Actinomadura sp. WMMB 499: F7P10_33640
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Entry
F7P10_33640 CDS
T06213
Symbol
leuC
Name
(GenBank) 3-isopropylmalate dehydratase large subunit
KO
K01703
3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:
4.2.1.33
4.2.1.35
]
Organism
actw
Actinomadura sp. WMMB 499
Pathway
actw00290
Valine, leucine and isoleucine biosynthesis
actw00660
C5-Branched dibasic acid metabolism
actw01100
Metabolic pathways
actw01110
Biosynthesis of secondary metabolites
actw01210
2-Oxocarboxylic acid metabolism
actw01230
Biosynthesis of amino acids
Module
actw_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
actw00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00660 C5-Branched dibasic acid metabolism
F7P10_33640 (leuC)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
F7P10_33640 (leuC)
Enzymes [BR:
actw01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.33 3-isopropylmalate dehydratase
F7P10_33640 (leuC)
4.2.1.35 (R)-2-methylmalate dehydratase
F7P10_33640 (leuC)
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Motif
Pfam:
Aconitase
AcnX
Motif
Other DBs
NCBI-ProteinID:
QFG25365
UniProt:
A0A5J6UEH9
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All DBs
Position
7463185..7464582
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AA seq
465 aa
AA seq
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MGRTLAEKVYDAHVVRRAEGEPDLLYIDLHLVHEVTSPQAFDGLRMNGRQVRRPDLTIAT
EDHNVPTTDLLKPIADPVSRTQVETLRKNCSDFGVRLHPMGDDGQGIVHVIGPQLGLTQP
GMTVVCGDSHTSTHGAFGALAFGIGTSEVEHVLATQTLPQVQPKTMAVTVEGELPAGVTA
KDLILAIIARIGTGGGQGHIIEYRGEAVRSLSMEGRMTVCNMSIEAGARAGMIAPDETTF
EYIKGRPHAPEGADWDAAVEYWTSLRTDDDAVFDKEIVIDAAALTPFVTWGTNPGQGLPL
GESVPDPASFADPVDRQAAERALEYMGLTAGTPLRDVAVDTVFVGSCTNGRIEDLRAVAD
VLKDRRVADGVRMLVVPGSMKVKKQAEDEGLDEVISASGAEWREAGCSMCLAMNPDKLAP
GERSASTSNRNFEGRQGPGGRTHLVSPAVAAATAVTGRLAAPADL
NT seq
1398 nt
NT seq
+upstream
nt +downstream
nt
atgggccggacactggccgagaaggtgtacgacgcgcacgtcgtacggcgtgccgagggc
gagcccgacctcctctacatcgacctgcatctggtgcacgaggtcaccagcccgcaggcg
ttcgacgggctgcggatgaacgggcggcaggtccgccgacccgacctgacgatcgccacc
gaggaccacaacgtcccgacgaccgacctgctcaagccgatcgccgacccggtgtcgcgc
acccaggtcgagacgctgcgcaagaactgctccgacttcggcgtccggctgcatccgatg
ggcgacgacgggcaggggatcgtccacgtcatcggcccgcagctcgggctgacccagccc
ggcatgacggtcgtgtgcggcgactcgcacacctccacgcacggcgcgttcggcgcgctc
gcgttcggcatcggcaccagcgaggtcgagcacgtcctcgccacccagacgctgccgcag
gtccagccgaagacgatggccgtcaccgtcgagggggaactgcccgccggcgtcaccgcc
aaggacctcatcctggcgatcatcgcccggatcggcaccggcggcggccagggccacatc
atcgagtaccgcggcgaggccgtccgctcgctgtcgatggaaggccgcatgacggtctgc
aacatgtcgatcgaggccggtgcccgcgcgggcatgatcgccccggacgagacgacgttc
gagtacatcaagggccgcccgcacgcgcccgagggcgccgactgggacgcggccgtcgag
tactggacgtccctgcgcaccgacgacgacgcggtcttcgacaaggagatcgtcatcgac
gccgccgcgctcaccccgttcgtcacctggggcaccaaccccggccagggcctcccgctc
ggcgagtccgtgcccgaccccgcgtccttcgccgacccggtcgaccggcaggccgccgag
cgcgccctcgagtacatgggcctcaccgccgggacgccgctgcgcgacgtcgccgtcgac
acggtgttcgtcggctcctgcaccaacggacgcatcgaggacctgcgcgccgtcgcggac
gtcctcaaggaccgccgggtcgccgacggcgtccgcatgctggtcgtccccggctccatg
aaggtcaagaagcaggccgaggacgaggggctcgacgaggtcatctccgcctcgggcgcc
gagtggcgggaggcgggctgctcgatgtgcctggccatgaaccccgacaagctcgccccg
ggcgagcgcagcgcctcgacgtccaaccgcaacttcgagggccggcagggccccggcggc
cgcacgcacctggtgtcgcccgccgtcgccgccgccaccgccgtcaccggccgcctcgcc
gctcccgccgacctctaa
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