Aeromicrobium sp. A1-2: C6I20_04715
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Entry
C6I20_04715 CDS
T05642
Symbol
leuC
Name
(GenBank) 3-isopropylmalate dehydratase large subunit
KO
K01703
3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:
4.2.1.33
4.2.1.35
]
Organism
aeb
Aeromicrobium sp. A1-2
Pathway
aeb00290
Valine, leucine and isoleucine biosynthesis
aeb00660
C5-Branched dibasic acid metabolism
aeb01100
Metabolic pathways
aeb01110
Biosynthesis of secondary metabolites
aeb01210
2-Oxocarboxylic acid metabolism
aeb01230
Biosynthesis of amino acids
Module
aeb_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
aeb00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00660 C5-Branched dibasic acid metabolism
C6I20_04715 (leuC)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
C6I20_04715 (leuC)
Enzymes [BR:
aeb01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.33 3-isopropylmalate dehydratase
C6I20_04715 (leuC)
4.2.1.35 (R)-2-methylmalate dehydratase
C6I20_04715 (leuC)
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Motif
Pfam:
Aconitase
Motif
Other DBs
NCBI-ProteinID:
AXT84568
UniProt:
A0A3B7DFM0
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Position
969627..971048
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AA seq
473 aa
AA seq
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MGKTLAEKIWEEHVVRRHEGEPDLLYIDLHLIHEVTSPQAFDGLRIAGRPVRRPDLTLAT
EDHNIPTTDLDKPIADLVSRTQVETLRRNCAEFGVRLHPMGDIDQGIVHVVGPQLGLTQP
GMTIVCGDSHTSTHGAFGSIAFGIGTSEVEHVLATQSLSQAKPKMMAVDVVGDLPTGSTA
KDLILALITQETTGGGQGYIVEYRGDAIRALSMEARMTICNMSIEWGAKAGLIAPDQVTY
DYLEGRPNAPVGGDWDAAVAHWDSLVTDEDAEFDKVITIDASTITPFVTWGTNPGQGVPL
SGNVPDPASFEDDNERIAAENALRYMGLEAGTPMKDIKVDTVFIGSCTNGRIEDLRVAAA
LMEGHKVADDTRILVVPGSVRVRLQAEQEGLDVIFKDAGAEWRGAGCSMCLGMNPDQLMV
GERAASTSNRNFEGRQGKGGRTHLVSPDVAVATGILGHLAGPADLAQLEKAGA
NT seq
1422 nt
NT seq
+upstream
nt +downstream
nt
atgggcaagaccctggccgagaagatctgggaagagcacgtcgtccgccgccacgaaggt
gagccggatctgctctacatcgatctgcacctgatccacgaagtcacgagtccgcaggcc
tttgacggcctccggatcgctggccgtccggtacgtcgtcctgacctcacgttggcgacc
gaggaccacaacatcccgacgaccgatctcgacaagccgatcgccgacctggtgtcccgc
acccaggtcgagacgcttcgccgcaactgcgccgagttcggcgtccgactgcaccccatg
ggtgacatcgaccagggcatcgtgcacgtcgtcggaccgcagctgggtctgactcagccg
ggcatgacgatcgtctgcggtgactcgcacacctcgacgcacggcgcgttcggctcgatc
gccttcggcatcggcacttccgaggtcgagcacgtgctcgcgacacagtcgctgtcgcag
gccaagcccaagatgatggccgtcgacgtcgtcggcgacctgccgaccggctcgaccgcc
aaggacctgatcctggcgctcatcacgcaggagaccaccggtggcggccagggctacatc
gtggagtaccgcggcgacgcaatccgtgcgctgtcgatggaagcccgcatgacgatctgc
aacatgtcgatcgagtggggcgcgaaggccggactcatcgcacccgaccaggtgacgtac
gactacctcgagggtcgccccaacgcgcccgtgggtggtgactgggatgccgcggtcgcg
cactgggacagcctggtgaccgacgaagacgccgagttcgacaaggtcatcacgatcgac
gcctcgaccatcacgccgttcgtcacgtgggggaccaaccccggccagggcgtgccgctg
tcgggcaacgttccggaccccgcctcgttcgaggacgacaacgagcggatcgctgccgag
aacgccctgcggtacatggggctcgaggccggtacgccgatgaaggacatcaaggtcgac
acggtcttcatcggatcgtgcaccaacggtcggatcgaggacctgcgggtcgcggccgcc
ctgatggagggccacaaggtcgccgacgacacccgcatcctggtcgtgccgggatcggtc
cgcgtacgtctgcaggccgagcaggaaggcctcgacgtgatcttcaaggacgctggcgcc
gagtggcgcggcgcgggctgctcgatgtgcctgggcatgaaccccgaccagctgatggtg
ggggagcgtgcggcctcgacgtccaaccgcaacttcgaaggacgccagggcaagggcggc
cgtacgcacctcgtgtcgcccgacgtcgcggtggccaccggaatcctcggccacctggcc
ggaccggccgacctggcccagctcgagaaggcaggagcctga
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