Anser cygnoides (swan goose): 106031696 Help Entry 106031696         CDS       T04896                                  Symbol RYR3 Name (RefSeq) ryanodine receptor 3 isoform X10   KO K04963   ryanodine receptor 3 Organism acyg  Anser cygnoides (swan goose) Pathway acyg04020   Calcium signaling pathway acyg04371   Apelin signaling pathway Brite KEGG Orthology (KO) [BR:acyg00001]  09130 Environmental Information Processing   09132 Signal transduction    04371 Apelin signaling pathway     106031696 (RYR3)    04020 Calcium signaling pathway     106031696 (RYR3)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04040 Ion channels [BR:acyg04040]     106031696 (RYR3) Ion channels [BR:acyg04040]  Voltage-gated cation channels   Ryanodine receptor    106031696 (RYR3) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  RYDR_Jsol RYDR_ITPR RyR RR_TM4-6 MIR SPRY Ins145_P3_rec RIH_assoc Ion_trans EF-hand_7 EF-hand_1 EF-hand_6 EF-hand_8 TBK1_ULD Motif Other DBs NCBI-GeneID:  106031696 NCBI-ProteinID:  XP_013029688 LinkDB All DBs Position 5:27032448..27266613 Genome browser AA seq 4863 aa AA seqDB search MAEGGEGGEDEIQFLRTDDEVVLQCVASVHKEQRKFCLAAEGLGNRLCFLEPTSEAKYVP PDLCICNFVLEQSLSVRALQEMLANTGDNASEGAAQGGHRTLLYGHAILLRHSFSEMYLT CLTSSRSQTDKLAFDVGLRENAAGEACWWTIHPASKQRSEGEKVRIGDDLILVSVSSERY LHLSMSNGSIQVDASFMQTLWNVHPTCSGSNITEGYLLGGHVVRFFHGHDECLTIPSTDQ NDSQQKKVLYETGGAGVRARSLWRVEPLRISWSGSNIKWGQPFRLRHITTGMYLALNDDE GLVMLDREKSDTTSTAFCFRASKELKEKQDSTLKRDIDGMGVPEIKYGDSVCFVQHVASA LWLTYKAQDAKSARLGLLKRKVILHQEGHMDDGLTLQRCQHEESQAARIIRNTTSLFSQF LSGNNRTLSPIALPVEEMAQTLQDLITYFQPPEEDLEHEDKQSKLRSLKNRQNLFKEEGM LALVLNCIDRLNDSNSAAHFAEIAREENGTTWKEILNLLYKLLAALIRGNRNNCTQFSSN LDWLISKLDRLESSSGILEVLHCILIESPEALNIIAEEHIKSIISLLDKHGRNYKVLDVL CSLCVCNGVAVRANQNLICDNLLPRRDLLLQTRLINDVTSIRPNIFLGVAEGSAQYKKWY FELIIDQVDPFLTAEPTHLRVGWASTSGYAPYPGGGEGWGGNGVGDDLYSYGFDGLHLWS GRVPRAVASVNQHLLSSDDVVSCCLDLGVPSISFRINGQPVQGMFENFCTEGFFFPVVSL SAGVKARFLLGGRHGEFKFLPPAGYAPCYEALLPKEKMKLEPVKEYKRDSDGVRDLLGTT QFLSQASFIPCPIDTSQIALPFHLEKIRDKLAENIHELWGMNKIELGWTYGKIRDDNKRH HPCLVEFSKLPETEKNYNLQMSTETLKTLLALGCHIVHANPAAEEDLKKVKLPKNYMMSN GYKPAPLDLSEVKLLPSQEFLVDKLAENAHNVWAKDRIKQGWTYGIQQDLKNKRNPRLVP YALLDERTKKSNRDSLREAVRTFAGYGYSVEPPDQEIADQTTEKVSIDKIRFFRVEQSYA VKSGKWYFEFEAVTGGDMRVGWARPGCRPDIELGADDQAFVFEGSKGQRWHQGSGFFGRS WQPGDVVGCMINLDDKSIIFTLNGELLITSKGSELAFADFGIESGFVPICALGLSQIGRM NLGMDASTFKYYTMCGLQEGFEPFAVNMNRDVAMWFSKRLPTFVNVPKNHPHIEIWRIDG TIESPPRLKVTHKTFGTQNSSSDMIYCRLSMPVEFRSSFNFGMGVENASSDVFQKRKHSQ EVSVPSTTYFYSLRIFAGQDPSCVWVGWVTPDYHFYSENFDLNKNCTVTVTLGDERGRVH ESVKRSNCYMVWGGDITSNSQRSGRSNVDLEIGCFVDLATGMLSFTANGKELGTCYQVEP NTKLFPATFVQPTSTNLVQFELGKLKNTMPLSAAIFKSEERNPVPQCPPRLDVQTITPVL WSRMPNSFLKVETERVSERHGWVVQCLEPLQMMALHIPEENRCVDILELCEQEDLMKFHY HTLKLYSSVCALGNTRVAYALCSHVDVSQLFYTIDNQYLPGLLRSGFYDLLISIHLEHAK QAKLMMNNEFIIPVTEETRTIRLYPDETKKHGLPGVGLSTCLKPGFHFSAPCFIVTSEEH QTSSPEIPLDTLKSKAISMLTEAVQCSGAHIRDPVGGHIAFQFVPVLKLIATLLIMGVFD DDDVKQVLILIDPNVFGDHKEETEEGTEKEEVTQVEEKAVEAGEKAIKETKAPTTGLLQT RLPESVKLQMCHLLNYFCDCELQHRVEAIVSFADRYVSKLQYNQKYRYNELMQALNMSAA LTAKKTKEFRSPPQEQINMLLNFQLGEDCPCPEEIRDELYDFHDDLLIHCGIPLEEEEEE EEDSTLTGKLRSLIYKIKGPPKAEKVEPREEEEKSPTTLKELISQTMVRWSQEDQIQDPE LVRIMYTLLRRQYDSIGELLQALRKAYTISATSVKDTINLLAALGQIRSLLSVRMGKEEE LLMINGLGDIMNNKVFYQHPNLMRVLGMHETVMDVMVNVLGGDKSQIVFPKMVASCCRFL CYFCRISRQNQKAMFEHLSYLLENSSVGLAFPSMRGSTPLDVAAASVMDNNELALALEEP DLDKVVTYLAGCGLQSCPVLLAKGYPDIGWNPIEGERYLSFLRFAVFVNSESVEENASVV VKLLIRRPECFGPDLRGEGGNGLLAAMQEAIRISENPSRDLPSQGYRREGDEEEEEEEIV HMGNAIMSFYSALIDLLGRCAPEMHLIQSGKGEAIRIRSILRSLVPTEDLVGIISIPLKL STVNKDGTVNEPDMSANFCPDHKAPMVLFLDRVYGIKDQSFLLHLLEVGFLPDLRASASL DTVTLSTTEAALALNRYICSAVFPLLKRCAPLFSGTEHHASLVDSMLHTIYRLSKGRSLT KAQRDTIEECLLAICHHLRPSMLQQLLRRLVFDVPLLNEYCKMPLKLLTNHYEQCWKYYC LPSGMGSYGIAAEEELHLTEKLFWGIFDSLSHKKYDPELFRMALPCLSAIAGALPPDYLD TRIRSTLEKQTSVDPEGNFDPKPVSTANLVLPEKLEYIVSKYAEHSHDKWAFDKTNNGWK YGVSLDENTKTHPLIRPFKTLTEKEKEIYRWPARESLKTMLAMGWSLERTKEGGEAILHQ RENEKLRSISQSSQGNGYSPAPLDLSNVVLSRELQGMVEVMAENYHNIWAKKKKMELESK GGGSHPLLVPYDTLTAKEKSRDREKAQELFKFLQVNGIIISRGLNDMDLDASSMEKRFAF KFLKKILKYVDSAQEFIAHLEAIVTSGKTEKSPHDQEIKFFAKVLLPLVDQYFTNHCLYF LSSPTKTLSSSGYASNKEKEMVASLFCKLAALVRHRISIFGSDSTTMVSCLHILAQSLDT RTVMKSGSELVKAGLRAFFENAAEDLEKTSENLKLGKFTHSRTQIKGVSQNINYTTVALL PVLTSIFEHISQYQFGVDLLLGDVQVSCYRILCSLYSLGTGKNIYVERQRPALGECLASL AAAIPVAFLEPSLNHYNPLSVFNTKSARERAILGMPDTVEEMCPEIPQLDGLIKEINDLA ESGARYTEMPHVIEVILPMLCNYLSYWWERGSESVPESAGPFCTMITSEHLSIILGNILK IINNNLGIDEASWMKRIAVYAQPIISKARPDLLKTHFIPTLEKLKKKAIKIVMEEEQLKA DSKTDTQEAELLILDEFAVLCRDLYAFYPMLIRYVDNNRANWLKKPDADSDELFRMVAEV FILWCKSHNFKREEQNFVIQNEINNLAFLTGDTKSKMSKSGGQDQERKKSKRRGDLYSIQ TSLIVAALKKMLPIGLNMCTPGDQELISLAKTRYSHRDTDEEVKEHLRNNLHLQEKSDDP AVKWQLNLYKDILKSDEPTDPEKNVERVQRISAALYHLEQVEQPLRSKKAVWHKLLSKQR KRAVVACFRMAPLYNLPRHRSINLFLHGYQNYWIETEEYSFEEKLVQDLATPPKKDEEEE EDTEKKQPDPLHQIILYFSRNALTERSKLEDDPLYIAYSAMMAKSCQEEEEEEEEEKEKT FEEKEMEKQRTLYQQARLHDRGAAEMVLQMISASKGHTGPMVVETLKLGIAILNGGNTIV QQKMLDYLKEKKDAGFFQSLSGLMQSCSVLDLNAFERQNKAEGLGMVTEEGTLIVRERGE KVLQHDEFTRDLFRFLQLLCEGHNNDFQNYLRTQMGNTTTVNIIISTVDYLLRLQESISD FYWYYSGKDVIDESGQRNFSKALAVTKQIFNSLTEYIQGPCIGNQQSLAHSRLWDAVVGF LHVFANMQMKLSQDSAQIELLKELLDLLKDMVVMLLSLLEGNVVNGTIGKQMVDTLVESS SNVELILKFFDMFLKLKDLTNSDAFKEHDPDGKGIISKKEFQKSMEAQKQYIQSEIEFLL SCAEADENDMFNYVDFVERFHEPAKDIGFNVAVLLTNLSEHMPNDSRLQSLLEPAESVLN YFEPYLGRIEIMGGAKKIERVYFEISESSRMQWEKPQVKESKRQFIFDVVNEGGEQEKME LFVNFCEDTIFEMQLASQISETDSAERPEEEEEESCYVVDIGDDEEEEKSLESPSAFAMA CAAVKKNVTNFFKMVTVKNLRKQYRKVRKMTVKEMVKVFFSFFWILFVGMFQLFFTIVWG IFQILWSTVFGGGLVEGAKNIKVTKILGDMPDPTQFGIHDDVTEAEKAEGAEHGIRAELV QFVKGEKAETDIISDIFGIPTKKEGGSKHGHDAGLGDIAEILGSDIQSSLENTVRKKKGL QLSEIAKEAEAERKVEAEKADMEDGEKQDKAKEVLSEQLEEGKVKKKKRRHGQKIEKPEA VMANFFKALEIYQTKMLHYLARNFYNLRFLALFVAFAINFILLFYKVTEEPLDEVEEDSN LWNTFDEEEEEEGMVFFVLEESTGYMAPALRALAVIHTIISFVCVIGYYCLKVPLVVFKR EKEVARKLEFDGLYITEQPSEDDIKGQWDRLVINTPSFPNNYWDKFVKRKVINKYGDLYG AERIAELLGLDKNALDFSPVEESEPEEASLLSWLSSIDTKYHIWKLGVVFTDNSFLYLAW YTTMSILGHYNNFFFAAHLLDIAMGFKTLRTILSSVTHNGKQLVLTVGLLAVVVYLYTVV AFNFFRKFYNKSEDEDEPDMKCDDMMTCYLFHMYVGVRAGGGIGDEIEDPAGDPYEMYRI VFDITFFFFVIVILLAIIQGLIIDAFGELRDQQEQVREDMETKCFICGIGNDYFDTTPHG FETHTLQEHNLANYLFFLMYLINKDETEHTGQESFVWKMYQERCWDFFPAGDCFRKQYED QLG NT seq 14592 nt NT seq  +upstreamnt  +downstreamnt atggctgaagggggtgaaggaggggaagatgaaatacagttcctacgaactgatgacgaa gtagtacttcagtgtgttgccagcgttcacaaagaacaaaggaagttttgcttggcagct gagggacttgggaatcgcctgtgctttttggaaccaacatcagaagctaaatatgttcct ccggacctttgcatttgtaattttgtacttgaacagtccctgtctgtcagagcccttcaa gaaatgctggccaacacaggggataatgccagtgaaggggctgctcaaggtggtcacaga accctgctatatggtcatgctatactacttcgacattcgttcagtgaaatgtatttgact tgtttaacgtcatcaagatcccagacagataaacttgcatttgatgtgggactgagagaa aatgcagcaggtgaagcatgctggtggacaatacaccctgcatctaaacaaaggtcagaa ggagaaaaagttcgaataggtgatgatcttatcctggtcagtgtgtcttctgaaagatac ctgcatctctccatgtcaaatggaagtattcaggtggatgcctcctttatgcagacgctt tggaatgtacatcctacatgctcaggaagcaatattacagaagggtatcttcttggtggg catgtagtacgttttttccatggccatgatgagtgtttgacaattccatctacagatcag aatgattcacagcagaagaaagtactttatgaaactggaggagctggagttcgagcaagg tctttgtggagagtagaaccacttcgaataagttggagtggaagtaacatcaaatgggga caacctttccgtcttcgacatattacaacaggaatgtacttggctctgaatgatgatgaa ggacttgtaatgttagacagagaaaagtcagatacaacatctactgccttctgttttaga gcatcaaaggagctaaaagaaaaacaggattccactcttaaacgtgatattgatggaatg ggagtcccagaaataaagtacggtgattcagtctgttttgttcaacatgtggccagtgct ttatggttgacttataaagcgcaggatgctaaatcagcacgtttaggtctcttgaaaaga aaggttatattgcaccaagaaggccatatggatgatggtctaaccttacaaagatgtcag catgaagaatcccaggctgctcgaatcattcgcaatactacaagcttattcagccagttt ttaagtggaaacaacagaacactatcacccatcgccctgcctgttgaggagatggctcag actctgcaagacctgattacttacttccagcctcctgaagaagacttggaacacgaggat aaacaaagcaagcttcggtcactgaaaaacagacaaaatctattcaaagaagagggcatg ctggcactagttttgaattgcattgatcgtttaaatgactccaacagtgcagctcatttt gcagaaattgccagagaagaaaatggtaccacatggaaagaaattttaaatctcctttac aaattgttagctgccctcattcgtggcaacagaaacaattgtactcaattttccagtaac cttgattggctaataagtaaattggacagattagaatcttcctcaggtattttggaagtg ttgcactgtatcttgattgaaagcccagaagctttaaatataatagctgaggagcatata aaatctattatttcattgttggataaacatgggcgcaattacaaggttctcgatgtgctt tgctctctctgtgtctgtaatggagttgcggttcgtgccaatcaaaatttgatctgtgac aatctattgcctagaagagacttactcttgcaaacacgtttgattaatgatgtgacaagc ataaggccgaacatatttttgggtgttgctgagggctctgcacaatacaagaagtggtac tttgaattaataattgatcaggttgatccattcttgacggcagaacccacacatttacga gttggatgggcttctacttcaggttatgctccctatcctggaggaggagaaggatggggt ggcaatggtgttggcgatgacctatactcttacggttttgatggccttcatctgtggtct ggtcgagtacccagggctgtagcatctgtcaatcagcatttgttgtcatctgatgatgtg gttagctgctgcttggatttaggtgtgcccagcatttcattccgcattaatgggcagcct gtacaaggaatgtttgagaacttctgtactgaagggtttttcttccctgttgtaagctta tcagcaggtgtaaaagctcgtttcttattgggtggacgtcatggagagtttaaatttctc cctcctgctggctatgctccctgctatgaagccttgcttccaaaagagaagatgaaactg gaaccagtgaaagaatacaagagagattctgatggagtgagggatttgctgggtacaaca caattcctctcccaagcttcctttatcccttgtcctatagacaccagtcagattgctctt ccttttcatcttgaaaagatcagggacaaactagctgaaaatatccatgaactgtgggga atgaataaaatagaactgggctggacatatggcaagatacgggatgataataaaaggcat catccttgtcttgtagaattctcaaaattacctgagacagagaagaattataatctgcaa atgtcaactgaaactctcaaaacccttttggcccttgggtgtcacattgttcatgctaat ccagcagcagaagaagatcttaaaaaagtcaagcttcctaaaaattacatgatgtcaaat ggatataaacctgcccctcttgatctttctgaagtgaaattgttaccttctcaagaattc ctagttgacaaactagcagaaaatgcacacaacgtctgggcaaaagacagaataaagcaa ggatggacctatggcattcaacaggatcttaagaacaaacgtaatcctcggctagtgcca tatgcgttattagatgaacgtactaaaaaatcgaacagagatagcctccgtgaagctgtt agaacatttgcaggctatggttatagtgttgagccacctgaccaagaaatagctgatcaa acaacggaaaaagtcagcattgacaagatacgctttttcagagtcgaacagtcttatgca gtgaagtctggaaagtggtactttgaatttgaagctgtgacaggtggagacatgcgtgtt ggctgggccaggccaggctgtcgacctgacatagaactgggagctgatgaccaagcattt gtttttgaaggaagcaaaggccagcgttggcatcaaggcagtggattctttggacgaagt tggcaaccaggagatgtggttggttgcatgataaacttggatgacaaatcaattatcttt actttgaatggagaattgcttataaccagtaaaggttcagaacttgcgtttgctgacttc ggaatagaaagtggttttgttccaatttgcgcactgggtctgtctcagattggacgtatg aaccttggaatggatgccagtacattcaagtattatacaatgtgtggccttcaagaaggt tttgaaccttttgcagtaaatatgaaccgagatgtcgctatgtggtttagtaaacgctta ccaacatttgtcaatgtgccaaaaaatcatcctcacatagagatatggagaattgatgga accattgagagtccacctcgattaaaagttactcacaaaacatttggcacacagaacagc agttcagacatgatatattgtcgtttgagtatgcctgttgagttccgttcatcattcaac tttggcatgggtgtggaaaatgcctcatctgatgttttccaaaaacgaaaacacagccaa gaagtttctgttccttctactacgtatttttattcgttgcggatatttgctgggcaagac ccatcctgtgtctgggttggctgggtaacaccagactatcatttttacagtgaaaatttt gacctaaataaaaattgtacagtgacggttactttaggtgatgagagaggcagggttcat gaaagtgtgaagcgcagtaattgctatatggtttggggaggagatataacttctaattcc cagagatcaggtcgtagcaatgttgatttagaaattggatgctttgttgacctagctact ggaatgttgtcattcacagccaatggaaaagagcttggcacttgttatcaggttgaacca aacacaaaactttttccagcaacttttgtacagcctacgagcactaacttggttcagttt gaacttggtaaattaaagaataccatgcctttatcagcagcaatttttaaaagtgaggaa agaaatcctgttcctcagtgtccccctcgccttgatgtgcaaacaattacacctgtttta tggagcaggatgcctaacagctttcttaaagtagaaaccgagcgtgtcagtgaacgtcat ggatgggttgtgcagtgtttggaacctctgcagatgatggcacttcatatcccagaggaa aacagatgcgttgatattttggaactatgtgaacaagaagatttgatgaagtttcactat cacactttaaaactctatagctcagtttgtgctctaggtaacactagagttgcttatgca ctttgtagccatgtggatgtatctcagttattttacacaatagataatcaatatttacct ggactcctacgttctggattctatgacttgttgattagtatacatttggagcatgccaaa caagccaagctcatgatgaacaatgaatttatcattccagttacagaggaaactcgaact attagattatatcccgatgaaacaaagaagcatggtttacctggagtagggcttagcact tgtctgaaaccaggctttcatttttctgctccttgctttattgtgaccagtgaagaacat cagacatccagcccagagataccccttgatacacttaaatccaaagccataagtatgcta acagaggcagtacagtgtagtggtgctcatatacgagaccctgttggaggacacattgca ttccagtttgttcctgttcttaaactaatagcaacactgctcataatgggggtttttgat gatgatgatgtgaagcaggtgttaatcctcattgatccaaatgtatttggagatcacaag gaagaaacagaagaggggacagaaaaggaagaagttacacaagttgaagaaaaagctgta gaagctggagaaaaagcaataaaagaaaccaaagctcctacaacaggcttgttgcagaca agattaccagaatctgttaagcttcagatgtgccatttactcaattatttctgtgactgt gagctgcaacatagagtggaagcaattgtgtcatttgcagaccgttatgtatcaaaatta cagtataatcagaaatacaggtataatgaactcatgcaagccttgaacatgtctgcagct ttgactgccaagaagactaaagaatttcggtctcctccacaagaacagattaatatgttg ctgaattttcaactgggagaggattgtccatgtccagaggagattcgggatgagctgtat gacttccatgatgatcttctaattcactgtggtattccactagaagaggaagaagaggaa gaggaagattccaccttgactggcaaactccgttcgttaatatacaaaatcaaaggtcca ccaaaagcagaaaaagtagagcctagggaagaagaagagaaatcacctactacactgaag gaactcatatcccagactatggtacgctggtctcaggaagatcagattcaagatccagaa ttggttcggattatgtataccctccttcgtaggcaatatgacagcattggtgagctactt caagctctgaggaaagcatacactattagtgctacctctgtgaaggatacaattaatctg cttgctgcactgggccagattcgctcacttctcagtgtcagaatgggaaaagaggaggaa ttgctaatgattaatggattaggggatataatgaacaacaaggtgttttatcagcatcct aacttaatgagagtcttgggcatgcatgagacagttatggatgtgatggtgaatgtgctt ggaggagataagtctcagatcgtttttcctaagatggtggcaagctgttgtcgattccta tgctacttctgtcgaattagtcgtcaaaaccaaaaagccatgtttgagcatcttagttac ttactggaaaacagcagcgttgggctggcatttccttcaatgagaggttcaacaccacta gatgttgcagcagcctccgtaatggacaacaatgagcttgcactagcactggaagagcca gatctggataaagttgttacttatttggctggttgcggcctgcagagttgtccagtattg ctagcgaaaggatatccagacattggatggaatccaatagagggtgaacgttacctgtca ttcttaagatttgcagtttttgttaacagtgaaagtgttgaagaaaatgcaagtgttgtt gtcaagctccttattcgacggccagagtgctttggaccagaccttagaggagaaggagga aatggtttgctggcagctatgcaagaagctatcagaatctcagagaatccttctcgtgac cttccctcacaaggatataggagagaaggtgatgaggaggaggaagaggaggagattgtg cacatgggcaatgcaatcatgtcattttactcggctctcatagatttacttggacgctgt gcaccagaaatgcatcttattcaaagtggaaaaggtgaagctattcgaatcaggtcaatc ctccgatctctagtgccaactgaagatttggttggaattataagtataccactaaagctg tcaacagttaacaaagatggcacagtaaatgagccagacatgtctgcaaatttctgtcct gatcataaagcaccaatggtactcttcttggaccgtgtatatggtattaaggaccaaagc ttcctccttcacctattggaagttggatttttaccagatttaagagcttctgcctctctg gatacagttactctaagtaccacagaggcagctctcgcactaaatagatatatttgttca gctgtgtttccgttactcaaaagatgtgctcccctcttttctggaacagagcatcatgct tctctggttgactccatgcttcacacaatatataggttatccaaaggacgttcccttaca aaagcacaacgagacactattgaagaatgcctgcttgctatttgccaccacttacgtccc tctatgctacaacagctgttgagaaggctagtttttgatgtaccgctactcaatgagtac tgtaaaatgcctctcaagcttctgacaaatcactatgaacagtgctggaaatactattgt ctaccttcaggaatgggaagctatggaattgcagcagaagaagaattacatttaactgag aaacttttctggggaatatttgattccttgtctcataagaagtatgatccagagctcttt cgaatggccttgccttgtttaagtgctatagctggtgccttgcctcctgattatttagat acacgaattagatcaactttggaaaagcagacttcagtggatccagaaggaaattttgat cccaaacctgtcagtacagcaaaccttgtacttccggaaaagttggagtatattgtcagc aagtatgctgaacattcccatgataagtgggcctttgataagactaataatggatggaaa tacggtgtttcactggatgaaaatacaaagactcacccattaataagacctttcaaaact ttaactgaaaaggaaaaagaaatttatcgttggcctgctagagaatcactgaaaaccatg ttggccatgggatggagcctagaaaggaccaaagaaggaggagaagcaatattacatcag cgtgaaaatgaaaagctccgtagcatatctcagtcgagccagggaaatggatatagccca gcaccacttgatctctctaatgtggtgctttctagggagcttcagggaatggttgaggta atggcagaaaactaccataatatatgggccaaaaagaagaaaatggagttggaaagcaaa ggtggaggtagtcatcctttattggtaccttatgacacattgacagccaaggagaaatca cgggaccgtgaaaaggcacaggagctgtttaaattccttcaagtgaatggtataatcata tctcggggtctgaatgacatggatttggatgcttcatccatggaaaagaggtttgccttt aagtttctgaagaaaattttaaaatatgttgactctgctcaagagttcattgcacatttg gaagccattgtaaccagtggaaaaactgaaaaatctccacatgaccaagaaataaaattc tttgcgaaagttcttttaccattagttgatcagtactttacaaatcactgcctgtacttc ctgtcttctccaacaaaaacactcagtagcagtggatatgcatcaaataaggaaaaggaa atggtagcaagcctgttctgcaaactagctgctcttgttagacataggatctcaattttt ggtagtgattctacaacaatggttagctgcctgcacatcttagctcagtctcttgacact cgaactgttatgaaatcgggatctgagctagttaaagctggattacgtgccttttttgaa aatgcagctgaagatctggaaaaaacttcagaaaatcttaaacttggaaaatttacccat tcacgaacacaaatcaagggtgtttcacagaatatcaattatactacagtagcattgtta cctgtcttgacatcaatttttgagcatatttcacagtatcagtttggagttgatttactt ttgggtgatgtacaagtttcatgttatagaattctttgtagcctctattcccttgggact gggaagaacatctatgttgaaaggcagcgccctgcacttggtgagtgcttagcatctctt gcggcagccattccggtagcatttcttgaaccttctctcaaccattacaacccattgtct gtcttcaacacaaaaagtgcaagagaaagagcaattttaggtatgcctgatacagtagag gagatgtgtccagagatcccccagttggatggactaataaaggaaattaatgatttagca gagtctggagcaaggtatactgaaatgcctcatgtaattgaggttatcttacccatgcta tgcaactatttgtcctactggtgggaacgagggtccgagagtgttcctgaaagtgctggg cctttctgtacaatgataacatctgaacatctaagcatcattctgggaaacattctgaaa atcattaacaacaatctgggaatagatgaagcatcttggatgaagagaattgcagtttat gctcagcctatcatcagcaaagccagaccagatctgctgaaaactcactttattccaaca cttgagaaattgaagaagaaagctataaagattgtgatggaagaggagcaactgaaagca gacagtaaaactgacacccaggaagctgagctactcattctcgatgaatttgctgttctt tgtagagacctctacgccttctatccaatgttgatacgttatgtagacaacaacagagcc aattggctaaagaaaccagatgcagactctgatgaactcttccgaatggtagctgaagtg tttatcctgtggtgtaaatcacataatttcaaaagagaagaacaaaattttgtgattcag aatgaaatcaacaacttggcatttttaacaggagataccaaaagcaagatgtctaaatct ggaggacaagatcaagaaagaaagaagtcaaaacgtagaggggatttgtactccatacaa acatccttgattgtagctgcacttaaaaagatgcttcctattggcttgaatatgtgtact cctggagatcaagagctcatctctttggctaagactagatacagccatagggacactgat gaagaagtcaaagaacatttacgtaacaacttacatttgcaggaaaagtctgatgatcca gctgtgaaatggcagttaaatctgtataaagacattttgaaaagtgatgagcctactgac cctgagaaaaatgtggaacgtgtgcagaggatatcagctgctctgtatcatctggagcag gttgaacaaccgctgagatcaaagaaagctgtttggcataaactcctgtcaaaacaacgc aaaagggctgttgttgcttgttttagaatggcaccattgtacaacctgcccaggcaccgt tctattaacctcttcctccatggctatcagaactattggatagaaacagaggaatattca tttgaggagaaactagttcaggatttggctacacctccaaaaaaagatgaagaagaagag gaagatactgagaaaaaacagcctgatccacttcatcagattatcctttattttagtcgc aatgctctcacagagaggagcaaactagaagatgatcctttatatatcgcctattctgcc atgatggcaaagagctgtcaggaagaagaggaggaagaagaggaagaaaaagagaagaca tttgaggagaaagaaatggaaaagcagagaactctttaccagcaagctcgcttgcatgat cgtggagctgctgagatggtccttcagatgattagtgcaagcaaaggtcatacaggaccc atggttgttgaaacattaaaacttggtattgctattctaaatggtgggaataccatagtt caacagaaaatgttagactacctgaaggagaaaaaggatgctggattctttcaaagtctc tctggcttgatgcagtcctgcagtgttcttgacttgaatgcgtttgagagacaaaataaa gcagaaggcctgggaatggttactgaagaaggaactctcatcgttcgtgagcgtggtgaa aaagtgttgcagcatgatgaatttactcgagatctatttagatttttacaactgctctgt gaagggcataacaatgattttcaaaattacctacgtactcagatgggcaacaccacaaca gtgaatattatcattagtactgttgactatctcttgcgtcttcaggaatcaatcagtgac ttttattggtactattcaggaaaagatgtcattgatgaatcaggacaacgtaacttctct aaagctttggctgtcaccaaacaaatattcaattcccttacagaatatattcagggccct tgcataggtaaccaacaaagtctggctcatagtaggctgtgggatgcagttgttggcttt cttcatgtctttgccaatatgcagatgaaactttcacaggactctgctcagattgaattg cttaaagaactgctagatctactaaaggatatggtagtcatgctgttgtcactgcttgaa ggtaatgttgtaaacggaacgatcggaaaacaaatggtcgatacgcttgtagaatcatct agcaatgtagaattgattttgaaattttttgacatgttcctcaaattaaaagatctaact aactcagatgctttcaaagaacatgacccagatggtaaaggcataatttcaaaaaaggaa ttccagaagtcaatggaggctcaaaaacaatatatacagtcagagattgaattcctgcta tcctgtgcagaagctgatgaaaatgacatgtttaactatgtcgattttgtggaaagattc catgaaccagccaaagacattggatttaatgtagcagtattgctaacaaacctttcagaa cacatgcctaacgattcacgccttcagagtttacttgaacctgcagaaagtgttcttaat tactttgaaccataccttggccgtattgaaataatgggtggagccaagaaaatagaaaga gtttactttgaaatcagtgagtccagtagaatgcagtgggagaagccacaggtgaaggaa tccaaaaggcagttcatatttgatgttgtaaatgaaggtggagagcaagaaaagatggaa ctctttgtgaatttctgtgaagacacaatctttgaaatgcagttagcatcacagatctct gaaactgattcagctgagaggcctgaggaagaggaagaagagtcttgctatgttgtagat attggagatgatgaggaagaagaaaagtccctggaatctccttcagcttttgcaatggcc tgtgctgcagtgaagaagaatgttaccaacttttttaaaatggtcactgtgaagaaccta agaaaacagtacaggaaagttagaaagatgacagtaaaagagatggtgaaagtgtttttc tcctttttctggatcctatttgtagggatgttccaactcttctttactatagtgtgggga attttccagattctttggagcactgtatttgggggtggcctggttgaaggagccaaaaac attaaagtcactaaaatattaggggacatgcctgacccaacacagtttggaatccatgat gatgttacagaagcagaaaaagctgaaggtgctgagcatggcattagagctgaacttgtc cagtttgtaaagggcgaaaaggcagaaactgacattatctctgatatttttggcattcct accaaaaaagaaggtggctcaaaacatggtcatgatgctggacttggggatattgcagaa atacttggttctgatatccagtcttctttggaaaacacagttcgtaagaaaaaaggatta cagctatctgaaattgcaaaagaagctgaagcagaaagaaaagtggaagctgagaaggct gacatggaagatggtgagaaacaagataaagcaaaggaagtactgtctgagcagctggaa gagggaaaggtgaagaaaaagaagagaaggcatggacaaaaaattgagaaacctgaggct gttatggctaacttcttcaaagctttggaaatttatcaaaccaaaatgcttcactaccta gcaagaaatttttataacttaaggtttcttgctctatttgttgcatttgctatcaacttt attctactattttacaaggtgacagaagagccacttgatgaggtagaggaggactctaat ctctggaacacttttgatgaagaggaagaggaggaaggcatggtgttttttgttttagaa gaaagtacaggttacatggcacctgctctcagagcattggcagttattcataccatcatc tcctttgtctgtgtgattggatactattgcttaaaggtccctctggttgtattcaagaga gaaaaggaagtagctaggaagctggaatttgatggattatacataactgaacagccatct gaagatgatattaaaggacaatgggatcgcctggttataaacacaccgtcctttcctaac aattactgggacaaatttgtaaaacggaaggttattaacaagtacggagacttatatgga gcagagcgcatagcagaacttttgggtttggacaaaaatgcccttgattttagtccagtg gaagagagtgaaccagaagaggcatctcttctatcatggttaagctccattgataccaag taccacatttggaagctcggtgttgttttcactgataattcatttttatacttagcttgg tacacaactatgtctatccttgggcactacaacaacttcttctttgctgctcatctgctg gatattgctatgggtttcaagactttgcgaaccattctgtcttcagtcactcacaatggc aaacagcttgtgcttactgtaggactcctggctgtagtagtgtatctttacaccgttgtg gcattcaactttttccgcaaattctacaacaaaagtgaagatgaagatgaaccagacatg aaatgtgatgacatgatgacgtgttacctgttccacatgtatgtgggtgtaagagctggc ggtggcattggggatgaaattgaggatcctgcaggagacccttatgaaatgtatcgaatt gtctttgacatcacatttttcttctttgtcattgttatcctactggccattattcaaggt ctgatcattgatgcttttggtgaattaagagaccagcaagaacaagtgagagaagatatg gagaccaaatgttttatttgtggaattggcaacgactattttgacacaaccccacatggc tttgaaacacatactttgcaagagcacaacttggcaaactacctgttctttttaatgtat ctcataaacaaggatgaaactgagcatactggccaggaatcatttgtgtggaagatgtac caagaaagatgttgggattttttcccagcaggagactgcttccggaaacagtatgaggat caacttggctaa

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