Candidatus Accumulibacter cognatus: HWD57_01090
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Entry
HWD57_01090 CDS
T10916
Symbol
folC
Name
(GenBank) bifunctional tetrahydrofolate synthase/dihydrofolate synthase
KO
K11754
dihydrofolate synthase / folylpolyglutamate synthase [EC:
6.3.2.12
6.3.2.17
]
Organism
acog Candidatus Accumulibacter cognatus
Pathway
acog00790
Folate biosynthesis
acog01100
Metabolic pathways
acog01240
Biosynthesis of cofactors
Module
acog_M00126
Tetrahydrofolate biosynthesis, GTP => THF
Brite
KEGG Orthology (KO) [BR:
acog00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
HWD57_01090 (folC)
Enzymes [BR:
acog01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.12 dihydrofolate synthase
HWD57_01090 (folC)
6.3.2.17 tetrahydrofolate synthase
HWD57_01090 (folC)
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Motif
Pfam:
Mur_ligase_C
Mur_ligase_M
Motif
Other DBs
NCBI-ProteinID:
QLH48541
UniProt:
A0A7D5SJ12
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All DBs
Position
complement(253006..254325)
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AA seq
439 aa
AA seq
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MSKGEGRASAIPEHTLERWLAQLESLHPRGQAGIELGLERVQRVKRELGRHPQCPLVTVG
GTNGKGSTCAYLEAIYHFAGYRVGCYTSPHLLKYNERVRVDRIPVDDVGLCEAFARVEAA
RQAAGDVALTYFEFGTLAAIEVFRVREVEVMILEVGLGGRLDAVNAYDPDCAVVTSVALD
HTDWLGSTREAIGFEKAGIFRASRPAVCADPEPPQSLLSHAQAIGADLYLLGRDFGHFGE
RLQWTFWRNGGRRRSGLANPGLRGACQLRNASAALFVVDLLGQRLPVSMQAIRSGLIEPD
LPGRFQVLPGRPAIVLDVAHNPQAVGVLADNLGDMAFSSRTIAVVGMLADKDIAGSLAPL
AGKVDTWLLADLDVPRGASAVVLAAAVSSAGLGGRVECFASPRQAFARSAELAEENGRII
VFGSFYTVAAVMHSMQHGR
NT seq
1320 nt
NT seq
+upstream
nt +downstream
nt
gtgagcaaaggggaaggcagggcatcggcgatccctgagcacacgctggaacgctggctg
gcgcagctcgaaagcctccacccgcgcgggcaggcgggaatcgagttggggctggaacga
gtccagcgcgtcaagcgggaattgggccggcatccgcaatgtccactggtcaccgtcggc
ggcaccaacggcaagggttcgacctgcgcctaccttgaagcgatctaccatttcgccggt
taccgcgtgggttgctacacttcgccgcatctgctgaagtacaacgagcgggtgcgtgtt
gatcggatcccggtagacgacgtcgggctatgtgaggcctttgcccgcgttgaggcggcg
cgacaggccgctggcgatgtcgcactgacgtatttcgagtttggtactttggccgccatc
gaggttttccgtgtccgcgaggtcgaagtgatgattctcgaagttgggctgggtggccgc
ctcgatgcagtcaatgcctatgatcccgattgcgccgtggtgaccagtgtcgcgctcgat
cataccgactggctcggttcgacacgcgaggccattggtttcgagaaggccggcatcttt
cgtgcgagcagaccggcagtatgcgcggatccggaaccgccgcaatcgctgctgtcacat
gcgcaggccattggcgccgacctgtacctgctgggtcgtgatttcggtcatttcggtgag
cggttgcaatggaccttctggcggaatggtggccggcgccggagtggcctcgcgaatcct
ggtttgcgcggcgcctgccagctgcgcaatgcctcggccgctcttttcgtcgtcgacctg
cttggacagcgcttaccggtttcgatgcaggcgatccggagcgggctgatcgaaccggat
ttgccggggcgtttccaggtgttgccgggtcgtccggcgattgtcctcgatgtggcacac
aatccccaggcggtgggcgtcctggcagacaacctgggcgacatggctttctccagcagg
acgattgccgttgtcggaatgcttgccgacaaggacatcgccggttcgctggcgcccttg
gccggcaaggtggatacctggctactggccgacctcgatgtgccacgtggcgcatcggcg
gtcgtcctggctgcggccgtcagcagcgccggcctcggcggtcgtgtcgagtgttttgcc
tcaccgcggcaagccttcgcgcgttctgcagagttggccgaggaaaatggtagaatcatc
gtttttggatcgttctacacggtcgcggccgtcatgcacagcatgcaacatggtcgctga
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