Acanthisitta chloris (rifleman): 103797554 Help Entry 103797554         CDS       T08456                                  Symbol RYR2 Name (RefSeq) ryanodine receptor 2   KO K04962   ryanodine receptor 2 Organism achl  Acanthisitta chloris (rifleman) Pathway achl04020   Calcium signaling pathway achl04260   Cardiac muscle contraction achl04261   Adrenergic signaling in cardiomyocytes achl04371   Apelin signaling pathway Brite KEGG Orthology (KO) [BR:achl00001]  09130 Environmental Information Processing   09132 Signal transduction    04371 Apelin signaling pathway     103797554 (RYR2)    04020 Calcium signaling pathway     103797554 (RYR2)  09150 Organismal Systems   09153 Circulatory system    04260 Cardiac muscle contraction     103797554 (RYR2)    04261 Adrenergic signaling in cardiomyocytes     103797554 (RYR2)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04040 Ion channels [BR:achl04040]     103797554 (RYR2)    04990 Domain-containing proteins not elsewhere classified [BR:achl04990]     103797554 (RYR2) Ion channels [BR:achl04040]  Voltage-gated cation channels   Ryanodine receptor    103797554 (RYR2) Domain-containing proteins not elsewhere classified [BR:achl04990]  EF-hand domain-containing proteins   Other EF-hand domain-containing proteins    103797554 (RYR2) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  RYDR_Jsol RYDR_ITPR RyR RR_TM4-6 SPRY MIR Ins145_P3_rec RIH_assoc EF-hand_7 EF-hand_1 EF-hand_8 EF-hand_6 Motif Other DBs NCBI-GeneID:  103797554 NCBI-ProteinID:  XP_009068059 LinkDB All DBs Position Unknown AA seq 4714 aa AA seqDB search DDEVVLQCTATVQKEQQKLCLAAEGFGNRLCFLESTSNSKNVPPDLSICTFVLEQSLSVR ALQEMLANTEEKAEGLVDVEKWRFTSKSAQGGGHRTLLYGHAILLRHSYSGMYLCCLSTS RSSMDKLAFDVGLQEDTTGEACWWTIHPASKQRSEGEKVRVGDDLILVSVSSERYLHLSY GNGSLHVDAAFQQTLWSVAPISSGSEVAQGYLIGGDVLRLLHGHMDECLTVPSGEHGEEQ RRTVHYEGGAVSSHARSLWRLETLRVAWSGSHIRWGQPFRLRHITTGKYLSLLDDKSLLL TDKEKADVKSTAFCFRSSKEKLDIGTRKEVDGMGAPEIKYGDSMCFIQHVDTGLWLTYQS ADAKSVRMGSVQRKAIMHHEGHMDDGLTLSRSQNEESRTARVIRSTVFLFNRFIRGLDAL SKKAKSSTVDLPIESVSLSLQDLIGYFHPPDEHLEHENKQNRLRALKNRQNLFQEEGMIN LVLECIDRLNVYSSAAHFADVAGKEAGEAWKSILNSLYELLAALIRGNRKNCAQFSGSLD WLISRLERLEASSGILEVLHCVLVESPEALNIIKEGHIKSIICLLDKHGRNHKVLDVLCS LCVCHGVAVRSNQHLICDNLLPGRDLLLQTRLVNHVSSMRPNIFLGISEGSAQYRKWYYE LMVDHLEPFVTAESTHLRVGWASTEGYSPYPGGGAEWGGNGVGDDLYSYGFDGLHLWSGC VARTVNSPNQHLLRTDDVISCCLDLSAPSISFRINGQPVQGMFENFNIDGLFFPVVSFSA GIKVRFLLGGRHGEFKFLPPLGYAPCFEAVLPKEKLKVEHSREYKQDRSYTRDLLGPTVS LSQAAFTPVPVDTSQIVLPPHLERIREKLAENIHELWVMNKIELGWQYGPVRDDNKRQHP CLVEFSKLPEQERNYNLQMSLETLKTLLALGCHVGIADEHAEEKVKKMKLPKNYQLLSGY KPAPMDLSFIKLTPSQEAMVDKLAENAHNVWARDRIRQGWTYGIQQDVKNRRNPRLVPYA LLDDRTKKSNKDSLREAVRTLLGYGYNLEAPDQDHATRLDVCSGIMEKYRIFRTEKTYAV KTGKWYFEFEAVTAGDMRVGWTRPGCLPDQELGSDEEAFVFDGFKAQRWHQGNEHFGRSW SSGDVVGCMVDMNEHTMMFTLNGEILLDDSGSELAFKDFELGDGFLPVCSLGPSQVGRMN FGKDVSTLKYFTICGLQEGYEPFAVNTNRDITIWLSKRLPQFLPVPQNHEHIEVTRIDGT IDSCPCLKVTHKSFGSQNSKTDVMFFRLSMPIECAEVFSRSVAGGLPGSGLFGPKNDLED YDADSDFEVLMKTAHGHLVPDRTEREKDATKPELNNHKDYVQEKPSRLKQRFMLRRTKPD YSTSHSARLTEDVLADDRDDYDYLMQTSTYYYSVRIFPGQEPANVWVGWITSDFHQYDTS FDLDRVRTVTVTLGDEKGKVHESIKRSNCYMVCAGESMSPGQGRNNNGLEIGCLVDAASG LLTFTANGKELGTYYQVEPSTKLFPAVFAQATSPNVFQFELGRIKNVMPLSAGLFKSEHK NPVSQCPPRLHVQFLTHVLWSRVPNHFLKVDVSRISERQGWMIQCLNPLQFMALHIPEEN RTIDILELTEQEELLRFHYHTLRLYSAVCALGNNRVAHALCSHVDESQLLYAIENKYMPG LLRAGYYDLLIDIHLSTYATARLMMNNEFIVPMTDETKSITLFPDENKKHGLPGIGLSTS LRPRMQFSSPSFVSISSECFQFSPEFPLEILKAKTIEMLTEAVQEGSLHVRDPVGGSTEF LFVPLIKLFYTLLIMGIFHNEDLKHILQLIEPRVFKEARSHEDEIDFSEKELSSDEFKSE EGEEETRGEQMPKEGLLQMKLPEPVKLQMCHLLQYLCDCQVRHRIEAIVAFSDDFVAKLQ ENQRFRYNEVMQALNMSAALTARKTKEFRSPPQEQINMLLNFKDDKNECPCPEEIRDHLL DFHEDLMTHCGIELEEDGTSDGNSDLTIRGRLLYLMEKVTYLKKKQAEKPVDDDANTSST LQQLISETMVRWAQESVIEDPELVRAMFVLLHRQYDGIGGLVRALPKTYTINSVSVEDTI NLLASLGQIRSLLSVRMGKEEEKLMIRGLGDIMNNKVFYQHPNLMRALGMHETVMEVMVN VLGGGESKEITFPKMVANCCRFLCYFCRISRQNQKAMFDHLSYLLENSSVGLASPSMRGS TPLDVAAASVMDNNELALALREPDLEKVVVRYLAGCGLQSCPLLICKGYPDIGWNPVEGE RYLDFLRFAVFCNGESVEENANVVVRLLIRRPECFGPALRGEGGNGLLAAMEEAIQISED STRDGPSPSNGSSKALEIEEQEDDTIHMGNAIMTFYAALIDLLGRCAPEMHLIHAGKGEA IRIRSILRSLIPLEDLVGVISIPFHMPTIAKDGTVVEPDMSAGFCPDHKAAMVLFLDRVY GIEDQDFLLHLLEVGFLPDLRAAASLDTAALSATDMALALNRYLCTAVLPLLTRCAPLFA GTEHHASLIDSLLHTVYRLSKGCSLTKAQRDSIEECLLSICGQLRPSMMQHLLRRLVFDV PLLNEHTKMPLKLLTNHYERCWKYYCLPSGWGNFGAASEEELHLSRKLFWGIFDALSQKK YEQELFKLALPCLSAVAGALPPDYMESNYVNMMEKQSSMDSDGNFNPQPVDTSNITIPEK LEYFINKYAEHAHDKWSMEKFANGWTYGETFSESAKVQPLMKQYKLLSEKEKEIYRWPIK ESLKTMLAWGWRIERTREGDSMALYNRTRRISQTSQISVDTAHGYTPRAIDMSNVTLSRD LHAMAEMMAENYHNIWAKKKKMELEAKGGGNHPLLVPYDTLTAKEKAKDREKAQDILKFL QINGYVVSRGLKDLELDTPSIEKRFAYSFLQQLIRYVDEAHQYILEFDGGSRGKGEQFPY EQEIKFFAKVVLPLIDQYFKNHRLYFLSSASRPLSTGGHASNKEKEMVTSLFCKLGVLVR HRISLFGNDATSIVNCLHILGQTLDARTVMKTGLESVRMALRAFLDNAAEDLEKTMENLK QGQFTHSRNQPKGVTQIINYTTVALLPVLSSLFEHIGQHQFGEDLILEDVQVSCYRILAS LYALGTSKSIYVERQRSALGECLAAFSGAFPVAFLETHLNKHNIYSIYNTKNARDRAVLN LPASVEEVCPNIPSLVKLMEEIVELAESGIRYTQMPHIMEVILPMLCSYMSHWWEHGPEN NPDKAEMCCTALTSEHMNTLLGNILKIIYNNLGIDEGAWMKRLAVFSQPIISKAKPQLLK THFLPLMDKLKKKAAVVVSDEEHLRAEGRGDMSEAELLILDEFTTLARDLYAFYPLLIRF VDYNRAKWLKEPNPEAEELFRMVAEVFIYWSKSHNFKREEQNFVVQNEINNMSFLISDTK SKMSKAAVTDQERKKMKRKGDRYSLQTSLIVAALKRLLPIGLNICAPGDQELISLAKNRF SMKDTEDEVRDVIRSNLHLQGKLEDPAIRWQMALYKDLPNRAEDSSDPEKTVERVLDIAN VLFHLEQVEHPQRSKKAVWHKLLSKQRKRAVVACFRMAPLYNLPRHRAVNLFLQGYDKSW IETEEHYFEDKLIEDLAKPGEEPPEEDESLKRVDPLHQLILLFSRTALTEKCKLEEDYLY MAYADIMAKSCHDEEDDDGEEEVKSFEVTGSQRSKEKEMEKQKLLYQQARLHDRGAAEMV LQTISASKGEMGPMVAATLKLGIAILNGGNSTVQQKMLDYLKDKKDVGFFQSLAGLMQSC SVLDLNAFERQNKAEGLGMVTEEGSGEKVMQDDEFICDLFRFLQLLCEGHNSDFQNYLRT QTGNNTTVNIIISTVDYLLRVQESISDFYWYYSGKDVIDEQGQRNFSKAIQVAKQVFNTL TEYIQGPCTGNQQSLAHSRLWDAVVGFLHVFAHMQMKLSQDSSQIELLKELMDLQKDMVV MLLSMLEGNVVNGTIGKQMVDMLVESSNNVEMILKFFDMFLKLKDLTSSDAFKEYDPDGK GIISKRDFHRAMESHKHYTQSETEFLLSCAETDENETLDYEEFVKRFHEPAKDIGFNVAV LLTNLSEHMPHDTRLQTFLELSESVLNYFQPFLGRIEIMGSAKRIERVYFEISESSRTQW EKPQVKESKRQFIFDVVNEGGEKEKMELFVNFCEDTIFEMQLAAQISESDLNERSANKEE NEKDNPEEEDPRMGFFSLVTMKSALVALKYNLMTLMKMLSMKSLKKQMKKVKKMTMKDMV MALFSSYWSILMGLLHFAYSVVRGFFRIICSLLLGGSLVEGAKKIKVAELLANMPDPTQD EVRGEGEEGERKATEAALPTEDLTDLQTLSEESDLLSDIFGLDLKREGGQYKLIPHNPNA GLSDLLSTPSLAPMPEVQEKIQEQVKEDEKEEKEETKSEPEKAEGEDGEKEDKNKDDKGK LKLRQLHTHRHGEPEVQESVFWKNIIAYQQKLLNYFARNFYNMRMLALFVAFAINFILLF YKVSTSAVTEEKELPVVSAGESTKLNILESDDDRVIAVHYVLEESSGYMEPTLRILAILH TVISFFCIIGYYCLKVPLVIFKREKEVARKLEFDGLYITEQPSEDDIKGQWDRLVINTQS FPNNYWDKFVKRKVMDKYGEFYGRDRISELLGMDKAALDFSDAREKKKPKKDSSFSAVLN SIDVKYQMWKLGVVFTDNYSGLYLIYYMSELLGA NT seq 14145 nt NT seq  +upstreamnt  +downstreamnt gatgatgaagtggtcctgcaatgcactgctaccgttcagaaggagcaacagaaattgtgt cttgctgcagaaggatttggcaacaggctttgctttttggaatccacatcaaattctaag aatgttccacctgatttgtccatctgcacctttgtactggagcagtccctgtcagtacgt gccctccaggaaatgttggctaatacagaagaaaaggcagaagggctagttgatgtggaa aaatggagatttacaagtaagtcagcacaaggtggtggtcatcgaacgctactctatggg catgcaatcttgctgcgccattcctacagcggcatgtatctatgctgcctctctacatct cgatcttcaatggataagctggcatttgatgtaggattgcaagaggacacaacaggtgag gcatgctggtggaccatacatcctgcttccaaacaacgatcagaaggagaaaaagtgcgt gttggagatgatcttattttagtcagtgtctcttcagaaagatatttgcatctctcctat ggcaatggtagcttacatgttgatgcagccttccagcagacactctggagtgtagcacca atcagttcaggaagcgaagttgcccaaggttatctgataggaggggatgttctgaggtta ttgcatggtcacatggatgaatgtttgacggtcccttcgggtgaacatggagaagagcaa agaagaactgtccattatgaaggtggtgctgtgtccagtcatgctcgttccctttggcga ctagagactctaagagttgcgtggagtggcagccacattagatggggacagccattcaga ctaagacatataacaacaggaaaatatttaagtctcctggatgataagagtcttctgctt acagacaaagagaaggcggatgtaaaatctacagcattctgttttcggtcttccaaggaa aaactggacatagggacaagaaaagaggtggatggaatgggagcacctgaaataaagtat ggggattcaatgtgcttcatacaacatgtagatacaggcttatggctcacataccagtct gctgatgcaaagtctgtaagaatgggttctgtgcagcggaaggcaataatgcaccatgaa ggtcacatggatgatggtttaacactgtcaagatctcagaatgaagaatcccgtacagca cgtgtcatccgtagtacagtcttccttttcaacaggtttataaggggccttgatgctctc agcaagaaagcaaagtcttccaccgtcgatttgcctattgagtcagtcagtctgagcctt caggacttgattggctactttcacccccctgatgaacatttggagcatgaaaacaaacaa aacaggctccgagcactgaagaatcgccagaacctcttccaagaagagggtatgatcaac cttgttcttgaatgtattgatcgcttgaatgtatacagcagtgcagctcattttgcagac gtagctggaaaggaagctggagaagcatggaagtctattctgaattctttgtatgaatta ttagcggctctgattcgagggaatcgtaaaaactgtgctcaattttctggatctcttgac tggttgatcagcagattggaaagactggaagcctcctctggaattctagaagttttacac tgtgtgttggtagaaagcccagaagctctaaacattattaaggaaggacatattaaatca atcatctgtcttttggacaagcatggaagaaaccataaggttttggatgttttgtgttct ctctgtgtttgtcatggagtagctgtgcggtctaatcaacacctaatctgtgataatctc ctgccaggaagagatctgctcttacagactcgccttgtcaaccatgtcagcagcatgcga cccaacatcttcttggggattagtgaaggctctgcccaatacagaaaatggtactatgaa cttatggtggaccatctagaaccctttgtgactgcagaatcgactcatctacgagtgggc tgggcttcaacagaaggctactcaccatatccagggggaggagcagaatggggaggaaat ggtgttggtgatgacttatattcctatggctttgatggtctacatctgtggtcaggttgt gtagcacgaacggtaaattctcccaaccaacatctgttgagaactgacgatgttattagc tgctgtttggacctgagtgcccccagcatctccttccgaataaatggccagccagttcaa ggaatgtttgaaaatttcaacatagatggtctcttcttcccagttgtcagcttctctgca ggaataaaggtacggttcttgcttggaggtcgccatggagagttcaagttccttcctcca cttggatatgccccttgctttgaagctgtcctaccaaaagagaaactgaaagtggagcat agccgggagtacaaacaagatcgtagctataccagagacctactgggtcccactgtctct ctgtcacaagcagctttcactccagttcctgtagatactagccagattgttttgcctccc cacctggaaaggattagagaaaaattagcagagaacatccatgaactttgggttatgaat aagattgaacttggatggcagtatggaccagttagagatgacaacaaaagacaacacccg tgcttagtggagttctcaaaattgccggagcaagaaagaaattataacttacaaatgtca cttgaaacattgaaaaccctactggcgttaggctgccatgttggaattgctgatgaacat gcggaagaaaaagtgaaaaaaatgaaacttccaaagaactatcagttgttgagtggatat aagcctgcacccatggatctgagttttatcaaactgacaccctctcaagaagctatggtg gataaactagcagagaatgctcacaatgtgtgggcaagggaccgtataaggcaaggctgg acttatggtatccagcaggatgtgaaaaatcgacgaaatcctcgcctggttccttatgct ctcttggatgatcgaacgaagaagtcaaacaaagacagtcttcgtgaagcagtccgcacc cttctaggctatggttataatctggaagctcctgatcaagatcatgcaacaagactggat gtgtgcagtgggataatggaaaagtacaggatcttccgcacagaaaagacttatgcagtg aagactgggaagtggtactttgagtttgaggcagttactgcaggagacatgagagttggc tggactaggccaggttgtctgccagatcaggaacttggttcagatgaagaagcttttgtt tttgatggctttaaggcacagcggtggcatcagggtaatgaacattttggccgctcttgg tcgtcaggagatgttgttggatgtatggttgacatgaatgagcacactatgatgttcact ttaaatggtgaaatcctgcttgatgactcaggttcagaacttgcattcaaggacttcgag ctgggtgatggatttctacctgtgtgcagcctgggaccatctcaagtgggaagaatgaac tttggaaaagatgtcagcactctaaaatatttcactatctgtggcttacaggaagggtat gaaccctttgctgttaatacaaacagagacatcaccatttggctgagtaaaaggctccct cagtttctaccagtgccacaaaatcatgaacatattgaggtgacaagaattgatggcacc atagacagctgcccctgtctgaaggtcacacacaaatcctttggttcacagaacagtaaa acagatgtcatgttttttcgattaagcatgcccattgaatgtgctgaggtgttctccaga tcagttgcaggaggcttaccaggctctggtctgtttggcccaaagaatgatttggaggat tatgatgctgattctgattttgaggttctaatgaaaactgctcatggtcatttagttcct gaccggacagaaagagaaaaagatgccacaaaaccagagttaaacaaccataaagattat gttcaagaaaagccttcacgtcttaaacaaagatttatgctcaggaggacaaagccagat tatagcaccagtcactctgcacggcttactgaggatgtgctagcagatgatagggatgac tatgattatttgatgcaaacttccacgtactactattcagtgagaatatttcctggtcaa gaacctgctaatgtctgggtgggctggattacatctgactttcaccagtatgacacaagc tttgacttggacagagtgcgtaccgtgacagttacactgggagatgaaaaaggaaaggtt catgagagtataaaacgcagcaactgctatatggtgtgcgcaggagagagcatgagccct ggacaaggacgtaataataatggtctggagattggttgcttggttgatgctgccagtggc ctgctgaccttcacagctaatggcaaggaactaggcacatactatcaagttgaaccaagt acaaagttgtttcctgctgtatttgctcaagctacaagcccaaatgttttccagtttgaa ttgggaagaataaagaatgtaatgccattatctgctggcttatttaaaagtgaacacaaa aacccagtttctcaatgtcctccacgtctccatgtccaatttctgactcatgtgctttgg agcagagtgccaaaccacttcttgaaggttgatgtgtctcgaatcagtgaacgtcaaggc tggatgatacagtgtctgaatcctttgcagttcatggcccttcatattcctgaagaaaac agaacaattgatattttagagctgacagaacaagaagaattgctgagatttcactatcat accctccgattatattcagctgtttgtgctttaggcaacaaccgagtggcccatgctctg tgtagtcatgtggatgaatctcagctgctctatgctattgagaataaatacatgccagga ttattacgtgcaggatattatgacttactcattgacatccatctcagtacctatgcaact gccagattaatgatgaataatgaattcatagttccaatgacagatgaaaccaagagtata actttgtttcctgatgaaaacaaaaaacatggcctccctggtataggactgagcacttca ttaaggccaagaatgcagttctcctctccaagttttgtaagcattagcagtgaatgcttt cagtttagtcctgaattcccactggaaattttgaaggccaaaaccatagagatgctgact gaagctgttcaggagggaagcctccatgtcagagatccggttggaggttctacagaattt ctatttgtccctctcatcaagctcttttatactcttttaattatgggaatcttccacaat gaggatctgaaacacatattgcagttgattgagccccgggttttcaaagaagcaaggagc catgaggatgaaattgatttctcagagaaggagttgagttcagatgagttcaagtcagaa gaaggagaggaagaaaccagaggggagcaaatgccaaaggaaggactccttcagatgaaa cttccagaacctgttaaattacagatgtgtcatctactccagtacctatgtgactgccaa gtacgacaccgaatagaagccattgtagcattttcggatgattttgtggccaagcttcag gagaatcaacgcttccggtataatgaagtgatgcaggccttgaacatgtctgctgccctg acagctagaaaaaccaaagaatttcgatccccacctcaggagcagattaacatgctgctg aactttaaagatgataaaaatgaatgtccttgccctgaagaaattcgggatcatctcttg gatttccatgaagacctaatgacacactgtggaattgaactagaagaagatggaacctca gatggcaacagtgatttaaccattaggggccgcctcctataccttatggaaaaagttaca tatctgaagaagaagcaagctgagaagccagttgacgatgatgctaatacatcctctact cttcagcagttgatttcagagacaatggtacgctgggcccaggaatcagttatagaagat ccagagttagtgagggccatgtttgtattgctacatcgccagtatgacggtatcggtggc ctggttcgagctctgccaaagacctacaccataaacagtgtgtctgtggaagacacaatc aatcttctcgcatcccttggccaaatccgttccttgcttagtgtcagaatggggaaggag gaggagaaacttatgattcgtggattgggagacatcatgaataataaagtattttaccaa catccaaatctcatgagagctttaggcatgcatgaaactgtcatggaagtgatggtaaat gtgcttggtggaggagaatccaaggaaatcactttcccaaagatggtggcaaactgctgt cgttttctgtgttacttttgccgcatcagcaggcagaatcaaaaagctatgtttgatcat cttagctatttattggaaaacagcagtgttggccttgcctctccttctatgcgaggatca actcctttagatgttgcagcagcatctgtgatggataacaatgagcttgcactggcttta agggagcctgatctggagaaggtggtggttcgctacttggctggatgtggattgcagagt tgtcctttgttgatttgtaagggctacccagacatcggatggaatccagttgaaggagaa cgatacttggattttcttcgtttcgctgttttttgcaatggagagagtgtggaggagaat gctaatgttgtagtcagactgcttattcgccgacctgagtgttttggtccggctctaaga ggagaaggaggtaatgggttacttgctgccatggaggaagcaatacagatatccgaagat tcaacaagagatggaccttccccaagtaatggatctagtaaagcccttgaaatagaagaa caagaagatgacacaattcacatgggaaatgcaatcatgaccttttatgctgctttaatt gatctcttaggacgttgtgcccctgaaatgcatctaatccatgctggtaaaggggaagcc attagaatcagatcaattctacggtctttgattccactagaagatttggtgggagtaatt agtattcctttccacatgccaaccatagctaaagatggtactgtggtggaacctgacatg tctgcggggttttgcccagatcacaaggcagccatggttttgttccttgacagggtctat ggaattgaagaccaggattttcttctacaccttcttgaagttggctttctgccagatctt cgtgctgctgcatctttagatacggctgctttaagtgctacagatatggctttggctctg aatcgatacctttgcacagcagtcttgcctctcttgaccagatgtgctcctctttttgct ggcacagagcaccatgcttccctcattgattccttattacatactgtgtacagactctca aagggatgctctcttaccaaggctcagcgagattctattgaagagtgtttgctgtctatt tgtgggcagttgcggccttccatgatgcagcatttgctgagaagattagtatttgatgtt cctctattaaatgaacatacaaagatgcctctgaagttgctgacaaatcattatgaaaga tgctggaagtattactgtttgccaagtggatggggtaactttggtgctgcctcagaagaa gaacttcatttatccagaaagttgttctggggtatttttgatgctttatctcaaaagaag tatgaacaagaactgttcaaactggctttgccttgtctgagtgcagttgcaggggcctta cctccagattatatggaatcaaattatgtcaatatgatggaaaaacagtcttcaatggat tcagatgggaactttaatcctcaacctgttgatacctcaaacattacaatccctgaaaag ctagaatatttcattaacaaatatgcggaacatgctcatgacaaatggtcaatggaaaag tttgccaatggttggacatacggtgaaacattttctgaatctgcaaaagtgcaaccatta atgaaacaatataagttactatctgaaaaggaaaaagaaatttatcgatggccaatcaaa gaatctctaaaaactatgctggcgtggggatggcgaattgaaaggacacgtgagggagat tccatggcgctgtataatcggacacgtcgcatatctcaaaccagtcaaatctctgtagat acagcccatggttacactcctcgagcaattgacatgagcaatgtcaccctctccagagac ttacatgctatggctgagatgatggctgaaaactaccataacatatgggcaaagaaaaag aaaatggagcttgaagcaaaaggaggaggcaaccatcctcttcttgttccgtatgataca ctcacagccaaagaaaaagccaaggacagagaaaaagcacaggatattctgaaatttcta cagattaatggatatgttgtctccagaggacttaaggacctggaattagacacaccttcc attgagaaacgctttgcctacagtttccttcaacagcttataagatatgtggatgaagcc catcagtacattctggagtttgatggtggcagcagaggcaaaggagagcagttcccatat gaacaagaaatcaagttttttgccaaagttgtgcttcctttgattgatcagtattttaaa aatcatcgcctgtatttcttatcttcagcaagtaggcctctcagcactggaggccatgcc tctaataaagagaaagaaatggtcacaagcctgttctgcaaacttggagttcttgtcagg cataggatttcactgtttggaaacgatgcaacatcaatagtcaactgtcttcacatcctg ggccagaccttggatgcaaggactgtgatgaaaactggcctggaatctgttaggatggca ttgagagcttttttggacaatgctgctgaggatctggagaaaacaatggaaaatcttaag caaggccagtttacacacagcaggaaccagccaaaaggagttacacaaatcatcaattat accacagtcgctctcctgcctgtgctgtcttcattgtttgagcatattggacagcaccag tttggggaagatttgatattggaagatgttcaggtctcctgttacagaatattggccagt ttatatgctctgggaaccagcaagagtatctatgtggagcggcaacgatcagcactagga gaatgtttggctgctttctcaggtgcctttcctgtggcttttttggaaactcatttgaac aagcataatatctactcaatttacaataccaagaatgcaagagacagagcagttctcaat ttgcctgctagtgtagaagaggtctgcccaaatattccttccttggtgaagctaatggaa gaaatcgtggaactggcagagtctggtattcgttacacgcaaatgccacatatcatggaa gtaatactacctatgctatgtagttacatgtcacactggtgggagcatgggccggaaaac aatcccgacaaggctgaaatgtgttgcacagccttgacatcagagcatatgaacactctg ttgggtaacatattgaaaatcatctataacaaccttggtattgatgaaggagcctggatg aagagattagcagtgttttcccagcccatcataagcaaagcgaagccacagctcttaaag acacacttccttccactgatggataaactaaagaaaaaagcagcagtggttgtatcggat gaagaacatctaagagcagaaggcagaggtgacatgtcggaggctgaactgctcatccta gatgagttcaccactttggcacgggacctctatgccttctaccctttgttgattagattt gtggactataacagggcaaaatggctgaaagagcccaaccctgaagcagaagagttgttc cgcatggtggctgaggtcttcatttactggtcaaagtctcataatttcaaaagggaagag cagaactttgtggtacaaaatgaaatcaacaacatgtctttccttatcagtgacaccaaa tctaagatgtctaaggcagcagttactgaccaggagaggaagaagatgaagcggaaaggt gaccggtactctttgcagacctctctcattgtggcagcactgaagagattacttcccatc ggcctaaacatttgtgctcctggagaccaagagctaatttcactggccaaaaaccgattt agcatgaaagatactgaagatgaagtacgagatgtcatccgcagtaatcttcatcttcag ggcaagcttgaggatcccgccattaggtggcagatggcactttacaaagatttaccaaat agggctgaagattcctcagatccggagaagactgtggaaagggtccttgatatagctaat gtactgtttcacctggaacaggttgagcatcctcagaggtccaaaaaagcagtgtggcat aagctgctgtctaaacagaggaaaagagcagtagttgcctgctttagaatggcaccattg tataatttaccaaggcaccgagccgtcaatctctttcttcaaggctatgataaatcttgg attgaaacagaagaacactattttgaagacaaactgatagaagacttagcaaaacctggg gaggaaccaccagaggaagatgaaagccttaaaagagttgatcctttacatcagcttatt ctgctattcagtcgaacagccttgactgaaaaatgcaaattggaagaagattacctgtat atggcttacgctgacattatggcaaagagctgccatgatgaagaagatgatgatggtgaa gaagaagtgaagagttttgaagtgacaggatcacaacgcagcaaggaaaaagaaatggaa aaacaaaaacttctgtatcaacaagcaaggctgcatgatcggggtgctgctgagatggtt ctgcagacaatcagtgctagtaaaggtgagatggggccaatggttgcagctaccctaaag ctaggaattgccatcttaaatggaggaaattctactgttcaacagaaaatgcttgactac ctcaaggataaaaaggatgtgggattctttcagagccttgctggtcttatgcagtcctgt agtgttcttgacctaaatgcatttgaacgtcagaacaaagcagaagggcttggcatggtg actgaagagggatcaggagaaaaggtgatgcaggatgatgagttcatctgtgacctcttc cgcttccttcaattgctttgtgaaggacataattcagattttcagaattacctgagaact caaactggtaacaacacaactgtaaatattatcatttctactgtggactacttactgaga gttcaggaatccattagtgatttttattggtattattctgggaaggatgttattgatgag caaggacaaagaaatttttccaaagccatccaggttgcaaaacaagttttcaatactctt acagagtatatccaggggccttgtactgggaatcagcaaagtctggcacacagcaggctg tgggatgctgtagttggcttccttcatgtgtttgcccacatgcagatgaagctgtctcag gattccagtcaaattgaattactgaaggaattaatggatcttcagaaagatatggttgtc atgttgctgtctatgctggaaggtaatgttgtgaatggcactattggaaagcagatggtc gatatgcttgtggaatcgtcgaacaatgtagagatgattctgaagttttttgatatgttc ttaaaactgaaggatttaacttcctctgatgcattcaaagaatatgaccctgatggtaaa gggataatttcgaagagggattttcacagggcaatggaaagccacaaacattacacccag tctgaaactgagtttctgctgtcgtgtgctgaaacagatgagaatgagactctggactat gaggagtttgtgaaacgatttcatgaacctgccaaagacattggtttcaatgttgctgtt ctcttgaccaacctgtcagaacatatgccccatgatacccgcttgcaaacttttcttgaa ctctcagagagtgtgctaaattactttcagcctttccttggacgcatagaaatcatgggc agtgcaaagcgcattgaacgagtttattttgaaataagtgagtcaagtcggactcagtgg gagaaacctcaggtaaaagagtcaaagagacaatttatatttgatgttgtaaatgaaggt ggggagaaagaaaagatggagctttttgttaacttctgtgaggataccatctttgaaatg caactggctgcccagatctctgagtcagatctgaatgaaaggtcagcaaataaagaggag aatgagaaagataatcctgaggaagaagatcctagaatgggtttcttctctcttgtgacc atgaagtcagcattagtagctctcaagtataatttaatgactcttatgaaaatgcttagc atgaagagcctaaagaaacagatgaaaaaagtgaagaaaatgaccatgaaggacatggtc atggcattgttttcttcctattggagtattttgatgggcttgctacattttgcttatagt gttgtccggggcttctttcgcatcatatgcagtttgcttcttggaggaagcctagtagaa ggagcaaagaaaatcaaggtggctgaactactagctaatatgccagatcccactcaggat gaggtgcgtggggaaggtgaagaaggggagagaaaggcaacagaagctgcattgcctaca gaagacttgacagatctgcaaactttgtcagaagaaagtgatctactttcagatatattt ggtttggatttgaaacgagaaggtggacagtataaattgatccctcacaatccaaatgct ggtttgagtgatttactgagcactccctccttagctccaatgcctgaggtacaggaaaaa atccaggagcaggtgaaagaagatgaaaaggaagagaaagaggagacaaaatctgaacct gagaaagcagaaggagaagatggagaaaaagaagacaaaaacaaggatgacaaaggaaaa ctgaaattaagacaacttcatacgcacagacatggagaaccagaagttcaggaatcagtt ttctggaagaatatcattgcataccaacagaaacttcttaattattttgcacgaaacttt tacaacatgaggatgttggcgttatttgttgcttttgccatcaactttatcctgcttttc tataaggtctccacatctgctgtgacagaagaaaaggaacttcctgtggtatctgctggt gaaagtaccaagttgaacatcctggaaagtgatgatgacagggtcattgcagtgcattat gtccttgaagaaagcagtggctacatggaacccacactacgaattttggccatcctacac acagtcatctcattcttctgcatcatagggtattactgtttgaaagttccactggttata tttaagagagaaaaagaagtggcaaggaaattggaatttgatggattatatataactgaa cagccatcagaagatgatattaagggacagtgggatagacttgtaatcaacacacagtct tttccaaataactattgggacaaatttgtgaaaagaaaggtcatggataaatatggtgag ttctatggccgtgacaggatcagtgagttactaggaatggacaaagctgctcttgatttt agtgatgctcgagaaaagaagaaaccaaagaaggatagctccttttctgctgtgctaaat tccattgatgttaagtatcagatgtggaaattaggagttgttttcactgataattactct ggattatatttaatttactacatgagtgaactcttgggtgcttaa

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