Actinomyces sp. 432: CWT12_03765
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Entry
CWT12_03765 CDS
T06433
Name
(GenBank) D-alanine--D-alanine ligase A
KO
K01921
D-alanine-D-alanine ligase [EC:
6.3.2.4
]
Organism
actz
Actinomyces sp. 432
Pathway
actz00470
D-Amino acid metabolism
actz00550
Peptidoglycan biosynthesis
actz01100
Metabolic pathways
actz01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
actz00001
]
09100 Metabolism
09106 Metabolism of other amino acids
00470 D-Amino acid metabolism
CWT12_03765
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
CWT12_03765
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
CWT12_03765
09180 Brite Hierarchies
09181 Protein families: metabolism
01011 Peptidoglycan biosynthesis and degradation proteins [BR:
actz01011
]
CWT12_03765
Enzymes [BR:
actz01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.4 D-alanine---D-alanine ligase
CWT12_03765
Peptidoglycan biosynthesis and degradation proteins [BR:
actz01011
]
Precursor biosynthesis
Amino acid ligase
CWT12_03765
BRITE hierarchy
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Paralog
Gene cluster
GFIT
Motif
Pfam:
Dala_Dala_lig_C
Dala_Dala_lig_N
CPSase_L_D2
ATP-grasp
ATP-grasp_4
Motif
Other DBs
NCBI-ProteinID:
QHO90631
UniProt:
A0A7L5AMK6
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All DBs
Position
924454..925689
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AA seq
411 aa
AA seq
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MSVPSAAGAVSNGVTADSSLVSSASATSASPGSRPARHARKPRVAVVFGGRSGEHTISCA
TAAGVLDAIDRDRYDVVPVGITRQGQWVLVDDDPDALRLDDARPPVEITTDGLGRGELAM
RLGGGKLTAITPAGPEVLGAVDVVLPLLHGPYGEDGTIQGMLEMLGLPYVGCGVLASAAG
MDKQVTKVLLQAAGIPTAPHVLVEPHRWRRDKDAILAQCADLARPLFVKPARAGSSLGIS
RLEDLSDLEAAIESARAVDPKVLVESGIVGREIEVAVLAGHGDDAPRVAEPGEIVMDAAH
GAGEFYDYETKYLAHDAVAMVCPARIAPAERELLMRRAAEAFIAIGGEGLTRVDFFLTPD
GEAIVNEVNTMPGFTPFSMYPYMWQVSGLPYRDLVTELIELALERPRDVNR
NT seq
1236 nt
NT seq
+upstream
nt +downstream
nt
atgtcggtccccagcgcagcaggcgcagtcagcaatggtgtaaccgcggattccagcctc
gtgagctccgcgtcggccacatcggcgagcccgggctcccggcctgcccgtcatgcgcgc
aagccgcgggtcgccgtcgtcttcggcgggcgcagcggcgagcacaccatctcctgcgct
accgccgccggcgtgctggacgccatcgaccgggaccgctacgacgtcgtgcccgtaggc
atcacccggcagggccagtgggtgctcgtggatgacgatcccgacgccctgcgcctggac
gatgcccgccccccggtggagatcaccaccgacgggctcggccgcggtgaactcgccatg
cggctgggaggcgggaagctgaccgcgatcacccccgccggccctgaggttctcggcgcc
gtcgacgtggtcctgccgctgctgcacggcccctacggtgaggacggcaccatccagggc
atgctggagatgctgggcctgccctacgtgggctgcggtgtgctcgcctccgccgccggc
atggacaagcaggtcaccaaggtcctgctgcaggccgcaggcatccccaccgcgccgcat
gtgctcgtcgagccgcaccggtggcgccgggacaaggacgccatcctcgcccagtgcgcc
gacctggcccgccccctgttcgtcaagcccgcccgcgccggatcctccctgggcatcagc
cggctggaggacctttccgacctggaggcggccatcgagtccgcccgcgcggtggacccc
aaggtgctggtcgagtccggcatcgtcggccgcgagatcgaggtcgccgtcctcgccgga
cacggcgacgacgccccccgcgtggcagagcccggcgagatcgtcatggacgccgcccac
ggcgccggggagttctacgactacgagaccaagtacctggcccatgacgccgtcgccatg
gtctgccccgcccgcatcgccccggccgagcgcgagctgcttatgcgccgtgccgcggag
gcgttcatcgccatcggtggggaggggctgacccgggtcgacttcttcctcaccccggac
ggggaggcgatcgtcaacgaggtcaacacgatgcccggcttcacgcccttctccatgtac
ccctacatgtggcaggtatccgggctgccctaccgcgacctggtcaccgagttgatagaa
ctggcgctggagcgccccagagatgtcaaccgctga
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