Actinoplanes sp. SE50: ACWT_1636
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Entry
ACWT_1636 CDS
T05392
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
acts
Actinoplanes sp. SE50
Pathway
acts00300
Lysine biosynthesis
acts00550
Peptidoglycan biosynthesis
acts01100
Metabolic pathways
acts01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
acts00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
ACWT_1636
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
ACWT_1636
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
ACWT_1636
Enzymes [BR:
acts01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
ACWT_1636
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GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
CbiA
Motif
Other DBs
NCBI-ProteinID:
ATO81051
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Position
1870435..1871826
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AA seq
463 aa
AA seq
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MIPMTLAEIAAVTGGHLVNSDGSETVTGGVEYDSRRVGPGGLFVAFAGEKADGHDFGPKV
VAAGAAGVLGTRDAGAPGVVVEDQLAALAKLAHEVLTRLPELTVVGLTGSSGKTTTKDYL
GQLLSRLGPTVAPAGSLNNELGFPYTVLQAGRETRFLVLEMGARGIGHIRYLTGIARPSI
GLVLNVGAAHLGEFGSIEGTARAKGELVEALPADGVAVLNADDPLVAAMASRTGARVLRV
GEAADADLRATGVTVDSAGRASYVLHHGLEVRNVRLGVAGRHQVANSLAAAAAALTAGMP
LDDLATALGEVGIVSGRRMDVIERPDGVTVVDDSYNANPSSTAAALHALAAMGAGKRTTA
VLGYMAELGEHEVSGHAEVGRLAAELGVDRLIAVADNARPILDGAAAAPGWRGTALFAAD
QAAAIEILQSDLRADDVVLVKGSRYRTWDVADWLRRPEEVQPT
NT seq
1392 nt
NT seq
+upstream
nt +downstream
nt
atgatcccgatgacactggccgagatcgccgccgtgaccggcggccacctggtcaacagc
gacggctcggagacggtcaccggcggcgtggagtacgactcccgccgggtgggcccgggc
gggctgttcgtggcgttcgccggggagaaggcggacgggcacgacttcggcccgaaggtg
gtcgcggccggggcggccggggtgctcggcacccgggacgccggcgcgcccggggtggtg
gtcgaggaccagctggccgcgctcgcgaagctggcccacgaggtgctcacccggctgccc
gagctgaccgtggtgggcctgaccggctcgtccggcaagaccaccaccaaggactacctg
gggcagctgctgtcccggctggggcccaccgtggcgccggccggctcgctcaacaacgag
ctcggcttcccgtacacggtgctgcaggccggccgggagacccggttcctggtgctggag
atgggcgcccggggcatcgggcacatccggtacctgaccgggatcgcccggccgtcgatc
ggcctggtgctcaacgtgggtgccgcgcacctcggcgagttcggctcgatcgagggcacc
gcgcgggccaagggcgagctggtcgaggcgctgccggcggacggggtcgcggtgctcaac
gcggacgacccgctggtcgcggcgatggcgtcgcggaccggggcgcgggtgctgcgggtc
ggcgaggcggccgacgccgatctgcgcgccacgggggtcacggtggactcggcggggcgg
gcgtcgtacgtcctccatcatggtcttgaagtgaggaatgtccggctcggcgtggccggg
cggcatcaggtggcgaactcgctggccgccgcggcggccgcgctgaccgccgggatgccg
ctggacgacctggccaccgcgctcggcgaggtgggcatcgtctccgggcggcggatggac
gtgatcgagcggccggacggggtgacggtcgtcgacgactcgtacaacgccaatccgtcg
tcgaccgcggcggcgctgcacgcgctggccgcgatgggcgccgggaagcgcaccaccgcc
gtgctcggctacatggccgagctcggcgagcacgaggtgtccgggcatgccgaggtcggc
cggctcgccgccgaactgggtgtggaccggctgatcgcggtggcggacaacgcccgcccg
atcctggacggagccgcggcggcacccgggtggcgggggaccgccctgttcgccgccgac
caggccgccgccatcgagattctgcagtccgacctgcgcgccgacgacgtcgtgctggtc
aagggttcccggtaccgcacatgggacgtcgccgactggctgcggcgccccgaggaggtt
cagcccacgtga
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