Aphelocoma coerulescens (scrub jay): 138113828
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Entry
138113828 CDS
T10543
Symbol
DPYD
Name
(RefSeq) dihydropyrimidine dehydrogenase [NADP(+)] isoform X1
KO
K00207
dihydropyrimidine dehydrogenase (NADP+) [EC:
1.3.1.2
]
Organism
acoe Aphelocoma coerulescens (scrub jay)
Pathway
acoe00240
Pyrimidine metabolism
acoe00410
beta-Alanine metabolism
acoe00770
Pantothenate and CoA biosynthesis
acoe00983
Drug metabolism - other enzymes
acoe01100
Metabolic pathways
Module
acoe_M00046
Pyrimidine degradation, uracil => beta-alanine, thymine => 3-aminoisobutanoate
Brite
Enzymes [BR:
acoe01000
]
1. Oxidoreductases
1.3 Acting on the CH-CH group of donors
1.3.1 With NAD+ or NADP+ as acceptor
1.3.1.2 dihydropyrimidine dehydrogenase (NADP+)
138113828 (DPYD)
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Other DBs
NCBI-GeneID:
138113828
NCBI-ProteinID:
XP_068878740
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Position
8:14677792..15044334
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AA seq
1025 aa
AA seq
DB search
MARVLSRDPVDIENILALNPRKQTHATLHSTAAKKQVKKQWKRNSDKNCSNCEKLENNFD
DIKHTTLSERGALREAMRCLKCADAPCQKSCPTNLDIKSFITSIANKNYYGAAKMILSDN
PLGLTCGMVCPTSDLCVGGCNLYATEEGPINIGGLQQFATEVFKAMNIPQIRNPSLPPPE
DMPEAYQAKIALLGAGPASLSCATFLARLGYSDITIFEKQEYLGGLSMSEIPQFRLPYDV
VNFEAELMKDLGVKIIFRKGLAVDGMTLHTLKEDGYKAVFIGIGLPEPNRDRIFQGLRMN
QGFYTSKDFLPLVAMASKPGMCACHSPLPSIHGTVIVLGAGDTAFDCATSALRCGARRVF
VVFRKGFTHIRAVPEEMELAKEEKCEFLPFLSPRKVVLKGGQIVAMEFVRTEQDSDGNWR
EDEDQVVRLKADVVISAFGSILSDNKVREALAPIKFNRWGLPEVDPETMQTSEPWVFAGG
DVGGVANTTVESVNDGKQASWYMHRYIQSLYGVAVSTVPELPLFYTPIDLVDISVEMAGL
KFPNPFGLASATPATSSSMIRRAFEAGWGFAVTKTFSLDKDIVTNVSPRIVRGTTSGPLY
GPGQGSFLNIELISEKTAAYWCKSITELKADFPNHVLIASIMCSYNREDWTELSKMAEVA
GADALELNLSCPHGMGERGMGLACGQDPELVRNICRWVRQAVHIPFFAKLTPNVTDIVKI
GVAAQEGGADGVTATNTVSGLMGLKADSTPWPAVGRGLRTTYGGMSGNAIRPIALRAVSA
IARALPGFPILATGGIDSAEAGLQFLHSGASVLQVCSAIQNQDFTVIDDYCTGLRALLYL
KSIEELEDWDGQSPATMCHQKGKPVPRIADLMGKKLPSFGPYLEQRKKIIAENKIKLKAQ
NMAAVLPEKKHFVPKKPIPAIKDVIGKALQYIGTYGDLCNTEQVVALIDEEMCINCGKCY
MTCNDSGYQAIQFDPETHLPTVTDSCTGCTLCLSVCPVIDCIRMVSRTTPYEPKRGLPLA
VNPAH
NT seq
3078 nt
NT seq
+upstream
nt +downstream
nt
atggctcgtgtgctgagccgggacccggtggacattgagaacattctggctttaaatccc
cgaaaacaaacacatgcaactcttcactcaactgcagcaaagaaacaagtcaagaagcaa
tggaaaaggaattctgacaaaaactgttcaaactgtgagaaactggaaaataattttgat
gacatcaagcacacgactcttagtgagcgaggagcacttcgagaagcaatgagatgctta
aagtgtgcagatgccccctgtcagaagagttgcccaactaatctggacatcaagtcattc
atcacaagcattgcaaacaagaactattacggagctgccaaaatgattctttctgacaat
ccacttggcctgacatgtggaatggtgtgtccaacatcagatctctgtgttggtggctgc
aatttgtatgccactgaggaaggaccaattaatatcggtggattgcagcagtttgctact
gaggttttcaaagccatgaatattcctcagatcagaaacccttccttacctcctccagaa
gatatgcctgaagcatatcaggcgaagatagctcttcttggtgcgggacctgcgagctta
agttgtgctacctttttggctcgattgggctattcagacatcaccatatttgaaaagcag
gagtaccttgggggcttaagtatgtctgaaatcccccagttccgattgccatatgatgta
gtgaattttgaagccgagcttatgaaggatcttggagtgaagatcatttttaggaaaggc
cttgcagtggatggaatgacactccataccctgaaggaagatggctataaagcagtcttt
attggaataggtttgccagaaccaaacagagaccgtatattccaaggactgagaatgaat
caaggattctacacatctaaagacttcttacctctggtagcaatggcaagtaaaccaggg
atgtgtgcctgtcactctccgttgccatcaatacatggaactgtgattgtactcggggca
ggagacactgcttttgactgtgcaacatctgctctgcgctgcggagctcgtcgcgtgttt
gtggtcttcaggaagggattcactcatatcagggctgtcccagaagagatggaacttgca
aaagaagagaagtgtgaatttctgcctttcctctctcctcggaaagttgttcttaaaggt
ggacaaattgttgctatggaatttgttcgaactgaacaagacagtgatggaaactggaga
gaagatgaggatcaggttgtccgtctgaaagccgatgtggtgatcagtgcctttggctcc
attttaagtgacaataaagtcagagaggccctggcacctatcaagtttaacagatggggt
ctccctgaagtagacccagaaactatgcaaacgagtgaaccctgggtgtttgcagggggt
gacgttggtggtgttgctaacactacagtggaatccgtaaacgatggaaaacaagcttcc
tggtacatgcacagatacatacagtccttatatggtgttgcagtttctacggttccagaa
ctcccactcttctatactcctatcgatttagtggatatcagtgtagaaatggctggactg
aagtttccaaatccttttggccttgccagtgcaacccctgctacgagttcttcaatgatt
cgaagagcatttgaagctggatggggctttgctgtcactaaaacgttctccctggataag
gatattgtgaccaatgtttctccaaggattgtgcgtggaactacttcaggtcctctgtat
ggcccaggccaaggctctttcctaaacattgaactgatcagcgagaaaacagcagcatat
tggtgtaaaagcattactgaactgaaggctgactttccaaaccacgttctgattgccagc
atcatgtgcagctataacagggaggactggactgaactttcaaaaatggctgaggttgct
ggtgctgatgcgctggagttaaatttatcatgtcctcatggtatgggggagcgaggcatg
ggactggcctgtgggcaggatccagagctggtacggaacatctgtcgctgggttagacaa
gctgttcacattcctttctttgccaaactgaccccaaatgtcactgatattgtgaaaatt
ggagtggctgcgcaggaaggtggcgcagatggggttacagccaccaacactgtgtcagga
ctgatgggactgaaagcagacagcacaccttggccagcagttggtcgaggactgaggacc
acatatggtggcatgtcaggaaatgctatccggcccatcgccctccgcgcagtgtctgcc
atcgcccgtgccctcccaggatttcccatcttggcaactggaggcatcgattctgctgag
gctgggcttcagtttctgcacagtggggcttctgtcttacaggtgtgcagtgcgatccaa
aatcaagatttcactgttattgatgactactgcactggactacgagctcttctttacctg
aaaagcattgaggaacttgaagactgggatggacagagtcctgcaaccatgtgccatcag
aaaggaaaaccagtaccgagaattgccgatctgatgggaaagaaactgcccagttttgga
ccttacctggagcaacgcaaaaagataatagctgagaacaagattaaactgaaggcacag
aacatggctgctgtgcttcccgagaaaaagcactttgttccaaagaagcccattccagca
atcaaggatgtaattggaaaagcactgcagtatattggaacatatggtgatctgtgcaac
acagagcaagttgtggctctgattgacgaggaaatgtgtatcaactgtggcaaatgctac
atgacctgtaatgattctggctaccaggctatccagtttgatcccgaaacccacctgccc
acggttactgacagctgtacaggctgcaccctgtgtctcagcgtgtgccctgtgatcgac
tgcatccgcatggtttccaggacaaccccctacgagcccaagcgcgggctgcccttagcc
gtgaaccccgcgcactga
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