KEGG   Acanthamoeba castellanii: ACA1_270360
Entry
ACA1_270360       CDS       T02667                                 
Name
(RefSeq) phosphoribosylamine-glycine ligase
  KO
K11787  phosphoribosylamine--glycine ligase / phosphoribosylglycinamide formyltransferase / phosphoribosylformylglycinamidine cyclo-ligase [EC:6.3.4.13 2.1.2.2 6.3.3.1]
Organism
acan  Acanthamoeba castellanii
Pathway
acan00230  Purine metabolism
acan00670  One carbon pool by folate
acan01100  Metabolic pathways
acan01110  Biosynthesis of secondary metabolites
Brite
KEGG Orthology (KO) [BR:acan00001]
 09100 Metabolism
  09104 Nucleotide metabolism
   00230 Purine metabolism
    ACA1_270360
  09108 Metabolism of cofactors and vitamins
   00670 One carbon pool by folate
    ACA1_270360
Enzymes [BR:acan01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.2  Hydroxymethyl-, formyl- and related transferases
    2.1.2.2  phosphoribosylglycinamide formyltransferase 1
     ACA1_270360
 6. Ligases
  6.3  Forming carbon-nitrogen bonds
   6.3.3  Cyclo-ligases
    6.3.3.1  phosphoribosylformylglycinamidine cyclo-ligase
     ACA1_270360
   6.3.4  Other carbon-nitrogen ligases
    6.3.4.13  phosphoribosylamine---glycine ligase
     ACA1_270360
SSDB
Motif
Pfam: GARS_A Formyl_trans_N GARS_N AIRS_C GARS_C AIRS ATP-grasp ATP-grasp_2 RimK CPSase_L_D2 ATP-grasp_3 DSRM_REH2 Usp U3_snoRNA_assoc
Other DBs
NCBI-GeneID: 14920349
NCBI-ProteinID: XP_004341647
UniProt: L8H537
LinkDB
Position
Unknown
AA seq 1031 aa
MEGELKQHTVVVVGSGGREHAIVWKLSQSPKVAHIYVLPGNGGTEALGRELAKKGAPAVV
QNVAGISTNEAIVAFAQEKKASLVVVGPEAPLAAGLGDDLNKAGVPCFGPSKAGAQIEAS
KVFAKDFMHKHNIPTATYQVFDDAEKALKYIDDTPHTLVVKASGLAAGKGVIVPKNKDEA
KQAVREIMVDKVFGEAGNLVVLEELLVGPEVSFLGFCDGTTVVPMPAAQDHKRALDNDKG
ANTGGMGAFAPTPAVTPEMAQEWTATVLQAALDGLKKDGIPFVGVLFAGLMLTKNGPRVL
EYNCRFGDPETQVILPLLKTDLFEVMLACVQGRLAQLRVEWATARAAVTVVAASGGYPDK
YPVDKPIAGLNSLPQSIDAEGGVYVFHAGTKAAADGQGVVTSGGRVLAVTAVSPRPAQAI
ARAYAALDKIHFDGMHYRCDIGSYFANNTLRLAVLGSTRGTDMQAIIDAIARRELNAEIA
LVVSNRADAYILERARAHGIAHHFVEPRDADGKLKPREAYDREVIAALDGVDGGVDLVLM
IGYMRIVSAAFVERFRGRLYNVHPSLLPDFAGGMDLDVHQAVLDSGAKFTGCTVHVVTEE
VDAGPILVQKRCAIDATDNADTLKAKVQHLEGVALIEAIQLFEQQEKQKYRAEEVKRQQR
REKRKAAEGQGPVTYRSAGVDIDAGNLLVERIKPFTKATARPGTSANIGGFGGLFDLKEA
GYRDPLLVSGTDGVGTKLKIAQEVKKHDTLGQDLVAMCVNDILTRGAEPLFFLDYFATGA
LAVDEATQVVKGIADGCMLAGCALVGGETAEMPGMYPPGEYDLAGFAVGAVERDGVLPIM
DTIKEGDVVIGLASSGLHSNGFSLVRHIIKLNNIDVSAKPPFASKHEKLAHALLEPTRIY
VKSVLPLMKARKIKAAAHITGGGLLENIPRVLTPKIGVDLDVAQWSVPPVFGWLASLGQL
QPREMLRTLNVGIGMTLLVAPDHVASVLEALTASGEDARVIGKVVPRRLDDSEQVHVANA
QLLASPAPATF
NT seq 3096 nt   +upstreamnt  +downstreamnt
atggaaggagaactgaagcagcacacagtggtggtcgtgggcagcggtggccgcgagcac
gccatcgtttggaagctcagccagagccccaaggtggctcacatctacgtcctgcccggc
aatggcggtacggaagcgctgggccgggagctggccaagaagggtgcgccggcggtggta
cagaacgtggccgggatcagcaccaacgaggccatcgtcgcctttgcccaggagaagaag
gcctcgctcgttgtggtcggaccggaggctcctctcgccgctggacttggtgacgatttg
aacaaggccggcgtgccgtgcttcggtccctccaaggcaggcgctcagatcgaggcctct
aaagtcttcgccaaggatttcatgcataaacacaacatccccaccgccacctaccaggtg
tttgacgatgccgagaaggcgctcaagtacatcgacgacaccccacacacgctggtggtc
aaggcgtcaggcctggcggccggcaagggcgtcatcgtgcccaagaacaaggacgaggcc
aagcaggctgtgcgcgagatcatggtcgacaaggtgtttggcgaggccggcaatctggtg
gtgctggaggagctgctcgtcggacccgaggtctctttcctcggcttttgcgatggtacc
acggtggtccccatgcccgccgctcaggaccacaagagagcgctcgacaatgacaagggc
gccaacacgggcggcatgggtgccttcgcgcccacgccggccgtcacgcccgagatggcg
caggagtggaccgccaccgtgctccaggccgccctcgacggcctcaagaaggacggcatt
cccttcgtcggcgtcctctttgccggtttgatgctgaccaagaatgggccgcgggtgctg
gagtacaactgtcggttcggcgaccctgagacgcaggtcatcctgcccctcctgaagacg
gacctgttcgaggtcatgctggcctgcgtgcagggccggctggcccagctccgcgtcgag
tgggccaccgcgcgcgcggccgtcaccgtcgtcgccgcctcgggcggctatcccgacaag
taccccgtcgacaagcccatcgccggtctcaactctctgccccagtccatcgatgccgag
ggtggcgtgtatgtgttccacgcgggcacgaaggcggccgcggacggccagggggtggtg
accagcggcggccgcgtactggcggtgacggccgtgagcccccggccggcccaggccatc
gcccgggcctacgccgcgctcgacaagatccacttcgacggcatgcactaccgctgcgac
atcggatcctactttgccaacaacacacttcgtctggcggtgctggggtcgacgcggggc
acggacatgcaggccatcatcgacgccatcgcgcgccgcgagctcaatgccgagatcgcg
ctcgtggtgagcaaccgcgccgacgcctacatcctcgagcgcgcccgcgcgcacggcatc
gcccaccactttgtcgaaccgcgcgacgccgatggtaagctcaagccgcgcgaggcctac
gatcgcgaggtgatcgccgcccttgacggcgtcgacggtggcgtcgatctggtgctgatg
atcggctacatgcgcatcgtgtcggcggcctttgtcgagcggttccgcgggcgcctgtac
aacgtgcacccgtcccttctgcccgactttgccggcggcatggacctcgacgtccaccag
gccgtgctcgacagcggcgccaaattcaccgggtgtacggtgcatgtggtgacggaggag
gtggacgcgggtcccatcctggtgcagaagcggtgcgccatcgacgcgaccgacaacgcc
gacacgctcaaggccaaggtccagcacctcgagggcgtggcgttgatcgaagccattcag
ctgttcgagcagcaggagaagcagaagtaccgggccgaagaggtcaagcgccagcagagg
cgcgagaagcgcaaggccgccgagggacaaggacccgtgacgtaccgcagtgcgggcgtg
gacatcgatgcaggcaacctgctcgtggagcgcatcaagcccttcaccaaggccaccgcc
cgtcccggcacctcggccaacattggcggatttggcggtctgttcgatttgaaggaggcc
ggctacagggatcccctgctcgtgagcggcactgacggtgtgggcaccaagctcaagatt
gcgcaggaagtgaagaagcacgacaccctcggccaggatctggtggccatgtgcgtcaac
gacatcctcacgcgaggcgccgagccgctcttcttcctggactacttcgccaccggcgct
ttggccgtcgacgaggccacccaagttgtcaagggaattgcggatggctgcatgctggcg
ggatgcgcgctggtgggcggcgagacggcagagatgcccggcatgtacccgcccggcgag
tacgacttggccggctttgccgtgggcgcggtcgagcgcgacggcgtgctgcccatcatg
gacaccatcaaggagggtgacgtggtgatcggattggcgtcctcgggtcttcactccaac
ggcttctcgctggtgcggcacatcatcaagctcaacaacatcgacgtctcggccaagccg
ccgttcgcttcgaaacatgagaagttggcccatgcgctgctcgagcccacgcgaatctac
gtcaagtcggtgctgcccctcatgaaggcccgcaagatcaaggccgccgcccatatcaca
ggtggtgggctgctggagaacatcccgcgagtgctgacgcccaagatcggggtcgatctg
gacgtggcgcagtggagcgtgccgccggtgttcggctggctcgcgtcgctggggcagctc
cagccgcgcgagatgctgcgaaccctcaacgtgggcatcggcatgaccctcctcgtcgca
cccgaccacgtcgcctccgtcctggaagccctcaccgcctctggggaagacgcgcgcgtg
atcggcaaggtcgtgccgcgcagactggacgacagcgagcaggtgcacgtggccaacgcc
caactgctggcctcccccgcccccgccaccttctga

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