Adlercreutzia equolifaciens: AEQU_0779
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Entry
AEQU_0779 CDS
T02875
Name
(GenBank) 2-isopropylmalate synthase/homocitrate synthase
KO
K01649
2-isopropylmalate synthase [EC:
2.3.3.13
]
Organism
aeq
Adlercreutzia equolifaciens
Pathway
aeq00290
Valine, leucine and isoleucine biosynthesis
aeq00620
Pyruvate metabolism
aeq01100
Metabolic pathways
aeq01110
Biosynthesis of secondary metabolites
aeq01210
2-Oxocarboxylic acid metabolism
aeq01230
Biosynthesis of amino acids
Module
aeq_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
aeq00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
AEQU_0779
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
AEQU_0779
Enzymes [BR:
aeq01000
]
2. Transferases
2.3 Acyltransferases
2.3.3 Acyl groups converted into alkyl groups on transfer
2.3.3.13 2-isopropylmalate synthase
AEQU_0779
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GFIT
Motif
Pfam:
HMGL-like
LeuA_dimer
HCS_D2
Motif
Other DBs
NCBI-ProteinID:
BAN76748
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Position
1030330..1031931
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AA seq
533 aa
AA seq
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MTATRIYTYDSTLRDGEQCEGITLSLADKLAIVRRLDEFGIDYIEGGFPASNPKDVVFFR
EVAAMDLKHAQIAAFGSTCKKGVAAAEDPGLADLIACGAPVVTIVGKTWDAQVERALQTT
LEENLRMIGESVAHLKAAGRHVVFDAEHYFDGFKANRDYALACVGAAVEAGADSVDLCET
NGGALPFEVEQIVAATVAAFPSQAFGIHCHNDSGCAVANTLAAVRAGATQVQGTVNGIGE
RVGNTDLLTVIADLELKMGAECVGHRSLVQLTGVAQYVAELCNVSMPAHHPYTGSSAFAH
KGGLHASAIARFPAAYEHVSPAAVGNTSRTVVSELAGKASLLAKARSLGFDLEAAGVDVQ
AVLDDIKAREAAGFTYEVADGSLGLLLMRHLRLYAPAFTLESFRVIVDDREDTGALAKDA
LSEATVKIHVGEGRFVATGESAGPVGALDAALRMAIVASYPQVEAMELIDYKVRLLDESQ
GTDAITRVTITATDGVDTWGTVGVSENVIEASWNALVDSLEYGLFRARVRAGK
NT seq
1602 nt
NT seq
+upstream
nt +downstream
nt
atgaccgcgacgcgcatctacacctacgactccaccttgcgcgatggggagcaatgcgag
ggcatcacgctctcgctggccgacaagctcgccatcgtgcggcgtctcgacgagttcggc
atcgactacatcgagggcggcttccctgcgtcgaaccccaaggacgtggtcttcttccgc
gaagtggcggctatggatttgaagcacgcccaaatcgcggccttcggttccacctgcaag
aagggcgtcgccgctgccgaggatcccgggttggccgacctcatcgcgtgcggggcgccg
gtggtcactatcgtcgggaagacgtgggacgcccaggtggagcgcgcgctgcaaacgacg
ctcgaagagaacctgcgcatgatcggcgagtcggtggcccacttgaaggcggctggccgg
catgtggtgttcgatgccgagcactacttcgacggcttcaaagcaaatcgcgactatgcc
ctggcctgcgtgggagcggccgtggaggcgggtgccgattcggtggatctttgcgagacc
aacggaggcgcgctgcccttcgaagtggagcagatcgtcgcagccacagtcgctgccttt
ccgagccaggctttcggcatccactgccacaacgactccggttgcgcggtggccaacacg
ctcgcggccgtgcgcgccggcgccacgcaggtgcagggtaccgtgaacggcatcggcgag
cgcgtgggcaacaccgacctgctcacggtcatcgccgacttggagctgaagatgggtgcg
gaatgcgtggggcaccgcagcctcgtccagcttacaggcgtggcccagtacgtggccgag
ctctgcaacgtgtccatgcccgcgcatcatccctacacgggttcttcggccttcgcccac
aagggcggcttgcacgccagcgccatcgcgcggttccccgccgcctacgagcacgtgagc
cccgccgccgtgggcaacacgagccgcacagtggtgagtgagctggccggcaaggcatcg
cttctggcgaaggcgagaagcctcggcttcgatctggaagcggccggcgtggacgtgcag
gcggtgctcgacgacatcaaggcgcgcgaggcggccggcttcacctacgaggtggccgac
ggctcgctgggccttctgctcatgcgccacctgaggctgtacgcgccggcgttcacgttg
gagagcttccgcgtcatcgtggacgatcgcgaggacacgggagccctggctaaagacgcc
ctgtccgaggccacggtgaagatccacgtgggggaggggcggtttgtggcaacgggcgag
agcgcgggccccgtgggcgccctggacgctgccctgcgcatggccatcgtggcgtcgtat
ccgcaggtggaggccatggagctcatcgactacaaggtgcgtctgctcgacgagtcccag
ggcaccgacgccatcacccgcgtgaccatcaccgccaccgacggcgtagacacctggggc
accgtgggcgtctcggaaaacgtcatcgaggcctcctggaacgcgctcgtcgattccctg
gaatacggccttttccgcgcccgtgtacgggcggggaagtag
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