Actinomyces sp. HMT897: JJJ15_02355
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Entry
JJJ15_02355 CDS
T10470
Symbol
leuC
Name
(GenBank) 3-isopropylmalate dehydratase large subunit
KO
K01703
3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:
4.2.1.33
4.2.1.35
]
Organism
acth Actinomyces sp. HMT897
Pathway
acth00290
Valine, leucine and isoleucine biosynthesis
acth00660
C5-Branched dibasic acid metabolism
acth01100
Metabolic pathways
acth01110
Biosynthesis of secondary metabolites
acth01210
2-Oxocarboxylic acid metabolism
acth01230
Biosynthesis of amino acids
Module
acth_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
acth00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00660 C5-Branched dibasic acid metabolism
JJJ15_02355 (leuC)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
JJJ15_02355 (leuC)
Enzymes [BR:
acth01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.33 3-isopropylmalate dehydratase
JJJ15_02355 (leuC)
4.2.1.35 (R)-2-methylmalate dehydratase
JJJ15_02355 (leuC)
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Motif
Pfam:
Aconitase
Motif
Other DBs
NCBI-ProteinID:
QQO78218
UniProt:
A0A974RUP0
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Position
complement(569760..571313)
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AA seq
517 aa
AA seq
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MGMTLAEKVWRDHVVTQGADGAPDLLYIDLHLVHEVTSPQAFEGLRLAGRQVRRPDLTLA
TEDHNTPTLDIDLPIADPTSRTQIETLRRNCAEFGVRLHSLGDADQGIVHAVGPQLGLTQ
PGMTVVCGDSHTSTHGAFGALAFGIGTSQVEHVLATQTLPIAPFRTMSVTIDGDLPAGSG
AKDIILAIIAKIGTNGAQGHVIEYRGRAIEQLSMEARMTICNMSIEGGARAGMIAPDAVT
YDYLAGRPHAPVGADWDAAVAYWDSLRTDADAVFDTEVVLEAADIEPFVTWGTNPGQGLP
ISAAVPDPEDIADATERLAAQRAIEYMDLTPGTPLRQIPVDAVFVGSCTNGRIEDLRTAA
EVVRGRTKAPGLRMLVVPASARIRLQAEAEGLDQVFKDFGAEWRNAGCSMCLAMNPDKLA
PGERAASTSNRNFEGRQGKGGRTHLVSPAVAAATAVRGTLSSPADLPPLPARPATAPAPG
VPAPGPALVDGPVPVAGPAPAPGPAPAAVTLPVPAAA
NT seq
1554 nt
NT seq
+upstream
nt +downstream
nt
atgggtatgaccctggctgagaaggtctggcgcgaccacgtcgtgacccagggtgccgac
ggcgcccctgacctgctctacatcgacctccacctcgtccacgaggtcaccagcccccag
gccttcgagggcctgcgcctggccggccgccaggtccgccgccccgacctgaccctggcc
accgaggaccacaacacccccaccctggacatcgacctgcccatcgccgaccccacgtcc
cgcacccagatcgagaccctgcgacgcaactgcgccgagttcggggtgcgcctgcactcc
ctgggcgacgccgaccagggcatcgtccacgccgtcggcccccagctgggcctgacccag
cccggcatgacggtggtgtgcggggactcccacacctccacccacggcgccttcggggcc
ctggccttcggcatcggcacctcccaggtggagcacgtcctggccacccagaccctgccc
atcgcccccttcaggaccatgagcgtgaccattgacggcgacctgcccgcgggcagcggg
gccaaggacattatcctggccattatcgccaagatcggcaccaacggcgcccagggccac
gtcatcgagtaccgcggccgcgccatcgagcagctctcgatggaggcccgtatgaccatc
tgcaacatgagcatcgagggcggggcccgcgccggcatgatcgcccccgacgccgtcacc
tacgactacctcgccgggcggccccacgcccccgtcggcgcggactgggacgccgccgtg
gcctactgggactccctgcgcaccgacgccgacgccgtcttcgacaccgaggtggtcctg
gaggccgccgacatcgagcccttcgtcacctggggcaccaaccccggccagggcctgccc
atctcggcggccgttcccgaccccgaggacattgccgacgccaccgagcgcctcgccgcc
cagcgcgccatcgagtacatggacctgacccccggcacgcccctgcgccagatcccggtc
gacgccgtcttcgtgggaagctgcaccaacgggcgcatcgaggacctgcgcaccgccgcc
gaggtggtccggggccgcactaaggcccccggcctgcgcatgctggtggtgcccgcctcg
gcccgcatccgcctccaggccgaggccgagggcctggaccaggtcttcaaggacttcggc
gccgagtggcgcaacgccgggtgctccatgtgcctggccatgaaccccgacaagctcgcc
cccggggagcgcgccgcctccacctccaaccgcaacttcgaggggcgtcagggcaagggc
gggcgcacccacctggtctccccggcggtggccgcggccaccgcggtgcgcggcaccctg
tccagccccgccgacctgccgcccctgcccgcccgcccggccaccgccccggcacccggg
gtccctgcgcccgggcccgccctggtggacgggcccgtcccggtggccggacccgccccg
gcacccgggcccgccccggccgccgtcaccctgcccgtccccgccgcggcctga
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