Arcobacter defluvii: ADFLV_0608
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Entry
ADFLV_0608 CDS
T06891
Symbol
leuA
Name
(GenBank) 2-isopropylmalate synthase, bacterial type
KO
K01649
2-isopropylmalate synthase [EC:
2.3.3.13
]
Organism
adz
Arcobacter defluvii
Pathway
adz00290
Valine, leucine and isoleucine biosynthesis
adz00620
Pyruvate metabolism
adz01100
Metabolic pathways
adz01110
Biosynthesis of secondary metabolites
adz01210
2-Oxocarboxylic acid metabolism
adz01230
Biosynthesis of amino acids
Module
adz_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
adz00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
ADFLV_0608 (leuA)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
ADFLV_0608 (leuA)
Enzymes [BR:
adz01000
]
2. Transferases
2.3 Acyltransferases
2.3.3 Acyl groups converted into alkyl groups on transfer
2.3.3.13 2-isopropylmalate synthase
ADFLV_0608 (leuA)
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GFIT
Motif
Pfam:
HMGL-like
HCS_D2
LeuA_dimer
IPMS_D2
NADH_4Fe-4S
EFhand_Ca_insen
Motif
Other DBs
NCBI-ProteinID:
QKF76666
UniProt:
A0AAE7BEX8
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Position
594083..595636
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AA seq
517 aa
AA seq
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MDKNKIIVFDTTLRDGEQSPGCSMNTEEKIKVALQLEKLGVDVIEAGFAAASPGDFDAVS
RIAQIIKNSSICSLARAVENDIKQAGLAVKEAPKHRIHTFIATSPIHMKYKLKMSEEEVI
KRAIHAVQYAKTFVDDVEFSLEDAGRSEISFMKEVMDAVISAGVRTINLPDTVGYRLPTE
LGAMVKELSDFAGDRAIISVHNHNDLGLATANTLAAVMNGARQIEVTINGLGERAGNSAL
EEAVMAIKTRRDAFGDLYTTINTPEIYATSRLVATITGVEPQQNKAIVGKNAFSHESGIH
QDGVLKHQETYEIMRPEDVGVIKDSTLILGKHSGRAAFKDKIAQLGFDKVSDEELNSVFE
RFKALADKKKEITDDDVRMLITDESLNHDKTYDLIGLQISDCTTGVPTAAVAIKYKDEII
KDAAIGDGTMDAIFKTIDRITGYAGELKDYKVISVTEGKDALAKVTTRVSFDSTSPAFVG
HGLSIDTMLATAKAYLGALNSYLSQKERLSKKSEHQV
NT seq
1554 nt
NT seq
+upstream
nt +downstream
nt
atggataaaaataaaattattgtatttgatacaacattaagagatggggaacaaagtcct
ggttgttctatgaacacagaagaaaaaataaaagtggctttgcaattagagaaattaggt
gttgatgtaatagaagctggatttgcagcagcaagtcctggagattttgatgcagttagt
agaatagcacaaataattaaaaattcaagtatttgttctttagcaagagcagttgaaaat
gatataaaacaagctggattagcagtaaaagaagctccaaaacatagaatccatacattt
attgcaacatcaccaattcatatgaaatataaattaaaaatgagcgaagaagaagttatt
aaaagagcaattcatgcagtacaatatgcgaaaacatttgtggatgatgttgaattttct
ttagaagatgcaggaagaagtgaaatttcttttatgaaagaagtaatggatgctgtcatt
agtgcaggtgtaagaactataaatttacctgatacggtaggatatagattacctacagaa
ttaggcgcaatggttaaagaattaagtgattttgcaggcgatagagcaataatttcagtt
cataatcataatgatttaggattagcaactgcaaatactttagccgcagttatgaatggt
gcaagacaaattgaagtaacaattaatggattaggagaaagagctggaaattcagcttta
gaagaagcagttatggctattaaaactagacgtgatgcttttggagatttatatacaact
attaatactcctgaaatttatgcaacttcaagattagttgcaacaataactggtgtagaa
ccacaacaaaacaaagctatagttggtaaaaatgcattttctcatgaaagtggaatccat
caagatggtgtattaaaacatcaagaaacttatgaaattatgagaccagaagatgtaggt
gttataaaagatagtactttaattttaggtaaacattcaggtcgagctgcatttaaagat
aaaattgcacaattaggatttgataaagtaagtgatgaagagttaaattctgtatttgaa
agattcaaagcattagctgataagaaaaaagagattacagatgatgatgtaagaatgtta
attactgatgaatcattaaatcatgataaaacttatgatttaattggattacaaattagt
gactgtacaacaggtgttccaacagctgcagttgcaataaaatataaagatgaaattata
aaagatgcagctataggtgatggaacaatggatgcaatatttaaaacaattgatagaata
acaggttatgcaggagagttaaaagattataaagttatctctgtaactgaggggaaagat
gctttagcaaaagttacaacaagagtatcttttgattcaacaagtccagcttttgttggt
catggtttgagtattgatacaatgttagctactgcaaaagcgtatttaggagcattaaac
tcatatctttcacaaaaagagagactttctaaaaaatctgaacatcaagtataa
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