Antrostomus carolinensis (chuck-will's-widow): 104527062
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Entry
104527062 CDS
T08541
Symbol
GCLC
Name
(RefSeq) glutamate--cysteine ligase catalytic subunit
KO
K11204
glutamate--cysteine ligase catalytic subunit [EC:
6.3.2.2
]
Organism
acar
Antrostomus carolinensis (chuck-will's-widow)
Pathway
acar00270
Cysteine and methionine metabolism
acar00480
Glutathione metabolism
acar01100
Metabolic pathways
acar01240
Biosynthesis of cofactors
acar04216
Ferroptosis
Module
acar_M00118
Glutathione biosynthesis, glutamate => glutathione
Brite
KEGG Orthology (KO) [BR:
acar00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
104527062 (GCLC)
09106 Metabolism of other amino acids
00480 Glutathione metabolism
104527062 (GCLC)
09140 Cellular Processes
09143 Cell growth and death
04216 Ferroptosis
104527062 (GCLC)
Enzymes [BR:
acar01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.2 glutamate---cysteine ligase
104527062 (GCLC)
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Ortholog
Paralog
GFIT
Motif
Pfam:
GCS
GCS2
SANT_DAMP1_like
Motif
Other DBs
NCBI-GeneID:
104527062
NCBI-ProteinID:
XP_010168980
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All DBs
Position
Unknown
AA seq
583 aa
AA seq
DB search
MLVKFDHENKKVRLALCGEEVLQTLQDKGEKVNPNHPTLWRPEYGSYMIEGTPGQPYGGT
MSEFNTVQDNMRKRRQEAASVLKENEAVCTVTSFPRLGCPGFTLPEYKPTPVEGGASKSL
FFPDEAINKHPRFSTLTRNIRHRRGEKVVINVPIFKDKNTPSPFIETFPNDDGEAAKAAK
PDYIYMDAMGFGMGNCCLQVTFQACSISEARYLYDQLATICPIVMALSAASPFYRGYVSD
IDCRWGVISASVDDRTREERGLEPLKNNHYRISKSRYDSIDSYLSECGEKYNDIDLTIDK
DIYEHLIKEGIDHLLAQHIAHLFIRDPLTLFEEKIHLDDANESDHFENIQSTNWQTMRFK
PPPPNSDIGWRVEFRPMEVQLTDFENSAYVVFVVLLTRVILSYKLDFLIPLSKVDENMKV
AQKRDAVRQGMFYFRKDICKGGNAVVDGCSSAQNGTGTDTEEYTLMSIDTIINGKEGVFP
GLIPILNSYLENMEVDVDTRCTILNYLKLIKKRASGELMTVARWMREFIAQHPDYKQDSV
ITDEMNYSLIWKCNQIAQGQAECPELLGVGFNKKQSGNKTDFL
NT seq
1752 nt
NT seq
+upstream
nt +downstream
nt
atgttagtaaaatttgaccatgagaataagaaagtacgcttggcgctctgcggcgaagaa
gttcttcaaacactgcaagacaagggggagaaggtaaaccccaaccacccaacactctgg
cgaccagaatatggaagctatatgattgaagggacgcctgggcagccgtatggcggaacc
atgtctgaattcaacactgtgcaagacaacatgaggaaaagacggcaagaggccgcttct
gtgctcaaagaaaatgaggctgtttgcactgtgacatcatttccaaggttagggtgtcct
gggtttacgctgccagaatacaagccaacaccagtagaaggaggagcttcaaaatccctc
ttttttccagatgaagccatcaataaacatcctagatttagtacactgaccagaaacatt
cggcaccgaaggggagagaaggttgtgataaatgtaccaatatttaaagataagaacacg
ccatcaccgtttatcgaaacatttcctaatgatgatggagaagcagcaaaggcagctaag
ccagactatatctacatggatgctatggggtttggaatgggaaactgttgtcttcaggta
acattccaggcttgcagcatttctgaagcaagatatctctatgatcagctagccaccatc
tgtcccattgtgatggcattgagtgctgcgtctccgttctacagagggtacgtgtctgac
attgactgtcgctggggagtaatctctgcgtctgtagatgatcgaacacgagaagagagg
ggtctcgagccactgaagaacaaccattatagaatcagtaaatccagatatgattccata
gacagttatctatctgaatgtggtgagaaatacaatgacattgatttgacaatagacaaa
gatatctacgagcacctaataaaggaaggtattgaccaccttttggcacagcatattgca
cacttgttcattcgagacccattgactttgtttgaggagaagatacatctagatgatgca
aatgaatccgaccattttgagaatattcagtctacaaactggcagacaatgcggtttaag
ccacctcctccaaattcagatattggatggagagtagaattcagacctatggaggtccag
ttaacagactttgaaaactctgcgtatgttgtgtttgtggtgttgctaaccagagtgatt
ctgtcatataaactggattttctcattcctttgtccaaggtggatgaaaacatgaaggtg
gcccagaaaagggatgctgtccggcagggaatgttttacttcagaaaagatatttgcaaa
ggtggaaatgctgttgtggatggatgtagctctgcacagaacgggacaggcaccgacaca
gaagagtacaccttaatgagcattgatacaattatcaatgggaaggaaggagtctttcct
ggtttgatcccaattttgaattcctatcttgaaaacatggaagtggatgtggacacaagg
tgcaccatcttaaactacctgaagctaataaaaaagagagcatctggagaattaatgaca
gttgctcgatggatgagggaatttattgcacagcatccagactacaagcaagacagcgtg
ataactgatgaaatgaattacagccttatttggaaatgcaaccaaatcgcacaaggccag
gcagagtgtcctgaactattgggtgtgggatttaataagaaacaaagtggaaacaaaact
gactttttgtaa
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