Amycolatopsis cynarae: ORV05_08855
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Entry
ORV05_08855 CDS
T09969
Symbol
pdhA
Name
(GenBank) pyruvate dehydrogenase (acetyl-transferring) E1 component subunit alpha
KO
K00161
pyruvate dehydrogenase E1 component subunit alpha [EC:
1.2.4.1
]
Organism
acyn
Amycolatopsis cynarae
Pathway
acyn00010
Glycolysis / Gluconeogenesis
acyn00020
Citrate cycle (TCA cycle)
acyn00620
Pyruvate metabolism
acyn00785
Lipoic acid metabolism
acyn01100
Metabolic pathways
acyn01110
Biosynthesis of secondary metabolites
acyn01120
Microbial metabolism in diverse environments
acyn01200
Carbon metabolism
acyn01210
2-Oxocarboxylic acid metabolism
Module
acyn_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
acyn00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
ORV05_08855 (pdhA)
00020 Citrate cycle (TCA cycle)
ORV05_08855 (pdhA)
00620 Pyruvate metabolism
ORV05_08855 (pdhA)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
ORV05_08855 (pdhA)
Enzymes [BR:
acyn01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
ORV05_08855 (pdhA)
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Motif
Pfam:
E1_dh
TPP_enzyme_C
Motif
Other DBs
NCBI-ProteinID:
WAL67863
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Position
1828990..1830072
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AA seq
360 aa
AA seq
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MAEPSREPVSGSAATSDRGRSEDAEVLRRYYRQMMVIRVFEQRAAEMYTKAKIGGYCHLN
LGEEATVVGLTAALRAGDYLFTTYREHGYALARGADPGRVMAELFGRATGLSGGRGGSMH
LFDAQHRLLGGYGIVGGQIPPATGAALALAYRHGPSPHGDAVMCLLGDAATNIGAFHESL
NLAAVWRLPIVYVIVNNQLGMGTPVEAAAGEPELFRRGCSYRIPGQRVDGNDVLAVREAA
RDALDRARGEHQPMLVETVSYRLRGHSVVDPARYRSDADNRRLRDLDPVPAFRARLIDDA
VLDPGSAARIDSEAEQIVAEAVEVADHAPDPDGETLFDHVYATPVANTPQGRPGDPAVTP
NT seq
1083 nt
NT seq
+upstream
nt +downstream
nt
atggccgagccctctcgggaaccggtgagcggctccgcggccaccagcgaccgcggacga
tccgaggacgcggaagtgctgcgccgctactaccggcagatgatggtgatccgggtgttc
gagcagcgcgccgccgagatgtacacgaaggcgaagatcggcggctactgccacctcaac
ctcggcgaggaagccaccgtcgtcggtctgacggccgccctgcgagcgggcgactacctg
ttcaccacctaccgggagcacggctacgccctggcccgcggtgccgaccccgggcgggtc
atggccgaactgttcggccgcgccacggggctgtcgggcgggcggggcggctcgatgcac
ctgttcgacgcgcagcaccgcctgttgggcggttacggcatcgtcggcggccagatcccg
cccgccacgggtgccgcgctcgccctggcctaccggcacggccccagcccccacggcgac
gcggtgatgtgcctgctgggtgatgcggccacgaacatcggggccttccacgagtcgctc
aacctcgccgccgtctggcggctgccgatcgtgtacgtgatcgtcaacaaccagctcggc
atgggtaccccggtcgaggccgccgccggtgagcccgaactgttccggcggggctgttcc
taccgcatccccgggcagcgggtggacggcaacgacgtgctcgccgtccgcgaggccgcc
cgtgacgcgctggaccgggcccgcggcgagcaccagccgatgctggtggagacggtcagc
taccggttgcgcgggcactcggtggtcgacccggcccgctaccgcagcgacgccgacaac
cggcgactccgggacctggacccggtgcccgcgttccgcgcccggctgatcgacgacgcc
gtcctcgatcccgggagtgcggcgcggatcgacagcgaggccgagcagatcgtcgccgag
gccgtcgaggtcgccgaccacgcaccggacccggacggggaaacactgttcgaccacgtg
tacgccaccccggtcgccaacaccccccagggcaggcccggtgacccggcggtgactccg
tga
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