KEGG   Actinomadura citrea: OG979_31405
Entry
OG979_31405       CDS       T09741                                 
Symbol
leuA
Name
(GenBank) 2-isopropylmalate synthase
  KO
K01649  2-isopropylmalate synthase [EC:2.3.3.13]
Organism
acir  Actinomadura citrea
Pathway
acir00290  Valine, leucine and isoleucine biosynthesis
acir00620  Pyruvate metabolism
acir01100  Metabolic pathways
acir01110  Biosynthesis of secondary metabolites
acir01210  2-Oxocarboxylic acid metabolism
acir01230  Biosynthesis of amino acids
Module
acir_M00432  Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:acir00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00620 Pyruvate metabolism
    OG979_31405 (leuA)
  09105 Amino acid metabolism
   00290 Valine, leucine and isoleucine biosynthesis
    OG979_31405 (leuA)
Enzymes [BR:acir01000]
 2. Transferases
  2.3  Acyltransferases
   2.3.3  Acyl groups converted into alkyl groups on transfer
    2.3.3.13  2-isopropylmalate synthase
     OG979_31405 (leuA)
SSDB
Motif
Pfam: HMGL-like IPMS_D2 LeuA_dimer
Other DBs
NCBI-ProteinID: WUR56672
LinkDB
Position
complement(6748503..6750179)
AA seq 558 aa
MPFHRYRSAHERVPSPVPDVERTWPSGRIESAPLWVPVDLRDGNQALAEPMDTARKRRMF
DLLVTMGFKEIEVGYPSASRTDFDFVRHLAETGVPDDVTPVVFTPARGELIERTFASIEG
LPRAVVHLYTATGPVWRDVVLGAGRDGVRRLILDGAADVARLAGPGVRFEFSPETFNVTE
PDYALEVCDAVTALWDASPDRPVILNLPATVEIATPNVYADQIEYMHRNLARRDAVILSV
HPHNDRGTGVACAELAMLAGAQRVEGCLFGNGERTGNVDLVTLALNLHAQGVDPRIDFSD
IDEIRRTVEHCNRLPVHERHPYGGDLVYTAFSGTHQDAIGKGMARHARLAGERGVPPEGL
PWDVPYLPIDPADVGRGYEAVIRVNSQSGKGGISYLLRTGHGLDLPRRLQIEFSQVVQRA
TDGSGEEVTADELWELFRAEYLDRPGPVQVTGWRTSSTGPARHDFTGVVRVDGDEREHTG
TGNGPLDALTGALASAGIKVDVLQYAEHSAGAGRDAVAVAYAECRVDGATRWGAGRDTSV
LNASVEAVLSAVNRAKSG
NT seq 1677 nt   +upstreamnt  +downstreamnt
atgccgttccaccggtaccggtccgcccacgagcgcgtgccgtcgcccgtgccggacgtc
gagcgcacctggccgtccgggcgcatcgagagcgcgcccctgtgggtgcccgtcgacctg
cgggacggcaaccaggcgctggccgagcccatggacaccgcccgcaagcgccgcatgttc
gacctgctcgtcacgatgggcttcaaggagatcgaggtcggctatccctcggccagccgg
accgacttcgacttcgtccggcacctggccgagaccggcgtgccggacgacgtgacgccc
gtggtgttcacgcccgcgcgcggggagctgatcgagcggacgttcgcgtccatcgagggg
ctgcccagggccgtcgtccacctgtacacggcgacgggaccggtgtggcgggacgtcgtg
ctcggggccggccgggacggggtgcggcggctgatcctggacggcgcggccgacgtggcg
cggctcgccgggcccggcgtacggttcgagttctcccccgagacgttcaacgtcaccgag
cccgactacgccctggaggtatgcgacgcggtcaccgcgctgtgggacgcctcccccgac
cgcccggtgatcctgaacctgccggccacggtcgagatcgccactccgaacgtgtacgcc
gaccagatcgagtacatgcaccgcaacctggccaggcgcgacgcggtcatcctgtcggtc
cacccgcacaacgaccgcgggacgggcgtcgcgtgcgcggagctggcgatgctggccggc
gcgcagcgggtcgagggctgcctcttcggcaacggggagcggacgggcaacgtcgacctg
gtcacactggcgctgaacctgcacgcgcagggcgtcgacccgcggatcgacttctccgac
atcgacgagatccggcggacggtcgagcactgcaaccggctgcccgtccacgagcggcat
ccgtacggcggcgacctggtgtacacggcgttctccggcacccaccaggacgcgatcggc
aagggcatggcccgccacgcgcggctcgccggggagcggggcgtgccgccggaggggctg
ccgtgggacgtgccgtacctgccgatcgacccggccgacgtcgggcgcgggtacgaggcg
gtcatccgcgtcaacagccagtccgggaagggcggcatctcctacctgctgcgcacgggg
cacgggctcgacctgccgcgccgtctgcagatcgagttctcccaggtcgtgcagcgggcg
acggacggcagcggcgaggaggtcacggcggacgagctgtgggagctgttccgcgccgag
tacctcgaccggccgggaccggtccaggtgaccggatggcggacctccagcaccggcccg
gcgcggcacgacttcaccggcgtcgtccgggtcgacggcgacgagcgcgagcacaccggc
acgggcaacggcccgctggacgcgctgaccggcgcgctcgcgtccgccgggatcaaggtg
gacgtcctgcagtacgccgagcactcggccggggccgggcgggacgccgtggccgtcgcc
tacgccgaatgccgcgtggacggcgcgacccgctggggcgcgggacgcgacacgtccgtg
ctcaacgcgtcggtggaggccgtcctgtcggcggtcaatcgcgcgaagagcggctag

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