Acanthamoeba castellanii: ACA1_131840
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Entry
ACA1_131840 CDS
T02667
Name
(RefSeq) HEAT repeat domain containing protein
KO
K04533
huntingtin
Organism
acan
Acanthamoeba castellanii
Brite
KEGG Orthology (KO) [BR:
acan00001
]
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03019 Messenger RNA biogenesis [BR:
acan03019
]
ACA1_131840
04131 Membrane trafficking [BR:
acan04131
]
ACA1_131840
03029 Mitochondrial biogenesis [BR:
acan03029
]
ACA1_131840
Messenger RNA biogenesis [BR:
acan03019
]
Eukaryotic type
mRNA surveillance and transport factors
mRNA cycle factors
Common to processing body (P body) and stress granule
ACA1_131840
Membrane trafficking [BR:
acan04131
]
Endocytosis
Rab GTPases and associated proteins
Rab associated proteins
ACA1_131840
Mitochondrial biogenesis [BR:
acan03029
]
Mitochondrial quality control factors
Regulator of mitochondrial biogenesis
Other regulator of mitochondrial biogenesis
ACA1_131840
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Htt_N-HEAT
Htt_C-HEAT
Htt_N-HEAT_1
HEAT
HEAT_GCN1
TPR_Trm732_C
CbiJ
HEAT_EZ
Motif
Other DBs
NCBI-GeneID:
14914744
NCBI-ProteinID:
XP_004336193
UniProt:
L8GM96
LinkDB
All DBs
Position
Unknown
AA seq
2966 aa
AA seq
DB search
MDLSLERALKILETPTAAAPETVEFRESRIKSCRLIAAHLCNLALRANTDFAAQLSRGIA
ALLHTCGDKDMSVWTVADETLNKVIKTLIASFQDRVLIALYKGIKGDELIQQTLSDSMDK
LCCTLVYYLREKEVNNIIELLVRNLADVSGAIRRASAASIVVICRHYPKSPFDFAIYTIR
KQLQSYIIPATKPDHQVSTPVGSPKVARAAPAITSPRKDSAVQNRAMSFMDDKDNKDDDD
INMDEEEKDGADNSRKEHEKEDEKASNEVKQPISEANLYGILYCLLQLLNLSEEWKSRVV
DPRNPILPHVPFLHDLASKCMVHYDQNVMGIALELLQAILAASHSPSRNAVLNSQLVSPT
TVPEILGRLTWILNRKPPVRVASRAVVLQCLSFLALHYTQTFCDYFRLTDGAEAATAVDD
LSKGDAAAAPADEAEAAADNGGSGVAQTTYAQNQHTMKELLQLVTFSDPLIRGSLAHIIA
CFIAGILRNPHTTATPAQATAATSPGAEESVPVPVLALEVIDVQSLIVDYLLRLLLDESA
NVRKMVCRALITCFDDILASAYARCAITILYTLIDSIREDTYWLVKTEALAFVASVDYCA
LQVVERDLATENRVFVYTREETSFQRRCLNMVLDLLASPDARVRQAAAEAVVTLVERLQL
YSPAGPTHPYAALIERHIRHLCTVHSIKKFAIRRDVLHNLSQVAQLLLERVNALVPEDGV
RGIYHALLLLCKAYAKPHTYLTHAHTEGMKNFDALPNPMAIYFGDFVPLIVERLTSSWAA
TDLDVHIDLVQIIGYMCKKSERHHLTSQWLRILQHLLAVITLLSHIAQRKPAPQSRPETA
SGFAMIADLAASPATKGAVLGTAATQGVYTELYEKLHSTFSTSLISFEQDKFSLLRKSCF
KAMAMLIRNVGRYVVPFAQEILNHLNVHFFLSPKEVMSCLLELFMVTFHPVQPSKAQVQR
VFHDANYKSHQAIVHPHNLGVYEQLYQGFDEEAAMAASLQDASKVPSLRPSLLSHPYRLR
ETQSEDFYSKVDLPIPLIEADKIIRSGKSLIRMFEPLVIGAMKLYRDTHDLGLQKQVLFV
MTQLIKFGIDFSRLDKDQSFLGHVINQIMGKKSYLPHPPHILPYIFDFLSVLAIIRKHLP
GLAVLGELWHVAAHYRQTTTKWTEEDCEKELTELREEFLARILKRANLSHGIGLLSIILF
KSRYRVEECKGYALKIGQTLFPLLASASLAANIATNDYELLELYALFDKVVEKHSESEKT
KKETTDSLCEGFVQLSIKSVTGPYWLPPALVYLRFLGMRSEEEILPALAKLDDDPASSSP
GEDVFVRRMMELVLIALQDTMKREHASAFSVELYAHLVTHLIALASPARFPRIHAAMRGL
WTDAATDFAHARLFPLLFSGPLAYGREVACLSLAMLKFARSSRTAAGRGKLGWRARVVEL
TALVGYLATFLDASASHAWSGLTWSEDLGQLLIEHTNEPTVKKFVALVGSALSSPSMYAT
ASGRFAFQLLGSLRSRLLGSGSAAGRQEQDFKNLLAALGSLPPSMATVGVLLRVLKRRGR
SLFAERLLLAQLTSEISYVLSSTRIYFILQGIDGQPQREAKLRRQVTKARRRFDALGFPE
TAPLTVAFGRFVAAALELLPSGDSDNAADADADVTIGFSARQQRERDNTADVRQRLHGDN
WKQLIVEFAMERCTAAVNGEAGEADVATADHLASGLKAIYYADKPAFLALLRRTTPKLQS
THSDADGAEEEPACDLGLLAHLVLTSKPIMRDASVRKAVIALITAHIKSVIAADAADAPE
PAWHDFVQVVRSVVCVLQCDGRPSRSVVAAAMSSSSSATSAATGPAGTSSPNGSSASLLT
SSSAALLAHVASLSEALYQHLTELDMPRPPPPGKTAASEDDLVVVLKCTELVIAISQRET
LTEWQSDDEKATWEHMFASILQVQELISGKSVSVAADEEWHDGERRRAEIKMERVMELLL
SEADNKRFAYLHDTCADNPVVNAYCDLVTALARKDVQLIYPQIVEGAYLEYDLLQNINNM
HDSSRQKFDENPEKILAITLRLLNAVTWDHNSQFTKLWANLLAMFDVNKVNEEWCSLKTQ
SLLARSLTSLLMRSCLGIATLPETTTSPTPLSGWYYWRSVGTMAWDAYSLVHVPRERELI
YLNSENGRTLVSLQSALAAAVSKLHSPSAASLDSWQFPTPPSANTALQSSSLVQLSPYHQ
NIERIGWPSLRYYAGQVSVHELRQNRQYKWQGIDMTNLVDVLLRSFEKRLASEPGSMMAA
EAMRGILILSDLFRTDQWRWMCQLFIRMLEEDQVDDQVQHYYLLAGIARALAVSERDCLG
LVTPMWVTNTFRHALESAHQSARLAALNALLTLIEGNLTRVLLPLLPYFFKTILAALCEE
GGGQWLGTAREQAHLIGVAFLLIEQYPKESEEQDFTRRALAQMIKTGENSDDKMMLSAIF
RGFDRLLISFSLSHTHRKRLAKFAMSKIHSFVGQGDGELFLYSLGLMLTVMYTERDSKPS
KPHPATSPTDRESRNEVRNIERVTILFSKLPSSSSFETQAVIKVLPRVLVDFFRVEQALT
LVIGEFVKAVAKGAPSPVTHVLYKGHKQTLAQWILICAPNFTNIRQVTRSTWGLACLFLP
LASERALRALFADVARMGYVPMDLFLLIAFHFFTLLIAEEPFPSLLHVCGAEVKRLRSLS
SDDDADADAEPTSADRSAANLSPRRALSTSALPPVQSLNDLGSEERDLHHSHHSHSGRRR
GASPPLPKDRLSEKRIRERFYARMRRGGPDAGSSGSGSEGEVSPQLPYDHHRSSRREKSY
DEAALQRIKHLADRQDAEARGDADGAGGDGSNERRRELSFDEAAQGRRRLVAEEEKEARS
SPSVRRQLLPTTATGSLTPNKPKKKRRASQSKKDKTSSSSSSSSAGDDDVDGRREKAEEE
DEEKQRPKEEDTDDHHNHHNHNDASA
NT seq
8901 nt
NT seq
+upstream
nt +downstream
nt
atggatttgtcgctcgagcgggcgctcaagatcctcgagacgcccacggctgcggcccct
gagacggtcgagttccgcgagagcaggatcaagagctgccgactcatcgccgcccatctg
tgcaaccttgcccttcgggcgaataccgactttgcagcgcagctgtcgcgtggcatcgct
gccctcctgcacacatgcggcgacaaggacatgtccgtgtggacggtcgctgacgagacc
ctcaacaaggtcatcaagaccctgatcgcctccttccaagaccgagttctgattgcgctc
tacaaaggcatcaaaggcgatgagttgatccagcagacgctgagcgactcgatggacaag
ctctgctgcacgctggtctactatctgcgcgagaaggaggtcaacaacatcatcgaactc
ctggtccgcaacctcgccgacgtgtctggagcgattcggcgcgcatcggcggcttcgatt
gtggtcatctgccgccactaccctaagtcgccgttcgactttgccatctacaccattcgc
aagcagctccagtcctacatcatccccgcaaccaaacccgaccatcaggtgtcgacgccc
gtgggctcgcccaaggtggcgcgcgctgcgccggcgatcacgtcgccgcgcaaggattcg
gcggtgcagaatcgggcgatgtcgttcatggacgacaaggacaacaaggacgacgacgac
atcaacatggacgaagaggaaaaggacggcgccgacaactcccgcaaggagcacgagaag
gaggacgaaaaggcttcaaacgaagtgaaacagccgatatcggaggccaacctgtacggc
atcctgtactgcctgctgcagctgctcaacctctccgaagagtggaagagccgagtcgtg
gatccgcgcaaccccattctcccgcatgtgcccttcctacacgacctggcctccaaatgt
atggtccattacgaccagaacgtgatgggcatcgcgttggagctcctccaggccattctg
gcagcctcgcacagtccctcgcgcaatgccgttctcaactcgcagctcgtatctcccacg
accgtgcctgagatcctgggccgacttacgtggatcctcaaccgcaagcctcccgttcga
gtggcctcgcgcgcggtggtgctccagtgcctgtcgttcctggccctccactacacccag
accttctgcgactacttccggctcaccgacggcgccgaggccgccaccgccgtcgatgat
ctctccaagggcgacgccgcggcggcaccggccgatgaagccgaggctgcagctgacaac
ggcggcagcggcgtcgcgcagaccacctacgcgcagaaccagcacacgatgaaggagctg
ctgcagctggtgaccttctccgatccgctgatccgcggcagcctcgcccacatcatcgcc
tgcttcatcgctggcattcttcgcaatccgcacaccacggcgacacccgcacaagcgacg
gcggcaacgagtccgggcgcggaggagtcggtgccggtgccggtgcttgccctcgaggtg
atcgacgtgcagtcgctcatcgttgactacctgctccggctgctgctcgacgagtccgcc
aacgtgcgcaaaatggtgtgtcgcgcgctcatcacgtgcttcgacgacatcctcgcctcg
gcgtatgcgcgctgcgcaatcacgatcctctacaccctcatcgacagcatccgtgaggac
acctattggctcgtcaagaccgaggcgctggcctttgtggcgagtgtggactactgcgcg
cttcaggtggtcgagcgagacctggccacggaaaaccgggtcttcgtctacactcgcgag
gagacgtcgttccagcggcgctgcctcaacatggtcctcgacctactcgccagccccgac
gctcgcgtgcgccaggctgcggctgaggctgtggtgacgctcgtggagaggcttcagttg
tactcgcccgccgggcctacgcacccctacgctgcgctcatcgaacgccacattcgccac
ctgtgcaccgtccactccatcaagaagttcgcgattcggagggacgtgctgcataatttg
tcgcaggtggcgcagctcctgttggagcgggtgaacgcgctggtgccggaggacggcgtg
cgaggaatctaccacgcgctgctgctcctctgcaaggcctacgccaagcctcacacctac
ttgacccacgcccacactgaggggatgaagaactttgatgcgctgcccaacccgatggcc
atctactttggcgacttcgtcccgctgatcgtcgaacggctcacgtcgtcatgggctgcc
actgatctcgacgtacacatcgacctcgtccagatcatcggctacatgtgcaagaaatcg
gagcgacatcacctcacctcgcagtggctgcgcatcctgcaacacctgctcgcggtgatc
accctcctcagccacatcgcccagcgcaagccggcaccccagtccagacccgaaactgcc
tcgggctttgccatgatcgccgacctcgccgcatcgccggcgaccaagggcgcagtgctg
ggaacggccgcgacccagggcgtctacaccgaactctacgaaaagctgcacagcaccttc
tccacctccctgatctccttcgagcaggacaagttctccctcctccgcaagtcctgcttc
aaggcgatggccatgctgatcaggaacgtgggacgctacgtggtgcccttcgcccaggaa
atcctcaaccaccttaacgtccacttcttcctctccccgaaggaggtgatgtcgtgcttg
ttggagctgttcatggtcacgttccaccccgtgcaaccgtccaaggcccaagtccaacgc
gtcttccacgacgccaactacaaatcccaccaggccatcgtccacccgcacaacttgggt
gtctacgagcagctgtaccagggcttcgatgaggaagcggcgatggcggcctcgctgcag
gacgcctccaaggttccgtccctgcggccttccctcctgtcgcacccctatcgactccgc
gagacccagtcggaggacttctacagcaaggtggacctccccattcccctgatcgaggcc
gacaaaatcatccggagcggcaagtcgctgatccgcatgttcgagccgctggtgatcggc
gccatgaagctgtacagagacacgcacgatctcggcctgcagaaacaggtcctcttcgtc
atgacgcagctcatcaagttcgggattgacttttcgcggctcgacaaggaccagtcgttc
ctgggtcacgtcatcaatcaaatcatgggcaagaagtcctacctcccgcacccgccgcac
atcctgccctacatattcgacttcctctccgtgctcgccatcatccgcaaacacctgccc
gggctcgccgtactgggcgagctctggcacgttgctgcccactatcgccagacgacgacc
aagtggaccgaggaggactgcgagaaggagctcacggaactgcgcgaggaatttctggca
cgcatcctcaagcgggccaacctgagccacggcatcgggcttctgtcgatcatactcttc
aagagccgctaccgcgtcgaagagtgcaaggggtatgcgctcaagatcggacagaccctc
ttccctctgttggcctccgcgtcgctcgcggccaacattgccaccaacgactatgaattg
ctggagctctacgccctgttcgacaaggtcgtggagaagcacagcgaatcggagaagacg
aagaaagaaaccaccgactcgctttgcgaaggcttcgtgcaattgtccatcaaatccgtg
accggcccctattggttgccgccggcccttgtgtatttgcgcttcctgggcatgcggagc
gaagaggaaatcctgccggccctggctaagctcgacgacgacccagcgagctcaagcccc
ggcgaggatgtcttcgtccgtcgcatgatggagctcgtcctcatcgccctccaggacacg
atgaagcgagagcatgcgtcggcgttcagtgtcgagctctacgcgcatctggtgacccac
ctgatcgccctcgcctcgcccgcgcgctttccgcgcatacacgcggccatgcgcgggctg
tggacggacgccgccaccgactttgcccacgcgaggctcttcccgctcctcttcagcgga
cccctcgcctacggccgcgaagtggcctgcttgtcgctggcgatgctcaagttcgcgcgc
tcgtcgcgcacggccgctggtcgtggcaagctgggctggcgggcgcgcgtggtggagctc
acggcgctcgtgggctacctcgccacattcttggacgcgagcgccagccacgcctggtcg
ggactcacctggagcgaagacctcggccagttgctcatagagcacacgaacgagccgacg
gtgaagaagttcgtggcgttggtgggcagcgccctgtcgtcgccgtccatgtacgccacg
gcctcgggccggttcgccttccagctgctcggcagcctgcgcagccgactgctcgggagc
ggcagcgcagccggtcgccaggagcaggacttcaagaacctcctcgccgctctcggcagc
ttgccgccgtccatggccactgtcggggtcctgttgcgcgtgctgaagcgtcgcggtcgg
tccctgttcgccgagcggctgctcttggctcaactgacgtcggagatctcctacgtgctc
tccagcacccgcatctacttcattctccaaggcattgacggtcagccccagcgcgaggcc
aagctgcggcgacaggtcaccaaggctcgccggcggttcgacgccctgggcttccccgag
accgcgccactaacggtggcctttggccgcttcgtcgccgcagcgctcgagctgctgccc
agcggcgacagcgacaatgcggccgacgccgacgctgacgtaacgatcggcttctcggcg
cgccagcagcgggagcgcgacaacacggccgacgtccgacagcgcctgcacggcgacaac
tggaagcagctgatcgtcgagttcgcaatggagcgctgtactgcggcggtcaacggcgag
gccggcgaggccgacgtggcgacggcggaccacctggcgtcgggcctcaaggccatctac
tacgccgacaagccggcattcctcgcattgctcaggcgcacgacgccgaagctgcagtcc
acacacagcgacgccgacggcgccgaggaagagccggcgtgcgacctgggtctgctggcg
cacctggtgctgacgtcgaagccgatcatgcgcgacgccagcgtgcgcaaggccgtcatc
gccctcatcacggcccacatcaagtccgtcatcgccgccgacgccgccgacgcccctgag
ccggcgtggcacgactttgtgcaggtggtcaggtccgtggtgtgcgtccttcagtgcgac
ggccgcccatcgcgcagcgtcgtggcggctgccatgtcatcgtcgtcgtcggccacgtca
gcagcaacgggacccgcgggaacgtcgtcgcccaacggctcgtccgcatcgctgctgacg
tcatcatcggccgcgctgctggcccacgtggcctcgctgtccgaggccctctaccagcac
ctcaccgagctcgacatgccccgccccccgccgccgggcaagacggcggcgtcggaggac
gacctggtggtggtgctcaagtgcaccgagctcgtcatcgccatcagccagcgcgagacc
ctgaccgagtggcagtccgacgatgagaaggccacctgggagcacatgttcgccagcatc
ctccaggtgcaagagctgatttcgggcaagtcggtgagtgtggcggccgacgaagagtgg
cacgacggcgagcggcggcgcgcggagatcaagatggagcgggtgatggagctgctgctg
tcggaggccgacaacaagcggttcgcctacctccacgacacgtgcgccgacaacccggtg
gtcaacgcctactgcgacctcgtcaccgccctcgcccgcaaggacgtccaactcatctac
ccacagatcgtcgaaggcgcctatttggagtacgacctgctgcagaacatcaacaacatg
cacgacagcagccggcagaagttcgatgagaatccggagaagattctggccatcacgctg
cgcctgctcaacgccgtcacctgggaccacaactcgcagttcaccaaactctgggccaac
ctgctggcaatgttcgacgtcaacaaggtcaacgaggagtggtgcagtctgaagacgcag
tccctgctggctcgttccctgacgtcactcctcatgcgatcctgcctcggcatcgccacc
ttgcccgagacgacgacttcgccaacgccgctgagcgggtggtactactggcgctcggtg
ggcacgatggcgtgggacgcctactcgctggtccacgtgccgcgcgagcgcgagctgatc
tacctcaacagcgagaacggccgcacgctggtgagcctgcagagcgcgctggccgcggcc
gtgtcgaagctgcactcgcccagcgccgcgtcgctcgactcgtggcagttcccgacgccg
ccctcggccaacacggccctgcagagcagcagcctcgtccagctctcgccctaccaccag
aacatcgagcgcatcggctggccttcgctgcgctactacgccgggcaagtgtcggtccac
gagctgcgacagaacagacaatacaagtggcagggcatcgacatgaccaacctggtggac
gtgctgctgcggtcgttcgagaagaggctcgcctcggagcccggatccatgatggccgcc
gaggcgatgcgcggcatcctcatcctctccgacctcttccgcaccgaccaatggcgctgg
atgtgccaactcttcattcgcatgctcgaggaggaccaagtggacgaccaggtgcagcac
tactacctgctggcgggtattgcgagggcgctggcggtgagcgagcgcgactgcctgggc
ctggtgacgcccatgtgggtgaccaacacgttccgccacgcgctcgagagcgcccaccag
tccgcgcggctcgccgcgctcaacgccctgctcacactcatcgaaggcaatctcactcgc
gtgttgctgccgctactgccatacttcttcaagacgatcctcgcggccctctgcgaagaa
ggcggcgggcagtggctgggaacggcgcgggagcaggcgcacctgatcggggtggcgttc
ctgctgatcgagcagtaccccaaggagtccgaggagcaggacttcacccgccgcgcgctc
gcccagatgatcaagaccggcgaaaactcggacgacaaaatgatgttgagcgcgatattt
aggggctttgatcgtctgttgatctccttctccctgtcacacacgcaccgcaaacgcctc
gccaagtttgccatgagcaagatccactcgttcgtggggcagggcgacggtgagctgttc
ctgtattcgctgggcctcatgctgaccgtcatgtacaccgagcgcgacagcaagccctcc
aagccccaccccgccacctcgcccaccgaccgtgagagccgaaatgaggtgaggaacatc
gagcgggtgaccatcctcttctccaagctgcccagctcgtcttccttcgagacgcaggcc
gtcatcaaggtgctgccgcgagtgttggtggacttcttccgcgtggagcaggcgctgacg
ctggtcatcggcgagttcgtcaaggccgtggccaaaggcgcaccctcgcccgtcacccac
gtcctctacaaggggcacaagcagacgctggcgcagtggatcctgatctgtgcgcccaac
ttcaccaacatccgccaggtcacgcggtcgacctggggcctcgcctgcctcttcctgccc
ctggccagtgagcgagcactgcgcgcgctgtttgctgacgtggcacgaatgggctacgtg
cccatggacctcttcctgctcatcgccttccacttcttcaccctcctgatcgccgaagag
ccgttcccgtcgctcctccacgtgtgcggcgccgaggtcaagcgcctccggtccctgtca
tcggacgacgacgccgacgccgacgccgagccgaccagcgctgatcgatccgccgccaac
ctgtcgccgcgccgggcgctgtcaacgtcggcgctgccgcccgtccagtcgctcaacgac
ctgggctcggaggagcgcgacctgcaccacagccaccacagccacagcggccgccggcgc
ggggccagcccgccgctgcccaaggaccggctcagcgagaagcgcatccgcgagcggttc
tacgcccgcatgcgccgcggcggacccgacgccggcagcagcgggagcgggagcgagggc
gaggtgtcgccgcagctgccctacgaccaccaccggtcgtcgcgccgcgagaagagctac
gacgaggccgcgctgcagcgcatcaagcacctggccgaccggcaggacgccgaggcgcgc
ggcgacgccgacggtgcgggcggcgatgggagcaatgaaaggcgccgcgagctgagcttc
gacgaggcggcgcaggggaggcgaaggctggtggccgaggaggagaaggaggcgaggtcg
agcccgagtgtgcggcgccagctgctgccgacgacggcgacggggtcgctgacgccgaac
aagccgaagaagaagcggcgggcctcgcagtccaagaaggacaagacctcgtcgtcatcg
tcttcttcttcggctggcgatgatgatgtcgatggcagacgagagaaggcagaggaggag
gacgaggagaagcagcggcccaaggaggaggacactgatgaccaccacaaccaccacaac
cacaacgacgcgtctgcctga
DBGET
integrated database retrieval system
