Arcobacter cloacae: ACLO_0570
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Entry
ACLO_0570 CDS
T06845
Symbol
leuA
Name
(GenBank) 2-isopropylmalate synthase, bacterial type
KO
K01649
2-isopropylmalate synthase [EC:
2.3.3.13
]
Organism
aclo
Arcobacter cloacae
Pathway
aclo00290
Valine, leucine and isoleucine biosynthesis
aclo00620
Pyruvate metabolism
aclo01100
Metabolic pathways
aclo01110
Biosynthesis of secondary metabolites
aclo01210
2-Oxocarboxylic acid metabolism
aclo01230
Biosynthesis of amino acids
Module
aclo_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
aclo00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
ACLO_0570 (leuA)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
ACLO_0570 (leuA)
Enzymes [BR:
aclo01000
]
2. Transferases
2.3 Acyltransferases
2.3.3 Acyl groups converted into alkyl groups on transfer
2.3.3.13 2-isopropylmalate synthase
ACLO_0570 (leuA)
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Gene cluster
GFIT
Motif
Pfam:
HMGL-like
HCS_D2
LeuA_dimer
IPMS_D2
NADH_4Fe-4S
Motif
Other DBs
NCBI-ProteinID:
QKF89095
LinkDB
All DBs
Position
572147..573700
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AA seq
517 aa
AA seq
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MDKNKIIVFDTTLRDGEQSPGCSMNTEEKIKVALQLEKLGVDVIEAGFAAASPGDFDAVS
RIAEIVKNSSICSLSRAVENDIKQSGLAVSKAPKHRIHTFIATSPIHMKYKLKMTPDEVI
KRAIHAVEYAKTFVDDVEFSLEDAGRSEISFMKEVMDAVIEAGARTINLPDTVGYRLPTE
LGAMVKELSAYAGDRAIISVHNHNDLGLATANTLAAVLNGARQIEVTINGLGERAGNSAL
EEAVMAIKTRKDAFGDLYTTINTPEIYATSRLVATITGVEPQQNKAIVGKNAFAHESGIH
QDGVLKHQETYEIMKPEDVGVFKDSTLILGKHSGRAAFRDKIVHLGFDKVTDEELNAAFE
RFKVLADKKKEVTDDDIRMLITDESLNHDKTYELIGLQISDCTAGVPTAAVAIKYKDEIL
RDAAIGDGTMDAIFKTIDRLTGYNGELKDYKVISVTEGKDALAKVTTRVSFDETSPAFVG
HGLSIDTMLATAKAYLGALNSYLSQKERLSKSCEHQV
NT seq
1554 nt
NT seq
+upstream
nt +downstream
nt
atggataaaaataaaattatagtatttgatacaacattaagagatggtgaacaaagtcct
ggttgttctatgaacacagaagaaaaaataaaagtggcattacagttagaaaaattagga
gttgatgtaattgaagctggttttgcagctgcaagtccaggagatttcgatgctgttagt
agaattgctgaaattgttaaaaattcaagtatctgttctttgagtagagctgttgagaat
gatattaaacaatcaggtttagcagttagtaaagctcctaaacatagaattcatacattt
atagcaacttcaccaattcatatgaaatacaaattgaaaatgactccagatgaagtaatc
aaaagagcaattcatgcagttgagtacgcaaaaacatttgttgatgatgttgagttctct
ttagaagatgcaggaagaagtgaaatttcatttatgaaagaagtaatggatgctgtaata
gaagcaggggctagaactataaatttaccagatacagtaggatatagattaccaacagaa
ttaggtgcaatggttaaagaattaagtgcttatgcaggtgatagagcgattatttcagtt
cataatcacaatgatttaggattagcaacagcaaatactttagcagctgttttaaatggt
gctagacaaattgaagtaacaataaatggtttaggagaaagagctggaaattcagcttta
gaagaggctgttatggctattaagacgcgaaaagatgcttttggagatttatatacaaca
attaatactcctgaaatttatgcaacttcaagattagtagcaacaattacaggtgttgag
ccacaacaaaataaagcaattgttggtaaaaatgcatttgcacatgaaagtggaattcac
caagatggtgttttaaaacatcaagaaacttatgaaattatgaaacctgaagatgttgga
gtatttaaagactctactttaattttaggtaaacatagtggtcgtgcagcatttagagat
aaaattgttcatttaggttttgataaagtaacagatgaagagttaaatgcagcatttgaa
agatttaaagttttagctgataagaaaaaagaagtaacagatgatgatattagaatgtta
ataactgatgaatctttaaatcatgataaaacttatgagttaataggattacaaattagt
gattgtacagcaggtgttccaacagcagctgttgctattaaatataaagatgagatttta
agagatgcagctattggtgatggaacgatggatgctatatttaaaacaattgatagatta
acaggttataatggcgaattaaaagattataaagtaatctctgtaactgaaggaaaagat
gctttagcaaaagttacaacaagagtatcttttgatgaaacaagtcctgcttttgtagga
catggattaagtattgatacaatgcttgcaactgcaaaagcatatttaggagctttaaat
tcttatctttctcaaaaagagagactttctaaaagttgtgagcatcaagtataa
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