Athene cunicularia (burrowing owl): 113477872 Help Entry 113477872         CDS       T05777                                  Symbol SYNE1 Name (RefSeq) nesprin-1   KO K19326   nesprin-1 Organism acun  Athene cunicularia (burrowing owl) Pathway acun04820   Cytoskeleton in muscle cells Brite KEGG Orthology (KO) [BR:acun00001]  09140 Cellular Processes   09142 Cell motility    04820 Cytoskeleton in muscle cells     113477872 (SYNE1)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    03036 Chromosome and associated proteins [BR:acun03036]     113477872 (SYNE1) Chromosome and associated proteins [BR:acun03036]  Eukaryotic type   Centrosome formation proteins    LINC complex     113477872 (SYNE1) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Spectrin Spectrin_SYNE1 SYNE1 CH KASH GM_CSF Motif Other DBs NCBI-GeneID:  113477872 NCBI-ProteinID:  XP_026700353 LinkDB All DBs Position 3 AA seq 8741 aa AA seqDB search MASSRLVARSRDIANVMQRLQDEQESVQKRTFTKWINTHLAKRNPPMLVNDLFEDIKDGV MLIALLEVLSGQKLPCEQGRQLKRIHWVANIGTALKFLEGRRSIYRGSPIKLVNINSTDI ADGRPSIVLGLVWTIILYFQIEELTSNLPQLQSLSSSASSVESVVSSETASPPSKRKVVT KVQGSARKALLKWIQYTAAKQVGIEIKDFGQSWRSGVAFHSVIHAIRPDLVDMEKVRGRS NRENLEEAFTLAEAELGIPRLLDPEDVDVDKPDEKSVMTYVAQFLKYYPDPHHTVTDVQE NDELQAIPTFVISFMKFKKEDRLMLRDLKVWAEQFERDLTRAQMAETSLQEKYQSFKHFR VQYEVKRKPIELVTQSLRKDGKLSLDQAIVKQAWDRVSSRLLDWHIHLDKSLPAPLGTIG AWLYRAEAALREEITVHQAHEETANTIHRKLEQHKVDLHTFILCIIIPCFQRIQVGYHIH SCKIEQAILKPFDAEFNFVVSSSELHLLKMEFLELKYRLLSLLVLAESKLKSWIIKYGRR ESVELLLQNYISVIENSKFFEQYEVTYQILKRAAEMYAKANGSVEEVENVMKFMNETTAQ WRNLSVEVRSVRSMLEEVIANWDRYSSTVAGLQAWLEDAEKMLNEPEHSKKDFFRHLPHW IQQHTAMNDAGNFLIETCDETISRDLKQQLLLLNGRWRELFMQVKQYARADELDKMKKEY LDGVAHLTAFIDGSNRKLSVAVEVSFLDVKMFIQDLENIKQKLPAMESQYKMIARTAQLV TKEVSQEEVNEMLGTLTRIKEQLSKVKEYSCALLYECQRLLSPLEELEKQITHFYESLEK VNEIISILDPEAQPTTVLKQKAQDLVAYQENCKKDLSLIERNSQSILQCVASSEVLQHFH QSTFQKKVTQVQITFQNMVRKAGDWRKNIEANSRLMKKFEESRAELEKVIQIANCCLKEK GNPEELLRKHSEFFNQLDQRVLNAFLKACDELTDILPEQEQHNLQDAVRKLHRQWKDLQT EAPYHLIHLKVEVQKSKFLVTVEECKAELVRQNKVLSREGNEKMIEEHMLFFGDKGSYHL CEKRLQRIEELCQKLPVSDPVRATLESSQRILKDLKSQIDSTYVKLTERSDTWKSYKNRF SELANWILSTEGELKKIKESVNDTAKYKQFKASVGEIRKHINKQGENHSWLKARLPVLTA ACPDLEAKRTEDELCNLSSEFKGLLDLLAEVEKNLGTVGDCVQYKEEVKSAIEELINNSK EAQAEAEKILNTESLLQAQQLLLHHQQRTRRLRAKRQGVQQQISQAKQLQVEGGLPRIMQ EDLLKLEGTLENMQQTMEKREEQLQVTINKWEQFERDKETVVKYLKQASSALERILNFSS LESLSSELDQTKELSKQTEAMAVQAENLVKNSSEIQLGSKNKQSLQQQAKSIQEQVKKVE VTLEEDIKSMEMVKNKWDHFGNNFEALSIWIAEQEKELETLETSSSPLDIQISQIKVINK EIDGKITAISKLEEEAESFSQFVTSGECAHIKAKLTQVKRYWEELRDHAQRLEGTITGNA SAQQKYEESLKQVQQAVSEFEAKLAEPPTPCSSSSATYAALQDCTDLCHTLEKLNNTLAS LSACARKVAKKEKAAQEVTALQQKYEKVLANAKEKQTLLETLLAQWQKQEKELSAFLTWL DGCEATARPPEQYVSADRVKLEGELQSLQNLRADIESHASIYASLIQLNESLFPTASKQH VKTITEKFEELDERWKALPKTVDKRINFLQSLVAEHEQFDELLLRFSDWIKQFLAELQAT SEINTADQQLAASHNKNHSREVESKKQQLQSLKEHVDKLCSFSCPEDQQTLQGKTEDCFQ IFQEASQITSQRQEALDHLRVFLEHHSVASGVLHQLRQAVEKTGNMDKAKSELLEKELSN VIQDLNKLESVAISLDGSLTKAQYHLKHSISEQRTSCRALVDNLCLELEAVQNLLGTKQS EAEALGALQRSFMERKEQLLKSIEDIEEKADKEALKEATLQALQQRLRIFTQLDEELNSH QHELQWLRDRGKQIAQKDFTLAPEIDKEINCLESLWEDTKKVIHEKKEQSCILIDLMKEY QTLKSTVMKVIDGADSASVIKSIWKDREDVRRILSRHEAAKNDLSDKQKDLDTFTNKGKH LLTELKRVHNCDSTAVKTDMNSTVDKWLDVSERIENNIDQLSVNVALWDDILKTGDEMDG WCNKCISQLNEGISNLSNSQRMEVLLKDFQSEVKDKELKLDQLSSKISDLKELTHSQDPP ADLQFIESDLRQKLEHAKEMSETAKETLKDFCTQKMQLQKFIDQMTDWLTKVEETLLSCA RNLNPEALNKVKETQKDLQLQQSSIDSTRENLNSLCRKYHSVELETLGGTVTSLIKNYEA VNLLCSRTQASMQESLEKHFLHSMQEFQEWFSGVKAAVKESSDRSGDSSVIEAKLHDLQT VMDSVSEGQNKLDAACKEGESLYACLPKPVVSHIQDQIVRSNQNFQEFLNQCLNDKKALE ACASHLGNFEDQQKKLGLWIRDMEERITTEALGESKQLIPEKKKEVQKVEKFLEELLSSR ESFDKLSQMAQTLNEEGHGAGREVRLASQHLTNYQNMVKTIKEKLRTCQLALQEHLTLEE ALQSMWSWVKEVQDKLASSESTVGSKATLERRLTQIQEILLLKGDGEVKLNMAIGKGEQA LRSTNEEGQKVIQTELQTLKDVWNDIISTSMNWQSCLESVIGQWNEYLERKNQLEQWLEK LDHKVEQPVEPQIGLKEKFAQLDHFQAVVSEIEDHSGDLQQLIEKAVELYEKTEDDSFGE AAQEELKTQFNDITTVAKEKMRKVEDIVKDHLLYLDAVHEFTDWLHSAKEELHRWSDSSG DTSTIQKKLDKINGELLAAWSQGLAPRDSRHTDSEVLESWRKEKETLDALLKSEHMTEEI KTQLNDLCRFSRDLSTHSSKVSGLIKEYNSLCLQASKGCQSKEQILQQRFRTAFRDFQQW LVNAKVTTAKCFDVPQNISEATASLQKIQEFLSESETGQQKLNLLASKGELLCSVLPNEK AKVIQDKSATAKEDWKNFITTLHQKESALENLKIQMKDFEATAEPLQEWLTTTEKMVQGS SSRLHDLPSKRREQQKLQSVLEEISCHEHQLNRLKEKAQQLGEEQADSKSFMRRVSQLSS QYLTLSNLTKEKVSRMDRVVAEHQQFSHSVKDLQDWVADAVHMLDSYCHPTADKSVLDSR MLKLEGLLAVKQEKEIQMKMVLSRGESVLQNTSLEGVPVIERQLQTLKDSWASLLSACIQ CKSQLEGALSKWTSYQDDVRQFSSWMDKVEASMNASERQYAELREKTAALSKAKLLSEEV LSHSSLLETIEVKGSGMAEHYVTQLELQDLQERYRFLKDRTKEAVTKAEELLNLHQEYQR NLKAFEVWLEKEQEKLDCLSHLDGDAQKQEAMLRDLQELQVHCVEGQALLNAAVHAREEV IPWGIPQIEDRALESLRQDWQVYQHRLSEARSQLNATVSRLRLMEKKFQKVNDWLTDLEE KVAIRTGRQSGRATKEMQLQQMKKWHEEITIYKDDVEEVGVLAQQILEECLTASRMGSQA TQLTSRYQTLLLHVLEQIKFLEEEIRCMDESELAFSAYTNWYGATNKNFRNVITKFDVVD KTAMEKKVQKLELLLSDMDIGHSLLKSAREKGERAIKYMEENEVDQLRKEIGDHVEQLEE LAGSIRKEHMTSEKCLQLAKEFSDKYKAQTQWVMEYQAMLHAPAEPKSELYEKKAQLSKY KSIQQTVLSHEPSIKSVIEKGEALFDLVNDMNLKNNIQDLQSTYQELCSTTKAYVETLEV RVKEHEDYNSDLQEGEKWLLHMSSRLVSPDLMESNSLEIITQQLANHKAIMEEIAGFEDR LNSLKSKGDYLINQCTEHLQAKFKQNIQSHLQGTKDSYSAICSTAQRVYQSLEHELQKHV NHQDTLQQCQTWLSTVQSELKPTTWPPFSLADAVKQVKHFRALQEQANTYLDLLCSMCDL SDATVKSTATDVQQTKQTIEQQIMHSQYLAQGWEEIKQMKAELWIYFQDADQQLQNLKRR RAELELNIAQNMVLQVKEFSQKLQSKQSALTSVTEKMNKLTQGQESPEHKEIGELSNQWL DLCLQAHSLLIQREEDLQRTGDYHDRMNVVEVFLEKLTKEWDNLARSDAESTNVHLEALQ KLALALEERRFALEDMKDQKQKMIEHLNLDDKELIKEQYGHFEQRWTQLEDLVKRKIQVS VSTLEELSLVHSKFQELMEWAEEQQPSISEALKQSPPPDLAQSLLMDHLTICSELEAKQL VLKVLVKDADRVMTNLGLNERQELQKALSDAQHHVECLSDLVGQRRKHLNKALSEKTQFL MAVFQATNQIHQHEKKVTLPEHICLLPEDVTKQIRTCKNAQANLKAYQNEITGLWAQGRD LMKEATEQEKSEVLGKLQELQNVYDSVLQKCNQRLLELEKNMVSRKYFKEDLDKACHWLK QADIVTFPEVNVMNSNSELYNQLAKYQQILEQSPEYENLLLALQRDGQEILPSLNEVDHS YLDEKLNILPQQFSIVTALAKEKLYKIQEAIYARKEYASLIELTIKALNELEDQSINMDK APATVSAKEAVSLQQAYRDLLGEVVSLGAAVDELNQKKEAFRSTGQPWEPDEMLKLVTLY HKLKRQIEQKINLLEDMIEACQEHENMCMQFEAQLEAVKKEQIKVNEETLPIEEKLKIYH SLVGSLQDSGSLLKRITEHLEALSPQLDSSACETTDHQVQSWQEKLKSLHAAISDTVMDC ENRLVQSIDFQTEICRSLDWLRWVKTELNGTLSLDLKLQSIQEEIRKVQIHQEEVQSSLR IMNALSNKEKERYMKAKELIPADLENTLAELTELDGEVQEAIHTRQATLNKLYSLCQRYY QVMQIANDWHEDAQEFLRLARNGLDVENSEENLRNHIEFFSTESQFGNHLKELQGLVSEM EPFIQDTAREQLLQNVAALEEKAKETKQEAKAQQEQLQRCASEWQEYQTARQKVIEVMNE AEKKLSDFSVAKAASSHAAEEKLQTHKTLVSVVNSFHEKITALEEKALQLEKVSNDASKA TISRSMTTVWQRWTRLRNVAQEQEKILEDAGQEWKDFNDKIQKATIAIDQLQGRLPESSV EKASKAELLELLDYHSTFLLEVEHQLSSLGLLKQHVVSMLQDVEIKPLSQEELPVMQEIK AMQDRCHNMQQKVKKGVKMVKQELKEREEVEGEINIVKSWIQETKEYLLSPDIEVDTQLQ ELQSLLGEVTTHRQAVEKMAEQQQNKYLGLYTILPSELSLHLAEVGLALVTIQDQIQTKE RETQQIKTLNQEFGQKIQGIANELNAILSKLKKKTNDIAQAKLEQKILGEELDSCNIKLL ELDASVQDFAEQNVPLAKQLANRIGKLTVLHQQTVRQAEYRAAKLSQAASHLEEYNEMLE FILKWTEKANILVHGSIIWNSSSQLRDQFKAYQTMLDESGEIHGDLEAMSERIEYLASVY CTEGMSQQVLELGRRTEELQQVIKVRLPNLQDAAKDMKKFEVELRVLQAALEQAQATLTS PELGHLSLKEQLSHRQHLLSEMESLKPKVQAVQICQSALRIPEEVVTGLPMCHSALRLQE EASRLQHTAIQQCNIMQEAVVQYEQYEQEMKHLHQMIESAHREIQDKPIATSNIQELQVQ ISHNEELAQKIKGYQEQIASLNSKCKMLTMKAKHATMLLTVTEVEGLSEGMEELDSDLLP AHPTHPSVVMMTAGRCHTLLSPVTEESGEEGTNSEISSPPACRSPSPVANTDASVNQDIA YYQALSAEQLQTEAAKIQPSTSATQEFYEPGLESAASAKLDDLQRSWETLKNVISEKQRT LYEALERQQKYQDTLQSISTKMETTEIKLNESLEPAKSPESQMAEHQALMDEILMLQEEI TELQTSLAQELVSEPLDAEAGDQLALQSTLTVLAERMATIRMKASGKRQLLEEKLNEQLE EQRQEQALQRYRCEADELDHWLLNTRATLNSALVTAEEPMDMEAQLVDCQNMLVEIEQKV IALSELSVHNENLLMEGKAHTKDEAEQLAMKLRTLKSSLLELQRVLHDKQTNIRGSLQEK EESDLDFVSSQSPSVQEWLAQARTTRSQQQQNTLQQQKELEQELEEQKNLLRSVACRGEE ILTQQGAPEGLCISDKPDILSEELGLEGEKPSSEEQMKVKWESLNREFNTKQRLLQKALE QEQLQLYSRPNRLISGMPLYKEEGQDEDKSSVSPVLDELNQAFEDVSSEAGRVEESLHLE EKLYDGVIATSLWLDGVEEQVFVATSLLPEEQRETYLCKQESLAKEIKDIMEEMDKNKNL FAKIFPENGGNRDIIEDTLDCLLRRLTLLESVVNQRCHQMKGQLQQIVTFKNDLKLLFTS VADNKYLVLQKLAEAVERPETEQMQVILQAEESLKELDAGINELKKRVDKLEIDQSSVQE LSKIQDKYDELMMIIGSRRSDLNQNLALKRQYERALQDLTDLVETGQEKMAGDQKIIVAS KEEVQLLLDKHKEYFQGLESHMILTETLFRKMSSFALLKKTQSHSELMTQASAVLKLAHK RGVELEYILETWMHLDEDYQELTRQLESVEDNIPTVGLVEETEERLTDRITLFQHLRSNL NEYQPKLYQVLDDGKRLLFSISCSDLESQLNQLGEQWLSNTSKVTKELHRLETILKHWTR YQSESNELAHWLQSAKERLEFWSQQSLTVPQELETVRDHLNSFLEFSKEVDAKSSQKSSV LSTGNQLLRLKKVDTAALRAGLSHIDSQWTDLLTQIPAVQEKLHQLQMDKIPSRHAITEV MSWISLMENVIQQDEENIKNVVGQKVIQDYVQKYKGFKIDLNCKQLTVDFVNQSVLQISS QDVESKRSDKTDFAEQLGAMNRRWQILQGLITEKIQLLESLQESWTEYENNVQCLKTWFE TQEKKLKQQQKIGDQASVQNALKDCQELEELIRTKEKEVENVEQSGLSLVQNKNEEVSSA VMNTLQEINHSWANLDHMVSQLKILLQSVLDQWSIYKEAYEELNGYLTEARYSLSRFYLL TGSLEAVKIQVDNLQSLQDELEKQENSLQKFGSVTNQLLKECHPPVTETLTNTLKEVNMR WNNLLQEIAERLRASKGLLQLWQRYKDCYQQCSSIVRQREDQTNELLKTATSKDIADDEV TTWIQDCNDVLTDLKTAQDTLIVLQELGEELKSQVEPSAAAAIQSDHLSLSQNLSTLEQA LHKQQVVLQAGVLDYQTFAKNLQVLEAWITEAEEILKGQDPSHSSDLSTIQSRMEELKSQ MLKFSSMAPDLDRLNELGYRLPLNDKEIKRMQNLNRHWSLISSQTTERFSKLQSFMLQHQ TFLEKCETWMDLLVQTEQKLAAEISGNYQSLLEQQRAHELFQAEMFSRQQILHSIISDGQ HLLEQGQVDDRDEFNLKLTLLSNQWQGVIRRAQQRRGIIDSQIHQWQRYREMAEKLRKWL VEISCQLVSGLGNVPIPLQQARALLDEVQLKEKVLLRQQGSYILTVEAGKQLLLSADSEA EAALQTELTEIQERWKIASTQLEQQKKQLALLLKDWEESEKGIGDSLEKLRSFKKKLSQP LPEHHDELHAEQIRCKELENAVEGWTDDLAHLSLLKETLSIYISAEDISILSERIELLHR QWEELCHQVSLRRQQVSERLNEWAVFSEKNKELCEWLTQMESKVSQNGDILIEEMIEKLK KDYQEEIAVAQKNKIQLQQMGERLAKASHESKASEIEYKLGKINDRWQHLLDLIAARVKK LKETLVAVQQLDKNMSSLRSWLAHIESELSKPIVYETCDSEEIQRKLNDQQELQRDIEKH STGVASVLNLCEVLLHDCDACATEAECDSIQQATRNLDRRWRNICAMSMERRLKIEETWR LWQKFLDDYSRFEEWLKVSERTAAFPSSSGVLYTIAKEELKKFEAFQRQVHESLTQLELI NKQYRRLARENRTDSDCSLKQMVHEGNQRWDNLQKRVTSILRRLKHFIGQREEFETARDS ILVWLTEMDLQLTNIEHFSECDVQAKIKQLKAFQQEISLNNNKIEQIIVQGEQLIEKSEP IDAAVIEEELDELRRYCQEVFGRVERYHKKLIRLPLTDDEHDLSDREVDLDESADLSDIH WHDKSADSILSPHPSSNLSLPLSQPVRSERSGRDTPASVDSIPLEWDHDYDLSRDLETAV SQALHSEEEDGGQEKDFYLRGAAGIADVEIPETLEAYVTLTENTLKNLSGEPGALEAHIR QLDKALDTSRFQIQQTENIIRSKTPTGPELDSSYKGYMKLLGECSGSIDSVKRLGYKLKE EEEKLSGLINLNSTETQTAGVIDRWELIQAQALSKELRMKQNLQQWQQFNSDLNSVWAWL GETEEELEKLHHLDLSTDIQTIELRIKKLKELQKAIDNRKAIILSINLCSSEFTQSDSEE SKKLQERLSQMNVRWDHVCSMIEEWRCSLQDALMQCQDFHEMSHGLLLWLENIDRRKNEI VPINPNLDPEMLQDHHRLLMQIRRELLESQLKVASLQDMSCQLLVNAEGKDCLEAKEKVH VIGNRLKLLLKDVIRHIKDLEKILDISSSQLELSSWSSADELDTSGSVSPVSGRSTPSRQ RTPRGKCSLSQPGPSVSSPHSRFTRGGSGSSPSEAGPAWRHPSFFLRVLRAALPLQLLLL LLIGLACLVPMTEEDYSCTMANNFARSFHPMLKYMNGPPPL NT seq 26226 nt NT seq  +upstreamnt  +downstreamnt atggcctcatcccgactagtggcaagatctagagatattgccaatgtcatgcaaaggctt caagatgagcaagagtctgtgcagaaaaggactttcacaaaatggatcaatactcatctg gctaagcgcaatcctcccatgctggtgaatgatctgtttgaagatatcaaagatggggta atgttaattgcccttttggaggttctttcaggacagaagctgccttgtgagcagggacgt cagctgaagagaattcactgggttgccaacattggcacagctcttaagtttctagaagga agacggtccatatacagaggatctccgattaagcttgtcaacataaactcaactgatatt gctgatggcaggccttctattgtgcttggcttggtgtggaccataattttgtatttccag attgaagagcttaccagcaacctcccacagctgcagtcgttgtctagcagtgcttcttct gtggaaagtgttgtcagttcagaaactgcaagtcccccaagcaaacggaaggtggtaacc aaggtccagggaagtgccaggaaggctttgttaaaatggattcagtacacagcagcgaag caagttggaattgaaatcaaagattttggacaaagttggaggagtggtgttgcatttcat tccgttattcatgctatccgtccagatttagtggacatggagaaagtgaggggaaggtca aacagagaaaacctggaagaagccttcacacttgcagaagcagaactaggaattccaagg ctccttgatccagaagacgtggatgttgacaagccagatgaaaagtctgtcatgacttat gtagcccagtttttgaagtactatcctgatcctcatcatacagtgactgatgtgcaggag aatgatgaacttcaagcaatcccaacttttgtcatttcttttatgaaatttaagaaggaa gacagactgatgctgagagacctaaaagtgtgggcagaacaatttgaaagagacttgacc cgagcacagatggcagaaacaagcttacaggagaaataccagtcatttaagcatttcaga gtacaatatgaggtaaaaaggaaaccgattgaacttgtaacccagtcattaaggaaagat ggtaaattatcacttgatcaagctatcgtgaagcaagcatgggacagagtttcttccagg ctacttgactggcacatacaccttgataaatctcttcctgcacctttgggtaccataggt gcttggctttatagagcagaggctgctctgagagaagaaattactgttcaccaagctcat gaggaaacagcgaatacaatacaccggaagcttgaacaacataaggtagatctacataca ttcattctgtgcattataattccttgtttccaaagaatacaggtcgggtaccacattcat tcgtgtaagatagagcaagcgatcctgaaaccttttgatgctgagtttaattttgttgtc tcttcatctgagctccatctgttgaagatggagtttctggaactgaagtaccgtctactg tcactcttagtccttgcagaatcaaagttaaaatcatggattatcaaatatggaaggcga gaatcagtggaactacttcttcaaaattatatttctgttattgaaaatagtaagttcttt gagcagtatgaagttacttaccagatcttgaaaagagcagctgaaatgtatgccaaagca aatggctcagtggaagaagttgagaatgtaatgaaattcatgaatgaaacaacagcgcag tggagaaacctgtcggtagaggtgagaagtgtaagaagcatgttggaagaagtaattgca aattgggacagatatagcagcactgtggcaggtctacaagcttggctggaagatgctgaa aaaatgctgaatgagcctgaacattctaaaaaggatttcttccggcacttacctcactgg atccaacagcacacagccatgaatgatgctggtaattttctgattgaaacgtgtgatgag accatttccagagacctaaaacagcagcttctgttactaaatggaagatggagagaattg tttatgcaagttaaacagtatgctcgagcagatgaactggacaaaatgaagaaagaatac ttggatggtgttgcccatttgacagcttttattgatggaagcaataggaaactttcagtc gctgtagaagtatccttccttgatgtcaaaatgttcatacaagatttggaaaatattaag cagaaattgcctgcaatggaatctcagtacaaaatgattgcaagaacagcacaacttgtt acaaaagaagtttcccaagaggaggtgaatgaaatgcttggaactctgacaagaatcaaa gagcagctgagcaaggttaaggagtattcctgtgctttgctgtatgaatgccagcgtctg ctgtctccactggaagaactggagaaacagatcacacacttttatgaatctcttgaaaaa gttaatgagataatttctatcctggatcctgaagcacaacctacaactgttcttaaacaa aaagcccaagatctggtagcttaccaagaaaactgcaagaaagatttgtccttgattgag agaaatagtcagagtatcctgcagtgtgtggcttcgagtgaagtgttacagcatttccat cagtcaacatttcagaagaaagttacacaagttcagattacttttcagaatatggtcagg aaagctggtgactggagaaaaaacatagaagcaaatagccgtttgatgaagaaatttgag gagtctagagcagaactggagaaagtaatacagattgccaattgttgcttaaaagaaaaa ggaaatcctgaagaacttctcaggaaacatagcgaattctttaaccagttggatcagaga gtcctaaatgcctttctgaaagcatgcgatgaacttactgacatcctcccagaacaagaa caacacaacctgcaggatgctgtaagaaaactccacaggcagtggaaggatcttcaaaca gaggccccatatcatttgatccacttgaaggttgaagtacagaagagcaagttcctggtc acagtggaggagtgcaaagctgaacttgttcgacagaacaaggtcttatcaagagaaggc aatgaaaagatgatcgaggaacacatgttgttcttcggtgacaagggatcttaccatctc tgtgaaaaaaggctacaacggattgaagaactgtgccaaaaactaccagtttctgatcca gtgagggctacattggaaagcagccaacgaatcctgaaggacctcaaatcccagatagac agcacatacgtaaagttaacagagcgctcagacacctggaagagctacaaaaacagattt tctgaattggcaaattggattttgtcaacagaaggagagctaaagaagataaaggaaagt gttaatgatactgccaaatacaagcaatttaaagcatctgtgggggaaattaggaagcat attaacaagcaaggagaaaatcacagctggctgaaagctaggcttcctgttttgactgca gcgtgtcctgatttggaggccaaaaggacagaggatgagctttgtaacctttccagtgaa ttcaagggactcctagatttactggctgaggttgaaaagaatttaggcactgttggagac tgtgtccagtacaaggaagaagttaaaagtgcaattgaagagttaatcaacaactctaaa gaagcccaagcagaggctgaaaagatcctgaacacagaaagtttgttacaagctcagcaa ctactacttcatcatcagcaaaggacaaggagactccgtgcaaagaggcaaggtgtgcaa cagcagatttcccaagctaaacagttacaggttgaaggtggactacccagaataatgcaa gaagatttactaaagttggaaggaacattggaaaacatgcagcagactatggagaaacgt gaagagcaactgcaggtcacaataaataaatgggagcagtttgaaagggacaaagaaaca gtagtaaaatacctcaagcaagcaagctctgcacttgaacgtatcttaaactttagcagt ttagagagcctctcttcagaactggatcagacaaaggaactttctaaacagactgaagca atggcagtgcaggctgagaatttggtgaagaattcttctgagatacagcttggttcaaag aacaagcagtcccttcagcagcaggcaaaatcaatccaagaacaagtgaaaaaagtggaa gttactcttgaagaagatattaaaagcatggaaatggtgaaaaacaagtgggatcatttt ggcaataattttgaagctctgtccatctggatagctgaacaagaaaaagaactggaaact ttggaaacatcatcatctcctttggacatacagatcagccaaatcaaggttattaataaa gaaatagatggtaaaataactgcaatctccaaactagaagaggaagctgagtctttttcc cagtttgttacctctggagaatgtgcacatattaaagccaaactgactcaggtcaaaagg tattgggaagagctaagagatcatgcgcagagactggaaggaacaatcacagggaatgca tcagcacagcagaaatatgaagaaagccttaaacaggtgcagcaggcagtgtctgaattt gaagctaagctagctgagcctcccacaccttgctcttcatcctctgcaacatacgcagcc cttcaagattgcacggacctttgtcatactctagaaaagctgaacaacactctggcctct ctctcagcctgtgcccgaaaggtggccaagaaagaaaaagctgctcaggaggttactgca ttacagcagaaatacgaaaaggtgctagcaaatgctaaagagaaacagaccttattagag actcttctggctcagtggcagaagcaggagaaggagctgtccgcctttctgacctggttg gatgggtgtgaagctacagccaggcctccagagcagtatgtttctgctgacagagttaaa ctggaaggtgaactgcagtcactgcagaatttgcgagcagacattgagtcccatgcttcc atctatgcaagcctaatacagttaaatgagtcactgttcccaacagcttccaaacagcat gtgaaaacaataacagaaaaatttgaagagctggatgagaggtggaaagctttaccaaaa actgttgataaaaggatcaactttcttcagtctcttgttgctgagcatgagcagtttgat gagctcctgctcaggttttcagactggattaagcagtttcttgctgaactacaagccact tcagagataaacacagctgatcaacaactagctgcatctcacaataagaatcactcaagg gaagtcgaaagtaagaaacagcagttacaaagtctgaaggaacatgtagataaattgtgt tctttcagctgcccagaggaccagcagacattgcagggaaagactgaagattgctttcaa atattccaggaggcaagtcaaataactagccaaagacaagaggctctggatcacctacgg gtattcctagagcaccatagtgttgcatcaggagtgctccaccagctgagacaggcagtg gagaaaacaggaaatatggataaagctaaatctgaattactggagaaggaactcagtaat gttattcaagatcttaacaagctggaatctgttgcaatcagtttggatggttcccttact aaggcccagtatcatttaaaacacagcatttctgagcagaggacctcctgcagggctctg gtggataatctgtgcttggaactggaggcagttcaaaacctgctgggaaccaaacagagt gaagcagaagctctgggagccttgcaaagatctttcatggaacgtaaagaacagttactg aaaagtattgaagatattgaagaaaaggctgacaaggaggccctgaaggaggcaacacta caagcccttcagcaaagattgaggatctttacccagttagatgaagaactgaattctcac cagcatgaactccagtggctcagggacagaggaaaacaaatagcccaaaaagatttcaca cttgctcctgagattgacaaagagataaattgcttagaatctctgtgggaggataccaag aaagttatacatgaaaaaaaggagcaatcctgcattcttattgatctgatgaaggaatat cagaccttgaagtcaacagtaatgaaagtcatagacggtgctgacagtgcttctgtgatc aaatccatttggaaggatcgtgaagatgtcaggcgaattttatcaaggcatgaagctgcc aagaatgatctgagtgataaacaaaaagacctggatactttcaccaataaaggaaaacat ttgttaacagaattaaaaagagtgcataactgtgactccactgcggtaaaaacagatatg aactctactgtggacaaatggctagatgtgtctgaaagaattgaaaacaacattgaccag ctaagtgtgaatgtggctctgtgggatgacatcctgaaaactggagatgaaatggatgga tggtgcaataaatgcatttctcaactgaatgaaggcatcagcaacttgagtaacagtcag agaatggaggtcctcctgaaagacttccagtctgaagtcaaggataaagaactgaagttg gatcagcttagttccaaaatttcagatctcaaagaactgacccatagtcaagatcctcct gcagatctccagtttatagaatcagatttgaggcagaagttggaacatgccaaagaaatg tcagagacagcaaaggagacactgaaagatttctgtactcagaaaatgcagttacagaag tttattgatcagatgacagactggttaacaaaagtggaagaaacactgttaagctgtgca cgtaacctgaatcctgaagctctaaataaagtgaaggaaacacaaaaagaccttcagctt cagcagagcagcattgactcgacccgtgagaacctcaacagcctgtgtcgcaaataccat tctgtagaactggaaactcttggtggcactgtcacttcattaataaaaaattatgaagct gtgaatctgctctgttccagaacacaggccagcatgcaagagtccttggaaaaacatttc cttcattctatgcaagaattccaggaatggttttctggtgtgaaggctgcagtaaaagaa tcatctgacaggtctggagacagcagcgtcatagaggcaaagctacacgacttgcagact gtgatggattctgttagcgagggacagaacaagttagatgctgcctgcaaggaaggtgaa agtttgtatgcttgcttaccaaaaccagttgtgagccatattcaggaccaaatagtgagg tctaaccagaacttccaggaattcctcaaccagtgtctgaatgataagaaggctctggaa gcttgtgcctcacacctgggaaactttgaagatcagcagaagaaacttggcctgtggata cgtgacatggaagaaagaataaccacagaagcattaggagagagcaaacagcttattcct gagaagaaaaaagaggtgcagaaagtggaaaagttcctggaagagttactaagttcaagg gaatcttttgataaactgtcccagatggcacagactttaaatgaggaaggccatggtgca gggagggaagtacgcctggcttctcaacatctcaccaattatcaaaacatggtcaaaact atcaaggagaagctgcgaacatgtcagcttgcactccaagagcatctcactttggaagag gcattacagagtatgtggtcatgggtgaaagaggttcaagataaactggcatcatcagag agcactgttggtagcaaagccacactagagagacgactgacacaaattcaggagatcctc ttactcaaaggagatggtgaagttaagctgaacatggccattggcaaaggagaacaagca cttagaagcaccaatgaggaaggacaaaaggtgatacaaactgagcttcagacgctgaag gatgtatggaatgacatcatcagcacctccatgaactggcagagctgcctagagtctgtc attggccagtggaatgaatatctggaaaggaaaaatcagctggaacagtggttagagaaa ttggatcacaaagtggaacagcctgtagaaccacagattggtctgaaggagaagtttgct cagctggaccacttccaggctgttgtttcagagatagaggatcactctggtgatttacag caactcattgaaaaagctgtggaactgtatgaaaaaacagaggatgattcttttggagaa gctgctcaagaagaactaaaaacacagtttaatgacatcacaactgtagccaaggagaaa atgaggaaagtggaagatattgtgaaggatcatttgctataccttgatgctgtgcatgaa ttcacagactggctccattctgcaaaggaagagctgcaccgctggtcagattcatctgga gatacatcgaccatacagaaaaagctggacaaaatcaatggggagctgctggccgcctgg tcgcagggcctggccccccgcgacagccggcacaccgacagcgaggtcctggagagctgg cgcaaggagaaagaaacattggatgctctgctaaagtctgaacatatgacagaagagatc aaaactcagttaaatgatctctgtagattttccagagatttgagtactcattcttcaaaa gtttcagggttgattaaggagtataacagtctctgcctgcaagcttcaaaaggatgtcag agcaaagagcagatcttgcagcaaagatttcggacggctttcagggacttccagcagtgg ctggtcaatgcaaaagtcaccacagccaaatgctttgatgtgcctcagaatatcagtgaa gctacagcaagtctgcagaaaatacaggaattcttatcagaaagtgagactgggcaacaa aaattaaacctgttagcatccaaaggagaattgctgtgctctgttttaccaaatgaaaag gcaaaagttatccaggacaaatctgctactgccaaagaagattggaaaaattttatcacc accctccaccagaaggaatctgcattggagaacttaaagatccagatgaaggactttgaa gcaactgctgagcctctacaggagtggttgaccacaactgagaagatggtacaaggaagt agcagtcggctccatgatcttccttccaagaggagagaacagcaaaagttgcagtctgtc cttgaggaaataagctgccacgagcatcagctcaacaggctgaaagagaaagctcagcag ctgggggaagagcaagctgacagcaaaagctttatgcgcagagtgtctcagttgtcttct caatatcttactctaagcaatctgacaaaggagaaagtttccagaatggatagggttgta gcagagcaccagcagttctcacacagtgtcaaggacctccaggactgggtggctgatgca gttcacatgctggattcctactgtcatcccactgcagacaagagtgttctggacagccgg atgttaaaactagagggactgctagcagtgaaacaagaaaaagaaatccaaatgaaaatg gttctgtccagaggagagtctgttttgcaaaatacatctctggagggagtaccagtgatt gaaaggcagttgcaaaccctgaaggacagctgggcttctcttctgtctgcttgtatccag tgcaagagtcaactggaaggagctctctccaaatggacaagttaccaggatgatgttcgt cagttttccagctggatggataaagtagaagccagtatgaatgcttctgaaaggcaatat gctgaactgagggaaaaaacagctgccctcagcaaagcaaagctactcagtgaagaggtg ttgagtcacagcagcctattggagacaattgaagtgaaaggaagtgggatggctgagcat tatgtcactcagcttgaactccaggaccttcaggagcggtataggttcctcaaagacaga acaaaggaggcagtaacaaaagctgaagaactgcttaacttacatcaagagtaccaaaga aatctgaaggcctttgaagtatggctggagaaggaacaggaaaaacttgactgtttatca catcttgatggtgatgcccagaaacaggaggcaatgctccgagacttacaggagctacag gtccactgtgtggaaggacaagcattattgaatgctgctgtccatgccagagaggaggtg attccctggggcattccacagatagaagacagagccctggaatccttacggcaggattgg caagtttatcagcacaggctttctgaggcaagaagccaattaaacgccactgtgagcaga ctgagattaatggagaaaaaatttcagaaggttaatgactggctaacagacctggaggag aaagttgctatcagaactgggaggcagtctggtagagcaacaaaggagatgcaacttcaa caaatgaagaagtggcatgaagaaatcacaatctacaaagatgatgtggaggaagttggg gtattggctcagcaaatactagaggaatgtctcactgcaagtagaatgggaagccaggct acacaactaacttctcgctaccaaactcttcttcttcatgtcttggagcaaataaagttt ctggaagaagaaatacgctgtatggatgagtcagaactggcttttagtgcctacacaaat tggtatggagctactaacaagaacttcagaaacgtgatcaccaagtttgatgtggttgat aaaacagcaatggagaaaaaagtgcagaaactagagctgttattgagcgatatggacata ggccacagtttactgaaatctgcccgtgagaagggggagcgtgctataaagtacatggaa gaaaatgaagttgaccagttaagaaaagaaattggagatcacgtggaacagcttgaagag ctggctggttccatcaggaaagagcacatgacttcagagaaatgccttcagctggcaaag gagttctcagacaaatacaaggcacagactcagtgggtcatggagtaccaagccatgtta catgctccagcggaaccaaagagtgagctctatgagaagaaggcccagttgtccaaatac aagtctatacagcagactgttctgtcccatgagccttcaataaaatcagtaattgaaaag ggagaagcactttttgatctggtgaatgatatgaatctaaagaacaacattcaagacctt cagagcacttaccaggaactctgcagcaccacaaaggcatacgttgaaaccttagaagtg agagtaaaagagcatgaggattacaatagtgatttgcaagaaggggagaaatggttacta catatgtctagcaggctggtaagccctgacctcatggagagtaacagtcttgaaataatc actcagcaactagctaaccacaaggctattatggaagaaattgcaggatttgaagatcgt ttgaacagccttaagagtaaaggcgattacttgatcaatcaatgcacagaacatcttcaa gcaaaatttaagcaaaacatacaaagccatctccaggggacaaaggacagctattctgcc atatgtagcacagcccaaagagtgtaccagagtttggaacacgaactccagaagcatgtt aatcatcaagataccctacaacaatgtcagacttggctgtctacagtgcagtcagagcta aagccaactacctggccacctttcagcctggcagatgcagttaaacaggtaaaacacttc cgggctctgcaggagcaggccaatacatacttggatcttctgtgctccatgtgtgatctg tcagatgccacagtgaagagtacagcaacagatgttcaacaaacaaaacaaacgattgag cagcagataatgcactcacagtatttggctcaaggttgggaagagatcaaacaaatgaag gctgagctctggatatatttccaggatgcagatcaacagctacagaatttgaaaaggaga cgggcagagttggagctaaacattgcccagaatatggtactccaggttaaggaattcagt cagaagttgcagtctaagcagtcagctcttacatctgtgactgagaagatgaacaaacta acccaaggacaggaatcacctgaacacaaggaaataggagaactcagcaaccaatggctg gatctctgccttcaggcacacagtttgctcatacagagggaggaggatctgcagaggaca ggggattaccatgatcgcatgaatgtagttgaagttttcttggaaaagctcacaaaagag tgggacaacctggctagatctgatgctgaaagtacaaatgtgcaccttgaagctttgcaa aaattggcactggcactagaggaaagaagatttgctctggaagatatgaaagatcagaaa cagaagatgatagaacatctgaatcttgatgacaaagaattaataaaggagcaatatggt cacttcgagcaacgctggactcagttggaggaccttgtcaaaaggaaaattcaagtttct gtttcaaccttagaagagctcagtttggtgcattccaaatttcaggaactaatggaatgg gcagaggagcagcaacctagtatctcagaggctcttaaacagagccctcctccagatttg gctcagagtcttctcatggatcatcttaccatttgcagtgagcttgaagccaaacagctt gttctgaaggtgcttgtgaaggatgctgacagggtgatgaccaacctagggctcaatgaa aggcaggagctgcaaaaagcactttctgatgcacagcaccatgtagaatgtctcagcgat ctggttggccagaggagaaagcacctcaataaagcactgtctgaaaagacccagtttctc atggcagtctttcaggctacaaaccaaattcaccagcatgagaagaaggtaacgcttcca gaacacatttgtctgttgccagaagatgtgaccaaacagatcaggacttgtaagaatgcc caggctaacctgaaagcctatcaaaatgaaatcacagggttgtgggctcaaggaagggat ttaatgaaagaagcaacagaacaagaaaagagtgaagtgttaggtaaactgcaagaacta cagaatgtgtatgactccgttttacaaaagtgtaatcagagattgttagagctggagaaa aatatggtttctaggaaatatttcaaagaagacttagataaagcttgccattggctaaaa caagctgatattgtcacattcccagaagtcaatgtaatgaattctaactctgaactatac aaccagttggcaaaatatcaacagattcttgagcaatctccagaatatgaaaatctgtta cttgcactgcaaagagatggccaagaaatcctaccatcacttaatgaagtagatcattct tatctggatgaaaagcttaacattctccctcagcaattcagtattgtcactgctctggca aaagaaaaattatataagattcaggaagcaatttatgccagaaaagagtatgcctctttg attgaattgacaattaaagctctgaatgagctagaagatcagtctattaacatggacaaa gctccagctactgtttcagccaaagaagctgtgtcactccagcaggcctacagagatctc ttaggtgaagtggtgagccttggtgcagcagtggatgaactaaaccagaagaaggaggcc tttcgaagcactggccagccatgggagccagatgagatgttaaaacttgtcacgctgtat cacaagttgaagaggcaaatagaacagaaaataaatctgttggaagacatgatagaagca tgccaggagcatgagaatatgtgtatgcagtttgaggcacaactagaggcagtgaagaag gagcagattaaggtaaatgaagaaacgctcccaatagaagaaaagttgaaaatctatcat tctttggtgggcagcttgcaagactcaggaagtcttctcaagcgaataaccgaacatcta gaagccctttctcctcagcttgactcatctgcatgtgagacaacagatcaccaagttcag tcttggcaagaaaaactgaagtctttgcatgctgccattagtgacactgtgatggactgt gagaacagacttgtgcaaagcatagacttccaaacagaaatctgccgctcccttgactgg ttgagatgggtgaaaacagaacttaatggaacattaagtttggacctcaaacttcaaagc atccaagaagaaatccgaaaggttcagatacatcaggaagaagtgcagtcaagcctgaga ataatgaatgcactgagcaataaagagaaagagagatacatgaaagcaaaggaactgata cctgctgacttggaaaacactcttgctgagctgacagaactagacggtgaagttcaagaa gctatacacacgagacaggctaccttgaataaattatatagcctctgccaaagatactac caagtgatgcagatagcaaatgactggcatgaagatgctcaggaatttctacgtttagca agaaatggtcttgatgttgagaactctgaggaaaacctaaggaaccacattgaatttttc agtacagaaagtcagttcggtaatcatttaaaggagttacagggccttgtgtcagagatg gagccctttatccaagacacagccagagagcagctattgcagaatgtagctgcattggag gaaaaggccaaagagacaaagcaagaagccaaagcccagcaagagcagttgcaaaggtgt gcttctgagtggcaggagtaccagacagcaagacagaaggttattgaagtgatgaatgag gctgagaaaaagttatctgatttctcagtagctaaagctgcttcttctcatgcagcagaa gagaaattgcaaacacataagactcttgtgtctgtagtgaattctttccatgagaagatc acagctctggaagaaaaggctttacagctggagaaagtcagtaatgatgccagtaaggca actataagtagatccatgacaacagtttggcagcgctggacacggcttcgcaatgtagcc caagaacaagagaaaattttggaagatgcagggcaggaatggaaagactttaatgataag attcagaaagccaccatagcaatagatcaactacaaggtcgcttaccagaaagctctgta gaaaaagcatccaaggcagagctcctggaactcctggattaccacagcactttccttctg gaggtggagcatcagctgtcgtctttgggcctgctcaaacagcatgttgtcagcatgctt caggatgtggaaataaagcctctgtctcaggaggaactaccagtcatgcaagaaatcaaa gcaatgcaagatcgatgtcacaatatgcaacagaaagtgaaaaaaggtgtgaagatggtg aaacaggagctgaaggagcgtgaggaggttgaaggagagattaatattgtgaagtcctgg atccaggaaacaaaagaatatttattaagccctgatatagaagtggatactcaacttcag gagttgcagtctctccttggtgaagtaactactcatcgccaggctgttgaaaaaatggct gaacaacaacagaataagtacttggggctttataccattttgccttctgaactctctctt catctagcagaagttgggctggcccttgtaactatacaggatcagattcaaaccaaagaa agagaaactcagcagatcaaaacactgaatcaagagtttggtcagaaaatccaggggata gcaaatgaactaaatgccattctttccaaactgaaaaagaaaacaaatgatatagcacaa gctaaacttgaacaaaagatccttggtgaagagttggacagctgcaatataaagctgttg gaattagatgcatcagtccaggactttgcagagcagaatgtgccgctggctaagcagctg gctaacaggatagggaaactcactgtactgcaccaacagaccgtacggcaagctgagtac agagcagccaagctcagtcaggctgcttcacatttggaagaatacaatgagatgctggag ttcatactgaaatggactgagaaagcaaatatcctagtgcatggtagtataatatggaat tcttcctctcagcttcgtgatcagtttaaagcctaccagactatgcttgatgagtctgga gagattcatggtgatcttgaggccatgagtgagaggattgagtatctggcaagtgtttac tgtactgaaggaatgtcacagcaagtgctggaactgggacgacggacagaggaattacag caagttatcaaagtgcgactaccaaatctccaagatgctgccaaggacatgaagaaattt gaagttgagttgagagtcctgcaggctgctctggagcaagcccaagctacactgacctct ccagagctcgggcacttgagcttgaaagagcagctttctcacagacagcatctgttgtct gaaatggagtcactgaagccaaaagttcaggcagtacaaatctgtcagagtgccctgagg attcctgaagaggtagtcaccggcctgcccatgtgccacagtgccctccggctccaggag gaggccagccgcctgcagcacactgccattcagcagtgcaacatcatgcaggaagcagtg gttcagtacgagcaatatgagcaagaaatgaaacatttacaccaaatgatagagagtgcc catcgtgagattcaagacaagccaatagcaaccagcaacatccaggaacttcaggtccag atttcacataatgaggagctggctcagaagatcaaaggataccaggagcaaattgcttct ttaaattccaagtgcaagatgctgacaatgaaagcaaaacatgctaccatgctgctgaca gtgacagaagtggaggggctttcagaaggaatggaagagctggattcagacctgctccca gcacaccccactcatccttctgtggttatgatgactgctggtcgctgtcacacgctgctc tcccctgtcactgaggagtctggggaggagggaaccaacagtgagatttcttctccacct gcctgtcgctctccctcacctgtggctaatacagatgcttctgttaaccaggacattgct tattaccaagccttatctgctgaacagttgcagacagaagctgctaaaattcaacccagc acttcagccacccaggaattttatgaaccaggcttagaatcagctgctagtgccaaattg gatgatttgcagcgttcttgggaaacactgaaaaatgtgatcagtgaaaaacagcgcacc ctctatgaagctcttgagcgtcaacagaaatatcaggacacgctccagtctatatccaca aaaatggagacaactgagatcaaactaaatgagagtcttgaaccagccaaaagtccagag agccaaatggctgaacatcaggctttgatggatgagattttaatgttacaagaggaaatc actgagcttcagacatcattagcccaagagctggtttcagaaccactggatgcagaagct ggtgatcaactggcattgcagtccactctcacagtcttggcagaacggatggccacaatt cgaatgaaggcatcaggaaaacgacaactattagaggagaaactgaatgagcaactggaa gaacagcggcaagagcaggctcttcaaaggtaccgttgtgaagctgatgagcttgaccac tggctactcaatacccgagcaacactgaactccgctttggttactgctgaggaacctatg gacatggaagcacagctggtggactgtcagaacatgctagttgaaatagagcagaaggtg atagccttgtcagagttgtctgtgcacaatgagaacttgcttatggaggggaaggctcac accaaggacgaggcagagcagctggctatgaagctcaggacactgaagagcagccttctg gagctgcagagagtgcttcacgacaaacagaccaacattcggggatcattacaagaaaag gaggagagtgatctggactttgtttcctcacaaagccccagtgtccaagaatggctggca caagcaagaaccactcgctcacagcaacagcagaacaccctgcagcaacagaaagagctg gaacaagagctagaagagcagaagaatctgcttcggtcagtagcatgtcgtggagaagaa atcctaacgcagcagggtgctccagaaggcctatgtataagtgacaagcctgatatactc tctgaggaattaggcttggaaggtgagaagccatcatctgaagaacagatgaaggtgaaa tgggaaagcctgaaccgggaattcaataccaagcagagactgctccaaaaggctttggaa caggaacagctgcagctttatagcagaccaaacagactgatatctggaatgcctctgtat aaggaggaaggacaggatgaagataaatcctcagtgtcaccagtattggatgaattgaat caggcctttgaagatgtgtcatctgaggctggacgggtggaggagagcctgcatcttgaa gagaagctgtatgatggtgtaatagcaacctccctgtggctagatggtgtggaagaacag gtctttgttgctacatctctgttgccagaggaacaaagagaaacatacctctgcaagcaa gagtctcttgccaaagaaatcaaagacataatggaagaaatggataagaacaagaattta tttgctaagatatttcctgagaatggtggcaatagggatatcatagaagacactttggat tgtctcctgagaagactgaccttactggagtcagtagtaaaccagagatgccatcagatg aaaggacagctccaacaaatagtgactttcaagaatgatctgaaactcctgtttacatcg gtggctgataacaaatatttagttctacagaaactagcagaggcagttgagagaccagaa acagaacaaatgcaggtcatactgcaggcagaagaaagtttgaaggaactagatgctgga atcaatgaattaaagaagcgtgtagacaaactagaaattgaccagtcttctgtgcaagag ctgtctaagatccaggataagtatgatgagctgatgatgatcattggatccagacggagt gacctgaatcagaatctggctcttaagaggcagtatgaacgggctttgcaggacctgact gacctggtagaaacaggccaagaaaagatggctggtgaccagaaaataattgttgcttct aaggaagaggttcaattgctacttgacaaacataaggaatattttcaggggttagagtct cacatgatcctgacagaaacactctttagaaagatgagtagctttgccctcttgaagaaa actcagtcacattcagagctaatgacacaagcttcagctgtattaaagctggctcataaa cgaggcgtagagctggaatacattctagagacctggatgcatctggatgaagattaccag gaacttaccagacagctggagtctgttgaagataacatccccactgttggtttggtggaa gagacagaggagaggcttacagatcggattacactttttcagcatctgagatctaacctg aatgaataccaacctaaattataccaagtgctagatgatgggaaaaggctccttttttct attagctgctcagatcttgaaagtcaactgaaccaactaggagaacagtggttaagtaac accagcaaggttaccaaggagctccacaggcttgagacaatactgaagcactggacaagg tatcagagtgaatcaaatgaattggcacattggttacaatctgcaaaggagcgacttgag ttttggagccagcagtctttgacagttcctcaggaactggaaacagtccgagaccatctg aactcctttttggagttttcaaaagaagtggatgctaaatcatcacagaaatcttctgtc ctgagtactgggaaccagctcctcaggctgaagaaggtggatacagcagcattgcgtgcg ggattgtcccacattgacagtcagtggacagatctcctcacacaaatcccagcagttcaa gagaaactgcaccagctccagatggacaaaattccttctcgccatgctatcactgaagtt atgagctggatttccctcatggaaaatgtcattcagcaggatgaagagaatataaaaaat gtagtaggacagaaagtcattcaggattatgtccagaagtacaagggtttcaagatagat ttaaattgcaaacaattgacggtagactttgtgaaccaatcagtgctacagattagcagc caggatgttgaaagtaaacgtagcgacaaaactgattttgcagaacagctcggagcaatg aacagacgttggcagatcctgcaaggcctgataacagaaaagattcagctgttggaaagt ctgcaggaatcctggacagaatatgaaaataatgtgcagtgcctaaaaacttggtttgaa acccaagagaagaagctgaaacagcaacagaaaattggagaccaggcttcagtacagaat gctttgaaagactgtcaggaattagaagaattaataagaacaaaggaaaaagaagtagaa aatgtagaacagagtggtctttctttggtacaaaacaagaacgaagaagtctcttctgct gttatgaatacactgcaagaaattaaccattcctgggccaatttggatcacatggttagc caactgaagatattgttgcaatctgttcttgatcagtggagcatttacaaagaggcttat gaagaactgaatggttacctaacagaagccagatattctttgtcccgtttttatcttctt actggttctttggaagcagtgaaaatccaagttgataaccttcagagcctacaagatgaa ttggaaaagcaagaaaatagcttacagaaatttggttctgtgaccaatcagttgttgaaa gaatgtcaccccccagtgactgaaactcttaccaacactttgaaagaagtgaatatgagg tggaacaaccttctgcaggagattgcagagcggctgcgtgccagtaagggcctccttcag ctgtggcagaggtacaaggactgttaccagcagtgctcttccatagtccgtcagcgggaa gaccagactaatgaactcttgaagactgccaccagcaaagacattgctgatgatgaagtt actacttggattcaggactgtaatgatgtactcacggatttgaagacagcacaggataca ctgattgtgcttcaagaattgggagaggagctaaaaagccaggtggagccttcagcagca gcagctatacagtctgatcatctttctctgagccagaatctgtcaaccctagaacaggct ctccacaagcaacaggttgtacttcaggctggagtgctggactaccaaacctttgccaag aacctgcaagtccttgaggcctggataacagaagcagaagaaatattgaaaggacaggat cccagtcactcatctgatctctcaacaatacagagtagaatggaggaacttaagagtcaa atgttgaagttcagcagcatggccccggatttggaccgtcttaatgagctgggttacagg cttcctctgaatgataaagaaatcaaaaggatgcagaacctgaacagacattggtctctg atctcatctcagactacagagagattcagtaagctgcagtctttcatgctgcagcaccag accttcttggagaaatgtgagacttggatggatttattagttcagactgagcagaagctg gcagcagagatttcaggaaactaccagagccttctagagcaacagagggcacatgagcta ttccaggcagagatgttcagccgccagcagattttacattcaattatctctgatgggcag cacctcctagaacaaggacaggtggatgacagggatgaatttaatctgaagctgactctt ctaagcaatcaatggcaaggagtaattcgccgggcacagcagaggagggggatcattgac agtcagatacatcagtggcaacgctatagggaaatggcagagaagctgcgcaagtggctg gtggaaatatcctgtcagctagtgagtgggctgggcaatgttcccatcccattgcagcaa gccagagcactgctggatgaagtgcagcttaaagagaaagttctcctaagacagcaaggg agttatatcctcactgtggaagctgggaagcaactattgctctctgctgacagtgaagct gaggcagccctgcagacagaacttaccgaaattcaggagcgctggaagatagctagcacc caactggagcaacaaaagaaacagcttgctttactactgaaagactgggaagaatctgaa aagggcatcggagactccctggagaagctaagatcattcaaaaaaaagctttctcaacct ttgccagaacaccatgatgaattgcatgcagagcagattcgttgcaaggagttagagaat gctgttgaaggatggacagatgaccttgcacacctctctctactgaaggaaaccctgtct atatatatcagcgcagaagatatctcaatccttagtgagcgcatagagcttctacacaga cagtgggaggagctgtgccaccaggtctccttacgtcgacaacaagttagtgaaagactg aatgagtgggctgtcttcagtgagaagaacaaggagctctgtgagtggttgacacaaatg gaaagtaaggtttctcaaaatggtgacatcctcatagaagaaatgattgagaaacttaaa aaggattatcaagaagaaattgctgtagcccagaagaacaaaatccagctccagcaaatg ggagagcgacttgctaaagccagccatgagagcaaggcatcagagattgagtataaactt ggcaagatcaatgacaggtggcaacatcttctagatcttattgcagccagggtaaagaag ttgaaggagaccctcgttgcagtgcagcagctggataagaacatgagtagcctgagatct tggcttgcccacattgagtcagagctgtccaaacctatcgtctatgaaacttgtgactct gaggagatacaaaggaagttaaatgaccagcaggaactacagagggacatagagaaacac agcactggagtggcatctgttctcaatctgtgtgaagtacttcttcatgactgtgatgct tgtgccacagaagcagagtgtgactctatccagcaggctacacgcaatttggacagaagg tggaggaacatttgtgcaatgtcaatggaaagacgacttaaaattgaagagacgtggcgg ctgtggcaaaagtttttggatgactactctagattcgaagagtggctaaaagtctctgag aggacagctgctttcccaagctcctctggtgtactttacacaattgctaaggaagaactg aagaaatttgaggccttccagagacaagtgcatgaaagtctgactcagctggaactgatc aataaacagtatcgccgcctggcccgagagaaccgcactgactctgactgcagcctcaaa cagatggttcatgaggggaatcagagatgggacaacttacagaagcgagttacctccatc ctgcgcagactaaaacattttattggccagcgtgaggagtttgagacagcacgtgatagc atcttggtatggctaacagaaatggacctgcagctgaccaacattgagcatttctcagag tgtgatgtccaagcaaagataaagcaacttaaggcgttccagcaagaaatttcactaaac aacaacaaaattgagcagataattgtgcagggtgagcaactcattgagaagagtgagccc atagacgcagctgtcattgaagaagaactagatgagctgcgtcgttactgtcaagaggtc tttggacgtgtggaacgttatcacaagaaactcatccgtcttcctctgacagatgacgaa catgacctctctgacagagaggtggatctggatgaatcagcagatctctctgacatacac tggcatgacaaatctgcggacagcattctctccccgcacccctcttccaacctttcgctg cctctttcccagccggtgagaagcgagcgatcagggcgagatactcctgcgagtgtggac tccattcccctggagtgggatcatgactacgaccttagcagggacctggagacagctgtt tcacaggcactgcactctgaggaagaagatggaggacaagagaaggacttctacctgaga ggagcagctggtatagcagatgtagagatccctgaaactcttgaggcctatgtaacactc acagaaaacacactcaaaaatctctctggagaacctggtgccctggaagcacatatccga cagctggacaaggcattagacaccagtcgttttcaaatacagcaaacagaaaacatcatc cgcagcaaaacacctacaggaccagagctggattccagttacaaaggatatatgaagcta ctaggtgagtgcagtggaagcatagactcagtaaaaaggcttggatataaactgaaggag gaagaagaaaaattatctggacttattaacctcaacagcactgaaacacaaacagctggt gtaattgaccgatgggaattaatccaggctcaggctctaagcaaggagctgaggatgaag cagaaccttcagcaatggcagcagtttaactctgaccttaatagcgtttgggcttggctt ggagaaactgaagaggaactggagaagctccaccaccttgatctcagcactgacatacaa actattgagctcagaatcaaaaaattgaaagagctgcagaaagcaattgataaccgcaaa gcaatcatcttatccatcaatctgtgcagctcagagttcactcagtctgacagtgaggag agcaagaagcttcaagagcgtctgtctcagatgaatgtgcgctgggaccacgtatgcagt atgattgaagagtggcgctgctcattgcaggatgcattaatgcaatgccaggatttccat gaaatgagccatggtttgctgctttggttagagaatattgacagaagaaaaaatgaaatt gtgcccatcaatccaaacctggacccagaaatgctgcaggatcatcacaggcttctaatg caaatcagacgtgaactgctggagtctcagttgaaggtggcatcgctacaagatatgtcc tgccaattgctagtcaatgctgaaggcaaggactgtcttgaagccaaagaaaaggtgcat gtcattggaaacagactgaagcttctcttgaaagatgtcatacgtcatattaaagaccta gagaaaattctagacatttcaagtagtcagctggaattgtcctcatggtcctctgctgat gaattagacacatcgggctcagtgagtcctgtatccggaagaagcactccaagcagacag agaacgccacggggcaaatgtagtctctcacagcctggaccctctgtcagcagtccacat agcaggttcacaagaggtggctcaggttcctccccttctgaggctgggccagcatggcgg cacccatccttcttcctcagagtcctcagagctgctctgccacttcagctcctcttgctg ctcctgatcgggctggcttgcctggtgccaatgactgaggaggactacagctgtactatg gccaataactttgcccgctctttccaccctatgctgaaatacatgaatggtccacctcca ttatga

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