KEGG   Athene cunicularia (burrowing owl): 113478160
Entry
113478160         CDS       T05777                                 
Symbol
PLCB4
Name
(RefSeq) 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 isoform X1
  KO
K05858  phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
Organism
acun  Athene cunicularia (burrowing owl)
Pathway
acun00562  Inositol phosphate metabolism
acun01100  Metabolic pathways
acun04020  Calcium signaling pathway
acun04070  Phosphatidylinositol signaling system
acun04081  Hormone signaling
acun04082  Neuroactive ligand signaling
acun04261  Adrenergic signaling in cardiomyocytes
acun04270  Vascular smooth muscle contraction
acun04310  Wnt signaling pathway
acun04371  Apelin signaling pathway
acun04540  Gap junction
acun04621  NOD-like receptor signaling pathway
acun04912  GnRH signaling pathway
acun04916  Melanogenesis
Module
acun_M00130  Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Brite
KEGG Orthology (KO) [BR:acun00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    113478160 (PLCB4)
 09130 Environmental Information Processing
  09132 Signal transduction
   04310 Wnt signaling pathway
    113478160 (PLCB4)
   04371 Apelin signaling pathway
    113478160 (PLCB4)
   04020 Calcium signaling pathway
    113478160 (PLCB4)
   04070 Phosphatidylinositol signaling system
    113478160 (PLCB4)
  09133 Signaling molecules and interaction
   04082 Neuroactive ligand signaling
    113478160 (PLCB4)
   04081 Hormone signaling
    113478160 (PLCB4)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04540 Gap junction
    113478160 (PLCB4)
 09150 Organismal Systems
  09151 Immune system
   04621 NOD-like receptor signaling pathway
    113478160 (PLCB4)
  09152 Endocrine system
   04912 GnRH signaling pathway
    113478160 (PLCB4)
   04916 Melanogenesis
    113478160 (PLCB4)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    113478160 (PLCB4)
   04270 Vascular smooth muscle contraction
    113478160 (PLCB4)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:acun04131]
    113478160 (PLCB4)
Enzymes [BR:acun01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.4  Phosphoric-diester hydrolases
    3.1.4.11  phosphoinositide phospholipase C
     113478160 (PLCB4)
Membrane trafficking [BR:acun04131]
 Exocytosis
  Calcium ion-dependent exocytosis
   Phospholipases
    113478160 (PLCB4)
 Endocytosis
  Macropinocytosis
   Phospholipase C
    113478160 (PLCB4)
SSDB
Motif
Pfam: PI-PLC-X PH_14 PI-PLC-Y PLCB1-4-like_EFh EF-hand_like PLC-beta_C C2 EF-hand_7 EF-hand_6
Other DBs
NCBI-GeneID: 113478160
NCBI-ProteinID: XP_026700881
LinkDB
Position
3
AA seq 1210 aa
MAKPYEFNWQKPVPSFMQDGAVFDRYEEESFVFESSCLFQVDEFGFFLSWKSEGKEGQVL
ECSLINSVRFGAVPKDPKILTALEAVGKSENELEGRIVCVCSGTDLVNISFTFMVAENTE
IAKQWVEGLGSIIHNFRANNVSPMTCLKKHWMKLAFLTNTNGKIPVRSITRTFASGKTEK
VIFQALKELGLPSGKNDEIEPAAFTYEKFYELTQKICPRTDIEDLFKKINGDKTDYLTVD
QLVSFLNEHQRDPRLNEILFPFYDTKRAMQIIETYEPDEDLKSKGVISSDGFCRYLMSDE
NAPVFLDRLELYQEMDHPLAHYFISSSHNTYLTGRQFGGKSSVEMYRQVLLAGCRCVELD
CWDGKGEDQEPIITHGKAMCTDILFKDVIQAIKETAFVTSEYPVILSFENHCSKYQQYKM
SKYCEDLFGDLLLKQPLETHPLDTGKALPSPNDLKRKILIKNKRLKPEVEKKQLDALKKM
MEAGETAAPVNILEDDNEEEIESADQEEEAHPEYKFGSDLTVDDYSQKEAVAISVKKAVE
DSEQENNKKGLVTVEDEQAWMASYKYVGATTNIHPYLSTMVNYAQPVKFQGFDVAEGNIK
ERNIHHNMSSFNESVGLGYLKTHAIEFVNYNKRQMSRIYPKGGRVDSSNYMPQIFWNAGC
QMVSLNYQTPDLAMQLNQGKFEYNGSCGYLLKPDFMRRPDRTFDPFSETPVDGVIAATCS
VQVISGQFLSDKKIGTYVEVDMYGLPTDTIRKEFRTRMVMNNGLNPVYNEESFVFRKVIL
PDLAVLRIAVYDDNNKLIGQRILPLDGLQAGYRHISLRNEGNKPLSLPTVFCNIVLKTYV
PDGFGDIVDALSDPKKFLSITEKRADQMRAMGIETSDIADVPNDTSKNDRKGKANNAKAN
VTPQSSSELRPSTTTGFGSGTDAKKGIDLIPQVKIEDLKQMKAYIKHLKKQQKELNALKK
KHAKEHSAMQKLHCTQIDKIVAQYDKEKVSYEKMLEKAIKKKGGSNCLELKKETEIKIQT
LTSDHKSKVKEIVAQHTKEWSEMINTHSAEEQEIRDLHLNQQCELLKKLLINAHEQQTQQ
LKFSHDRESKEMRANQAKISMENSKAISQDKSIKNKAERERRVRELNSSNTKKFLEERKR
LAVKQSKEMDQLKKVQLEHLEVLEKQNEQLLKSCHAVSQTQGKGDAADGEAGSRDGSQAS
NSGLKPQQAN
NT seq 3633 nt   +upstreamnt  +downstreamnt
atggcaaaaccttatgaatttaactggcagaagccagttccctcctttatgcaagatgga
gctgtgtttgatagatacgaagaggaatcttttgtctttgaaagcagctgtctcttccaa
gtggatgaatttggcttttttctgagctggaaaagtgaaggaaaggaaggacaggtatta
gaatgctccctgatcaacagtgttcgttttggagctgtaccaaaggatcccaaaatacta
actgcacttgaggctgttggaaaatcagaaaatgagttggaaggacggatagtgtgcgtt
tgcagtggcacagatctggtgaacatcagcttcactttcatggtagcggaaaacacagaa
atagccaagcaatgggtagaagggcttggatccatcatacataattttagagctaacaat
gtcagtccaatgacatgtctcaagaaacactggatgaagctggcctttctaacaaacaca
aatgggaaaattccagttcggagcattaccagaacctttgcatcaggtaaaacagaaaaa
gtgatctttcaggcacttaaggaattaggtcttcccagtggaaagaatgatgaaattgag
cctgcagcatttacttatgagaaattttatgagctcacccaaaagatatgtccccgaact
gacatagaggatctgtttaagaagatcaatggagacaaaactgattatttaacggtagac
caattagtgagctttctaaatgaacatcaacgagatcctcggctcaatgaaattttattt
cccttttatgacacaaaaagagcaatgcagataattgagacatatgagccagatgaagac
ttgaagagtaaaggtgttatatcgagtgatgggttttgcagatacttgatgtcagatgaa
aatgccccagttttcctagaccgtttggaattatatcaagaaatggatcatcctttggct
cattatttcatcagttcctctcacaatacatacttaacaggcagacagtttggtggcaag
tcttcagtggagatgtacagacaagtgcttttggctggatgcaggtgcgttgagctggac
tgttgggatggcaaaggtgaagatcaggaaccaataataacgcatggaaaagcaatgtgt
acagatattcttttcaaggatgtaattcaagccattaaggaaacggcatttgttacgtca
gagtatcctgtcattctttcatttgaaaatcactgcagcaaataccaacagtacaagatg
tcaaaatactgtgaagatctttttggagatctcctgttgaagcaacctctagaaacacat
ccacttgatacaggtaaagccttaccttctcctaatgacctcaaaaggaagattctcata
aagaataaaaggctgaaacctgaagtagaaaaaaaacagcttgacgctctgaaaaaaatg
atggaggctggggagactgctgctcctgtaaatatcctagaggatgataacgaagaagaa
atagaaagtgctgaccaggaagaagaagctcatccagagtacaaatttggaagtgacctt
actgtagatgattacagtcaaaaagaagctgttgccatcagtgtcaaaaaggctgttgaa
gattctgagcaagaaaacaataaaaagggtttagtaactgttgaagatgaacaagcgtgg
atggcatcttacaaatatgtaggtgccacaaccaatatacatccatatttatcaacaatg
gtcaactatgctcaacctgtaaaatttcaaggtttcgatgtagcagaaggtaacataaaa
gaacgtaatattcatcacaacatgtcctctttcaatgaatcagtcggactaggttatttg
aagacacatgccattgagtttgtgaattataataaacgacaaatgagtcggatataccca
aagggaggccgagtggattccagtaattacatgcctcaaattttctggaacgctggctgc
cagatggtctcactgaactatcagaccccagatttagcaatgcagttgaatcaaggaaaa
tttgaatataatggatcatgcgggtatctactcaaaccagatttcatgcgacgaccagat
cgaacatttgaccctttctctgaaactcctgtagatggtgtaattgctgcaacatgttct
gtacaggtaatatctggtcagttcttatcagataaaaaaattggtacgtatgtagaagtg
gatatgtatggtttacccacggacacgatacgtaaagaatttcgaacacgcatggtgatg
aacaatggtctgaaccctgtttataatgaagaatcatttgtatttcgaaaggttattctc
cctgatcttgctgtcctgagaatagcagtgtatgatgacaataataagttgattggtcag
aggatcctgcctctggatggtctgcaagcaggttacagacacatttctcttcggaatgag
ggcaacaaaccactctctcttccaacggttttctgcaacattgtgcttaaaacatatgtg
cctgacggttttggagatattgtggatgctttatcagatccaaagaaatttttgtctatt
acagaaaaaagagcagaccaaatgagagctatgggtattgaaactagtgatatagctgat
gtaccaaatgacacatcaaagaatgataggaaaggaaaagccaataatgccaaagcaaac
gtaacgcctcagagtagctctgaacttcgaccaagtaccactacaggctttggatctgga
accgacgctaagaaaggtatagaccttattccccaagtgaagatagaagatttgaagcaa
atgaaggcttatataaagcatttaaagaaacagcagaaagaactgaatgccttaaagaag
aaacatgcaaaggagcacagcgctatgcagaagttgcactgcacacaaattgacaaaata
gtggcacaatatgataaagaaaaggtatcatacgagaaaatgttagagaaggcaatcaag
aagaagggaggaagtaattgtcttgaactgaagaaagaaacggaaattaaaattcagacg
ttaacatcagatcacaaatctaaggtcaaagagattgtggcacagcacactaaagagtgg
tctgagatgatcaatacgcacagtgccgaagagcaagagatccgtgatttacatttgaac
caacagtgtgaactactgaagaaactgctgattaacgctcacgaacaacaaacccagcag
ctaaaattttcacatgacagggaaagcaaggaaatgcgtgccaatcaggctaaaatatct
atggagaacagcaaagccataagccaagacaagtctatcaaaaataaagctgaaagagag
aggcgagtcagagaactgaacagcagcaacactaaaaagttcctggaagagagaaaaagg
ctggcagtaaagcagtcaaaagaaatggatcagttgaaaaaagttcaacttgagcattta
gaagtcttggagaagcagaacgagcagcttttgaaatcctgtcatgcagtgtctcaaaca
caaggcaaaggagatgcagcagatggtgaagctggaagcagagatggatcgcaggccagc
aacagtggtctgaagcctcaacaagcaaattga

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