KEGG   Acanthamoeba castellanii: ACA1_181940
Entry
ACA1_181940       CDS       T02667                                 
Name
(RefSeq) phosphoinositide 3kinase family, accessory domain (pik domain) domain containing protein
  KO
K00922  phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
Organism
acan  Acanthamoeba castellanii
Pathway
acan00562  Inositol phosphate metabolism
acan01100  Metabolic pathways
acan04070  Phosphatidylinositol signaling system
acan04081  Hormone signaling
acan04620  Toll-like receptor signaling pathway
acan05100  Bacterial invasion of epithelial cells
Brite
KEGG Orthology (KO) [BR:acan00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    ACA1_181940
 09130 Environmental Information Processing
  09132 Signal transduction
   04070 Phosphatidylinositol signaling system
    ACA1_181940
  09133 Signaling molecules and interaction
   04081 Hormone signaling
    ACA1_181940
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    ACA1_181940
 09160 Human Diseases
  09171 Infectious disease: bacterial
   05100 Bacterial invasion of epithelial cells
    ACA1_181940
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:acan04131]
    ACA1_181940
Enzymes [BR:acan01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.1  Phosphotransferases with an alcohol group as acceptor
    2.7.1.153  phosphatidylinositol-4,5-bisphosphate 3-kinase
     ACA1_181940
Membrane trafficking [BR:acan04131]
 Endocytosis
  Rab GTPases and associated proteins
   Rab associated proteins
    ACA1_181940
SSDB
Motif
Pfam: PI3_PI4_kinase PI3Ka PI3K_C2 PI3K_rbd SDH_C
Other DBs
NCBI-GeneID: 14922169
NCBI-ProteinID: XP_004345837
UniProt: L8H982
LinkDB
Position
Unknown
AA seq 1732 aa
MSSQSEEEKEIRRRKVEELMRKHEMKEKGGLSSSPSRTSDRQQKQPSLQNNAYASVAQPP
ITTQSAKATDAPPKSAAVAPHSSSNGENGSQATIDLDVDVDDVERILEKAARLLRDEEDR
KVRNSIRLTSSPLSSSTSSSSSSSSSLSASSAAPQAATPAAAAAPPTAAASPAAAAVPPT
PAPTPVVPPQEQTHVVQKEEQEQGGEEQEEEQTKKIKKKKKKKTSPRDENGYDKASSPER
KKKKKKKRKGSNDSNGSNESNDGGVAAPQPAATAAEEEVVAQTASAAEALAKVAEEPERQ
PVEQMMPESNDSAGALSTSKDEEEAEEEAEAEEAEGGSSSSESSFEDNNNSLSPLTSPTS
MSNEAEATTELGGPSSPDCIDDPDAVRHRATAWQKANFVAAKPSEQARRTVARPHSGGYG
RTTRAFLGNRSSEPGSPAGGAQPSTPPAGHPALKLYRSVESGSSERTNNDDEAEDAIKDR
KSVYSMQLPTSSSGGGSEVSQAINASLARKWGAARRSGPVHTSFQDLMRLRSSSVIGNDF
TGSGSLPVTTGSHTMTNKNDEYVIKFVHDDELFRIVCSCEMNASQIKAAMIQHVKAFLGI
PDSDPKGKDKEDSESESESKSRPSSSSILSSSSSSSSSLSSSSSSSSSPRTSTSSPPPLG
QSLDEKDYVLKIPGVNYYLVKEEQSLHLVGVLQVCKKSFVSFPLEMIPRPSTDVLHENDK
LNVREKIMSELNANTEVFELLSNPISGDNPLLQILKSDNDEINSFRKRITKVRRAVLKER
EALVRQLSEAHSNSKYDTSFLPQYRESEPLPLNLPNSFIILAYQPADEKDEVQTSTQKFS
VTRNQTVAELKSNMFRKYKGTHPLATGTEEDYIVKVTGFKEYMIGSHKILSYDYIRKCLS
KKVTPILSLVPLKDVDLMIPEPVEDSVVDMILSREKNVHMSKLRYKDQEPRKPISEMVQQ
LRVKINGVDNVDTFNHIIKSWMREQKGKKEHKEQKGSLIDDKDGGKKKTYCLYVCAQIYH
GDELIADDMYTNAILYSNGPLWNEWLVSSVKLRDIPRGSRMCFTLYRRQLDNTVSAEAVF
TEKGRFNEKTDVPLGWVNFQFIDHKDQLRQGLCSFKLWLGKPNPIGTCVENVAVKDKERA
TTLHVEFQIHRTAVYFPPPPTVNPADAAAAARGSSQPAPAPSSADASKQKIIKLQLEEIM
KKGYELRLCSSATAALVGHPLTALGEDERQLLWECREFCAQFPSLLPRFLQYVKWNDRES
VLEAYRMLALWSPPTPFEALSLLDAKYASPVVRAYAVKRLHELDDRALSDFLLQLTQVLK
YEAYHYSPLAEFLLSRALMNVNQIGHAFFWLLKSELHNPTIASRYSLLAEAYLRGCGAHR
QELVKQNKVLNQLAKVAMRVKEAPSSSEKKKVLEDGLRRMEFPARFQLPLDPRQEVKGVI
VDKCKYMDSKKQPLWLVFENAEKRGAPIRVIFKAGDDLRQDVLTLQMLRIMDKLWKEEGL
DLRLNPYGCVATGDELGMIEVVLNASTTASVNKEKGGSKAVLYKDTLTSWLKEKNPSAEA
FEAAQENFMLSCAGYCVATYVLGIGDRHNDNIMITQFGHLFHIDFGHFLGNVKSKLGIKR
ERAPFIFNPQFAHVLGGSQGTRYAQYVETCQRAYNIVRKHAHMFINLFMMMLSTGIPELQ
CEEDILYLCGSLLVGTEEKAAAENFAKLIEEARKTKSVLVNDIVHIWAHSKK
NT seq 5199 nt   +upstreamnt  +downstreamnt
atgagcagtcaaagcgaagaggagaaggagatccgccggcgcaaggtggaggaactcatg
cgcaaacacgaaatgaaagagaagggtggcctgtcgtcgagcccgtcgcggaccagcgat
cgacagcaaaagcagccctccctccaaaacaatgcctacgcatctgtcgcgcaacctccc
atcaccacgcaatctgccaaggcgactgatgcgccgcctaaaagtgctgcggtagctccc
cattcatcgtcaaacggcgaaaatggcagccaagccaccatcgacctcgacgtggacgtg
gatgatgtggagcgcatcttggagaaggctgcccgcctgctgcgcgatgaggaagatagg
aaggtgaggaattccatacggctcacatcttctccgctttcctcctctacttcgtcatca
tcttcatcttcatcttctttatctgcttcatctgccgccccgcaggcggccactcctgcc
gcggctgccgcccctcctactgctgcagcttcgccagccgccgctgcggtccctcctacg
cctgcacccacccccgtcgttccgcctcaggagcagacgcacgtcgtacaaaaggaggag
caggagcaggggggagaggagcaggaagaggagcaaacgaagaagatcaagaagaagaaa
aagaagaagacttcgcctcgagacgagaacggctacgacaaagcatcgtctcccgagcgc
aagaagaagaaaaagaagaagaggaagggcagcaatgacagcaacggtagcaacgagagc
aacgacggcggcgtcgccgctccgcagccagcagcaacagcagcggaggaggaggtcgta
gcgcagaccgcgtctgccgccgaggccttggcgaaggtggcggaggaaccagaacgccag
cccgtggagcagatgatgcccgagtcgaacgacagcgccggagccctcagcacgagcaag
gacgaggaagaggcggaagaggaggcggaagcggaagaggcggaaggcggcagcagcagc
tctgagtcgagcttcgaggacaacaacaacagcctgtcgccgctcacgtcgccgacgtcg
atgtcgaacgaggccgaggccaccaccgagctcgggggtccgtcgtcgccggactgcatc
gacgatcctgacgctgtgaggcaccgcgccacggcgtggcagaaggccaacttcgtggcc
gccaagccgtccgagcaggcgcgccgcacggtcgcgcgcccgcattcgggcgggtacggt
cggaccacccgcgcgttcctgggcaatcggagctcggagccgggcagccccgccggtggt
gcgcaaccgtcgacgccgccggccggccatccggcgctcaagctctatcgctctgtcgag
agtggatcgtcagagcgcacgaacaacgacgatgaagccgaggacgcgatcaaggaccgc
aagtcggtctactcgatgcaactgcccacgtcctcgtcgggcggcggttccgaggtgagc
caggccatcaacgcctctctcgcacgcaagtggggagcagcccgacgttcggggccggtc
cacacgagcttccaggacctgatgcgcctgcggtcatcgtcggtcatcggcaacgacttc
accggctcgggctcgctgcccgtgaccaccggctcgcacaccatgaccaacaaaaacgac
gagtatgtgatcaagttcgtgcacgacgacgagttgttcaggatcgtgtgcagctgcgag
atgaacgccagccagatcaaggcggcgatgatccaacacgtcaaggccttcctgggcatc
cccgacagcgatcccaagggcaaggacaaggaggactcggagagcgaaagcgaatcgaaa
tcgcggccgtcgtcgtcgtcgattctgtcttcgtcgtcatcgtcgtcgtcctccctgtcg
tcctcctcctcctcctcctcgtcgccgcgcacctccacctcgtcgccgcctccgctcggc
caatcgttggacgagaaggactacgtgctcaagattcctggcgtcaactactacttggtc
aaggaggagcagtcgctgcatctggtgggcgtgctgcaggtctgcaagaagagcttcgtg
tccttcccgctcgagatgatccctcggccttcgaccgacgtcctgcacgagaacgacaag
ctcaacgtgcgagagaagatcatgtcggagctcaacgccaacacggaggtgtttgagctg
ctcagcaaccccatctcgggcgacaacccgctgctccagatcctcaaatcggacaacgac
gaaatcaactccttccgcaaacgcatcaccaaggttcgccgcgcggtgttgaaggagcgg
gaggcgctcgtgcgccagctctccgaagcccactccaacagcaaatacgacacctcgttc
ttgccccagtacagggagtcggagccgctgccgctgaacctgcccaactcgttcatcatc
ctcgcctaccagccggccgacgagaaggacgaggtccagacctcgacccagaagttcagc
gtcacccgcaaccaaaccgtcgccgaactcaagagcaacatgttccgcaagtacaagggc
acgcacccgctggccacgggcacggaggaagactacatcgtgaaggtgactggctttaag
gagtacatgatcggctcccacaagatcctctcctacgactacatcaggaaatgcttgagc
aagaaggtgaccccgatcctgtcgctcgttcccctcaaggacgtggacctgatgatcccc
gagcccgttgaagactctgttgtcgacatgatcttgtcgcgggagaagaacgtgcacatg
tcgaagctgcgatataaggaccaggagccgcgcaagcccatctcggagatggtgcagcag
ctgcgggtgaagatcaacggcgtcgataatgtcgacacgttcaaccacatcatcaagagc
tggatgcgggagcagaagggcaagaaggagcacaaggagcagaagggctcgctgatcgac
gacaaggacggcggcaagaagaagacctactgcctctacgtctgcgcgcagatctaccac
ggcgatgaactgattgcggatgacatgtacacgaacgcgatcctgtatagtaatggacct
ctgtggaacgagtggctcgtttcctctgtcaaactacgagacatcccgcgagggtcacgg
atgtgcttcacgctctaccggcgacagctggacaacacggtgtcggccgaggctgtgttc
acggagaagggccggttcaacgagaagaccgacgtgccgctcgggtgggtcaacttccag
ttcatcgaccacaaggaccagctgcggcagggcctctgctcgttcaagctgtggctcggc
aagcccaacccgatcggcacctgcgtggagaacgtggcggtcaaggacaaggagcgggcc
accacgctccacgtcgagttccagatccaccgcacggcggtctacttcccgccgccgccg
acggtcaaccccgccgacgcggccgccgccgcccgcggctcgagccagcccgcgcccgcg
ccctcgtcggccgacgcctccaagcagaagatcatcaagctccagctcgaagagatcatg
aagaaaggttacgaactgcgactctgctcttcagccactgccgcactcgtcggccatccg
ctgacagcgctcggggaggacgagcggcagcttttgtgggagtgccgagagttctgcgcc
cagttcccctcgctccttcctcgtttcctccagtacgtcaagtggaacgacagggaaagt
gtgctcgaggcctatcgcatgctggcgctgtggagcccgcctacgcccttcgaagcgctt
tcgctgctcgacgccaagtacgcctcgccggtggtgcgcgcctacgccgtcaagcgactg
cacgagctcgacgatcgggcgctctccgacttcctcctccagctcacccaggtgttgaag
tacgaggcgtaccactactcgcccctggccgagtttttgctctcgcgcgcgctcatgaac
gtcaaccagatcgggcatgccttcttctggcttctcaagtcggagctgcataaccccacg
atcgcgtcgcgttattcgctgttggccgaggcctacctgcgcggctgcggagcccacagg
caggagctcgtcaagcagaacaaggtcctcaaccagctggccaaggtcgccatgcgcgtc
aaggaggctccctcgtcctccgaaaagaagaaggtgctcgaggatggcctgaggagaatg
gagttcccggccaggttccagctgccgctggacccgcgacaggaggtgaagggggtgatc
gtcgacaagtgtaaatatatggacagcaagaagcagcccctctggctcgtttttgaaaac
gccgagaagcgaggcgcgcccatccgcgtcatcttcaaggccggcgacgatcttcggcaa
gacgtgttgacgctgcaaatgctccgcatcatggacaagctgtggaaggaggaggggctc
gacctccgcctcaatccctacggctgcgtcgccacgggcgatgagctcggcatgatcgag
gtggtgctcaacgcctcgactacggcatcggtcaacaaggagaagggcgggtcgaaggcc
gtactgtacaaggacaccctcaccagctggctcaaggagaagaacccttcggcggaggcg
ttcgaggccgcgcaggagaacttcatgctcagctgcgccggctactgcgtggcgacgtac
gtgctgggcatcggcgatcgacacaacgataacatcatgatcacccaatttggtcatttg
ttccacatcgatttcgggcacttcctgggcaacgtgaagagcaagctgggaatcaagcga
gagcgggcgccgttcattttcaacccccagttcgcgcacgtgctgggcggctcacagggc
acgcgctacgcccagtacgtcgagacctgccagcgggcctacaacatcgtccgcaagcac
gcccacatgttcatcaacctcttcatgatgatgttatcaacgggaattccggagctgcag
tgcgaggaggacatcctgtacctgtgcgggtcgctgctggtgggcaccgaggagaaggcc
gcggccgagaactttgccaagctcatcgaggaggcgaggaagaccaagtcggtgctcgtc
aacgacatcgtccacatctgggctcactccaagaagtga

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