Acanthamoeba castellanii: ACA1_360410
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Entry
ACA1_360410 CDS
T02667
Name
(RefSeq) phosphoinositide 3kinase family, accessory domain (pik domain) domain containing protein
KO
K00922
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:
2.7.1.153
]
Organism
acan
Acanthamoeba castellanii
Pathway
acan00562
Inositol phosphate metabolism
acan01100
Metabolic pathways
acan04070
Phosphatidylinositol signaling system
acan04081
Hormone signaling
acan04620
Toll-like receptor signaling pathway
acan05100
Bacterial invasion of epithelial cells
Brite
KEGG Orthology (KO) [BR:
acan00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00562 Inositol phosphate metabolism
ACA1_360410
09130 Environmental Information Processing
09132 Signal transduction
04070 Phosphatidylinositol signaling system
ACA1_360410
09133 Signaling molecules and interaction
04081 Hormone signaling
ACA1_360410
09150 Organismal Systems
09151 Immune system
04620 Toll-like receptor signaling pathway
ACA1_360410
09160 Human Diseases
09171 Infectious disease: bacterial
05100 Bacterial invasion of epithelial cells
ACA1_360410
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
acan04131
]
ACA1_360410
Enzymes [BR:
acan01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.1 Phosphotransferases with an alcohol group as acceptor
2.7.1.153 phosphatidylinositol-4,5-bisphosphate 3-kinase
ACA1_360410
Membrane trafficking [BR:
acan04131
]
Endocytosis
Rab GTPases and associated proteins
Rab associated proteins
ACA1_360410
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PI3_PI4_kinase
PI3Ka
PI3K_C2
PI3K_rbd
HEAT_2
DUF4135
Peptidase_C14
Motif
Other DBs
NCBI-GeneID:
14923995
NCBI-ProteinID:
XP_004352502
UniProt:
L8HCV8
LinkDB
All DBs
Position
Unknown
AA seq
1368 aa
AA seq
DB search
MSLSVDPMVPAAMRPGEDVFTANLASAITAKSQLKSSGSPSKDPLSSSGGADAVRRPSNA
LPSRFGISLVVPSGSQVDLKCGVGDTAADFIRSNFNKMKFMLGATANAAHYVLQTPDGET
LASDALVASSAYVEQCVLGKSQPSLFLKPRERGPAPLPPMRPYAMTTSSAPASPSSLSTS
PRRLPFSYIPTATPPPSVAALSMASPSSSLELSPPSSPSSSLSSTPRTSNAHSPFSLSPA
TSFVAHTQSGDEIPTSPLATTSGRATSSDLSSSPPVIDIDVHEDEPFDLQVLLAGAVTTI
VECKPTDTAGNVLTRLDIPDSRLHCYSLATPASNALDGALVLSKLEYIRECRRHYILPQL
RVVEDTPSLSKEEKKENKDIGGLIGQKLCWTNVEDEISAFRKTMARVRKEVVLAEELRGL
DDGELNIRLSGAPNPTVDRLLIRVVLPLEKKSTNLLVTNDRGMETADSFLQRLLQLPLFS
TSGFYHAQTHPHLLLRAKGRLEHIVGKYPLLAFGMECVESKRWPKLVLLKRSEDYIALAK
PKQDDASASSSSTTTAGWTSARVPRTPRVRATPFSPRLGGASEGTRDVGESETGPTAIQE
VKAGEATEWEENCEGDQVDDEEEALAPRYDHALMAGELVRWDQKSHISLWELENRPFRIK
VMGVERTNELGCPSWRKFSPDLAPDDVIGSLYVHVGVYYGGQLLVKDAVTKPVPCSANPR
WGQWLTFDDLLFSNESRVCCTLYAKTARDTDAIPLAWANFNIFDYKHELRSGLHTLSMWP
DGPANPIGTCVGNAGFAHATQLALELDSFPLPVVFPTDGTTGKTKGPNRNSCLVLGGGEE
ELELVEEVEKILAMDSLHRLTPTQKKIVNTLRGYCLARPNALPKFLQAVNYADHISVQEM
HSLLGFFRQPTAVEALELLDSKFPDAKVRDHAVECLEALSHDELLDYLLQLVQVIKYEAY
HDSGNAFYWYLRSEVHAPEISERYSLILEAYLRGSPSHRRRLHRQNQALNAIYHVGTKIK
GLNSIQHSSRLSQDEAIKTEEERAEVLSAALAVIKLPSTFGLPLRADMEVADLLTDKCKF
MDSKKRPLWLVFENAQPARPPIYTIFKCGDDLRQDMLTLQMLRIMDKMWKNEGYDLCVTP
YGCIATGADMGFIENSATTAAVAKESGYGARGAFKEDPLKNWLLKHNPTKEQWDAALRNF
IRSCAAYCVATYVLGIGDRHNDNVMVTKDGRLFHIDFGHFLGNFKKKFGFKRERAPFVLT
PDHAFVMGGRGSEGFTLFITTACRAYNILRKHAMGTSLLNLTVFLLEQTGIPELKSAEDL
EYLRYAFATDLDDNAAAARFTELIHAALDCWTTRFNNAIHLIAHGGKG
NT seq
4107 nt
NT seq
+upstream
nt +downstream
nt
atgtcgctgtcggtcgaccccatggtgccggcggcgatgcggccgggcgaagacgtgttc
acggccaacctggcgtcggcgatcacggccaagagccagctcaagtcctccgggtcccct
tccaaagacccgctctcgtcctccggaggcgccgatgccgtgcgccggccttccaacgct
ctcccctcgcgctttggcatctccctcgtcgtcccgtcaggctcgcaggtggatctgaaa
tgtggtgtgggcgacacagcagccgacttcatccgctccaactttaacaagatgaagttt
atgctgggcgcgacagcgaatgcagcccactatgtgctgcaaacgcccgacggagagaca
ctcgcctcggatgcgctggtcgcgagcagtgcctacgtggagcagtgcgtgctgggcaaa
tcgcagccctcactcttcctcaagccccgagagcgcggccctgctccgctgccgcccatg
cggccgtatgccatgaccacctcgtcggcgcccgcctctccctcttccctctccacctcc
ccgcggcgactgcccttcagctacatacccaccgcgacaccgccgccgagcgtggcggcc
ctatccatggccagtccgtcgtcgtcgctcgaattgtcgccgccctcatcgccctcgtca
tcgctgtcctcgacaccgcgcacgtccaacgcccactcgcccttttccctctcgccggcc
acctccttcgtggcgcacactcagtcgggcgatgagatcccgacctcgcccctcgccacc
acgtccgggcgtgctacgtcatccgatctctcttcgtcgccgccggtcatcgacatcgat
gtccacgaggacgagccgtttgacctgcaggtgctgctggcgggggcggtgacaacgatc
gtggaatgcaagccgaccgacactgcaggcaacgtgctcacgcgtctggacattcccgac
tcccgcctgcattgctacagtctggccactcctgcctcaaacgccctcgatggcgctctc
gtgctgtccaagctcgagtacattcgcgagtgcagaaggcactacatcctcccccagcta
cgggtggtcgaggacacaccgagcctgagcaaagaggaaaagaaagaaaacaaagacatt
ggcggattgatcgggcagaagctgtgttggaccaatgtagaggatgagatttcagcgttc
cgcaagaccatggccagagtgaggaaagaagtggtgctggccgaagaactgcgaggattg
gacgacggggagctcaacatccgattgtccggcgcgcccaatcccactgtcgatcgcctg
ctcatccgggtcgtgctgccgctcgagaagaagagcaccaacctgctcgtcaccaacgat
aggggaatggagactgcggattccttcctgcagcgactgcttcagctgcccctgttctcg
acctccggcttctaccacgcccagacgcacccgcacctcctgctacgagccaagggcagg
ctggaacacatcgtgggcaagtacccgttgctggcctttggtatggaatgcgtggaaagt
aagcgttggccgaagctggtgctgctcaagcgatcggaggactacatcgcgctggccaaa
cccaaacaagacgacgcttccgcatcatcgtcgtcaaccaccactgccgggtggacctcc
gcccgcgtcccgcgcaccccacgagtgcgtgcgacaccattttcgccgcgcttgggagga
gccagcgaggggacgagagacgtcggcgagtcggagacagggccgacagcgatacaagag
gtgaaggcgggcgaagcgacggagtgggaggagaattgcgagggagaccaggtcgacgat
gaagaggaggccctcgcgccgcgctatgaccacgctctcatggccggcgagctggtgagg
tgggaccaaaagtcgcacatctccctgtgggagctggagaaccggccatttcgaatcaaa
gtgatgggcgtggagaggaccaacgaattgggctgtccctcgtggaggaagttctccccc
gatctcgctccggacgacgtcatcggctctctttacgtccacgtcggggtgtactacgga
ggacagctgctggtgaaggacgcggtcacaaagcccgtgccgtgttctgccaacccgcgc
tgggggcagtggctcacgttcgacgatctactcttctcgaatgaatcgcgcgtttgctgc
accctctatgcgaaaacggccagagacacggacgcaattccgcttgcttgggccaacttc
aacatcttcgactacaagcacgaactacggtccggcttgcacaccctctccatgtggccg
gacggaccggccaacccgatcggcacatgcgtgggtaatgcgggctttgcgcacgccacg
cagctcgcactcgagctcgactcctttcccctccccgtcgtctttcccaccgatggcacg
acgggcaagacgaagggacccaaccgcaattcttgcctggtgctgggcggcggagaggaa
gaactggagctggtggaagaggtggagaagatactcgccatggactctcttcaccggctg
accccgacccaaaagaagatcgtcaacacgctgcgcggctactgtctggcgcggcccaac
gccttgccgaagtttttgcaggccgtcaactatgccgaccacatatctgtccaggagatg
cactcgttgctgggcttcttcagacagccaacggcagtcgaggccctggagcttctcgac
tccaagttccccgatgctaaggtgcgagatcatgcggtcgaatgtctggaggccttgtcc
cacgatgagctgctcgactacctcctccagttggtgcaggtcatcaagtatgaagcctat
catgactctggcaatgcgttctattggtacctgcgatcggaggtgcacgcgccggagatc
tcggagcggtacagcctcatcctcgaggcctacctccgcggctcgccgtcccaccgtcgt
cggctgcatcgacagaaccaagccctcaacgccatctaccacgtcggaactaaaatcaag
ggcttgaactccattcaacattcatctcgtctgtcccaggacgaagcgatcaagacggaa
gaggagcgggccgaggtgctgagcgccgcactggcggtgatcaagctgccctccaccttt
gggctgccgctgcgggcggacatggaggtggcagatctcctcacagacaagtgcaagttc
atggactccaagaagcggccgctgtggctcgtctttgagaacgcccaacccgcgcgaccg
cccatctacaccattttcaagtgtggcgacgatctccgtcaggacatgttgacgctgcag
atgcttcgaatcatggacaagatgtggaaaaacgagggctacgatctgtgtgtgacgccc
tatggctgcattgccaccggggcggacatgggtttcattgagaactcggcaaccacggct
gcagtcgccaaggagtcgggctacggggccagaggcgccttcaaggaggacccgctcaag
aactggctgctcaagcacaaccccaccaaagaacagtgggacgcggcgctgagaaacttc
atccgatcttgtgcggcgtactgcgtggccacctatgtgctggggattggcgatcgacac
aacgacaacgtgatggtgaccaaggacggccgactgttccacatcgacttcggccatttc
ctggggaacttcaaaaagaaattcggcttcaagcgggaacgcgctccgttcgtgctgacc
ccggaccacgccttcgtgatgggcggtcgcggcagcgaaggattcacactcttcattaca
actgcttgccgcgcctacaacatccttcgcaagcacgccatgggaacgagcctgctaaac
ttgaccgtattcctcctcgagcagacgggcattccagagctgaagagcgcagaggacctg
gagtacctgcgctacgccttcgcaaccgatcttgacgacaatgcagccgcagcccgcttt
accgagctcatacacgccgccctcgactgctggaccacacgcttcaacaacgccatccac
ctcatcgcgcacggcggcaagggctga
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