Acidiferrobacter sp. SPIII_3: C4901_13925
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Entry
C4901_13925 CDS
T05469
Symbol
leuA
Name
(GenBank) 2-isopropylmalate synthase
KO
K01649
2-isopropylmalate synthase [EC:
2.3.3.13
]
Organism
acii
Acidiferrobacter sp. SPIII_3
Pathway
acii00290
Valine, leucine and isoleucine biosynthesis
acii00620
Pyruvate metabolism
acii01100
Metabolic pathways
acii01110
Biosynthesis of secondary metabolites
acii01210
2-Oxocarboxylic acid metabolism
acii01230
Biosynthesis of amino acids
Module
acii_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
acii00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
C4901_13925 (leuA)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
C4901_13925 (leuA)
Enzymes [BR:
acii01000
]
2. Transferases
2.3 Acyltransferases
2.3.3 Acyl groups converted into alkyl groups on transfer
2.3.3.13 2-isopropylmalate synthase
C4901_13925 (leuA)
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Motif
Pfam:
HMGL-like
IPMS_D2
LeuA_dimer
Nuc_deoxyri_tr2
Motif
Other DBs
NCBI-ProteinID:
AWP24289
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Position
complement(2759647..2761371)
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AA seq
574 aa
AA seq
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MMLETPHDKYRPFAPVNLTDRTWPGRTIETPPAWLSTDLRDGNQALFEPLNIDAKREFFE
LLCAVGFKEIEVGFPSASRADFTFVRDLIERRAVPDDVTIGVLTPARADLIDRSIEALAG
ARRAIVHLYNAVSPVFRDVVFRKTRAEVMAMAVDAARRIRAATDRRPETQWVLQYSPEAF
SATELDFAKAICDAVVEAFGATDEAPSIINLPATVEVATPNVFADQVEWMHRHIARREAV
ILSVHPHNDRGSAVAAAELAMMAGAERVEGCLFGNGERTGNVDLVTLALNLYTQGVAPRL
DFSRLDEIARTASRLTRLPVHPRHPYVGDLVYTAFSGSHQDAIHKGLSAQRPDDPWNVPY
LPLDPKDVGRDYQAVIRVTSQSGKGGVAHLLEACYGIVLPRRMLIGLGAAVQARADEGGG
EITAADIWNIFCDRYLKDPQAVRYHGHDLETGVDGDRVRLHLAIGGQTVRYEGYGNGPLD
AACRALPGAMRLCHYEERAVRAGSDAQALAIVEVAGLEDGRTVMAAGLHESLVTASLMAL
VRAWADLAAGAAIAGNGSHIALGGAAMAPQVGLP
NT seq
1725 nt
NT seq
+upstream
nt +downstream
nt
atgatgttggagacaccgcacgacaaataccggccctttgcgccggtgaatctcacggat
aggacgtggcccgggcgtacgattgagaccccgccggcctggctcagtaccgatctgcgc
gacgggaaccaggccctgttcgagcccctgaatatcgacgcgaagcgggaattcttcgaa
ctgctgtgcgcggtgggcttcaaggagatcgaggtcggtttcccgtcggcgtcgcgcgcc
gatttcaccttcgtgcgcgacctcatcgaacggcgtgcggtaccggacgatgtgaccata
ggggtgctcacgccggcacgcgccgatctcatcgaccgttcgatagaggcccttgcgggc
gcgcggcgggcgatcgtccacctctataacgccgtatcgccggtgtttcgcgacgtggtg
tttcgcaagaccagggccgaggtcatggccatggcggtcgatgccgcgcgccgcatacgg
gcggcaacggaccgccgtccggagacgcaatgggtcctgcagtacagcccggaggcgttc
agcgccacggaattggactttgcgaaggcgatctgcgatgccgtcgtggaggcgttcggc
gccacggatgaagccccctcgatcatcaatctgccggcaaccgtggaggtggcgacaccc
aatgtctttgccgatcaggtggaatggatgcaccgccacatcgcgcggcgcgaggcggtc
attttgagcgtgcatccgcataacgaccggggttccgccgtggcggccgcggagctcgcg
atgatggcgggcgcggaacgggtggaaggttgtctctttggcaacggcgagcgtaccggc
aacgtcgatctcgtgaccctcgcattgaacctgtatacgcaaggggtcgcgccacgactg
gatttttcgcgactcgacgagatcgcgcgcacggcctcgcgtctcacgcgtctgccggtg
catccgcgccacccttacgtcggggatctcgtgtacacggcgttttccgggtctcatcag
gacgcgatccacaaaggtctgtccgcgcagcgcccggatgacccctggaacgtgccctat
ctgccgctcgaccccaaggatgtggggcgcgactatcaggcggtgattcgcgtaaccagc
cagtcgggcaagggcggcgtcgcccacctcctggaggcctgctatgggatcgtgctgccg
cgccggatgttgatcggattgggcgcggcggtacaagcgcgcgccgatgaggggggaggc
gagatcacggcggccgatatctggaacatcttttgcgaccgttacctgaaggatccgcaa
gcggtccgctaccacggccatgatcttgagaccggcgtcgacggtgatcgggtgcgactg
caccttgccattggcgggcagaccgtgcgctacgaggggtacgggaacggtccgctggac
gcggcgtgccgggcattgccgggggcgatgcggttatgtcactacgaggagcgggcggtg
cgcgccgggtcggacgcgcaggccttggcgatcgtggaggtggcgggcctcgaggacggc
cggacggtgatggccgccggtctacacgagagtctcgtgacggcctcgctgatggccctg
gtccgggcgtgggccgatctggcggccggtgccgcgatcgctggcaatgggtcccatatc
gccctcgggggggctgcgatggcccctcaggtggggttgccatag
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