Actinoplanes sp. SE50: ACWT_7730
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Entry
ACWT_7730 CDS
T05392
Name
(GenBank) uroporphyrin-III C-methyltransferase
KO
K13542
uroporphyrinogen III methyltransferase / synthase [EC:
2.1.1.107
4.2.1.75
]
Organism
acts
Actinoplanes sp. SE50
Pathway
acts00860
Porphyrin metabolism
acts01100
Metabolic pathways
acts01110
Biosynthesis of secondary metabolites
acts01120
Microbial metabolism in diverse environments
acts01240
Biosynthesis of cofactors
Module
acts_M00121
Heme biosynthesis, plants and bacteria, glutamate => heme
acts_M00846
Siroheme biosynthesis, glutamyl-tRNA => siroheme
acts_M00926
Heme biosynthesis, bacteria, glutamyl-tRNA => coproporphyrin III => heme
Brite
KEGG Orthology (KO) [BR:
acts00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00860 Porphyrin metabolism
ACWT_7730
Enzymes [BR:
acts01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.107 uroporphyrinogen-III C-methyltransferase
ACWT_7730
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.75 uroporphyrinogen-III synthase
ACWT_7730
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Gene cluster
GFIT
Motif
Pfam:
HEM4
TP_methylase
B12-binding
Motif
Other DBs
NCBI-ProteinID:
ATO87145
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Position
complement(8673848..8675434)
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AA seq
528 aa
AA seq
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MTTRTARKPAGRIAFIGAGPGDPELLTRRAYAALTDADQVVHDRGVPESLLAAVRADAKP
DAQFSPAEGAPGDVAKVLLSAAKSGLSAVHLVAGDPFGHESVVKEVQAVARTAVHFEVIP
GIGQAEGVAAYAGVPLPGVRIAADVDDVTSLDFDALAGAAQKGSFAVAVDAGDLAAVRDG
LLAAGVEPGVPVAVTGDGTGETQYTTTSTVDSFVAAALGFTGRVVLTVGAEVAERDAMSW
WENRPLYGWKVLVPRTKEQAGAMSARLRAYGAIPCEVPTIAVEPPRTPAQMERAVKGLVD
GRYAWVVFTSVNAVRAVWEKFAEHGLDARHFGGVKIACIGEATAEAVRDFGIQPELIPAG
EQSSEGLLAEFSPHDEILDPVGRVLLPRADIATETLAAGLIERGWEVDDVTAYRTVRAAP
PPAEIRDAIKSGGFDAVLFTSSSTVRNLVGIAGKPHARTVVAVIGPKTAETAVEFGLRVD
TQPQNASVPDLVEALAEYALELREKLAAMPAKQRRGSKVQGPTALRFR
NT seq
1587 nt
NT seq
+upstream
nt +downstream
nt
atgaccacccgcaccgcccgtaagccagccggacgcatcgcgttcatcggcgccggaccc
ggcgacccggagctgcttacccgccgcgcgtacgccgcgttgaccgatgccgaccaggtg
gtccacgaccggggcgtacccgagtcgctgctggccgcggtccgcgcggacgccaaaccc
gacgcgcagttcagcccggccgagggcgcccccggcgacgtggccaaggtgctgctctcc
gccgccaagtccgggctgtccgccgtccacctggtggccggcgacccgttcggccacgag
tcggtggtcaaggaggtgcaggcggtcgcccggaccgcggtgcacttcgaggtgatcccg
ggcatcgggcaggccgagggtgtcgccgcgtacgccggcgtgccgctgcccggcgtgcgg
atcgccgccgacgtcgacgacgtcacctcgctcgacttcgacgcgctggccggcgcggcc
cagaagggctcgttcgcggtcgccgtggacgccggcgacctcgccgcggtccgcgacggg
ctgctcgcggccggcgtcgaaccgggtgtcccggtcgcggtgaccggcgacggcaccggc
gagacgcagtacaccaccacctcgacggtggacagcttcgtggccgccgcgctcggcttc
accggccgggtggtgctcaccgtcggggccgaggtcgccgagcgggacgcgatgagctgg
tgggagaaccgcccgctgtacggctggaaggtcctggtcccgcggaccaaggagcaggcc
ggcgcgatgagcgcgcggctgcgggcgtacggcgccatcccgtgcgaggtgccgaccatc
gcggtcgagccgccgcgcaccccggcgcagatggagcgcgcggtcaagggcctggtcgac
ggccgctacgcctgggtggtgttcacctcggtgaacgccgtccgcgcggtctgggagaaa
ttcgccgagcacggcctcgacgcccgtcacttcggcggtgtgaagatcgcctgcatcggg
gaggccaccgccgaggcggtccgcgacttcggcatccagcccgagctgatcccggccggc
gagcagtccagcgagggcctgctggccgagttctcgccgcacgacgagatcctcgacccg
gtcggccgggtgctgctgccgcgcgccgacatcgccaccgagaccctggccgccggcctg
atcgagcggggctgggaggtggacgacgtgaccgcgtaccggacggtgcgggccgcgccg
ccgccggccgagatccgcgacgcgatcaagtccgggggcttcgacgcggtgctgttcacc
tcgtcctccacggtccgcaacctggtcggcatcgccggcaagccgcacgcccgcacggtc
gtcgcggtgatcgggccgaaaaccgcggagaccgcggtcgagttcggcctgcgggtcgac
acccagccgcagaacgcctcggtgccggacctggtcgaggcgctcgccgaatacgccctg
gagctgcgcgagaaactggcggcgatgcccgccaagcagcgccgcggctcgaaggtgcag
ggcccgacggccctccgattccgctga
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