Aeromonas sp. 2692-1: E5E97_20685
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Entry
E5E97_20685 CDS
T08798
Symbol
thrA
Name
(GenBank) bifunctional aspartate kinase/homoserine dehydrogenase I
KO
K12524
bifunctional aspartokinase / homoserine dehydrogenase 1 [EC:
2.7.2.4
1.1.1.3
]
Organism
aej
Aeromonas sp. 2692-1
Pathway
aej00260
Glycine, serine and threonine metabolism
aej00261
Monobactam biosynthesis
aej00270
Cysteine and methionine metabolism
aej00300
Lysine biosynthesis
aej01100
Metabolic pathways
aej01110
Biosynthesis of secondary metabolites
aej01120
Microbial metabolism in diverse environments
aej01230
Biosynthesis of amino acids
Module
aej_M00016
Lysine biosynthesis, succinyl-DAP pathway, aspartate => lysine
aej_M00017
Methionine biosynthesis, aspartate => homoserine => methionine
aej_M00018
Threonine biosynthesis, aspartate => homoserine => threonine
Brite
KEGG Orthology (KO) [BR:
aej00001
]
09100 Metabolism
09105 Amino acid metabolism
00260 Glycine, serine and threonine metabolism
E5E97_20685 (thrA)
00270 Cysteine and methionine metabolism
E5E97_20685 (thrA)
00300 Lysine biosynthesis
E5E97_20685 (thrA)
09110 Biosynthesis of other secondary metabolites
00261 Monobactam biosynthesis
E5E97_20685 (thrA)
Enzymes [BR:
aej01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.3 homoserine dehydrogenase
E5E97_20685 (thrA)
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.2 Phosphotransferases with a carboxy group as acceptor
2.7.2.4 aspartate kinase
E5E97_20685 (thrA)
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Gene cluster
GFIT
Motif
Pfam:
Homoserine_dh
ACT_9
AA_kinase
NAD_binding_3
ACT_7
ACT
Motif
Other DBs
NCBI-ProteinID:
QJT15089
LinkDB
All DBs
Position
complement(4410413..4412872)
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AA seq
819 aa
AA seq
DB search
MRVLKFGGSSLADAERFLRVADIAVNTHGQSQVALVLSAPAKVTNHLVALVEQTSRGMDA
SSTLFEINGIFSRLLAGLKAAYPALDDKALQARLTSELDQVERLMQGIRLLGLCPDNVQA
RILSRGENLSIAFMHELLRVRGLELDVIVPEQLLVTDGGYLEAHVDIEASRLRFAAKGLR
SDCLYLMPGFTGGSDKGETVLLGRNGSDYSAAVLAACVDAECCEIWTDVEGCYNCDPRLV
PDAYLLKTLSYKEAMELSYFGAKVLHPKTIAPVAQFHIPCLIKNSFNPQGPGTLIGVEQG
DDDLKVKAISDLSGMYMFNVSGPGMKGMVGMAGRIFSAVSRTGVSIVLITQSSSEYSVSF
CIHSYDCDKTRKVLEREFELEFKNQLLDPLEIMQDLAIISLIGDGMRTSKGMAARFFTSL
AQASINIVAIAQGSSERSISAVVRDRKVAEAIKACHQNFFGSQQFIDLFVVGVGGVGAAL
VDQIARQQPVLAEQGTGLRVVGIANSRQMAVNKDGLNLANWREQLVEARDSFSLEAVQKL
VEESHLINPVIVDCTSSEAVAVQYADFLAAGFHVVTPNKKANTGSLDYYKALRRTARQTR
RKFLYETNVGAGLPVIENLQNLIKAGDKLRAFDGVLSGSLSFIFGKLDEGMAFSDATKIA
RGNGFTEPDPRDDLNGMDVARKLLILAREAGMALELSDVEVEQALPPGFDVSGDVEAFMA
RLPEADGWFRDQFAAAQAQGKVLRYVGSIEGGKCKVAIKAVGADEPLFKVKDGENALAFF
STYYQPIPLVLRGYGAGTEVTAAGVFADVLRTQNWKQEL
NT seq
2460 nt
NT seq
+upstream
nt +downstream
nt
atgagagtgttgaagtttggcgggtcgtcactggccgatgcagagcgttttttacgggtc
gccgatatcgcggtgaatacccacggccaatcccaggttgccctggtgctgtcggcaccg
gccaaggtgaccaaccacctggtggcgctggtggagcagaccagccgcggcatggatgcc
agcagcacattgttcgagatcaacggcatcttctcccgcctgctggcaggtttgaaggcg
gcctatcctgcgctggatgacaaagcgctgcaggctcgtctgaccagcgaactggatcag
gtggagcggctgatgcaaggcatccgcctgctggggctctgcccggacaacgtgcaggcc
cgcatcctgagccggggcgagaacctctccatcgccttcatgcacgagctgctgcgagtg
cgcggcctcgagctggacgtcatagtgccggagcagctgctggtgaccgacggcggctat
ctggaggctcacgtcgacatcgaggcctcccgcctgcgcttcgcagccaaggggttgcgt
agcgactgcctttacctgatgccgggcttcaccggcggcagcgacaagggcgaaaccgta
ctgctcggtcgtaacgggtcggattactccgccgccgtgctggccgcctgtgtcgatgcc
gagtgctgcgagatctggaccgacgtcgagggctgttacaactgtgacccgcgcctggtg
ccggatgcctatctgctgaaaaccctctcctacaaggaggcgatggagctctcctacttc
ggtgccaaggtactgcacccgaaaaccatcgcgccggtggcccagttccacattccctgc
ctcatcaagaacagcttcaacccgcaggggccgggcaccttgattggtgtcgagcagggg
gatgacgacctgaaagtgaaggccatctcggatctctccggcatgtacatgttcaacgtc
tccggccccggcatgaagggcatggtcggcatggccggccgcatcttctccgccgtctcc
cgcaccggggtcagcatcgtcctcatcacccagtcatcctccgagtacagcgtcagcttc
tgtatccacagctatgactgcgacaagacccgcaaggtgctggagcgcgagttcgagctg
gagttcaagaaccagctgctggatccgctcgagatcatgcaggatctggcgatcatctcc
ctcatcggtgacggcatgcgcacctccaaggggatggcggcccgcttcttcacctcgctg
gcgcaggcctccatcaacatcgtcgccatcgcccagggctcgagcgagcgctccatctcg
gcggtagtgcgggatcgcaaggtggcggaagccatcaaggcctgccaccagaacttcttc
ggcagccagcagttcatcgatctcttcgtggttggtgtcggcggtgtcggcgcggccctg
gtggatcagattgcccgccagcagccggtattggccgagcagggcaccggcctgcgggtg
gtgggcatcgccaacagccgccaaatggcggtcaacaaggatgggctgaacctcgccaac
tggcgtgaacagctggtggaagcccgtgacagcttcagcctggaagcggtgcaaaagctg
gtggaagagagccacctcatcaacccggtgatcgtcgattgcacctccagcgaggccgtc
gccgtccagtacgccgacttcctcgccgctggtttccacgtggtcaccccgaacaagaag
gccaataccgggtcgctggattactacaaggcgctgcgccgcaccgcccgccagacccgc
cgcaagttcctgtacgagaccaacgtgggcgccggcctgccggtcatcgagaacctgcaa
aacctgatcaaggcaggcgacaagctgcgtgccttcgacggcgtgctgtccggttcgctc
tcctttatcttcggcaagctggacgaagggatggccttctccgacgccaccaagattgcc
cgtggcaacggcttcaccgagccggatccgcgcgacgatctcaacggcatggacgtggcc
cgcaagctgctgatcttggcccgcgaggccggcatggcgctggagctctccgatgtagaa
gtggagcaggcgctgccgccgggctttgatgtgagcggcgatgtggaagcctttatggcc
cgcctgccggaggctgacggctggttccgcgaccagtttgcggccgcccaagctcagggc
aaggtgctgcgctacgtgggttccatcgagggtggcaagtgcaaggtcgccatcaaggcg
gtcggcgccgacgaaccgctgttcaaggtcaaagacggggagaacgcgctcgccttcttc
tctacctactaccagccgatcccgctggtgctgcgcggctatggcgccggtaccgaagtg
accgctgcgggcgtctttgccgacgtgctgcgcacccagaactggaagcaggagttgtaa
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