Actinomadura sp. WMMB 499: F7P10_33680
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Entry
F7P10_33680 CDS
T06213
Name
(GenBank) D-alanine--D-alanine ligase
KO
K01921
D-alanine-D-alanine ligase [EC:
6.3.2.4
]
Organism
actw
Actinomadura sp. WMMB 499
Pathway
actw00470
D-Amino acid metabolism
actw00550
Peptidoglycan biosynthesis
actw01100
Metabolic pathways
actw01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
actw00001
]
09100 Metabolism
09106 Metabolism of other amino acids
00470 D-Amino acid metabolism
F7P10_33680
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
F7P10_33680
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
F7P10_33680
09180 Brite Hierarchies
09181 Protein families: metabolism
01011 Peptidoglycan biosynthesis and degradation proteins [BR:
actw01011
]
F7P10_33680
Enzymes [BR:
actw01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.4 D-alanine---D-alanine ligase
F7P10_33680
Peptidoglycan biosynthesis and degradation proteins [BR:
actw01011
]
Precursor biosynthesis
Amino acid ligase
F7P10_33680
BRITE hierarchy
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Paralog
Gene cluster
GFIT
Motif
Pfam:
Dala_Dala_lig_C
Dala_Dala_lig_N
ATP-grasp
CPSase_L_D2
ATP-grasp_4
Motif
Other DBs
NCBI-ProteinID:
QFG25372
UniProt:
A0A5J6UEA4
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All DBs
Position
7469340..7470458
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AA seq
372 aa
AA seq
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MSHSKIRVAVVFGGRSSEHAISCVTAGAVMAAIDRDRYEVVPIGIARDGRWVLASDGQRL
AIEDGRLPEVDGGGTALALPFDPAARGLIAVAPGEIPASLGEVDVVLPLLHGPFGEDGTI
QGMLDLAGIRYVGAGVLASAVGMDKGFMKLVWQAQGLPVGPYVLVGDREWRRERKRKIDE
IKELGLDAGRPVFVKPARAGSSMGISRVTSEDDLEAAVEAAREHDPKVIVEAAIEGREIE
CGVLQGLDDGPAEASLPAEVRTSGDSDFYDFETKYLDGGTTMEIPPDLPEPAIEEVRRIA
VQAFEALDCEGLARVDFFRTPDGRWVLNEINTMPGFTPASAFPQMWAATGLDYPALVDRL
IRTAADRTTGLR
NT seq
1119 nt
NT seq
+upstream
nt +downstream
nt
atgtcccattccaagatccgcgtggccgtcgtgttcggcgggcgcagcagcgagcacgcg
atctcctgcgtcaccgccggagccgtgatggccgcgatcgaccgggaccgctacgaggtg
gtgccgatcggcatcgcccgcgacggccgctgggtactggcgtccgacggccagcggctc
gcgatcgaggacggccggctgcccgaggtggacggcggcggcacggcgctcgcgctgccg
ttcgaccccgccgcccgcggcctgatcgccgtcgccccgggggagatccccgcctcgctc
ggcgaggtcgacgtcgtcctgccgctgctgcacggcccgttcggggaggacggcaccatc
cagggcatgctcgacctggcgggcatccgctacgtcggtgccggggtgctggccagcgcg
gtcggcatggacaagggcttcatgaagctcgtctggcaggcgcaggggctgcccgtcggc
ccgtacgtgctggtcggcgaccgggagtggcgccgcgagcgcaagcgcaagatcgacgag
atcaaggagctcgggctggacgcgggtcgtccggtgttcgtcaagcccgcgcgggccggg
tcgagcatgggcatcagccgcgtcacctccgaggacgatctggaggcggcggtcgaggcg
gcccgcgagcacgacccgaaggtcatcgtggaggccgcgatcgagggccgcgagatcgag
tgcggcgtgctgcagggcttggacgacggcccggcggaggcgagcctgcccgccgaggtg
cggacgtccggcgacagcgacttctacgacttcgagaccaagtacctcgacggcggcacc
acgatggagatcccgccggacctgccggagccggcgatcgaggaggtccggcgcattgcc
gtccaggcgttcgaggcgctggactgcgagggcctcgcccgcgtcgacttcttccggacg
ccggacggccgctgggtcctcaacgagatcaacacgatgcccgggttcacgcccgcgtcg
gcgttcccgcagatgtgggccgcgaccggcctggactacccggccctcgtcgaccgcctg
atccggaccgccgccgaccgcaccaccggcctgcgctga
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