Actinomadura citrea: OG979_31405
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Entry
OG979_31405 CDS
T09741
Symbol
leuA
Name
(GenBank) 2-isopropylmalate synthase
KO
K01649
2-isopropylmalate synthase [EC:
2.3.3.13
]
Organism
acir
Actinomadura citrea
Pathway
acir00290
Valine, leucine and isoleucine biosynthesis
acir00620
Pyruvate metabolism
acir01100
Metabolic pathways
acir01110
Biosynthesis of secondary metabolites
acir01210
2-Oxocarboxylic acid metabolism
acir01230
Biosynthesis of amino acids
Module
acir_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
acir00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
OG979_31405 (leuA)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
OG979_31405 (leuA)
Enzymes [BR:
acir01000
]
2. Transferases
2.3 Acyltransferases
2.3.3 Acyl groups converted into alkyl groups on transfer
2.3.3.13 2-isopropylmalate synthase
OG979_31405 (leuA)
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GFIT
Motif
Pfam:
HMGL-like
IPMS_D2
LeuA_dimer
Motif
Other DBs
NCBI-ProteinID:
WUR56672
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Position
complement(6748503..6750179)
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AA seq
558 aa
AA seq
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MPFHRYRSAHERVPSPVPDVERTWPSGRIESAPLWVPVDLRDGNQALAEPMDTARKRRMF
DLLVTMGFKEIEVGYPSASRTDFDFVRHLAETGVPDDVTPVVFTPARGELIERTFASIEG
LPRAVVHLYTATGPVWRDVVLGAGRDGVRRLILDGAADVARLAGPGVRFEFSPETFNVTE
PDYALEVCDAVTALWDASPDRPVILNLPATVEIATPNVYADQIEYMHRNLARRDAVILSV
HPHNDRGTGVACAELAMLAGAQRVEGCLFGNGERTGNVDLVTLALNLHAQGVDPRIDFSD
IDEIRRTVEHCNRLPVHERHPYGGDLVYTAFSGTHQDAIGKGMARHARLAGERGVPPEGL
PWDVPYLPIDPADVGRGYEAVIRVNSQSGKGGISYLLRTGHGLDLPRRLQIEFSQVVQRA
TDGSGEEVTADELWELFRAEYLDRPGPVQVTGWRTSSTGPARHDFTGVVRVDGDEREHTG
TGNGPLDALTGALASAGIKVDVLQYAEHSAGAGRDAVAVAYAECRVDGATRWGAGRDTSV
LNASVEAVLSAVNRAKSG
NT seq
1677 nt
NT seq
+upstream
nt +downstream
nt
atgccgttccaccggtaccggtccgcccacgagcgcgtgccgtcgcccgtgccggacgtc
gagcgcacctggccgtccgggcgcatcgagagcgcgcccctgtgggtgcccgtcgacctg
cgggacggcaaccaggcgctggccgagcccatggacaccgcccgcaagcgccgcatgttc
gacctgctcgtcacgatgggcttcaaggagatcgaggtcggctatccctcggccagccgg
accgacttcgacttcgtccggcacctggccgagaccggcgtgccggacgacgtgacgccc
gtggtgttcacgcccgcgcgcggggagctgatcgagcggacgttcgcgtccatcgagggg
ctgcccagggccgtcgtccacctgtacacggcgacgggaccggtgtggcgggacgtcgtg
ctcggggccggccgggacggggtgcggcggctgatcctggacggcgcggccgacgtggcg
cggctcgccgggcccggcgtacggttcgagttctcccccgagacgttcaacgtcaccgag
cccgactacgccctggaggtatgcgacgcggtcaccgcgctgtgggacgcctcccccgac
cgcccggtgatcctgaacctgccggccacggtcgagatcgccactccgaacgtgtacgcc
gaccagatcgagtacatgcaccgcaacctggccaggcgcgacgcggtcatcctgtcggtc
cacccgcacaacgaccgcgggacgggcgtcgcgtgcgcggagctggcgatgctggccggc
gcgcagcgggtcgagggctgcctcttcggcaacggggagcggacgggcaacgtcgacctg
gtcacactggcgctgaacctgcacgcgcagggcgtcgacccgcggatcgacttctccgac
atcgacgagatccggcggacggtcgagcactgcaaccggctgcccgtccacgagcggcat
ccgtacggcggcgacctggtgtacacggcgttctccggcacccaccaggacgcgatcggc
aagggcatggcccgccacgcgcggctcgccggggagcggggcgtgccgccggaggggctg
ccgtgggacgtgccgtacctgccgatcgacccggccgacgtcgggcgcgggtacgaggcg
gtcatccgcgtcaacagccagtccgggaagggcggcatctcctacctgctgcgcacgggg
cacgggctcgacctgccgcgccgtctgcagatcgagttctcccaggtcgtgcagcgggcg
acggacggcagcggcgaggaggtcacggcggacgagctgtgggagctgttccgcgccgag
tacctcgaccggccgggaccggtccaggtgaccggatggcggacctccagcaccggcccg
gcgcggcacgacttcaccggcgtcgtccgggtcgacggcgacgagcgcgagcacaccggc
acgggcaacggcccgctggacgcgctgaccggcgcgctcgcgtccgccgggatcaaggtg
gacgtcctgcagtacgccgagcactcggccggggccgggcgggacgccgtggccgtcgcc
tacgccgaatgccgcgtggacggcgcgacccgctggggcgcgggacgcgacacgtccgtg
ctcaacgcgtcggtggaggccgtcctgtcggcggtcaatcgcgcgaagagcggctag
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