Actinomycetospora sp. NBC_00405: OG774_03205
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Entry
OG774_03205 CDS
T09735
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
acty
Actinomycetospora sp. NBC_00405
Pathway
acty00300
Lysine biosynthesis
acty00550
Peptidoglycan biosynthesis
acty01100
Metabolic pathways
acty01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
acty00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
OG774_03205
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
OG774_03205
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
OG774_03205
Enzymes [BR:
acty01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
OG774_03205
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Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
DAGK_cat
Motif
Other DBs
NCBI-ProteinID:
WUI62423
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Position
641478..642962
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AA seq
494 aa
AA seq
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MIELTLADVARVTGGRLHRASGDERITGSVEFDSRAVTPGGLFVALPGERVDGHDFVDAA
TAAGAVGVLAAREVDAPAVIVPPVSGISSSYVLAADADGAGAGVLAALAVLARHVVDTLV
ANTGSRGGLSVVGITGSSGKTSTKDLTAHLLEAGPDGKGSPTVAPPGSFNNELGHPWTAL
RATPETRHLVLELSARGPGHVAALCRVAPPRIGVVLNVGSAHLGEFGSREAIAQAKGELV
EALPAAQDGGVAVLGADDPVVAAMAQRTAARVVHTGRALAATVRAVDERLDDAGRATFRL
VTRAGETPVTLGLHGAHHVDNALAAAAVALEAGLDLGTVAARLATAAPRSRWRMELTERP
DGVRVLNDAYNANPESMRAALATLAAMGGRHTAVLGVMAELGDDAPQAHTELGREVARTG
VQRLVVVGGDGPVAALHEAATAGGVDSHLVPDAAAAADMISAGVAPGDVVLVKASRSAGL
ERVADALVNGRGAR
NT seq
1485 nt
NT seq
+upstream
nt +downstream
nt
gtgatcgagctgaccctcgccgacgtcgcccgcgtcaccggcgggcggctgcaccgcgcg
tcgggtgacgagcgcatcaccggctccgtggagttcgacagccgcgccgtgaccccgggc
ggcctgttcgtcgccctgcccggcgagcgggtcgacgggcacgacttcgtggacgccgcg
acggcggcgggcgccgtcggggtgctggccgcccgcgaggtggacgcgccggccgtgatc
gtgccgccggtctcggggatctccagctcctacgtgctcgccgcggacgccgacggcgcc
ggggccggggtcctcgccgcgctggccgtcctggcgcgccacgtcgtcgacaccctcgtc
gccaacacaggatctcggggcggcctctccgtcgtcggcatcacgggttcgtcgggcaag
acgtcgaccaaggacctcaccgcgcacctgctggaagccggcccggacgggaaggggagc
ccgaccgtcgccccgcccggctcgttcaacaacgagctcgggcacccctggaccgcgctg
cgcgccacgcccgagacccgccatctcgtcctcgagctctccgcccgcgggcccggccac
gtcgcggccctgtgccgggtcgcgccgccgcggatcggcgtcgtgctcaacgtcggctcg
gcccacctcggcgagttcggctcgcgggaggcgatcgcacaggccaagggcgagctggtc
gaggccctgccggcggctcaggacggcggcgtcgccgtcctcggcgccgacgacccggtg
gtggcggcgatggcgcagcgcaccgcggcacgcgtcgtccacaccgggcgggcgctcgcg
gcgacggtccgggcggtcgacgagcgcctcgacgacgccgggcgcgcgacgttccggctg
gtcacacgcgcgggcgagacgccggtgaccctcgggctgcacggcgcccaccacgtcgac
aacgccctggccgcagcggccgtcgcgctcgaggcgggcctggacctcggcaccgtcgcc
gcgcgcctcgccaccgcggcgccccgctcgcgctggcgcatggagctcaccgagcgtccc
gacggcgtccgcgtgctcaacgacgcctacaacgcgaaccccgagtcgatgcgcgccgcg
ctggcgacgctcgccgccatgggcgggcgccacaccgcggtgctcggcgtcatggccgag
ctcggcgacgacgccccgcaggcgcacacggagctcggccgcgaggtcgcccgcacgggt
gtgcagcggctcgtcgtggtcgggggcgacggcccggtggccgcgctgcacgaggccgcg
acggcggggggcgtcgactcccacctggtgcccgacgccgcggcggcggccgacatgatc
agcgccggcgtcgctccgggcgacgtcgtcctggtgaaggcctcccgctcggcggggctc
gagcgggtcgcggacgcgctggtgaacgggagaggagcccgatga
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