Anopheles darlingi (American malaria mosquito): 125952508
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Entry
125952508 CDS
T11379
Name
(RefSeq) 2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial
KO
K00166
2-oxoisovalerate dehydrogenase E1 component subunit alpha [EC:
1.2.4.4
]
Organism
adar Anopheles darlingi (American malaria mosquito)
Pathway
adar00280
Valine, leucine and isoleucine degradation
adar00640
Propanoate metabolism
adar00785
Lipoic acid metabolism
adar01100
Metabolic pathways
adar01210
2-Oxocarboxylic acid metabolism
Module
adar_M00036
Leucine degradation, leucine => acetoacetate + acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
adar00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00640 Propanoate metabolism
125952508
09105 Amino acid metabolism
00280 Valine, leucine and isoleucine degradation
125952508
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
125952508
Enzymes [BR:
adar01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.4 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)
125952508
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NCBI-GeneID:
125952508
NCBI-ProteinID:
XP_049537968
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Position
2:complement(12461491..12463134)
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AA seq
437 aa
AA seq
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MSFVRTAVRSALARRSAFFRSVKHLSTDAAQPQQHAAGAGGAKFPGAQQASFVTAPKLAL
PETMEPLSIYRVMNSEGVIEDESQDPKLDQATVRKMFRDMVLLNTMDKILYESQRQGRIS
FYMTNFGEEASHIGSAAALSIEDWVYGQYREAGVLVWRGFTISDFINQCYGNAEDQGKGR
QMPVHYGSRKLNFVTISSPLGTQIPQAAGAAYAFKLQPNNQRCVVTYFGEGAASEGDTHA
AFNFAATLDCPVIFFCRNNGFAISTPSAEQYRGDGIAGRASGYGMAALRFDGTDVFATYN
ATKLAREYVLRENKPIVLEAMAYRIGHHSTSDDSTAYRPAEELEVWNTVEHPITKLKHYM
IRRGWFNEEEENEFVKSVRKQVLSQINQSERIPKPNWREMFQDVYQDMPNHLKEQMREME
EHVAKHQEHYPLKDYKQ
NT seq
1314 nt
NT seq
+upstream
nt +downstream
nt
atgtcgtttgtccgtaccgccgtacgcagcgccctggccagacggtcagccttcttccga
tcggtaaagcacctatcgaccgatgccgcgcaaccgcaacagcacgcagccggagcaggc
ggtgccaagtttccgggcgctcagcaagcctcgttcgtcacggcaccgaagctggcgtta
ccggaaaccatggaaccgttgtcgatctatcgcgtgatgaacagcgagggtgtgatcgag
gatgaatcgcaggatcccaagctcgatcaggcgacggtgcgcaaaatgttccgtgatatg
gtgctgctgaacacgatggacaaaatcctgtacgaatcgcaacgccagggacgcatttcg
ttctacatgaccaactttggcgaggaagcgagccatatcggcagtgccgctgccctcagt
atcgaagattgggtatacggacaataccgtgaggcgggtgtgttggtatggcgcggattc
accatttcggattttatcaaccagtgctacggtaatgccgaggatcagggcaaaggacgc
cagatgccggtacattatggttcgcggaagctcaactttgtgacgatctcgtcaccgctc
ggtacgcagatcccacaagcggccggtgccgcgtacgccttcaagctgcaacccaacaac
caacggtgcgtggtcacgtacttcggcgaaggcgccgcctccgagggcgatactcatgcg
gcattcaattttgcggccacgctggattgtccagtgatcttcttctgccgtaacaacggt
ttcgccatctcgacaccctcggcagagcagtaccgtggtgatggtattgccggacgcgcc
agtggctacggtatggcggcattgcggttcgacggaacggacgtgtttgcaacgtataac
gccaccaaactggcgcgtgagtatgtgctgcgcgagaacaaaccgatcgtactggaggcg
atggcctatcgtatcgggcatcattcgacatcggacgatagtaccgcctaccggccagcg
gaagagctggaggtgtggaacacggtggagcatccgatcaccaagctaaaacactacatg
atccggcgcggttggttcaatgaggaggaagagaatgagtttgtcaagtccgtccgcaag
caggtgctctcgcagatcaaccaatcggaacgcattccgaagcccaattggcgggaaatg
ttccaggatgtgtaccaggatatgccgaaccatctgaaagagcagatgcgcgagatggag
gagcacgtagccaagcatcaggagcactatccgttgaaggattacaagcagtag
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