Actinoalloteichus sp. AHMU CJ021: C1701_20060
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Entry
C1701_20060 CDS
T05306
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
acta
Actinoalloteichus sp. AHMU CJ021
Pathway
acta00300
Lysine biosynthesis
acta00550
Peptidoglycan biosynthesis
acta01100
Metabolic pathways
acta01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
acta00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
C1701_20060
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
C1701_20060
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
C1701_20060
Enzymes [BR:
acta01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
C1701_20060
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Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
Motif
Other DBs
NCBI-ProteinID:
AUS80245
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Position
4719311..4720834
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AA seq
507 aa
AA seq
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MIRLSLAEIARAVGGRPHGCEGSVEVTGSVEFDSRKVGPGGLFVALPGERVDGHDFAARA
VSQGAVAVLAAHEVDAPAIIVPPVAAGSGPSGNPMVLAADVAGEGAAVLAALAALARDVT
DRLTAPGRPEGNLTVVGITGSSGKTSTKDLVAQVLGPLGPTVAPPGSFNNEIGHPWTVLR
ADERTRHLVLELSARGEGHIAALCEAAPPRIGVVLNVGSAHLGEFGSREAVARAKGELPA
ALPSAAEGGVAVLNADDPLVAAMAERTTARVVRVGLAPSADVRAEDVVLDDQARASFRLV
TPRGSAPVRLGLHGAHQVGNALAAAAVALECGAEVTDVAASLSSAVRRSPRRMEVTDRAD
GVTVVNDSYNANPESVRAALKTLATMARDAPAGRRRSWAVLGPMGELGEDSTTAHDEIGR
LAVRLDISRLVVVGEEARPMYQGACLEGSWGEEAVLVPDVGSAARLLEEELRPGDVVLVK
ASKVAELWRVAESLLAGERGGAAGGAA
NT seq
1524 nt
NT seq
+upstream
nt +downstream
nt
gtgatcaggctcagcctggctgagatcgccagggccgtcggtggacggccgcacggctgc
gagggctcggtcgaggtgaccgggtcggtggagttcgactccaggaaggtcgggccaggc
ggcctgttcgtggcgctgcccggggaacgggtcgacggccacgacttcgccgcgcgagcc
gtgagccagggagcggtggccgtactggcggcccacgaggtcgacgcccccgccatcatc
gtcccgccggtcgccgcgggctccggcccgagcggcaaccccatggtgctggccgcggac
gtcgcgggggagggcgcggcggtcctcgccgccctggccgccctggccagggacgtcacc
gaccggctgacggcacccggtcgacccgaggggaacctgacggtggtggggatcaccggg
tcctccggcaagacctccaccaaggacctggtggcccaggtcctgggacccctcggcccg
accgtggcgccgcccggctcgttcaacaacgagatcggccacccctggaccgtgctgcgc
gccgacgagcgcacccggcacctcgtcctggagctgtcggcgcggggcgaggggcacatc
gcggccctgtgcgaggccgccccgccccggatcggggtcgtgctcaacgtgggcagcgcc
cacctcggcgagttcggctcccgggaggcggtggccagggccaagggagagctgcccgcc
gcgttgccgtccgccgccgagggtggcgtcgccgtgctcaacgccgacgaccccctggtg
gcggcgatggcggagcggacgaccgcccgggtcgtccgggtcgggctcgcgccctccgcc
gacgtccgggcggaggacgtggtcctcgacgaccaggccagggccagcttccggctggtg
acaccgcgcggatcggcaccggtgcgcctcggcctgcacggagcccaccaggtcggcaac
gccctggccgccgcggccgtcgccctcgagtgcggagccgaggtcaccgacgtcgcggcc
tcgctgtcctcggcggtccgccggtccccgaggcggatggaggtcaccgaccgcgccgac
ggggtgaccgtcgtcaacgactcctacaacgccaacccggaatcggtccgggcggcgttg
aagaccctcgccaccatggcgcgggacgcccccgccggtcgacgtcgcagctgggctgtg
ctggggccgatgggcgagctgggcgaggactccaccaccgcgcacgacgagatcggccgg
ttggcggtgcggctggacatcagccgcctggttgtagtcggtgaggaggcccgccccatg
taccagggcgcgtgcctggaaggttcctggggcgaggaggcggtactggtgcccgacgtc
ggatcggcggcgcggctcctggaggaggagctgcggccgggtgacgtggtcctggtgaag
gcgtcgaaggtcgccgagctgtggcgggtcgccgagagcctgctggccggtgagcgtggc
ggcgccgcgggaggtgccgcgtga
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