Azotobacter chroococcum: Achr_8290
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Entry
Achr_8290 CDS
T03640
Symbol
leuA
Name
(GenBank) 2-isopropylmalate synthase LeuA, allosteric (dimerization) domain
KO
K01649
2-isopropylmalate synthase [EC:
2.3.3.13
]
Organism
acx
Azotobacter chroococcum
Pathway
acx00290
Valine, leucine and isoleucine biosynthesis
acx00620
Pyruvate metabolism
acx01100
Metabolic pathways
acx01110
Biosynthesis of secondary metabolites
acx01210
2-Oxocarboxylic acid metabolism
acx01230
Biosynthesis of amino acids
Module
acx_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
acx00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
Achr_8290 (leuA)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
Achr_8290 (leuA)
Enzymes [BR:
acx01000
]
2. Transferases
2.3 Acyltransferases
2.3.3 Acyl groups converted into alkyl groups on transfer
2.3.3.13 2-isopropylmalate synthase
Achr_8290 (leuA)
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Motif
Pfam:
HMGL-like
LeuA_dimer
HCS_D2
DUF3280
CHASE3
Motif
Other DBs
NCBI-ProteinID:
AJE20317
UniProt:
A0A0C4WQ05
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All DBs
Position
923686..925236
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AA seq
516 aa
AA seq
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MSSKDRVIIFDTTLRDGEQSPGASMTKDEKLRIAKVLERLRVDVIEAGFAIASPGDFEAV
KAIAESIKDSTVCSLARAVDADIERAAEALKNANSGRIHTFIATSPIHMQYKLRMQPDQV
VEQAVRAVKKARSLCADVEFSCEDAGRSEIDFLCRIIEAAIAAGARTINIPDTVGYAIPH
QYGEMIGQLLARIPNADQAVFSVHCHNDLGLAVANSLAAVVAGARQVECTINGLGERAGN
AALEEIVMAIKTRHDLLGVYTNIDTPHILAASRLVSGITGFPVQPNKAIVGANAFAHESG
IHQDGVLKHRETYEIMSAQSVGWHTNKMVLGKHSGRNAFRTRLEELGIQLADDAALNAAF
ARFKALADKKHEIFDEDLQALVSETQDEEAPEHYRLHALEVVSKSGTVPRAHLRLTVAGS
DQEATAEGAGPVDAIFKAIESVAASQASLQLYSVNAITEGTDSQGEVTVRLEKGGRIVNG
NGADIDILVASAKAYINALNLMRAGVPKAHPQAADV
NT seq
1551 nt
NT seq
+upstream
nt +downstream
nt
atgagcagcaaagaccgcgtcatcatcttcgacaccaccctgcgcgacggcgaacagagc
cccggcgcctccatgaccaaggacgagaagctgcgcatcgccaaggtactggagcggctc
agggtagacgtgatcgaggccggcttcgcgattgccagcccgggcgacttcgaggcagtc
aaggcgatcgccgagagcatcaaggacagcaccgtgtgcagcctggcgcgcgccgtggat
gccgacatcgagcgcgctgccgaggcgctgaagaacgccaattcggggcgtatccacacc
ttcatcgccaccagtccgatccacatgcaatacaagctgcgcatgcagcccgaccaggtg
gtcgagcaggccgtgcgggcggtgaagaaggcgcgcagcctgtgtgccgacgtggagttc
tcctgcgaggacgccggccgttcggaaatcgacttcctctgccggatcatcgaggcggcc
atcgctgccggcgcacgcaccatcaacattccggacaccgtcggctacgccatcccgcac
cagtacggcgagatgatcggccaactgctcgcgcgcatccccaacgccgaccaggcggtg
ttctcggtgcactgccacaacgacctcggcctggccgtggccaattcgctggccgcggtg
gtggccggggcgcgccaggtggaatgcaccatcaatggcctcggtgagcgtgccggcaat
gccgcgctggaggagatcgtcatggcgatcaagacccgccacgacctgcttggcgtctac
accaacatcgacactccgcacatcctcgccgcctcgcggctggtttcgggaatcaccggc
ttcccggtacagccgaacaaggccatcgtcggcgccaacgccttcgcccacgagtcgggc
atccaccaggacggcgtgctcaagcaccgcgagacctacgagatcatgtcggcgcagtcg
gtcggctggcacaccaacaagatggtgctgggcaagcactccgggcgtaacgccttccgt
acccgtctggaggagctgggcatccagctcgccgacgacgctgcgctgaatgcggccttc
gcccgcttcaaggcactggccgacaagaagcacgagatcttcgacgaggacctgcaggcg
ctggtctccgaaacccaggacgaggaggccccggaacactaccggctgcacgccctggag
gtcgtctcgaagagcggtacggtgccgcgggcgcacctgcggctcaccgtcgccggcagc
gaccaggaagcgacggccgagggtgccggcccggtggacgcgatcttcaaggccatcgag
tcggttgccgcttcccaggccagcctgcagctctattcggtcaacgccatcaccgagggc
accgactcccagggcgaggtcaccgtgcgtctggagaagggcgggcgcatcgtcaacggc
aacggcgccgacatcgacatcctggtggcctcggccaaggcctacatcaacgcgctgaac
ctgatgcgtgccggcgtgcccaaggcccatccgcaggcggccgacgtttga
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