Aeromicrobium sp. A1-2: C6I20_05670
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Entry
C6I20_05670 CDS
T05642
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
aeb
Aeromicrobium sp. A1-2
Pathway
aeb00300
Lysine biosynthesis
aeb00550
Peptidoglycan biosynthesis
aeb01100
Metabolic pathways
aeb01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
aeb00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
C6I20_05670
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
C6I20_05670
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
C6I20_05670
Enzymes [BR:
aeb01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
C6I20_05670
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
Phage_fiber_2
Motif
Other DBs
NCBI-ProteinID:
AXT84731
UniProt:
A0A3B7D4I7
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Position
1149680..1151026
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AA seq
448 aa
AA seq
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MIPLSLRDIAVATGGVVSGDERIVVDAPATVDSRAIEVGGLFVAVAGDRVDGHDYVEQAM
AAGAAAVLSSREVGVPSVVVANVTEALGRLARHVLDLAEDITVVAITGSSGKTSTKDLLA
QVLEPEGSTIATVGNFNNELGVPLTVLHVDELTRFLVVEMGARGIGDIAALCRIAPPSVG
VVLNVGRAHIGEFGSAEAIARTKGELVEAVNQDGVAVLNADDALVLAMAERTDGAIMTFG
VAGDVEVADVRVDESGSPHFTLRHGGRSVGVQVPLIGEYHVANAAAAATVALALGVGLAT
IAGRFATALPRSSMRMERHVREDGVVIVNDAYNANPESMAAALRAVAAIGNGRAVAVLGE
MLELGDGSHEAHRQIGLLAAELGFLRVVAVGEGARGIVEGAGGIAVSVDTVDVAVHTLSA
SLSGDEVVLVKASRGGRLERVADALLEG
NT seq
1347 nt
NT seq
+upstream
nt +downstream
nt
atgatcccgctctcgctccgggacatcgccgtcgcgacgggcggcgtcgtgagcggcgac
gaacgcattgtcgtcgacgcacccgcgacggtcgactcgcgtgcgatcgaggtcggcggc
ctgttcgtcgcggtggccggagaccgcgtcgacggtcacgactacgtcgagcaggccatg
gcagcgggcgccgcagccgttctcagcagtcgtgaggtcggggttccatcggtcgtcgtc
gccaacgtcaccgaggccctgggccgcctggcccgtcacgtgctcgacctggccgaggac
atcacggtggtcgcgatcaccggctccagcggcaagaccagcaccaaggacctgttggca
caggtgctcgagcccgaggggagcaccatcgcgacggtcggcaacttcaacaacgagctg
ggagtgcccctcacagtcctgcacgtcgacgagctgacccgattcctggtcgtggagatg
ggcgctcgtggcatcggtgacatcgcggcgctgtgccgcatcgccccgccgtccgtcggg
gtcgtgctcaacgtcggtcgcgcgcacatcggcgagttcggctcggcggaggccatcgcg
cgcaccaagggcgagctggtggaggccgtcaaccaggacggcgtcgcggtgctcaatgcc
gacgatgcgctggtgctggcgatggcggagcgcaccgatggcgcgatcatgacctttggt
gtcgcaggtgacgtcgaggtggccgatgtccgcgtcgacgagtccggctccccgcacttc
actttgcgccacggcgggcgcagcgtcggggtccaggttccgttgatcggggagtaccac
gtcgcgaatgcggctgccgccgcgacggtcgcgctggccctgggggtcgggctggccacg
atcgccggacgcttcgccacagcgctcccgcgatcgtcgatgcggatggaacgtcatgtg
cgcgaggacggcgtcgtgatcgtcaacgacgcgtacaacgccaatccggagtcgatggcc
gcagcgctgagggccgtggccgcgatcggcaacgggcgggcggtcgctgtcctgggggag
atgctcgagctgggggacggcagccatgaggcgcaccggcagatcggccttctcgccgcc
gagctcggttttctccgtgtcgtggcggttggcgagggagctcgggggatcgtcgagggg
gctggcgggatcgccgtctcggtcgacacggtcgatgtggccgtccacacactgtccgcg
agcctttccggggacgaggtcgtacttgtgaaagcatcgaggggcggccggctcgagcgg
gtcgcggacgccctgctggagggctga
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