARQFDSLMINHFLPARLVPA ALAASASDSASSPSPFSIPSPSSSSSSSSSSSSSSFLPATPSSPRGVAVGGGFSFAAPAS TGSVAVPSPATGGTAHSDLMSSGFLTRTNSLPNLQYSSHHRSGGGGLGGQPSGSDLIATA ATGLPSSSSSSLSTAHTAVAMSTSLSSVRTISGGGRKLNLYFHFFDVDSRQPAAPTPSER GGGSSGGASGDDDAAAGSESTELTTPPVRRNGDVSAGFGYRRFNTEMLVSRQNTPLPPPP VASRNGRAFLRTATGGSASDSDAAAASPDGADSSSSGSTQPAQKKPATSLVESLKFERPG RRSLEVMGEEVIGDQPASPRATNPSASSSVPAIRRRPSDAAARGSNNMLSASHRNFSPHT KLSLAINPDATIATAIAEVMSKYQRIYKKKQPSELEPESLDETKRAELGKFILQVKGRRE YVFDSNDTTIAQLAYVANCLAHWDKIEFVIRERSALSGHIDDKIKYYKERVKQTTPRSRK GEDSPQGTRSRRVAGRWNPATATATAGAGTVAAAPATSPPDSDAAVEVDTSDSAQDVGER ERQESNDDDEPSVEIVEHQCYDVDGLDDVPLVLKILGVEQQQAEIFDVNPNMSVSVECGL YYGPMQLGIYRTERMRKVNAWSDRPQVFHTHLPLSHIPKETRACFRLIAYQGKDEWAIGW GNVALFDHAGRFLTGGFEVHMWEGDRPSLMAPCVPNFGSGVESVMRIRASSISPPSLVPI AYTRPYTALAVSPAASVVPTSPALTDPACPSSEAFSDGFATPCAGSSPADPRSRFRADTV AAPVDGLAPFRTSSFDEEDFIDHEMQILKQIINQDIFYELSTEEKQMMWKHRDACIREHP RSLAKLLLSIDWLDRSAVRAFACRCLQNLSDEELAVYVPQLVQALKYDTYHHSALSQFLL SRGLRSRLIVGQRLFWEVKVASQIERNVKPKWDPNVASSPASSGASDEREVRGSGGEAMA LRYGLLAEAYLHGIGAQHREEIMKQVFVMEELLALSHALKKIPKNKRDAFLKYKLAQFPF PKDGITLPLEPRMQVKGFVVDKCKALDSFTVPLRLVFDNKEDVGDPITVIYKAGDDLRQD ALTLQLIRVMDTLWKDEGLDLRLTTYGVMATGEKEGIIEAVLNSTTVAEIAKEAGGATAV FNPQTISNWLKQQNPDDTKYAMAVENFIYSCAGYCVACYILGIGDRHNDNIMVTKTGHMF HIDFAHFLGNVLRFGPIVRDKAPFVLTPEMVYIMGGRESQQFQRFIRLCCRAYNVVRSHA NVFTNLFAMLSSKNDMNYLMKALAPEMTEEEAAKTFTGLIYKSLDTKTTQLNFAVHILAH RD NT seq 5949 nt NT seq  +upstreamnt  +downstreamnt atgaattttctgcgcggaaatcgatcggacacgtcccagttctgcaagctcagggtcatc ctcctgctccccaagtcccacgacgaagatggggagagcgctcctcatcacggggggctg ccggcctggcccccctcatcttcgccctcgcccccgtcgtctgcctcgccttccccgccc tcgccctcctcctccacgggcctgctacagcgccacgacttcggcgccgcggggctcaac agcaagggcacctacgactgcgagttccctcccaaactcagcgtcgagcaaatcaaggcc aacctcttcagcacgatcccagcgctgtttccgctctcgcgaaacgatttctatctggcc ctggccaaggaaatggtgctctacgaagaggagaagcggctggtggcgtctcacgaggtg gttgctgagaagttcttcaacaaggaacggataacggtgttccttctgccgaaggacgag tgtcccccgcctccgcaaacggacaacagcgccctccccgaggagaaggagatggagcga ctcgccaaggaaatcgagcgcgacgaatccgtgtggtccacccgagagatcatcgtgcgc gctccttccaatttgccgtgtgtgccgactcacggcatttcggtggatgtctgggaacag ggggagagtggtctcagcccagccactccctcgccgacgaccggcagccgaagcatcttc cagcgcaagaagccgctggcgatgagcgtggacgagcaacggagcgccggcactgcggcg gccatggccgccagcaaggccctgcgcggcgagatcgccgagaagcccgagaaggtgcgg cgcggcagcgtcttctcccgccgcagacgcaacaaggagctcaacgaccagaagaactcc gagcggcttgccggagaatacgccggtcggttcatgagcagttcgcgttcctacgatgac ctgagccgaccgcgcgagtactccctcgacagcggcgacaccggctcgcgagaggcctct ctcgatgcggacgatttggcgtacgggaagcagggggcggacgtgttcatgtcgggctac ctcgtcaagcagggcggcaaccgcaagaactggaagaagcgattctgcgtcctcaccgcc gattccatccgctactacggcaagaagaaggatcccactccgatcgctgcaattccattg gacgaaatcatggccatcgctcgcgcgttctctcttatccgcctcttctggaccctcgcc agaaagactcattcatgcctcacaacacaaaccagacggcgcacctactacatgtgcgcg cccaatgaagaggatctgctggcctggatgcacgccaccaaactgcagctcatcgagcgc aggaaagtcatgcaagaggaagaggagactggagcgggcatcgagggctggctcacggtc tgggtcgtcgtctcgcccggcaatgaggccaacctcggccgcgggttctccctgcggggc cgatggaaacggtactggtgcttcatctccaattccgaccactgcctctactacgtcaag gacccttccaccaaggacaagcgcgagggcaacttcccgctgcagggggtgacggtcgag ttctcgcaacagagacggttctgtttctccctcaaatcacagcaaaaggtgctcctgctc tcggccgacagtgagcgcgagatggaggagtggatgaacgcgatctctcagcaaccggtc gattgggaaggccgcaagaccgtccagctgcaggtcctcatgccccaaggcatcgttcaa aagttggatcggctcacgttggtgcagacggcgaacgttttggacgtgctctcccgcatc ccacccgaagaacccgaagtgctcttcttccgcaaaatgatgctcatcacccagagagaa gcgcgtcagttcgactcactgatgatcaaccatttcctccccgcgcgcctcgtgccggcc gcgctcgctgcctccgcctccgattccgcctcttctccctcacccttctccattccttca ccgtcttcctcctcttcttcttcgtcgtcatcttcgtcgtcttcgttcttgccggcgacg ccctcctcgccgcgcggcgtggccgtgggcggcggcttctcctttgccgcgcccgcaagt accggctcagtcgccgtgccgtcgcccgccaccggcgggactgcgcattcggacctcatg tcgtccggtttcctcacccgcaccaactcgctgcccaacctgcagtacagcagccaccac cgcagcggcggcggcggcttaggcggtcagccctcggggtcggacctcatcgccacggcg gccacggggctgccgtcttcgtcgtcgtcaagtctgtcgacagcccataccgcggttgcg atgtcgacatcactgtcgtcggtgcggaccatcagcggtggcggccgcaagctcaacctg tacttccacttctttgatgtcgacagccgccagccagccgcaccgacgcccagcgagcgc gggggcgggtctagcggaggcgcctcgggagacgatgacgctgcggccggcagcgagtcg acagaactgacgacaccgcccgtgcggcggaacggcgacgtcagcgcaggcttcggctac cgccggttcaacaccgagatgctggtctcgcgccagaacacgcctctgccacctccgccc gtggcctctcgcaacggtcgcgcgttcctgcggactgccacgggcggatccgcctcggac tcagacgccgccgccgcctcccccgacggcgcagacagcagcagcagcggcagcacccag cctgctcagaagaagcccgcgacgagcctcgtcgagagcctcaaattcgagcgacccggg cgtcgcagtctcgaagtcatgggtgaggaagtaatcggagaccagccggcgtcgccccga gcgaccaacccgtcggcgtcgtcgtcagtgccagccatccggcgccgacccagcgatgcc gcggcgcgaggcagcaacaacatgctctccgcgagccatcgcaacttctcgccacacacg aagctgtcgcttgcaatcaatcccgatgccaccatcgccaccgcaatcgcagaggtgatg agcaagtaccagcgcatctacaagaaaaaacagccgtccgagcttgagccggagtcgctg gacgagaccaagcgtgctgagctgggcaaattcatcctgcaagtgaaagggcgacgcgaa tacgtcttcgactcgaacgacaccacgatcgcgcagctggcgtacgtggccaactgtctg gcgcactgggacaagatcgagttcgtcattcgcgagaggtccgccctcagcggccacatc gatgacaagatcaagtactacaaggagcgggtgaagcaaacgactcctcgcagtcgcaag ggcgaggactcgccgcagggaacgcgcagccgccgagtggccggccgctggaacccggca acggcaacggcgaccgcaggggcaggcacagtcgctgccgcaccggccacgtccccgccc gactcggacgcggccgtggaggtggacacaagcgactctgcgcaggacgtcggtgagagg gaacgacaggagagcaacgacgacgacgagccctcggtggagatcgtcgagcatcagtgc tacgatgtcgacggccttgacgacgtgccgctggtgctcaagatcctgggcgtcgaacag cagcaggccgaaatcttcgacgtcaaccccaacatgtcggtctctgtcgagtgcggacta tattatggccccatgcagctgggcatctaccgaacggagcgcatgcgcaaggtgaacgcc tggtccgatcgcccgcaggtcttccacacccaccttcccctgtcgcacatccccaaggaa acgagagcgtgcttccgcttgatcgcctaccaaggcaaggacgagtgggccatcggttgg ggcaatgtggcgctgttcgaccatgccggcaggttcctcaccggcggcttcgaggtccac atgtgggaaggcgaccggccttcgctgatggcgccgtgtgtgcccaacttcggatcggga gtggagagcgtgatgcggatccgggcctcgtccatctccccgccctcgctcgtgcccatc gcctacacgcggccctacaccgccctcgccgtctccccggccgcctccgtcgtccccacg tcgccggcgctgaccgacccggcgtgtccgtcgtcggaggccttctccgacggctttgcc acgccgtgcgccggctcctccccggcggacccgcggtcccgcttccgggccgacaccgtc gcagcgcccgtcgatggcctcgcgcccttccgcacgtcgtcgttcgacgaggaggatttc atcgaccacgagatgcaaatcctcaaacagatcatcaaccaagatatcttctacgagctc agcacggaggagaagcagatgatgtggaagcaccgggacgcctgcatccgcgagcacccg cggtcgctggccaagctcctgctctccatcgactggctcgaccgctccgccgtgcgcgcc ttcgcctgccggtgcctccagaacctgtccgacgaagagctggccgtctacgtgccgcag ctcgtccaggccctcaaatacgacacctaccaccactcggccctctctcagttcctcctc tcccgagggctgcgttctcgattgattgtgggccagcgcctgttctgggaggtgaaggtg gcgagccagatcgagcgcaacgtcaagcccaagtgggatcccaacgtggcctcgtcgccc gccagcagcggagcctccgatgagcgcgaggtgcggggcagcggcggcgaagccatggcc ctgcgctacggactcctcgccgaggcctaccttcacggtattggagcgcagcacagggag gagatcatgaagcaggtgttcgtgatggaggagctgctggccctgtcgcacgcgctcaag aagatccccaagaacaagcgcgacgccttcctcaagtacaagctcgcccagttccccttc cccaaggacggcatcaccctgcccctcgagcctcgaatgcaggtgaagggcttcgttgtg gacaagtgcaaggcgctcgattccttcaccgttccgttgcggctggtgttcgacaacaag gaggacgtgggcgatccgatcacggtcatctacaaggccggcgacgacctgcgccaggac gccctcaccctccaactcatccgcgtcatggacaccctgtggaaggacgaagggttggac ctgcggctcaccacctatggtgtcatggccaccggcgagaaggagggcatcatcgaagct gtcctcaattcgaccaccgtcgccgagatcgccaaggaggccggaggggccacggcggtg ttcaacccgcagaccatctccaattggctcaagcaacagaaccccgacgacaccaagtac gccatggccgtagagaatttcatctactcgtgcgccggctactgcgtcgcatgctacatt ctcggcatcggcgatcggcacaacgacaacatcatggtgaccaagacgggccacatgttc cacatcgactttgcacactttctaggaaacgtgctcaggtttggaccgatcgtgcgggac aaggcgcccttcgtgttgactcccgagatggtgtacattatgggcggccgagagagccaa cagttccaacgcttcattcggctgtgctgccgcgcctacaatgtggtccgcagccatgcc aacgtcttcaccaacctcttcgccatgctgtcgtcaaagaacgacatgaactatctgatg aaggcgctggcaccggagatgaccgaagaggaggccgccaagaccttcacgggtctcatc tacaagagcctcgacaccaagaccacccaactcaattttgccgtacacatcctggcccac cgcgactag

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