Aquila chrysaetos chrysaetos (golden eagle): 115351024
Help
Entry
115351024 CDS
T08023
Symbol
GCLC
Name
(RefSeq) glutamate--cysteine ligase catalytic subunit isoform X3
KO
K11204
glutamate---cysteine ligase catalytic subunit [EC:
6.3.2.2
]
Organism
achc
Aquila chrysaetos chrysaetos (golden eagle)
Pathway
achc00270
Cysteine and methionine metabolism
achc00480
Glutathione metabolism
achc01100
Metabolic pathways
achc01240
Biosynthesis of cofactors
achc04216
Ferroptosis
Module
achc_M00118
Glutathione biosynthesis, glutamate => glutathione
Brite
KEGG Orthology (KO) [BR:
achc00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
115351024 (GCLC)
09106 Metabolism of other amino acids
00480 Glutathione metabolism
115351024 (GCLC)
09140 Cellular Processes
09143 Cell growth and death
04216 Ferroptosis
115351024 (GCLC)
Enzymes [BR:
achc01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.2 glutamate---cysteine ligase
115351024 (GCLC)
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
GCS
GCS2
SANT_DAMP1_like
zf_topless
Motif
Other DBs
NCBI-GeneID:
115351024
NCBI-ProteinID:
XP_029893147
Ensembl:
ENSACCG00020009005
UniProt:
A0A663EMI4
LinkDB
All DBs
Position
15
Genome browser
AA seq
636 aa
AA seq
DB search
MGLLSQGSPLSWEETRRHAEHVRKHGILQFLHIYRALRDRHKDVLKWGDEVEYMLVKFDH
ENKKVRLVLCGEEVLQTLQDKGEKVNPNHPTLWRPEYGSYMIEGTPGQPYGGTMSEFNTV
QDNMRKRRQEAASVLKENEAVCTVTSFPRLGCPGFTVPEYKPTPVEGGASKSLFFPDEAI
NKHPRFSTLTRNIRHRRGEKVVINVPIFKDKNTPSPFIETFPNDDGEAAKAAKPDYIYMD
AMGFGMGNCCLQVTFQACSISEARYLYDQLATICPIVMALSAASPFYRGYVSDIDCRWGV
ISASVDDRTREERGLEPLKNNHYRISKSRYDSIDSYLSECGEKYNDIDLTIDKDIYEHLI
KEGIDHLLAQHIAHLFIRDPLTLFEEKIHLDDANESDHFENIQSTNWQTMRFKPPPPNSD
IGWRVEFRPMEVQLTDFENSAYVVFVVLLTRVILSYKLDFLIPLSKVDENMKMAQKRDAV
RQGMFYFRKDICKGGNTVVDGCGSAQNGTGTDAEEYTLMSIDTIINGKEGVFPGLIPVLN
SYLENMEVDVDTRCTILNYLKLIKKRASGELMTVARWMREFIAQHPDYKQDSMITDEMNY
SLIWKCNQIAQGQAECPELLGVGFNKKQSGNKTGSL
NT seq
1911 nt
NT seq
+upstream
nt +downstream
nt
atggggctgctgtcgcagggctcgccgctgagctgggaggagacgcggcggcacgcggag
cacgtgcggaagcacggcatcctccagttcctccacatctaccgcgccctgcgcgaccgc
cacaaggacgtcctcaagtggggcgacgaggtggaatatatgttagtaaaatttgaccat
gagaataagaaagtgcgcttggtgctctgcggtgaagaagttcttcaaacactgcaagac
aagggggagaaggtaaaccccaaccacccaacactctggcgaccagaatatggaagctac
atgatagaagggacgcctgggcagccgtatgggggaaccatgtctgaattcaacactgtg
caagacaacatgagaaaaagacggcaagaggccgcttctgtgctcaaagaaaatgaggct
gtttgtactgtgacgtcatttccaaggttagggtgtcctgggtttacggtgccggaatat
aagccaacgccagtagaaggaggagcttcaaaatccctttttttcccagatgaagccatc
aataaacatcctagatttagtacactgaccagaaacattcggcaccgaagaggagagaag
gttgtgataaatgtaccaatatttaaagataagaacacgccatcaccgtttatcgaaacg
tttcctaatgatgatggagaagcagcaaaggcggctaagccagactatatatacatggat
gctatggggtttggaatgggaaactgctgtcttcaggtaacattccaggcttgcagcatt
tctgaagcgaggtatctctatgatcagctagccacgatctgtcccattgtgatggcgttg
agtgctgcgtctccattctacagaggctacgtgtctgatattgactgtcgctggggagta
atctctgcatctgtagatgatcgaacgcgagaagagagggggctagagccactgaagaac
aaccattatagaatcagtaaatccagatatgattccatagacagttatctatctgaatgt
ggtgagaaatacaatgacattgatttgacaatagacaaagatatctacgagcacctaata
aaggaaggtattgaccaccttttggcacagcatattgcacacttgttcattcgagaccca
ttgacgttgtttgaggagaaaatacatctagatgatgcaaatgaatccgaccattttgag
aatattcagtctacaaactggcagacaatgaggtttaagccacctcctccaaattcagat
attggatggagagtggaattcagacctatggaggtccagttaacagactttgaaaactct
gcatatgttgtgttcgtggtactgctaaccagagtgattctgtcatataaactggatttt
ctcattcctttgtccaaggtggatgaaaacatgaagatggcccagaaaagagatgctgtc
cggcagggaatgttttacttcagaaaagatatttgcaaaggtggaaacactgttgtggat
ggatgtggctctgcacagaatgggacaggcaccgatgcggaagagtacaccttaatgagt
attgatacaattatcaatgggaaggaaggagtctttcctggtttgatcccagttttgaat
tcctatcttgaaaacatggaagtggatgtggacacaaggtgcaccatcctaaactacctg
aagctaataaaaaagagagcatctggagaattaatgacagttgctcggtggatgagggaa
tttatcgcacagcatccagactacaagcaagatagcatgataactgatgaaatgaattat
agccttatttggaaatgcaaccaaatcgcacaaggccaggcagagtgtcctgaactattg
ggggtaggatttaacaagaaacaaagtggaaacaaaactggctctttgtaa
DBGET
integrated database retrieval system
