Acanthamoeba castellanii: ACA1_199620
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Entry
ACA1_199620 CDS
T02667
Name
(RefSeq) phosphoinositide 3-kinase family, accessory domain (pik domain) domain containing protein
KO
K00922
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:
2.7.1.153
]
Organism
acan
Acanthamoeba castellanii
Pathway
acan00562
Inositol phosphate metabolism
acan01100
Metabolic pathways
acan04070
Phosphatidylinositol signaling system
acan04081
Hormone signaling
acan04620
Toll-like receptor signaling pathway
acan05100
Bacterial invasion of epithelial cells
Brite
KEGG Orthology (KO) [BR:
acan00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00562 Inositol phosphate metabolism
ACA1_199620
09130 Environmental Information Processing
09132 Signal transduction
04070 Phosphatidylinositol signaling system
ACA1_199620
09133 Signaling molecules and interaction
04081 Hormone signaling
ACA1_199620
09150 Organismal Systems
09151 Immune system
04620 Toll-like receptor signaling pathway
ACA1_199620
09160 Human Diseases
09171 Infectious disease: bacterial
05100 Bacterial invasion of epithelial cells
ACA1_199620
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
acan04131
]
ACA1_199620
Enzymes [BR:
acan01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.1 Phosphotransferases with an alcohol group as acceptor
2.7.1.153 phosphatidylinositol-4,5-bisphosphate 3-kinase
ACA1_199620
Membrane trafficking [BR:
acan04131
]
Endocytosis
Rab GTPases and associated proteins
Rab associated proteins
ACA1_199620
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PI3_PI4_kinase
PI3Ka
PI3K_C2
DUF4135
Motif
Other DBs
NCBI-GeneID:
14920505
NCBI-ProteinID:
XP_004341771
UniProt:
L8H2G4
LinkDB
All DBs
Position
Unknown
AA seq
1188 aa
AA seq
DB search
MHIRVVQSLASSRSAEEVTALYRSNSSDSAPRNAQQLPLSYSSPSLSVSACISPRARPPP
PVPPRSGATGAAAQPPMPGRLGWSGGGGGGSTLHHLSPPPDAGQRVQQRQRSRTFSSGLD
APTADDARGAPGTPLPSLSLSTSTSSVSSTSSTLAQSSPTLRAPVKMGGSGLVASFRSRA
NTVSPPPPPPLSPEPNKFHFMGLLRPSPPAPAAAAAATITTTTTSIIAPPVSPTAAPTSA
PAAVGGRSDDGYDVVDPTGEASAGPPVLITHLVGVNQQSKPTPYIWEKHKPVRKRRTVVN
ARATQRITTRMAPNEEVEHFRACMERLSPTYQQNWLPFGQILASTTDVPFYFSGVTFAVF
FRFPDATDDQTTTTATTTTTNLPFLFCKGRETLEWAVQEILRKTGRESERADDKIIQFSG
LAAVYAFDLSVRLKDFAHVRNALKRRDKIVLLVWDRRRDKPQLCASEFLARHKPESSLGW
EDDASLGLRYQDKEVYPLEKLDDHCVEVKLLCVENFRPETVAELAGGGYAAKCESFAFYV
RLELRHGERTICPPVISKRTAAPPVWCEWLRLSLPLSDLPLESRCVLTLFAVNLLRDEQL
VYGTASCNLFDRDGWFMSGVCKLPLNASADAPASQLNERVAGLPTSDRSPRITRLVRAAL
VMEMERAPYPIAFPQVPHFTPLIGRERANFKVASSVSPDPGELAALHAILKKNTLDELSE
EERTLVWKYHSHCFAFPQALPKLLLSVPWEDPSAVKQAHRILETWDRLSPFTALQLLDQY
YPDTVVREYAVQCLCDMTDPDLVNHLLQLIQALKFERNHDSALARFLLYRALHNRTLVYM
ESCGEHADELFAQLEIVAKLRQLNEAARTYKKAERTKVLQDGLTAYTQFASFPAQFHLPI
NPQIVATGFVVDKCRVMDSSTAPLWLCFENQDRNGSPDLLILQVFTEMDRLWKREGYDLH
MSIYGVVSTAFNEGFIEVVSNASTCSKIQKDAAGLAGALQRTPLFNWLQKHNTTEQDISS
AVQNFVHSCAAYSVASYVLGIGDRHNDNVMITREGHLFHIDFAHILGDFMKFGAYKREKA
PFVFTDEFVHVMGGAVSDNYQLFVDLGAIAFNILRNNADILISLFVMMLSAGIPLLRTRK
DIKFLESALALHLTEEEAAATFKGLAAEALACKTTRVLFFMHNLAHPD
NT seq
3567 nt
NT seq
+upstream
nt +downstream
nt
atgcacattcgtgtcgtgcagtcgttggcgtcgtcgagatcggcggaggaagtcacagcc
ctgtaccgcagcaactcctcagacagcgcgccgcgaaatgcgcagcagctgcccctgtcc
tactcgtccccgtcgctctccgtgtcggcctgcatctctcctcgcgcccggccgcccccg
cctgtgcctccgcgatcgggcgccaccggtgcagctgcccagccgcctatgccgggccga
ctcggttggagcggcggtggcggtggcggcagcacgttgcaccacctctcaccaccacct
gacgctgggcagcgggtgcagcagcggcagcgctcccgcacgttcagttcggggctcgac
gcgccgacggccgatgatgcccgaggagcgcccggcacaccactaccctctctatctttg
tcgacgtcgacatcatcggtatcttcgacgtcgtctacgctcgcgcagtcgtcgccgacg
ttgcgcgcgccggtgaagatgggcggctcggggctcgtcgcctcgttccgctcacgcgcc
aacaccgtgtcgccgccgccgccgccgccgctctcgcccgaacccaacaagttccacttc
atgggcctgctgcgaccctccccgccggctcccgcagcagcagcagcagcgacgataacg
acgacgacaacctcgataattgctccgcccgtcagccccacagcggctcccacgagcgcc
cctgcggcggttggtggccgcagcgacgacggctacgacgtcgtagatccaaccggggag
gcgtcggcgggtccaccggtgctcatcacgcacctggtgggcgtgaaccagcagtcgaag
cccaccccctacatctgggagaagcacaagcccgtgcggaagcggcgcaccgtggtcaac
gcccgcgccacccagcggatcaccacccgaatggcaccgaatgaggaggtagagcacttc
cgcgcctgcatggaacggctgagtccgacgtaccagcagaactggctgcccttcgggcag
atcctggccagcacgacggacgtgccgttctacttcagcggggtcacctttgccgtgttc
ttccgcttccccgacgccactgacgaccagaccaccaccaccgccaccaccaccaccacg
aacctgccgttcctcttctgcaagggacgcgagacgctcgagtgggccgtccaggagatc
ctgcgcaagaccggccgcgagagcgaaagggctgatgacaagatcatacaattcagcggc
ctggcggcggtctacgcgttcgacctctcggtgcggctcaaggacttcgcccacgtgcgg
aacgcgctcaagcgacgcgacaagatcgtgctgctcgtgtgggaccgtcgccgcgacaag
ccccagctgtgcgcctccgagttcctggcccggcacaagccggagagcagcctcgggtgg
gaagacgacgcgagcctcggcctgcggtaccaggacaaggaggtgtatccactggagaag
ctggacgaccactgcgtcgaggtcaagctgctgtgcgtggaaaacttccggccggagacg
gtggccgagctcgcgggtggcggatacgccgccaagtgcgagagcttcgccttctacgtg
cgcctggagctgcgccacggcgagcggaccatctgcccgcccgtcatcagcaagcgcacg
gccgccccgcccgtctggtgcgagtggctccgcctgagcctgcccctcagcgacctgccc
ctcgagtcccggtgtgtgctcaccctctttgccgtcaacctgctgcgcgacgagcagctc
gtctacggcacggcctcgtgcaacctgttcgatcgcgacgggtggtttatgagcggcgtg
tgcaagctgccactcaatgcgtccgccgacgcgcctgccagtcagctcaatgagcgagtc
gctgggctgcccacctctgaccgatctccgcggatcacccgcctcgttcgtgcagcgctg
gtgatggagatggagagagctccataccccatcgccttcccgcaagtgccgcacttcacg
cctctgatagggcgggagcgggccaactttaaggttgcgagctcagtgagccccgacccc
ggtgaactcgccgccctccacgccattctgaagaagaacacgctggacgagctgtcggag
gaggagcgcacgctggtgtggaagtaccactcgcactgcttcgccttcccgcaggccctc
cccaagctcctcctgtcggtgccctgggaggacccctccgccgtcaaacaggcacaccgc
atcttggagacctgggaccgcttgagccccttcaccgcgttgcagctgttggaccagtac
tacccggacacggtggtgcgcgagtacgccgtgcagtgcctgtgcgatatgaccgatccg
gacctggtcaaccacctgctccagctcatccaggccctcaaattcgagcgcaaccacgat
tcggcgttggcccggtttctgctgtaccgggcgctgcacaaccggaccttggtgtacatg
gagtcgtgtggggagcacgccgacgagctcttcgcgcagctcgagatcgtggccaagctg
cggcagctcaacgaggctgctcgcacctacaagaaggccgaacggaccaaggtgctgcag
gatgggctgacggcgtacacgcagtttgcgtccttcccggcgcagttccacctgcccatc
aacccgcagatcgtggccacgggcttcgtcgtcgacaagtgccgcgtcatggacagcagc
accgcaccgctgtggctgtgcttcgagaaccaggacaggaacgggagccccgacctcctc
atcctccaggtcttcaccgagatggaccggttgtggaagcgggaggggtacgacctgcac
atgtccatctacggcgtcgtgtccaccgctttcaacgagggcttcatcgaggtggtctcc
aacgcctccacctgctccaagatacagaaggacgcggcaggcctggccggagcgttgcag
cggaccccgctcttcaattggctccagaagcacaacaccacggagcaagacatcagttcg
gcggtgcagaactttgtgcacagctgcgcggcctactcagtggcgtcgtacgtgctgggc
atcggggaccgacacaacgacaacgtcatgatcacccgcgaaggacacctcttccacatc
gactttgcgcacatattgggtgatttcatgaagttcggagcctacaagcgggagaaggcg
ccctttgtcttcacggacgagttcgtccacgtgatgggcggagcggtctccgacaactac
cagctcttcgtggacctgggcgccatcgcgttcaacatactccgcaacaacgccgacata
ctcatctcgctgttcgtcatgatgctctcggccggcattcccttgttgcggacacggaag
gacatcaagtttttggagagcgcgctcgccctccacctcaccgaggaggaagccgccgcc
acgttcaagggtctcgctgctgaagcgctcgcctgcaaaaccacgcgcgtgctgttcttc
atgcacaacctcgcccaccccgattga
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