Acidithiobacillus caldus SM-1: Atc_2198
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Entry
Atc_2198 CDS
T01581
Name
(GenBank) Phosphoribosylformylglycinamidine synthase, synthetase subunit / Phosphoribosylformylglycinamidine synthase, glutamine amidotransferase subunit
KO
K01952
phosphoribosylformylglycinamidine synthase [EC:
6.3.5.3
]
Organism
acu
Acidithiobacillus caldus SM-1
Pathway
acu00230
Purine metabolism
acu01100
Metabolic pathways
acu01110
Biosynthesis of secondary metabolites
Module
acu_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
acu00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
Atc_2198
Enzymes [BR:
acu01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.5 Carbon-nitrogen ligases with glutamine as amido-N-donor
6.3.5.3 phosphoribosylformylglycinamidine synthase
Atc_2198
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Gene cluster
GFIT
Motif
Pfam:
GATase_5
FGAR-AT_PurM_N-like
AIRS_C
FGAR-AT_N
FGAR-AT_linker
Motif
Other DBs
NCBI-ProteinID:
AEK58846
UniProt:
F9ZR77
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Position
complement(2249705..2253580)
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AA seq
1291 aa
AA seq
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MASESLHRYQVLRGPRALSAFRCAAVLRRLRAAGLPVAGISAQFVHLVQSLGPLTAEEQE
RLEALLVYDEEFPALPDAAAREVCVVPRLGTISPWSTKATEIAHSCGLLSVVRIERGRAW
FLQMEGDAHAPMALDAALVLLHDPMTESVLPDWNQPEQIFQHPAPRPLQRIPLHRDGMAA
LQAANARLGLALNTAEMEYLAQIFAGRAEDPSDAEIMMFAQANSEHCRHKIFNAEFVIDG
VAAEQSLFAMIRETHRLHPKGTLSAYKDNAAVMEAAAAGTYFHAGTDGVYTEQSEAGAIL
MKVETHNHPTAISPFPGAATGSGGEIRDEGATGRGGKPKMGLSGFSVSHLRIPGFTHHWE
RDYGRPARIRSSLDILLEGPIGAAAFNNEFGRAATAGYLRVFEADFGGLHWGYHKPIMLA
GGLGQIRPSLIHKESLPIGAKILVIGGPAMLIGLGGGAASSQASGSSSEALDFASVQRGN
PEMQRRAQEVIERCIAMGKDSPILSIHDVGAGGLANAIPELLHDGGRGGYLQLRLVPNED
PAMSPMEIWCNEAQERYVLAVAPKHLPTFLDLCARERCPVAVLGEATKAQELRVDDHFFA
NTPIRMDLGALLACPPRMRRETARCAREGSELSLYGLTLSAAARAVLAHPTVASKEFLIT
IADRSVGGLIVRDPMVGPWQVPVADCAVSVADFRSRFGEAMAVGERAPVALLDGPASGRL
AVAEALTNLFAADVRELGDVKLSANWMAAVNEPGEDAKLFDTVRAVALELCPQLNLSIPV
GKDSLSMQTSWTEGGQDKKVVAPLSLVVTAFAPVGDVEATWTPELQAEADTELWLMELGR
GRLGASILAEILGEVGREPADLDDPRKLRGAFDCLRRWRAEGLVLAYHDRSDGGLWATLC
EMSFASRLGIRAHLPEHADAWAWLFAEEPGFVVQVRQRDGQRLRAIAEELGLGRQLQHIG
AVLRESWELQILAANTPVLRESAADLLKLWAEPSYRMQALRDDPDCAAEAFAEVATIQPP
LFSTGVRSGQRAPDLRIGTRPRVAILREEGVNGHLEMAAAFHRAGFEAVDVHMSDLLAGR
ARITDFPLFAACGGFSYGDVLGAGAGWAKSIRFHPELRRQFADFFADSGRLALGVCNGCQ
MLAQLRDLIPGAEHWPVFRRNRSEQFEARLAMVEVLDSPSPFFAGLAGMQAPIVVSHGEG
RAEFAPGARPEEQIVLRYVDAHGRPAQHYPANPNGSDGAVTGLCNADGRVTILMPHPERT
QRRLNMSWCPDEWPRETPWMELFHNAHRALR
NT seq
3876 nt
NT seq
+upstream
nt +downstream
nt
atggcctcggaatccttgcaccgctaccaggtcttacgggggccccgcgcgctgtcggcc
ttccgctgcgcagcggtcctgcggcgcctgcgcgcggcaggtctacccgtcgccgggatc
tcggctcagtttgtccacctcgtgcagagcctgggccccctgactgcggaggagcaggaa
cgactcgaggccttgctggtctacgacgaggagttcccggccctgcccgatgccgctgcc
cgcgaggtctgcgtcgtaccccgtctcggaaccatttccccctggtccacgaaggcgacg
gaaattgcccattcctgtggcctgttgagtgtcgtgcgcatcgagcgtggccgcgcctgg
ttcctgcagatggaaggggatgcccacgcgccaatggcgttggatgcagcgctggtcctg
ctgcatgaccccatgaccgaatcggttttgcccgactggaaccagcctgaacagatcttc
cagcatccggcgccgaggcccttgcagcgcattccactgcaccgcgacggcatggcggcg
ttgcaggcggccaatgcgcgcctcggcctggccctcaatacggcggagatggagtacctg
gcgcagatctttgccgggcgtgcggaggaccccagcgacgccgagatcatgatgtttgcc
caggcgaattccgagcattgccgccacaagatcttcaatgccgaattcgtcatcgatggg
gtcgctgctgagcaaagtctcttcgccatgatccgggagacccaccgcctacaccccaag
ggaaccttgtcggcctacaaggacaatgccgcggtgatggaagcggccgccgctggcacc
tactttcacgccggtaccgatggggtctacacggaacagagcgaggccggtgccatcctg
atgaaggtcgaaacccacaaccaccccacggccatttcgccttttcccggtgccgccacg
ggcagcggcggcgagatccgcgacgagggagccaccgggcgtgggggcaagcccaagatg
gggctctcgggtttttccgtatcgcatctacgcatcccgggtttcacacaccactgggaa
agagactacgggcgaccggcgcggattcgctccagcctggatatcctgctggaaggcccc
attggcgccgccgccttcaacaacgaattcggccgcgccgccacggccggatatctgcgc
gtgttcgaggcggatttcggcggcctgcactggggttatcacaaacccatcatgctcgcc
gggggtcttggacagatccgtcccagcctgatccacaaggaatccttgcccattggcgcc
aagatcctggtcatcggtggaccggccatgctcatcggtctgggtggcggtgccgcttcc
agtcaggccagtggcagcagttccgaggccctggactttgcctcggtacagcggggaaac
ccggaaatgcagcggcgtgcccaggaggtcatcgagcgttgcattgccatgggcaaggat
tcccccattctgtccatccacgatgtcggtgctggcggccttgccaatgccattccggag
ctgctgcacgatggcgggcgcggcggttacctgcagttgcgactggtgcccaacgaggac
cccgccatgtcgcccatggaaatctggtgtaatgaggctcaggaacgctacgttctggcc
gtggcgccgaagcacttgcccacgtttctcgacctctgcgcgcgcgagcgctgcccggtg
gcggtgctgggtgaggccaccaaggcccaggaactgcgggtggacgaccatttttttgcc
aacacgcccatccgcatggatctgggcgccttgctggcctgccccccgcgcatgcgccgc
gagaccgcacgatgtgcgcgcgagggaagcgaactcagcctgtacggcctgaccctgagt
gccgccgcgcgtgcggtgctggcgcatccgacggtggcaagcaaggagtttctcatcacc
attgctgatcgcagtgtcggtgggcttatcgtccgtgatcccatggtggggccatggcag
gtaccggtggccgactgcgcggtctccgtcgccgattttcgctcccggtttggcgaggcc
atggccgtgggggagcgggcgcccgttgccctgctggatggtccggccagcggccgtctg
gcggtggccgaggccctcaccaacctttttgccgccgatgttcgcgagcttggggatgtg
aagctctcggccaactggatggcggcggtgaacgagccgggagaggatgccaagctcttt
gacaccgtacgtgccgtggctctggaactctgcccgcagctgaatctcagcattcccgtg
ggcaaggactccctgtccatgcagacgagctggacggagggcgggcaagacaagaaggtg
gtggcccccctgagtctggtggtcaccgccttcgcgccggtgggggacgtcgaggcgacc
tggaccccggaactgcaggccgaggcggatacggaactctggctcatggaactgggacgc
gggcgcctgggggccagcattctcgccgagatcctgggcgaggtggggcgtgagcccgcc
gacctggacgatccgcgaaagctgcgaggggcctttgattgcctgcgccgctggcgtgcc
gagggactggtcctggcctatcacgaccggagcgacggcggactctgggcgaccctctgc
gagatgtccttcgccagtcgcctgggtatacgtgcccatcttccggagcatgccgacgcc
tgggcctggctttttgccgaagagcccggctttgtggtgcaggtgcgtcaacgcgatgga
cagcgtctgcgtgccattgccgaggaacttggcctcgggcgtcaacttcagcatatcggt
gcggtactgcgcgagtcctgggagttgcagatcctggccgcgaacacgcccgtgcttcgc
gaatcggcagcggatttgctgaagctttgggccgaacccagctatcgtatgcaggccctg
cgtgacgatcccgattgtgctgctgaggcctttgcggaagtggcgaccatccagccgccg
cttttttccactggagtgcgcagtggccagcgggccccggacctacgaatcggcacgcgg
ccacgggtggccatcctgcgggaggaaggcgtcaacggccatttggagatggcggcggcc
ttccaccgcgccggtttcgaggccgtcgacgtgcacatgagcgatctcctcgccggaagg
gcgcgcatcacggacttcccgctttttgccgcctgtggcgggttctcctacggagacgtg
ctcggggctggggcaggctgggccaagtccatccgttttcacccggaattgcgtcgccag
tttgccgacttctttgccgactccgggcgcctcgccctgggggtgtgcaacggctgccag
atgctcgcgcagctgcgcgacctcattcccggcgccgagcattggcccgtgtttcggcgt
aatcgttcggagcagttcgaggcccgtcttgccatggtggaggtgctggattcgccctcg
cccttctttgccggtcttgcgggcatgcaggcacccatcgtcgtctcccacggcgaggga
cgggccgagtttgcgccgggggcgcggccggaagagcagatcgtactgcgctacgtcgac
gcccatggtcgtcctgcccagcactatcccgccaatcccaacggttcagacggtgccgtc
acgggcctctgcaatgccgatggacgagtgaccatcctcatgccgcatccggagcgtact
cagcgtcgcctcaacatgagctggtgtccggacgagtggccccgtgagaccccgtggatg
gagcttttccacaacgcacaccgggcgctgcgttag
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