Actinoplanes sp. N902-109: L083_4146
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Entry
L083_4146 CDS
T02655
Name
(GenBank) bifunctional uroporphyrinogen-III synthetase/response regulator domain-containing protein
KO
K01719
uroporphyrinogen-III synthase [EC:
4.2.1.75
]
Organism
actn
Actinoplanes sp. N902-109
Pathway
actn00860
Porphyrin metabolism
actn01100
Metabolic pathways
actn01110
Biosynthesis of secondary metabolites
actn01120
Microbial metabolism in diverse environments
actn01240
Biosynthesis of cofactors
Module
actn_M00846
Siroheme biosynthesis, glutamyl-tRNA => siroheme
actn_M00926
Heme biosynthesis, bacteria, glutamyl-tRNA => coproporphyrin III => heme
Brite
KEGG Orthology (KO) [BR:
actn00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00860 Porphyrin metabolism
L083_4146
Enzymes [BR:
actn01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.75 uroporphyrinogen-III synthase
L083_4146
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Gene cluster
GFIT
Motif
Pfam:
HEM4
Trans_reg_C
Germane
PrpF
Motif
Other DBs
NCBI-ProteinID:
AGL17656
UniProt:
R4LKV5
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All DBs
Position
complement(4856411..4857523)
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AA seq
370 aa
AA seq
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MTTSQAAEAAPLTGFTVAVTAERRRDELAALLERRGARVVVAPAITIVPLGDDEALHAAT
AACVGLAPDIVIATTGIGFRGWLEAAEGWGMGDTLRAALGRARLIARGAKPCGAIRAADL
SEEWSAVTESSEEILDRLLAQGIAGRRIAVQLHGGAQDEFTGALRAAGAAVVEVPVYRWT
LPGDVAPVRRLVGQLTAGQIDAVTFTSAPAVQALLEIAGDEAGRVLDRFRASTMAACVGP
VTAASLIKQDVPVVMPHRSRLGALVKTVTDELPARAVRLSVAGEPLEIRGHAVVVGGRLQ
TLAPVAMAILGALAARPGAVVPKDKLAAALPRGTDSHAVDVAIARLRTALGGGGHIETVI
KRGYRLRVDE
NT seq
1113 nt
NT seq
+upstream
nt +downstream
nt
gtgaccaccagtcaggctgccgaggccgcgccgctcaccgggttcaccgtggccgtcacc
gcggaacggcggcgcgacgagctggccgccctgctcgaacggcgtggcgcgcgggtggtg
gtggcgcccgcgatcaccatcgtgccgctcggcgacgacgaggcgctgcatgccgcgacc
gccgcctgcgtgggcctggctcccgacatcgtcatcgccaccaccggcatcggcttccgc
ggctggctggaggcggccgagggctgggggatgggcgacacgctgcgggcggcgctgggc
cgggcccggctgatcgcccgcggggcgaaaccgtgcggggcgatccgggccgccgacctg
agcgaggagtggtcggcggtcaccgagtcgtccgaggagattctcgaccggctgctggcg
cagggcatcgccggccggcgcatcgcggtgcagctgcacggcggggcgcaggacgagttc
accggggcgctgcgcgcggccggggcggcggtggtggaggtgccggtctaccgctggacg
ctgcccggagacgtcgcgccggtgcgccggctggtcggccagctcaccgccgggcagatc
gacgcggtcacgttcaccagcgcccccgcggtgcaggcgctgctggagatcgccggggac
gaggccggtcgggtgctggaccggttccgggcgtcgacgatggccgcgtgcgtcgggccg
gtgaccgccgcgtcgctgatcaagcaggacgtgccggtggtgatgccgcaccgctcccgg
ctcggcgcgctggtcaagacggtgaccgacgagctgcccgcgcgggcggtgcggttgtcg
gtggccggcgagccgctggagatccggggccatgcggtggtggtcggcgggcggttgcag
acgctggccccggtggcgatggcgatcctgggggcgctggccgcacgcccgggtgcggtg
gtgcccaaggacaagctggcggctgcgctgccgcggggcaccgacagccatgcggtggac
gtggcgatcgcccggctgcggaccgcgctgggcgggggcgggcacatcgagaccgtcatc
aagcgggggtaccggctgcgggtggacgaatga
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