Amycolatopsis cynarae: ORV05_25750
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Entry
ORV05_25750 CDS
T09969
Symbol
ilvD
Name
(GenBank) dihydroxy-acid dehydratase
KO
K01687
dihydroxy-acid dehydratase [EC:
4.2.1.9
]
Organism
acyn
Amycolatopsis cynarae
Pathway
acyn00290
Valine, leucine and isoleucine biosynthesis
acyn00770
Pantothenate and CoA biosynthesis
acyn01100
Metabolic pathways
acyn01110
Biosynthesis of secondary metabolites
acyn01210
2-Oxocarboxylic acid metabolism
acyn01230
Biosynthesis of amino acids
Module
acyn_M00019
Valine/isoleucine biosynthesis, pyruvate => valine / 2-oxobutanoate => isoleucine
acyn_M00570
Isoleucine biosynthesis, threonine => 2-oxobutanoate => isoleucine
Brite
KEGG Orthology (KO) [BR:
acyn00001
]
09100 Metabolism
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
ORV05_25750 (ilvD)
09108 Metabolism of cofactors and vitamins
00770 Pantothenate and CoA biosynthesis
ORV05_25750 (ilvD)
Enzymes [BR:
acyn01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.9 dihydroxy-acid dehydratase
ORV05_25750 (ilvD)
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Motif
Pfam:
ILVD_EDD_N
ILV_EDD_C
Motif
Other DBs
NCBI-ProteinID:
WAL64351
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Position
5387765..5389609
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AA seq
614 aa
AA seq
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MPQLRSRTTTHGRNAAGARSLWRATGMTDSDFGKPIVAIANSYTQFVPGHVHLKNLGEIV
AEAVAEAGGVAREFHTIAVDDGIAMGHGGMLYSLPSREIIADSVEYMVNAHQADALVCIS
NCDKITPGMLNAALRLNIPTVFVSGGPMEAGKAVVVDGVAHAPTDLITTISASANAAIDE
EGLGVVERSACPTCGSCSGMFTANSMNCLTEALGLSLPGNGSTLATHAARRALFTEAGRT
VVELAKRWYGEDDESALPRSIANKKAFENAMALDMAMGGSTNTVLHVLAAAQEGEVDFTI
DDIDAIGRRVPCLSKVSPNSDYHMEDVHRAGGIPAILGELNRAGLLNKDVHAVHSPSLEA
WLSTWDIRAESPSAEAVELFHAAPGGVRTTEAFSTSNRWSSLDTDAAGGCIRDIEHAYTA
DGGLAILRGNLAERGAVIKSAGIDESLWVFQGPARVVESQEEAVSVILGKKIQPGEVLVV
RYEGPAGGPGMQEMLHPTAFLKGAGLGKKCALITDGRFSGGSSGISVGHISPEAASGGVI
GLVQDGDQILIDVHQRRLELLVDEEVLAERRSKMETSERPWQPVDRQRPVTAALRAYARM
ATSADTGAVRDVNR
NT seq
1845 nt
NT seq
+upstream
nt +downstream
nt
atgcctcagttgcgttcccgaaccaccacccacggccgcaatgccgcgggcgcccgctcc
ctgtggcgggccaccggcatgaccgacagcgacttcggtaagccgatcgtggcgatcgcc
aactcctacacccagttcgtgcccggccacgtacacctcaagaacctcggcgagatcgtg
gccgaagcggtggccgaggccggcggggtggcccgggagttccacacgatcgcggtggac
gacgggatcgccatgggccacggcggcatgctctactcgctgccctcgcgcgagatcatc
gccgactcggtggagtacatggtcaacgcgcaccaggcggacgcgctggtgtgcatctcc
aactgcgacaagatcacgccgggcatgctcaacgccgcactgcggctcaacatccccacc
gtgttcgtgtccggcgggccgatggaggcgggcaaggcggtcgtggtcgacggggtcgcg
cacgcaccgaccgacctgatcaccacgatctcggcctcggccaacgccgcgatcgacgag
gagggcctcggcgtcgtggagcgctcggcctgcccgacctgcggctcctgctcgggcatg
ttcaccgcgaactcgatgaactgcctcaccgaggcgctgggcctgtcgctgcccgggaac
ggctccaccctggccacgcacgccgcccgccgcgcgctgttcaccgaagcgggccgcacc
gtggtggaactggccaagcgctggtacggcgaggacgacgagagcgcgctgccccgctcc
atcgcgaacaagaaggcgttcgagaacgccatggcgctggacatggccatgggcggttcg
accaacaccgtgctgcacgtcctcgccgccgcgcaggagggcgaggtcgacttcaccatc
gacgacatcgacgcgatcggccgccgggtgccctgcctgtccaaggtgtcccccaactcg
gactaccacatggaggacgtgcaccgggccggtggcatcccggcgatcctcggtgagctg
aaccgcgccggcctgctgaacaaggacgtccacgcggtgcactcccccagcctcgaggcg
tggctgtccacttgggacatccgggccgagtcgccctccgccgaggccgtggagctgttc
cacgcggcgccgggcggggtccgcaccaccgaggcgttctccacctcgaaccgctggtcc
tctttggacaccgacgcggcgggtggctgcatccgcgacatcgaacacgcgtacaccgcc
gacggcggcctggccatcctgcgcggcaacctcgccgagcgcggcgcggtgatcaagtcc
gcgggcatcgacgagtcgctgtgggtcttccagggccccgcgcgggtcgtggagagccag
gaagaggccgtctcggtcatcctcggcaagaagatccagccgggtgaggtgctcgtggtc
cgctacgaaggccccgcgggcggccccggcatgcaggagatgctgcacccgacggcgttc
ctcaagggcgcgggcctcggcaagaagtgcgcgctgatcaccgacggccggttctccggt
gggtcgtcgggcatctcggtcgggcacatctcccccgaggccgcttccggcggcgtgatc
ggcctggtgcaggacggggaccagatcctcatcgacgtgcaccagcgcaggctcgaactg
ctcgtcgacgaggaggtgctggccgagcggcggtcgaagatggagacgagcgagcggccg
tggcagccggtcgaccggcagcggccggtcaccgccgcgctgcgggcctacgcccggatg
gcgacctcggccgacaccggcgccgtccgcgacgtcaaccgctaa
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