KEGG   Aquarana catesbeiana (American bullfrog): 141112486
Entry
141112486         CDS       T11018                                 
Symbol
PLCB3
Name
(RefSeq) 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3 isoform X1
  KO
K05858  phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
Organism
acat  Aquarana catesbeiana (American bullfrog)
Pathway
acat00562  Inositol phosphate metabolism
acat01100  Metabolic pathways
acat04020  Calcium signaling pathway
acat04070  Phosphatidylinositol signaling system
acat04081  Hormone signaling
acat04082  Neuroactive ligand signaling
acat04261  Adrenergic signaling in cardiomyocytes
acat04270  Vascular smooth muscle contraction
acat04310  Wnt signaling pathway
acat04371  Apelin signaling pathway
acat04540  Gap junction
acat04621  NOD-like receptor signaling pathway
acat04912  GnRH signaling pathway
acat04916  Melanogenesis
Module
acat_M00130  Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Brite
KEGG Orthology (KO) [BR:acat00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    141112486 (PLCB3)
 09130 Environmental Information Processing
  09132 Signal transduction
   04310 Wnt signaling pathway
    141112486 (PLCB3)
   04371 Apelin signaling pathway
    141112486 (PLCB3)
   04020 Calcium signaling pathway
    141112486 (PLCB3)
   04070 Phosphatidylinositol signaling system
    141112486 (PLCB3)
  09133 Signaling molecules and interaction
   04082 Neuroactive ligand signaling
    141112486 (PLCB3)
   04081 Hormone signaling
    141112486 (PLCB3)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04540 Gap junction
    141112486 (PLCB3)
 09150 Organismal Systems
  09151 Immune system
   04621 NOD-like receptor signaling pathway
    141112486 (PLCB3)
  09152 Endocrine system
   04912 GnRH signaling pathway
    141112486 (PLCB3)
   04916 Melanogenesis
    141112486 (PLCB3)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    141112486 (PLCB3)
   04270 Vascular smooth muscle contraction
    141112486 (PLCB3)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:acat04131]
    141112486 (PLCB3)
Enzymes [BR:acat01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.4  Phosphoric-diester hydrolases
    3.1.4.11  phosphoinositide phospholipase C
     141112486 (PLCB3)
Membrane trafficking [BR:acat04131]
 Exocytosis
  Calcium ion-dependent exocytosis
   Phospholipases
    141112486 (PLCB3)
 Endocytosis
  Macropinocytosis
   Phospholipase C
    141112486 (PLCB3)
SSDB
Motif
Pfam: PI-PLC-X PLC-beta_C PH_14 PI-PLC-Y PLCB1-4-like_EFh EF-hand_like C2 FAM195 PH_12
Other DBs
NCBI-GeneID: 141112486
NCBI-ProteinID: XP_073461454
LinkDB
Position
LG11:complement(220429826..220674032)
AA seq 1211 aa
MAGARPGVHSLQLEPVQVPEILQRGSKFIKWDEENSSKSLVTLRVDSMGFYLYWTCPNME
VDILDITLIRDTRTGKYAKIPKDSRMREILGFASAEQRPEDKLVTVVYGTDMVNVNFLNF
MAVQEDTAKIWTEGLFKLATNILAQNSPRNAFLQKAYTKLKFQVNQDGRIPVKNILKMFA
ADKKRVETALESCGLNFNRGESIKPEEFTLEIFERFLNKLCLRPDIDKILIENGAKGKPY
LTLEQLMEFINQKQRDPRLNEILFPPLKRDQVRQLIEKYEPNRQFLERDQISMEGFSRFL
GGDENSIVPPEALDLSDDMTQPLTSYFINSSHNTYLTAGQLTGNSSVEMYRQVLLTGCRC
IELDCWKGRPQDEEPFITHGFTMTTEIPFKEVIEAIAESAFKTSPFPVILSFENHVDSAK
QQAKMAEYCRNIFGDALLTEPLEKYPLQPGFSLPSPQELLGRILVKNKKRHRVGAKGPEG
SVKRRVSEQPSNTYSDSSSICDSPAVGTLNSDSADVSLTLSNGDEQIEERIPKCVEPRKS
IDRDAYSEEEEDEEPSDPKKSDEGTASSEVSATEEMSNLVNYVEPVKFKSFDVANKRNKY
YEMSSFVETKALEQLTKSPMEFVEYNKKQLSRIYPKGTRVDSSNYMPQVFWNAGCQMAAL
NFQTLDLAMQLNMGIFEYNRRSGYLLKPEFMRRTDKPFDPFTENIVDGIVANTVKIKIIS
GQFLSDKRVGIYVEVDMFGLPVDTKRKYKTKTSQGNSFNPVWDEEPFEFPKVVLPTLASL
RIAVFEEGGKFVGHRILPVSAIRPGYHYICLRNEINQPLCLPALLVYTEVNDYIPDNHQE
YIKALMFPTQHVSLDERAKKLVALIGDTELSNADKPQEKKKTEIASVTPQIPTGIKKQSI
TPLSPIAHRDDLIASVLTDVQAPSLEELKLQKSFVKLLCRQYRELRHMHRKHLRKVSSLS
KEQNSRVIQLQSIRKKRFGKSQKGGQDLLSEQEEQQKKLLDLQGEQQRRLLEMRELQHEQ
ERKIKHIHLQQDILKLLDVAQSCHTAQLKKLKEINEKEKKELQKILDRKRHNSITEAKSR
DRQKKDGELTEINRRHINESVNFLRSLEEAQKRRQEKLLAAHQDTIQRIKDEEPKLMAQL
EEECQAEFRQLPQEVQRYLQEEGGNWGGGSSGPPSSTQSTPSSITRGWGSELGDGDHLQT
PEDSSDEATRL
NT seq 3636 nt   +upstreamnt  +downstreamnt
atggcgggggcccggccgggggtacactctctgcagctggagccggtgcaggtaccggag
attctacaacggggcagcaagttcatcaagtgggacgaggaaaatagcagcaagtctttg
gttacccttcgcgtggacagcatgggattttatctctactggacttgtccaaacatggaa
gttgatattttagatataaccctaatccgagacacgcggacaggaaagtatgctaagata
ccaaaggactctcgaatgagggaaattttaggctttgcatcagctgagcaacgtcccgaa
gataaactagttacagtcgtatatggcactgacatggttaacgtcaacttcctcaacttc
atggctgttcaggaggatacagcaaaaatttggacagaaggactttttaaattggccaca
aatattttggcacagaattcacctcggaacgcgtttctgcaaaaagcgtacaccaaattg
aaattccaggtgaatcaagatgggcgaataccagtcaagaacattcttaagatgtttgct
gctgacaagaaaagagtagagactgcactggagtcctgtgggctgaactttaatcggggt
gagtccatcaaaccagaggaatttacccttgaaatttttgaacgatttctgaataagcta
tgcctacggccagatattgataagattctcatagagaatggagctaaagggaagccatat
ttaactctggagcaactaatggaatttataaaccagaaacaaagggatccaaggctcaat
gagatccttttcccacctcttaaaagggaccaggtgcgccagcttattgaaaaatacgag
cccaacagacagtttcttgaaagagaccagatatctatggaaggttttagtcgtttcctg
ggtggggatgaaaacagcattgttcctccagaggccttggatctcagtgatgacatgaca
cagccgctcaccagttactttatcaactcctcccacaatacctacctcactgctggtcag
ctgacagggaactcatcagtagagatgtacagacaggtgctgctcacaggctgccgttgt
atcgagttggactgctggaaaggacgccctcaagatgaagaaccctttattactcatgga
tttaccatgaccactgagataccttttaaggaagtaattgaagcaatagcggaaagtgcc
ttcaaaacttccccatttccagtcattttatcctttgaaaatcatgttgactcagcaaag
caacaagctaagatggctgaatactgcagaaacatctttggcgatgcacttcttactgaa
ccgctagaaaaatatcctctccagccaggattttctcttccaagcccacaagaactgctg
gggaggatcttagtaaagaataaaaaaaggcacagagtgggggcaaagggtcctgaagga
agtgtgaaaagaagagtcagcgaacagccatccaatacttacagtgactcctccagcatc
tgtgattcacctgcagtaggtactttgaactctgactcagctgatgtttctctgacactt
tctaatggagatgaacaaatagaggagaggatccccaagtgtgtagagccacggaaatcc
atagaccgtgatgcttatagtgaggaggaggaagatgaagagccttctgaccctaaaaag
tcagacgaaggcactgctagcagtgaagtcagtgccaccgaagaaatgtccaatcttgtt
aactacgtggaacctgtaaagttcaagtcatttgatgtggccaacaagaggaataaatat
tatgaaatgtcttcatttgttgagactaaggcactggagcagctaacgaaatctcccatg
gagtttgtggaatataataagaagcagctaagccgtatctatccgaaaggaactagagtg
gattcttctaattacatgccacaagttttctggaatgcaggatgtcagatggctgcattg
aattttcaaacactggacctggcaatgcagctgaatatggggatatttgaatataaccgg
cgcagtgggtaccttctaaagccagaattcatgcgtaggactgataaaccctttgatcct
ttcacagaaaatattgttgatgggattgtggcaaatactgtaaaaattaagattatctca
ggccagttcctgtctgataaacgtgttggaatatatgtagaggttgatatgtttggtttg
cctgttgacacgaaaagaaagtataagacaaaaacatcccaaggaaactcttttaaccct
gtgtgggacgaggagccatttgaattcccaaaggtggtgctacctacacttgcctctctt
cgcattgctgtgtttgaagaaggtggaaagtttgttggtcacaggattctgccagtgtct
gcaatacgaccaggttatcactacatctgtctcaggaatgaaattaatcagcctctatgt
ctcccggctttgcttgtctataccgaagtaaatgactatattcctgataaccatcaagag
tacatcaaagctctgatgttccccacccaacatgtcagtctggatgagagggccaagaaa
cttgtggctctgattggagacactgagctgagcaatgcagataaaccacaagagaagaaa
aagactgaaatagcaagtgtcactcctcagatacctacaggtatcaagaagcaatccatt
acacctctatcacctatagctcaccgggatgaccttatagcaagtgtactaacagatgta
caagcaccatccttggaggagctaaagttacagaaaagctttgtgaaattgctttgtcgg
cagtaccgggaattgcgtcacatgcaccgcaagcacctacgcaaagtatcctccttgtcc
aaggagcagaacagcagagtcatacagctgcagagcatacgaaagaagagatttgggaaa
agtcaaaaaggcggacaagatttgctctcagagcaggaggagcagcagaagaagctgctg
gacctacaaggggagcagcagaggcgccttctggagatgagggaacttcaacatgagcaa
gaacgtaaaatcaaacacatccacttgcagcaggacattctgaagctgctggacgtagct
cagtcgtgccatactgctcagctgaagaaattaaaagaaatcaatgaaaaggagaagaaa
gaattacaaaagattctggacagaaagagacataatagcatcaccgaggccaagtcacga
gaccgtcaaaagaaggatggagaactcactgagattaacagacgtcacatcaatgagtcg
gtgaactttctacgcagtttagaagaagcacaaaagagacgtcaggaaaagttactagca
gctcaccaggacacaatacagaggataaaggatgaggagcctaagctgatggcccaattg
gaagaggagtgccaagctgaattccgacagttaccccaagaagttcagcgatatctgcaa
gaagagggaggcaattggggtggggggagttcaggtccgccatcttctacacagagcacc
ccttcttctatcacacgtggctggggatcagagcttggagatggggatcatttacagacc
ccagaggactcaagtgatgaagctactcgactttga

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