Anopheles coluzzii: 120958269 Help Entry 120958269         CDS       T07312                                  Name (RefSeq) ryanodine receptor isoform X1   KO K04962   ryanodine receptor 2 Organism acoz  Anopheles coluzzii Brite KEGG Orthology (KO) [BR:acoz00001]  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04040 Ion channels [BR:acoz04040]     120958269    04990 Domain-containing proteins not elsewhere classified [BR:acoz04990]     120958269 Ion channels [BR:acoz04040]  Voltage-gated cation channels   Ryanodine receptor    120958269 Domain-containing proteins not elsewhere classified [BR:acoz04990]  EF-hand domain-containing proteins   Other EF-hand domain-containing proteins    120958269 BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  RYDR_Jsol RYDR_ITPR RyR Ins145_P3_rec SPRY MIR RR_TM4-6 RIH_assoc Ion_trans EF-hand_7 TPR_TTI1_C GET2 Motif Other DBs NCBI-GeneID:  120958269 NCBI-ProteinID:  XP_040236876 LinkDB All DBs Position 3:68829355..68870104 Genome browser AA seq 5113 aa AA seqDB search MAEAEGGSEQDDVSFLRTEDMVCLSCTATGERVCLAAEGFGNRHCFLENIADKNIPPDLS QCVFVIEQALSVRALQELVTAAGSETGNDSVGKGTGSGHRTLLYGNAILLRHNNSDMYLA CLSTSSSNDKLSFDVGLQEHSQGEACWWTVHPASKQRSEGEKVRVGDDLILVSVATERYL HTTKENDLSIVNASFHVTHWSVQPYGTGISRMKYVGYVFGGDVLRFFHGGDECLTIPSTW SLDSGQNIVVYEGGSVMSQARSLWRLELARTKWAGGFINWSHPMRIRHLTTGRYLGVNEN NELILMSRDQATTSQTAFVLRLEKDDQKVVLEDKDLEIIGAPIIKYGDSTVIMQHYESGL WVSYKSYETKKKGVGKVEEKQAILHEEGKMDDGLDFSRSQEEESRTARVIRKCSSLFTKF ISGLETLQENRRHSIFLQTVNLGEMVMCLEDLINYFAQPEDDMEHEEKQNRLRALRNRQD LFQEEGVLNLILEAIDKINVISSQGFLASFLASDESGQSWDMISGYLYQLLAAIIKGNHT NCAQFANSNRLNWLFSRLGSQASSEGSGMLDVLHCVLIDSPEALNMMRDEHIKVIISLLE KHGRDPKVLDVLCSLCVGNGVAVRSSQNNICDFLLPGKNLLLQTGLVDHVASIRPNIFVG RVEGSAIYQKWYFEVTMDHIEQMTHMTPHLRIGWANTAGYVPYPGGGEKWGGNGVGDDLF SYGFDGVYFWSAGRRTCVVPREVTEPFIKKGDVIGCTLDLSVPVIRFTFNGEPVQGCFTD FNLDGMFFPVMSCSSKLSCRFLFGGDNGRLKFNPPPGFSPLVQCLMPHQNLSLDPCFYFG NLNKNVLAGPWLVEDDSAFVPKPVDTSIVTLPSSVETIKDKLAENIHEMWALNKIEAGWT WGERRDDVYRIHPCLTSFEKLPAAEKRYDCQLAVQTLKTILALGYYISMDKPPARIRPIR LPNDPYMQGNGYKPAPLDLSAAVLTPKMEELVDQLAENTHNLWAKERIQQGWTYGLNEDS ENLRSPHLVPYSKVDEAIKKANRDTASETVRTLLIYGYNLDPPTGEANEALAAEALRQKF AAYRTYRVERTYAVTSGKWYFEFEVLTAGPMRVGWARADCNPGTMLGSDDASWAFDGYNA RKMHLHTVEDFGKRYKIGDIIGCFINVHEKSMSFSLNGELLMDALGGETTFADVNAPDGV GFVPACTIGIGQKARVVYGQDVDSLKWFTTCGLQEGYEPFCVNMKRPVTHWYTKDQPIFE NTDEIPECKIDVTRIPGGADTPPCMKISHNTFETMEKANWEFLRLSLPVTCANTFITEQE KMRRWEEIRIRQHRLMTEVDHSAPAHFDHIMRSGFTMNDIKGLHRNYSEDAAEADEMMRN GPRRPSRHQGRGGLSPPGIEINGEATSDGELNAYSDNELEGGDDRKKRGRSPFRLFGKKR DQSKDKLKDRRTPEPEPRKSNLKVTQRGQATRMSNSDLRAQAPLTPERKGMGSPQVESFG NEVYDADCLRLINEYFYGVRIFPGQDPTHVYVGWVTTQYHVHSKEFSQNKVRHAAIYVED ENEKTIEIVNRQSCYMVRADELFNEVTQDSSGKGASQGMFVGCFVDTATGTIRFTCEGKE TSHVFLMEPDTKLFPAIFVEATSKEILQIELGRTPTTLPLSAAVLPTSDKHINPQFPPRL KVQCLKPHQWARVPNTALQVHALKLSDIRGWSMLCEDPVSMLALHIPEEDRCIDILELIE IDRLLQFHAHTLTLYSALCYQSNYRAAHALCSHVDQKQLLYAIQSEYMSGPLRLGFYDLL ISLHLESHATTMEVCKNEYIIPLGSELRELYIDPEMCHSLRSLQTLSVRPEMNMTEIAPT PSQSNMPTIVAPDSSSEPIPAIDSLYSPRFPLEVVREFVMSALQEAVQINQVHNRDPIGG SNENLFLPLIKLIDRLLLVGVITNEDVEKLLIMIDPETWDPSFEKEGRDEHRKGLLTMKM AEGAKLQMCYLLHHLYDVQLRHRVESIIAFAHNYVGDLQQDQLRRYIEIKQSDLPSAVAA KKTREFRCPPREQMNAILGYKNLEEDDLENASCGPELRNRLIEFHEKLMGKVSLNALQEP EEPEADKLEEGRPGALKKLYNFINAVKELEEDPKEPVEEEKKTPEEVFRKVLIKQLVSWA EESQIENPKLVREMFGLLVRQYDTIGELIKALNKTYVINSKTKGDVANMWIGLSQIRALL PVQMSQEEEELMRKRLWKLVNNHTFFQHPDLIRILRVHENVMAVMMNTLGRRAQAQSDAP VQTADGEESAPKEKDTSHQMVVACCRFLCYFCRTGRMNQKAMFDHFDFLLENSNILLSRP SLRGSTPLDVAYSSLMENTELALALREHYLEKIAIYLSRCGLQSNSELIERGYPDLGWDP VEGERYLDFLRFCVWVNGESVEENANLVIRLLIRRPECLGPALRGEGEGLLKAIVDANKM SERISERRKMQDEAEGTITGLNFSHPLPEGDDDEDYIDTGAAILCFYCTLVDLLGRCAPD AAVIEQGKNESLRARAILRSLVPLEDLQGVLSLKFTLTNPALGEDRPKSDMPSGLVPGHK QSIVLFLERVYGIETQELFYRLLEDAFLPDLRAATMLDRSDGSESDMALSMNRYIGNSIL PLLIKHSKFYNEAENYASLLDATLHTVYRMSKNRMLTKGQREAVSDFLVALTSAMHPAML LKLLRKLTIDVSKLSEYTTVALRLLTLHYERCAKYYGTTGGGQASQFGASSDEEKRLTML LFSNIFDSLSNMDYDPELFGKALPCLIAIGCALPPDYSLSKNSDDDLYGKPTGGGPDQPH YNPQPIDTTAVQLTNDLNQIVQKFSEHYHDAWASRKLENGWTYGDQWSDANKTHPRLKPY NTLSEYERERYREPVRESLKALLALHWRIEHSEGDVPLSNRGSMRRQSKPNLELQGDTGS PFNYNPHPVDMTNLTLSREMQNMAERLAENSHDIWAKKKNEELDQCGGAIHAQLVPYDLL TDKEKRKDRERSQEFLKYLQYQGLKLHKPSRGQTEEPGMSTAAIELRFAYSLLEKLISYS DRATINMKLLKPSSTFSRRSSFKTCSRDIKFFSKVVLPLMEKYFSSNRNYFIAIATATNN VGAASLKEKEMVAGLFCKLASLLRHRLAAFGADVRITVRCLQVLVKSIDAKSLVKNCPEF IRTSMLTFFNNTADDLGQTIVNLTDGKYDRLRGTHLKTSTSLAYVNQVILPVLTSLFDHL AACDYGSDLLLDEIQVASYKILSALYTLGTDTSLTRDRKYLKTELERHKPALGSCLGAFS SCFPVAFLEPHANKHNPFSLLNRIADTSLEAQDIMSKMECCMPTLESILSEVDQFVESEK TYQEAQHIIDVILPLLCSYLPFWWNQGPDNVSPQSGNHVTMVTADHMNHLLKNVLKMIRK NIANENAPWMTRIATYTQQIIINSSEELLKDVFLPLAERVKKRCDSMFHKEESLRGFLKS STDDTSQIEAQIQEDWQLLVRDIYSFYPLLIKYVDLQRNHWLKDNVAEAEELYNYVAEIF NVWSKSQYFLKEEQNFISANEIDNMTLIMPTATRRSAAVSGDMPASGGKVKKKKRSRDKK RDKDKEIQSSLMVACLKRLLPVGLNLFAGKEQELVQHCKDRYLKKMPEYEVIEFARTQLT LPDKLDPADEMSWQHYLYSKLGKKEQIVQDTLEKSDKKPENKIEDTVERIVAMAKVLYGL HMACRPRAKGLNWTHVLSQARRKMAVACLRAKPMYRLSRHRACNIFARSYSELWLEDENT GQEVMIEDLTQTFEDAEKKKKDEEEEEGKPDPLTQLVTTFCRGAMTERSGALQEDPLYMS YASIVARSCGEEEEEGGDEEEGAGEDEGGASIHEQEMEKQKLLFHQARLANRGVAEMVLL HISASKGVPSEMVMRTLELGIAVLRGGNIDIQMGMLNHLKEKKDVGFFTSIAGLMNSCSV LDLDAFERNTKAEGLGVGSDGAAGEKNMHDAEFTCALFRFIQLTCEGHNLDWQNYLRTQA GNTTTVNVVICTVDYLLRLQESIMDFYWHYSSKELIDPAGKANFFKAIGVASQVFNTLTE VIQGPCTQNQQALAHSRLWDAVGGFLFLFSHMQDKLSKHSSQVDLLKELLNLQKDMITMM LSMLEGNVVNGTIGKQMVDTLVESASNVELILKYFDMFLKLKDLTSTPSFMEIDSNGDGW IMPKDFREKMEQQKSYTPEEIDFLLACCETNHDGKIDYIGFVDRFHEPAKEIGFNLAVLL TNLSEHMPNEPRLARFLETAGSVLNYFESFLGRIEIMGSSKRIERVYFEIKEANIEQWEK PQIKESKRAFFYSIVTEGGDKEKLEAFVNFCEDAIFEMTHASGLMASDDDGGTVRRDQAF TYISEEEEERAARDPIKRTIQAVKDGLSYSMYMISPSNIKHQITVLQSKSFPEIIVGFFK MIFYAFYYSGFGVSVVIKYLVNILMSLMRGPAQEEEEPIPEAEPSLRALPPLPLEEPPGT VQAFGLDISKEENGQYRMAPHESPALSPSSSIEETGESSPEDGAAELTGEGVPPGEQMTL VDLLGGEAAKRAAQERTEAQKAQEATLASIEAESKKASTETKEPAAVHQIDFSKYTKKCV SYLARNFYNLKYVALVLAFCINFMLLFYKVTTLGDDEDGEGGSGESLMGLGSGLGSGLGI LETGSGGGEGGSGDGEGEEEDPPEKVHVDEDFFYMEHVLRIAAILHSLVSLCMLIAYYHL KVPLAIFKREKEIARRLEFDGLFIAEQPEDDDIKSHWDKLVISAKTFPVNYWDKFVKKKV RQKYSETYDFDSISNLLGMEKTAFAAQEANEGGGFFHFITNIDWRYQIWKAGVTITDNSF LYSLWYFSFSVMGNFNQFFFAAHLLDVAVGFKTLRTILQSVTHNGKQLVLTVMLLTIIVY IYTVIAFNFFRKFYVQEDDDGEEGDRKCHDMATCFVFHLYKGVRAGGGIGDEIGDPDGDE YEVYRILFDITFFFFVIVILLAIIQGLIIDAFGELRDQLESVKEDMESNCFICGIGKDYF DKVPHGFDTHVAQEHNLANYMFFLMHLINKPDTEYTGQETYVWNMYQQRCWDFFPVGDCF RKQYEDELGGGGS NT seq 15342 nt NT seq  +upstreamnt  +downstreamnt atggctgaagcagagggaggatccgagcaggatgatgtttcattcttgcgtacggaagac atggtctgcctgtcctgtacggcaaccggcgaacgcgtgtgtctggcggccgaaggtttc ggcaaccggcactgcttcctggagaacatcgcagacaagaacatcccgccggacctatcg cagtgcgtgttcgtcatagagcaggcgctgtcggtgcgtgcgctgcaggagctcgtcacg gccgccggttcggaaaccggaaacgattcggtaggaaagggtaccggatccggtcatcgt acgctgctttacggcaatgctatcctgttgcgtcacaacaacagtgacatgtatcttgcc tgtctgtcaacttcgtcctccaacgataagctgtcgtttgacgtcggtctgcaggagcac agccaaggtgaggcctgctggtggaccgtacacccagccagcaagcaacgttcggagggt gagaaggtccgtgtcggtgacgatctgattctggtgtccgtcgctaccgagcgatatctg cacacgaccaaagaaaacgatctgtcgatcgtaaatgctagcttccatgtgacgcactgg agcgtgcagccgtacggaaccggtatctcgcgcatgaagtatgtgggctacgtgttcggc ggcgacgttcttcggttcttccacggcggtgacgaatgtttaacgattccgagtacctgg agcttggactcgggtcagaacattgtcgtgtacgagggcggttctgtaatgtcgcaggcc cgctcgctgtggcgactcgagctggcccgcaccaagtgggccggtggcttcatcaactgg tcccatccgatgcgcattcgccatcttaccaccggccggtatctcggtgtgaacgaaaac aacgaactgatcctgatgagccgcgaccaagcgaccacctcgcagacggcctttgtgctg cgcctcgagaaggacgaccagaaggtggtgctggaggacaaggatttggaaattatcggt gccccgatcatcaagtacggcgactcgaccgtgatcatgcagcactacgagtcgggtctg tgggtcagctacaagagctacgaaacgaaaaagaagggcgtcggcaaggtggaggaaaag caggcgatactgcacgaggaaggcaagatggacgatgggttggacttttcgcgttcgcag gaagaggaatcgcgcacggctcgcgtcatccgcaagtgtagcagcttgttcaccaagttt attagtggccttgaaacgctgcaagaaaatcgtcgtcactcgattttcctgcagactgtc aacctgggtgagatggttatgtgtctggaggatctgatcaactacttcgcccagcccgag gacgacatggaacacgaggagaagcagaaccgcctgcgtgcgctgcgcaatcggcaggat ctgttccaggaggagggcgtactgaatctgatcctcgaagcgatcgacaagatcaacgtc atctcgtcgcagggctttttggcgtcgttcctggcgagcgacgaaagcggacagagctgg gacatgatctccggctatctgtatcagctgcttgccgccatcatcaagggaaaccacacg aactgtgcccaatttgccaactcgaaccggttgaactggttgttctcgcgacttggttcg caggcatcgagcgaaggttccggcatgctggatgtgttgcactgtgtgcttattgactcg cccgaagcgctgaacatgatgcgcgacgagcacatcaaggtgatcatttcgctgctggag aagcacggccgtgacccgaaggtactggacgtgctgtgctcgctgtgcgttggtaacggc gttgcggtgcgctcgtcgcagaacaacatctgcgactttctgctgccgggaaagaatctg ctcctgcagaccgggctcgtcgaccatgtggccagcattcggccgaacatttttgtgggg cgcgtggaaggatccgccatctaccagaagtggtacttcgaggtgacgatggatcacatc gagcagatgacgcacatgacgccacatctgcgcatcggttgggctaatacggctgggtac gtgccgtacccgggtggtggtgaaaaatggggcggcaacggtgtcggtgatgatctgttc tcgtacgggtttgacggtgtgtacttctggtccgctggacgacgcacctgcgtagtgccg agggaagtaacggaaccttttatcaagaaaggggacgtgattggctgtacgctcgatttg agtgtaccggtgattcggtttacctttaacggcgaaccggtgcagggttgcttcaccgac ttcaatctggacggtatgttcttccccgtgatgagctgctcgtccaagctaagctgtcgc tttctctttggcggtgacaatggacggctgaagtttaatccaccacccggcttttcgccg ctagttcagtgccttatgccacaccaaaaccttagcctggatccgtgcttttacttcggt aatctgaacaagaacgtgctcgccggcccatggttggtggaggacgattcggcgttcgtg ccgaaaccggtcgatacctcgatcgtcacattgccatcgtcggtggaaacgatcaaggac aagctggcagaaaacatccacgaaatgtgggcactgaacaagatcgaagccggctggacg tggggtgaacggagagacgatgtgtaccgcatacatccatgtctgacgtcgttcgagaag ctgccggcggcggaaaagcgctacgactgtcagctcgccgttcagacgctcaaaaccatc ctggcgctgggatactacatctcgatggacaagccaccggcacgcattcgtcccattcgc ctgccaaacgatccgtacatgcagggcaatggttacaaaccggccccgctcgatctgagt gccgccgtgctgacgcccaagatggaagagctggtcgatcaactggccgaaaacacgcac aacctgtgggcaaaagagcgcatccagcagggctggacgtacggattgaacgaggactcg gagaatctgcgtagcccgcatctcgtaccgtactcgaaggtggacgaagcgatcaagaaa gcgaaccgcgataccgcttccgaaacggtgcgcaccctgctgatctacggctacaatctg gatccgccaaccggtgaagccaacgaagcgctggcagcggaagcgttgcgtcagaagttt gccgcctaccgtacgtatcgtgtcgaacgaacgtatgcggtcacctctggcaagtggtac tttgagtttgaggtgcttactgccggtccgatgagggttggttgggcacgggctgactgt aatcccggaacgatgctgggaagtgacgatgcttcgtgggcattcgatggatacaatgca cgtaagatgcatctgcacacggtcgaagactttggtaaacgctataagatcggagacatc atcggttgcttcataaacgtccacgagaagagcatgagtttctcgctaaacggtgaactg ctgatggatgctcttggtggtgaaactacctttgctgatgtcaacgcaccggacggtgtt ggctttgtgccagcctgtactattggtatcggtcagaaagcgcgtgttgtttacggtcag gatgtagactctctcaagtggtttacaacctgtggtttgcaggaaggttacgaaccattc tgcgtcaacatgaagcgtcccgttacccattggtacacgaaggatcaaccaatcttcgag aatacggacgagattccggagtgcaagattgacgtgacgcgtatcccgggcggtgccgat acgccaccctgcatgaagatctcgcacaacacgttcgagacgatggaaaaggccaactgg gaatttttgcgtttgtcactccccgtaacatgcgccaataccttcattactgaacaggag aagatgcgccgctgggaagagatacgcatccgtcagcatcgtctaatgacggaggttgat cattcggctccggcacacttcgaccatatcatgcgcagtggcttcaccatgaacgatatc aagggtctgcatcgtaactattcggaagatgcggccgaagccgacgagatgatgcgcaac gggccaagacgcccgtcgagacaccagggacgcggtggacttagcccaccgggcattgaa atcaatggtgaggctacgagcgacggcgagcttaacgcgtactcggacaacgagctggag ggtggtgacgatcgcaaaaagcgtggccgcagtccgttccgactgttcggcaagaagcgg gaccagagcaaggataagctgaaagatcgtcgcacaccggagccggagccacgcaagagc aatctgaaggttactcagcgcggtcaggctacgcgcatgtcgaacagcgatctgcgtgcc caagcaccgttgacgccggagcgaaagggtatgggaagtccgcaggtggaatctttcggc aacgaagtctacgatgcagattgtttgcgcttaatcaatgagtacttctacggggtgcgc attttccccggccaagatccgacccacgtgtatgttggttgggtgacgacgcagtaccat gtgcatagcaaggagttcagccagaacaaggtgcgtcacgcagcgatctacgtcgaggac gagaatgagaaaaccattgagatcgttaatcgtcaatcgtgctatatggtgcgcgcggat gaactgttcaacgaagttacccaagattcgtctggtaagggcgcatcgcagggcatgttt gttggatgtttcgtcgataccgctaccggcacgatccggtttacgtgcgagggcaaggaa acgtcccacgtgttcctgatggagccggataccaagctgttcccggccatcttcgttgag gcgacgagcaaggaaattcttcagattgagctcggtcgcacaccgacgacgctgcctctg tcggctgccgtactgccaaccagcgacaagcatatcaacccacagttcccaccgagactg aaggtccaatgtttgaagccccaccagtgggcacgcgtaccgaatactgctttgcaggtg cacgccctgaagctgtcggacatccgcggttggtcgatgttgtgcgaggacccagtgtcg atgctggcactgcacatccccgaggaggatcgttgtatcgatattctcgagttgatcgaa atcgatcgtctgttgcagttccatgcacatacgctgacgctttattcggcactgtgctat cagtcgaactatcgtgccgcacatgcactttgctcgcacgtcgatcagaagcagctgttg tacgcgatccagtcggagtacatgagtggtccgctgcgtcttggattctatgatttatta atttcactgcatctagaatcgcatgccactacaatggaggtttgcaagaatgagtacatc attccgctaggctccgaactgcgcgagctatacattgatccagaaatgtgccattcgctc cgttcactgcaaacgctttccgttcgaccggaaatgaacatgaccgaaatagcacccaca ccctcacaatcgaatatgccgacaatagtagcaccagattcttccagtgaacccataccg gcaattgactcgttatattcgccaagattcccactcgaagtggtgagggagttcgtgatg agcgcactgcaggaagcagtacagatcaatcaggtacacaaccgcgatcccatcggtgga tctaacgagaaccttttcctgcccttgatcaagctgatcgatcgtttgctgttggtcggt gttatcactaacgaagatgtagagaagctactgatcatgattgatcccgagacgtgggat ccatctttcgaaaaggaaggtagggacgaacaccgtaagggattgttgacgatgaagatg gctgaaggtgccaagctgcagatgtgctacctgctgcaccatctgtacgatgtgcagctg agacatcgcgtggagagcattattgcattcgcgcacaactatgttggagatttgcagcag gatcagttgcgcagatacatcgagatcaaacaatctgatctgccgagtgccgttgctgcc aagaagacgcgagagttccgctgtccaccgcgcgagcagatgaacgccatccttggatac aagaatctcgaggaagatgatcttgagaatgcgtcttgcggtcccgagcttcgcaaccgt ttgatcgagttccacgagaagctaatgggcaaggtgtctcttaatgctttgcaagagcca gaggagcccgaggcggacaagctggaagagggtcgaccaggtgctctgaagaagttgtac aatttcatcaacgccgtgaaagagctggaagaagatcccaaggaaccggtcgaagaggaa aagaaaacgcccgaggaagtgttccgcaaggtgctgatcaagcagctcgtatcctgggcc gaagagtctcagattgagaatcccaagcttgtgcgtgagatgtttgggctgcttgtacgc cagtacgacaccatcggtgagctaatcaaggctctgaacaagacctacgtcatcaactcc aaaacgaagggtgatgtagcgaacatgtggattgggctgagtcaaattcgtgccttgctc ccggtacagatgagccaggaggaggaagagctgatgcgcaagcgtctgtggaagcttgtc aacaaccatactttcttccagcatcccgatttgattcgcattctgcgcgttcacgagaac gtgatggcggtcatgatgaacacgctcggacgccgtgcccaggcacagagcgatgcaccg gtgcagacggccgatggagaagagtcggcaccgaaggagaaggacacgtcccaccagatg gtggtagcttgctgtcgctttttgtgctacttctgtcgtactggtcgtatgaatcagaag gctatgttcgatcatttcgatttcttgttggaaaattccaacattctcctatcgcgacca agtctgcgcggatcgacgccattggatgtggcatactcgagtttgatggagaacacggag ttggcattggcactgcgtgagcactacttggagaagattgccatttacctgtctcgttgt gggttgcagagtaattccgagctgatcgagcgcggctaccccgatctcggctgggatccg gtggaaggcgagcgttatctcgatttcctgcgcttctgcgtgtgggttaacggggaaagt gtagaggagaatgccaatcttgttattcgtttgctcattcgtcgtcccgagtgtcttggc ccggctttgcgtggtgaaggtgagggtttgctgaaggccattgttgacgccaacaaaatg tccgaacgtatctcggagcgcagaaagatgcaggacgaagcggaaggtaccattactggg ctgaacttctcgcatccactccccgagggtgacgatgatgaggattatatcgacaccgga gctgccatcctgtgcttctactgtacgctggtcgatctgttgggacgctgtgctccggat gcggccgtcatcgagcagggcaagaatgagtctctgcgtgcgcgtgctattttacgttcg ctggtaccgctggaagatttgcagggagttttgagtttgaagtttacgctgaccaatcca gcactgggtgaagataggcccaagtcggacatgccgtctggattggtgcctggccacaag cagagcatcgtactgttcctggagcgtgtttacggaattgaaacgcaggagctgttctac cgcttgctggaagacgctttcctgcccgatctccgtgcggcaaccatgttggaccgtagc gatgggtcggaaagtgatatggctctgtcgatgaatcggtacattggcaattcgatcctt ccactgctgatcaaacactctaagttctacaacgaagccgaaaactatgccagcttgctc gatgccacactgcatacggtctatcgcatgtcgaagaaccgtatgctaaccaagggacag cgtgaagccgtgtctgatttcctggtcgcactgacgtcggccatgcatccggctatgtta ttgaagctgctccgcaagcttactatcgacgtttccaagctgtctgaatatacgaccgtt gcactgcgcctcttaaccctgcactacgaacgctgtgccaagtactacggcactaccggt ggtggtcaagcctcccagttcggtgcatcgtcggatgaggagaagcgtcttacgatgttg ctattctccaacattttcgattcgctcagcaacatggactacgatccggagctgttcggt aaggcgctgccgtgcttgattgcaatcggttgcgcactgccaccggactacagcttgtcc aagaactcggatgacgatctgtacggtaagccgacgggtggtggtcccgatcagccgcac tacaatccgcagccgatcgatacgacggcggttcagcttacgaacgatctgaaccagatt gtgcagaagttcagcgagcattatcatgacgcttgggctagccgtaagctcgagaacgga tggacgtacggtgaccaatggtcagatgcaaacaagactcatccacgtttgaagccgtac aatactctcagtgaatacgagcgtgaacgctatcgcgaaccagtacgggaaagcttgaag gcactgctggcgttgcactggagaatcgaacactcggagggtgatgtgccactgtcgaac cgtggttcgatgcgtcgccaatcgaagcctaatctggaattacagggcgacactggttct ccgttcaactacaatccgcacccggtcgacatgaccaacctgacgttgagcagagagatg caaaatatggccgaacgtttggcggagaattcgcacgacatatgggccaagaagaagaac gaagagctggaccagtgtggtggagctatccacgcccagctggtaccgtacgatctgctt accgacaaggagaagcgcaaggatcgcgagcgttcacaagaattcctgaagtatctgcag taccaaggactcaaactgcacaaaccatcgcgtggacaaactgaggagccgggcatgagc acggctgcgatcgagctgcgctttgcctactcactgctggagaagctgatctcctatagc gatcgtgctactatcaacatgaagctgctgaaaccatcgtctactttcagccgtcgttcg tccttcaagacctgctcacgcgacatcaagttcttctccaaggtggtactgccgctgatg gagaaatatttctccagcaatcgtaattacttcattgcgatcgctactgccaccaacaac gttggtgcggcttcactgaaggagaaggaaatggtggctggactgttctgtaagcttgcc agcttgttgcgtcaccggttggcagcattcggtgcggacgttcgcatcaccgtgcgctgt ctgcaggtgctagtgaagagtatcgatgccaaatcgttggtgaagaactgtcccgagttt attcgtacgtcgatgttgacgttcttcaacaacacggcggacgatttgggccaaacgatc gtcaacctgacggatggcaaatatgatcgtctgcgtggaacgcatctgaaaacttccact tcgttggcgtacgtcaatcaggtgatcttgccagtgttgacttcactgttcgatcatttg gcagcgtgcgactatggaagtgatttgttgttggacgaaattcaggtcgcatcgtacaaa atcctgtctgctctctacacactcggcaccgacacgtctttgacgcgcgatcgtaaatat cttaagaccgagctggaacgtcacaagcctgcccttggatcttgtctcggtgcgttcagt tcctgcttcccggtggctttccttgagccgcacgctaacaagcacaacccgttctcgcta ctgaaccgtattgccgatacctcactcgaggcgcaagacatcatgagcaagatggaatgc tgcatgccaacgctcgagtcgatcctgtccgaggtcgaccagtttgtcgagtcggaaaag acgtaccaggaggcacagcacatcattgatgtcattctgccgctgctctgttcctatttg ccgttctggtggaaccagggcccagacaacgttagcccgcagtcgggcaatcacgtcacg atggttacagccgatcacatgaaccatctgctgaagaacgtcctcaagatgattcgcaag aacattgccaacgagaacgcgccctggatgacgcgtatcgccacgtacacgcagcagatc attatcaacagctcggaggagctgctcaaggatgtcttcctaccgttggccgagcgggtc aagaaacgttgcgacagcatgttccacaaggaggaaagcttgcgtggtttcctcaagtct tccaccgatgatacctcccagattgaagcccaaatccaggaggactggcaactgctggtc cgcgatatctactcgttctatcccctgctgatcaagtacgtcgatctgcagcgtaaccat tggctcaaggataacgttgccgaggcggaggagctctacaactatgtggcggagatcttt aacgtttggtcgaagagccagtacttcctgaaggaagagcagaacttcatctcggcgaac gagattgacaatatgacattgatcatgcctacggcaacgcgccgctcagctgccgtctcg ggtgatatgcccgcgtccggcggtaaggtgaagaagaagaagcgcagccgcgataagaag cgtgacaaggataaggaaattcagtccagcttaatggtggcctgtctgaagcgtctgctg ccggttggtttgaatctgttcgccggtaaggaacaagagctggtgcagcactgcaaggat cgctatctaaagaaaatgcccgagtacgaggtgattgagtttgcgcgcacgcaactcacc ctgcccgacaagctcgatccagcggacgagatgtcctggcagcactatctatactcgaag ctcggcaaaaaggagcagattgtgcaggacacactggaaaagtcggacaagaagccggaa aacaagatcgaagacacggtcgagcgcatcgtcgccatggctaaggttctttatggactt cacatggcatgccgacctagagctaagggtcttaattggacacacgttttatcacaagca cgacgcaaaatggctgttgcatgtctaagagcaaaaccaatgtatagattgagcagacat cgtgcttgcaacatttttgcccgaagctactcggagctgtggctggaggatgaaaatacg ggccaagaggtcatgattgaggacctcacgcaaacatttgaggatgctgaaaagaagaag aaggatgaggaagaggaggaaggcaaaccggatccacttacgcagctcgtgacaacgttc tgccgtggtgcgatgactgaacgcagtggcgctttgcaggaagatcctctgtacatgtcc tacgctagcatcgttgcacgatcctgcggtgaagaggaggaggaaggtggcgacgaagaa gaaggagcaggagaggacgaaggaggtgctagtattcatgaacaagaaatggaaaagcag aagctcctgttccaccaggcacgtctggccaaccgtggcgtcgcggagatggtgctgctg cacatttccgcctcgaagggcgtcccgtccgagatggtgatgcgtacgctcgagctcgga attgccgtgctgcggggtggtaacatcgacatccagatgggaatgttgaaccatctgaag gaaaagaaggatgtcggattctttacctcgattgccggtttgatgaactcctgcagcgtg ctagatttagatgcgttcgaacgtaacaccaaggcggaaggtcttggcgtcggttcggac ggcgcagccggtgagaagaacatgcacgatgccgaatttacgtgcgcactgttccgcttc attcagctgacctgtgagggtcacaacctcgactggcagaactatctgcgtacgcaggcc ggtaacacgactacggttaacgtggtcatctgcacggtcgattatctgctgcgactgcag gaatcgatcatggacttttactggcactactccagcaaggaactgatcgacccggccggc aaggcgaactttttcaaggcaatcggtgtcgctagccaggtcttcaacacgctcactgaa gtcatccagggtccgtgtacgcagaaccagcaggcgctggcccactcgcgtctttgggat gcggtcggtggtttcctcttcctgttctcccacatgcaggacaaactgtcgaaacactct agccaggtggatctgctgaaggagctgctcaatctgcagaaggacatgatcaccatgatg ctctccatgcttgagggtaacgtggtaaacggtacgatcggtaagcagatggtggacacg ctggtcgagtcggcctcgaacgtcgagctgattctgaagtacttcgacatgttcctgaag ctgaaggatctgacctccacgccaagcttcatggagattgatagcaacggggacggttgg attatgccgaaagatttccgcgaaaagatggaacagcagaagagctacacgccggaggag atcgacttcctgctcgcttgctgcgagacaaaccatgacggaaagatcgactacatcggt tttgtcgatcggttccacgagccggccaaggagattggtttcaatctggccgtcctgctg acgaacctgtccgagcacatgccgaacgaaccgcggttggcccggttcctcgagacggcc ggttccgtgctgaactacttcgagtcgttcttgggccgtatcgaaattatgggctcgtcc aagcgcatcgagcgcgtgtacttcgaaatcaaggaagcgaacatcgaacagtgggagaag ccgcagatcaaggaatcgaagcgtgccttcttctactcgatcgtcacggaaggtggcgat aaggagaagctggaagcgttcgtcaacttctgcgaggatgccatctttgaaatgacgcac gcctccggactgatggcgagcgatgacgacggtggcaccgtgcgccgtgatcaggcgttc acgtacatcagcgaggaggaggaggagcgtgccgcccgcgatccgatcaagcgcaccatc caggccgtcaaggacggtctgtcatactcgatgtacatgatcagcccgtccaacatcaag caccagattaccgtactgcagtcgaaatcattccccgagattatagtcggattcttcaag atgatcttctacgcgttctactactctggctttggcgtgtcggttgtgattaaatacttg gtgaacatcctgatgtcgctcatgcgcggcccggcccaggaggaggaagaaccgatcccg gaggcggaaccatccctgcgtgcactgccaccactaccgctggaggagccgccaggtacg gtgcaggcgttcggtttggacatcagcaaggaagagaatggacagtaccgcatggcaccg cacgagtcgcccgccctcagcccgtcgtcctcgatcgaggaaacgggtgagtccagcccc gaggatggagcggccgagctgacgggcgaaggtgtaccaccgggcgaacagatgacgctg gtcgatctgctcggcggtgaagccgccaaacgtgccgctcaggaacgcacggaagcgcaa aaggcacaggaagctaccctcgccagcattgaggcggagtcgaagaaggcttcaaccgaa acgaaggaacccgcggccgtccaccagatcgatttctccaaatacacgaagaagtgcgtc agctatctggcgcgtaacttctacaacctgaagtacgtggcgctggtgttggcgttctgc atcaactttatgctgctgttctacaaggtgacgacgctcggcgacgacgaggacggtgag ggcggttcgggcgaaagtctgatgggactcggatcgggcctgggatcgggacttggcatt ttggaaacgggctcgggcggcggtgaaggtggaagcggcgatggcgaaggcgaagaggaa gacccaccggagaaggtgcatgtagatgaggacttcttctacatggagcacgtgctgcgt atcgctgccatcctgcacagtctggtgtcgctctgcatgctgatcgcttactaccatctg aaggtaccgctggccatcttcaaacgcgagaaggaaatcgctcgtcggctcgagtttgac ggactgttcattgccgagcagccggaggacgacgacatcaaatcgcactgggacaagctg gtgatatccgccaaaacgttcccggttaactactgggacaagttcgtaaagaagaaggtc cgccagaagtatagcgaaacgtacgacttcgactcgatctcgaacctgctcggcatggaa aagacggcgtttgcggcacaggaagcgaacgagggcggtggcttcttccacttcattacg aacatcgactggcgctaccagatctggaaggcgggcgtgacgatcacggacaactcgttc ctgtactcgctctggtacttctcgttttcggtgatgggcaacttcaaccagttcttcttc gccgcccatctgctcgatgtggcggtcggcttcaagacgctgcgtaccattctgcagtcg gtaacgcacaacggcaagcagctggtgctgaccgtaatgctgctcacgatcatcgtgtac atctacacagttatcgcgtttaacttcttccgcaagttctacgtgcaggaggatgacgat ggagaggagggcgaccgcaagtgtcacgatatggcgacctgcttcgtgttccatctgtac aagggtgtgcgggcgggtggtggtatcggtgacgagatcggcgatccggacggcgacgag tacgaggtgtaccgtatcctgttcgacatcacgttcttcttcttcgtcatcgttatcctg ctggccatcatccagggtttgatcatcgatgcgttcggtgagcttcgtgaccagctcgaa tcggtcaaggaggatatggagtccaactgcttcatctgtggcataggcaaggactacttt gataaggtacctcacgggttcgatacgcacgtcgcccaggagcacaatctcgccaactac atgttcttcctgatgcatttaatcaacaaaccagacacggagtacaccggtcaggagacg tacgtgtggaatatgtatcagcagcgatgctgggacttcttccccgtcggtgactgcttc agaaagcagtacgaagatgagctgggtggtggcggtagctaa

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